| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M W Roomi, N W Roomi, T Kalinovsky, M Rath, A Niedzwieck. Marked inhibition of growth and invasive parameters of head and neck squamous carcinoma FaDu by a nutrient mixture. Integrative cancer therapies. vol 8. issue 2. 2009-09-29. PMID:19679626. |
cell proliferation was assessed by mtt assay, matrix metalloproteinase (mmp) secretion by gelatinase zymography, invasion through matrigel, apoptosis by live-green caspases, and cell morphology by hematoxylin-eosin staining. |
2009-09-29 |
2023-08-12 |
mouse |
| Yu Wang, Liguang Sun, Chunhui Xia, Liping Ye, Biao Wan. P38MAPK regulates caspase-3 by binding to caspase-3 in nucleus of human hepatoma Bel-7402 cells during anti-Fas antibody- and actinomycin D-induced apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 63. issue 5. 2009-09-25. PMID:18640003. |
in the present study, therefore, the effect of fa/ad in presence or absence of p38mapk inhibitor sb203580 on the proliferation, apoptosis, p38mapk, caspase-3, location of p38mapk and caspase-3, and interaction between p38mapk and caspase-3 in bel-7402 cell was investigated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (mtt), annexin v-fitc/propidium iodide (pi) double staining, electron microscopy, immunoblot, immunofluorescence and immunoprecipitation/immunoblot assay, respectively. |
2009-09-25 |
2023-08-12 |
human |
| Hellinida Thomadaki, Konstantinos V Floros, Andreas Scorila. Molecular response of HL-60 cells to mitotic inhibitors vincristine and taxol visualized with apoptosis-related gene expressions, including the new member BCL2L12. Annals of the New York Academy of Sciences. vol 1171. 2009-09-23. PMID:19723066. |
the kinetics of cell toxicity were evaluated by the mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] method, trypan blue staining, and cell proliferation efficiency; apoptosis induction was assayed by endonucleosomal cleavage of dna (dna laddering); and the expression levels of the genes were analysed by rt-pcr, using gene-specific primers. |
2009-09-23 |
2023-08-12 |
human |
| Bruna De Felice, Corrado Garbi, Margherita Santoriello, Alessandra Santillo, Robert R Wilso. Differential apoptosis markers in human keloids and hypertrophic scars fibroblasts. Molecular and cellular biochemistry. vol 327. issue 1-2. 2009-09-21. PMID:19224335. |
the extent of apoptosis in this study was investigated by dna fragmentation and mtt assays, propidium iodide staining, p53 expression, and subcellular distribution. |
2009-09-21 |
2023-08-12 |
human |
| Ting-Yan Mi, Xiao-Jun Yan, Hai-Min Chen, Jin Lin, Feng Wang, Wei-Feng X. [Proliferation inhibition of lambda-carrageenan oligosaccharides on HUVEC and expression of apoptotic relevant genes]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 43. issue 5. 2009-09-17. PMID:18717333. |
to study the anti-proliferation effect of lambda-carrageenan oligosaccharides (lambda-co) on human umbilical vein endothelial cells (huvecs) and expression of apoptotic relevant genes, the influence of lambda-co on huvecs proliferation was measured by mtt assay; apoptotic rate, cell cycle distribution and the level of active caspase-3 of huvecs were analyzed using flow cytometry; the mrna level of apoptosis related genes was determined by rt-pcr. |
2009-09-17 |
2023-08-12 |
human |
| Yonghuan Zhao, Sam K C Chang, Gang Qu, Tianwen Li, Hongbin Cu. Beta-sitosterol inhibits cell growth and induces apoptosis in SGC-7901 human stomach cancer cells. Journal of agricultural and food chemistry. vol 57. issue 12. 2009-09-10. PMID:19456133. |
proliferation, cytotoxicity, and apoptosis in sgc-7901 human stomach cancer cells were examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, clone formation, lactate dehydrogenase (ldh) leakage assay, acridine orange (ao)/ethidium bromide (eb) double staining, 4',6-diamidine-2'-phenylindole dihydrochloride (dapi) staining, comet assay, and western blotting. |
2009-09-10 |
2023-08-12 |
human |
| Zhi-Gang Yang, A-Qin Chen, Bo Li. Antiproliferation and apoptosis induced by evodiamine in human colorectal carcinoma cells (COLO-205). Chemistry & biodiversity. vol 6. issue 6. 2009-09-10. PMID:19551742. |
in this study, we investigated the effects of 1 on growth and apoptosis in colo-205 cells by mtt assay, fluorescence microscopy, transmission electron microscopy, dna fragmentation assay, flow cytometry, immunohistochemical analysis, western blotting, and caspase-3 activity assay. |
2009-09-10 |
2023-08-12 |
human |
| R Senthil Kumar, S Arunachalam, V S Periasamy, C P Preethy, A Riyasdeen, M A Akbarsh. Surfactant-cobalt(III) complexes: synthesis, critical micelle concentration (CMC) determination, DNA binding, antimicrobial and cytotoxicity studies. Journal of inorganic biochemistry. vol 103. issue 1. 2009-09-09. PMID:18986707. |
the cytotoxic activity of the complexes on hbl-100 human breast cancer cells was determined adopting mtt assay and specific staining techniques, which revealed that the viability of the cells thus treated was significantly decreased and the cells succumbed to apoptosis as seen in the changes in the nuclear morphology and cytoplasmic features. |
2009-09-09 |
2023-08-12 |
human |
| Jing Zhang, Difeng Zhu, Rong Sheng, Honghai Wu, Yongzhou Hu, Feng Wang, Tianyu Cai, Bo Yang, Qiaojun H. BZYX, a novel acetylcholinesterase inhibitor, significantly improved chemicals-induced learning and memory impairments on rodents and protected PC12 cells from apoptosis induced by hydrogen peroxide. European journal of pharmacology. vol 613. issue 1-3. 2009-08-28. PMID:19345205. |
mtt assay and annexin v-fitc apoptosis detection showed the viability of pc12 cells remarkably decreased with 400 microm h(2)o(2), while it significantly increased when the cells were pretreated with 0.1-1.0 microm bzyx. |
2009-08-28 |
2023-08-12 |
Not clear |
| Jun Xu, De-Fu Gao, Guo-Li Yan, Jian-Ming Fa. Induced apoptotic action of recombinant trichosanthin in human stomach adenocarcinoma MCG803 cells. Molecular biology reports. vol 36. issue 6. 2009-08-17. PMID:18773305. |
mtt assay was adopted to measure the growth inhibition ratio of mcg803 cells treated with tcs and apoptosis was assayed by agarose gel electrophoresis. |
2009-08-17 |
2023-08-12 |
human |
| Yu Kan Liu, Qiao Zhi Lu, Rui Pei, Hui Jiao Ji, Guo Shun Zhou, Xiao Li Zhao, Rui Kang Tang, Ming Zhan. The effect of extracellular calcium and inorganic phosphate on the growth and osteogenic differentiation of mesenchymal stem cells in vitro: implication for bone tissue engineering. Biomedical materials (Bristol, England). vol 4. issue 2. 2009-08-13. PMID:19208939. |
their proliferation, apoptosis, mineralization and osteogenic differentiation were determined by the mtt assay, tunel assay, vonkossa stain and rt-pcr examination. |
2009-08-13 |
2023-08-12 |
Not clear |
| Xiao-Li Mai, Zhan-Long Ma, Jun-Hui Sun, Sheng-Hong Ju, Ming Ma, Gao-Jun Ten. Assessments of proliferation capacity and viability of New Zealand rabbit peripheral blood endothelial progenitor cells labeled with superparamagnetic particles. Cell transplantation. vol 18. issue 2. 2009-08-13. PMID:19499705. |
tetrazolium salt (mtt) assay, cell apoptosis, and cycle detection were assessed to evaluate proliferation and function of various concentrations, magnetically labeled epcs. |
2009-08-13 |
2023-08-12 |
rabbit |
| Yang Yang, Lan Chen, Hua-Zhen Pan, Yi Kou, Cai-Min X. Glycosylation modification of human prion protein provokes apoptosis in HeLa cells in vitro. BMB reports. vol 42. issue 6. 2009-08-12. PMID:19558790. |
the effect of apoptosis induced by prp mutants was confirmed by mtt assay, hochest staining, annexin-v staining and pi staining. |
2009-08-12 |
2023-08-12 |
human |
| C Chen, P Tang, J Yue, P Ren, X Liu, X Zhao, Z Y. Effect of siRNA targeting HIF-1alpha combined L-ascorbate on biological behavior of hypoxic MiaPaCa2 cells. Technology in cancer research & treatment. vol 8. issue 3. 2009-08-11. PMID:19445542. |
then, we observed the expression of hif-1alpha mrna and protein, the proliferation, apoptosis, and migration of miapaca2 cells by real-time pcr, western blot, mtt, tunel, and transwell assay, respectively. |
2009-08-11 |
2023-08-12 |
human |
| Limin Cai, Xiaomei Li, Shuyun Zheng, Yanhua Wang, Yandong Wang, Haiyan Li, Jing Yang, Jianfang Su. Inhibitor of growth 4 is involved in melanomagenesis and induces growth suppression and apoptosis in melanoma cell line M14. Melanoma research. vol 19. issue 1. 2009-07-30. PMID:19430401. |
the effects and mechanisms of ing4 on proliferation and apoptosis of m14 cells were analyzed in vitro according to mtt assay, colony formation assay, and tunel assay. |
2009-07-30 |
2023-08-12 |
human |
| Jing Zhang, Yong Cheng, Jun-Tian Zhan. [Protective effect of (-) clausenamide against neurotoxicity induced by okadaic acid and beta-amyloid peptide25-35]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 42. issue 9. 2009-07-27. PMID:18050734. |
pretreatment of (-) clausenamide and licl decreased the rate of cell death from mtt, ldh release, and apoptosis from hoechst 33258 staining in sh-sy5y cell line. |
2009-07-27 |
2023-08-12 |
rat |
| Yongbiao Zheng, Baobing Zhao, Chunhua Lu, Xinjian Lin, Zhonghui Zheng, Wenjin S. Isolation, structure elucidation and apoptosis-inducing activity of new compounds from the edible fungus Lentinus striguellus. Natural product communications. vol 4. issue 4. 2009-07-20. PMID:19475993. |
striguellone a showed cytotoxicity against hela cells by mtt assay and was found to be an activator of apoptosis, assessed by morphological observation and cell cycle analysis using the flow cytometer. |
2009-07-20 |
2023-08-12 |
Not clear |
| Yali Liu, Yanqing Zhong, Jianming Pei, Yunlong Zhu, Yuzhen Hu, Sumin Chi, Alan D Kay. Inhibitory effect of leptin on growth hormone secretion of GH3 cells: involvement of cell proliferation, apoptosis and intracellular free Ca2+. Cytokine. vol 46. issue 2. 2009-07-15. PMID:19297186. |
cell proliferation was evaluated by mtt (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide) assay, distribution of cell cycle and rate of apoptosis determined by flow cytometry and fluorescence microscopy, and intracellular free ca(2+) levels ([ca(2+)](i)) of single gh3 cells measured by a laser scanning confocal microscope. |
2009-07-15 |
2023-08-12 |
Not clear |
| Juan Li, Peishu Liu, Hongluan Mao, Ancong Wanga, Xiaolei Zhan. Emodin sensitizes paclitaxel-resistant human ovarian cancer cells to paclitaxel-induced apoptosis in vitro. Oncology reports. vol 21. issue 6. 2009-07-09. PMID:19424643. |
cells were treated with different concentration of emodin alone or combined with paclitaxel, then the cell viability was measured by mtt and the apoptosis was determined by flow cytometric analysis. |
2009-07-09 |
2023-08-12 |
human |
| Jia-Kun Shen, Hua-Ping Du, Min Yang, Yun-Gui Wang, Jie Ji. Casticin induces leukemic cell death through apoptosis and mitotic catastrophe. Annals of hematology. vol 88. issue 8. 2009-07-07. PMID:19139893. |
cell viability was measured by mtt method; apoptosis and cell cycle arrest were determined by flow cytometry, av-pi assay, and dna fragmentation assay. |
2009-07-07 |
2023-08-12 |
Not clear |