| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Xiang, Yong Fang, Shi-Xuan Wan. Quercetin suppresses HeLa cells by blocking PI3K/Akt pathway. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 34. issue 5. 2015-04-28. PMID:25318886. |
cell viability was evaluated by mtt assay, cell apoptosis was detected by annexin-v/pi double labeled cytometry and dna ladder assay. |
2015-04-28 |
2023-08-13 |
human |
| Mei-Ying Qi, Xin Liu, Bao-Lan Liu, Nai-Cen Zhou, Bo X. [Effect of mitoxantrone on proliferation and apoptosis of human multiple myeloma cell RPMI8226]. Zhongguo shi yan xue ye xue za zhi. vol 22. issue 6. 2015-04-22. PMID:25543488. |
the inhibitory rate of rpmi8226 cells proliferation was assayed by mtt, the morphological changes of rpmi-8226 cells were observed by inverted flurescent microscopy and transmission electron microscopy, the apoptosis rate and the cell cycle distribution of rpmi-8226 cells were detected by flow cytometry. |
2015-04-22 |
2023-08-13 |
human |
| Kailiang Zhang, Shanjun Zhu, Yanwei Liu, Xiaoqun Dong, Zhendong Shi, Anling Zhang, Chaoyong Liu, Luyue Chen, Jianwei Wei, Peiyu Pu, Jianning Zhang, Tao Jiang, Lei Han, Chunsheng Kan. ICAT inhibits glioblastoma cell proliferation by suppressing Wnt/β-catenin activity. Cancer letters. vol 357. issue 1. 2015-04-21. PMID:25434796. |
mtt assay, flow cytometry and cell invasion assay were used to detect cell proliferation, cell cycle distribution, apoptosis and invasion. |
2015-04-21 |
2023-08-13 |
human |
| Meng-meng Lv, Xing-ya Zhu, Wei-xian Chen, Shan-liang Zhong, Qing Hu, Teng-fei Ma, Jun Zhang, Lin Chen, Jin-hai Tang, Jian-hua Zha. Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 11. 2015-04-17. PMID:25077924. |
drug resistance was assessed by apoptosis assay and mtt examination. |
2015-04-17 |
2023-08-13 |
Not clear |
| Joshua Runtuwene, Haruka Amitani, Marie Amitani, Akihiro Asakawa, Kai-Chun Cheng, Akio Inu. Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. PeerJ. vol 3. 2015-04-14. PMID:25870767. |
the survival rate was determined using the kaplan-meier survival test, and cell viability was assessed using cell viability imaging kit and the mtt assay, and activation of the cell apoptosis pathway (phosphorylated adenosine monophosphate activated protein kinase (p-ampk), apoptosis-inducing factor (aif) and caspase 3) were characterized by western blots. |
2015-04-14 |
2023-08-13 |
mouse |
| Yong-Zhan Zhen, Ya-Jun Lin, Kai-Ji Li, Xiao-Shan Yang, Yu-Fang Zhao, Jie Wei, Jing-Bo Wei, Gang H. Gambogic Acid lysinate induces apoptosis in breast cancer mcf-7 cells by increasing reactive oxygen species. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-04-13. PMID:25866542. |
inhibition of cell proliferation was determined by mtt assay; intracellular ros level was detected by staining cells with dcfh-da; cell apoptosis was determined by flow cytometer and the mechanism of gal was investigated by western blot. |
2015-04-13 |
2023-08-13 |
human |
| BeiLi Zhang, Yan G. Bortezomib inhibits gastric carcinoma HGC-27 cells through the phospho-Jun N-terminal kinase (p-JNK) pathway in vitro. Gene. vol 559. issue 2. 2015-04-10. PMID:25602436. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay revealed that the bortezomib significantly decreased the viability of hgc-27 cells and induced apoptosis. |
2015-04-10 |
2023-08-13 |
human |
| Qiaoyu Sun, Ya Ou, Shujuan Wang, Xiaodong Yuan, Wenjiang Zhang, Hongliang Deng, Lili Zhan. The effect of autophagy in the process of adipose-derived stromal cells differentiation into astrocytes. Journal of molecular neuroscience : MN. vol 53. issue 4. 2015-04-06. PMID:24420732. |
by methyl thiazolyl tetrazolium (mtt) assay, we found that the number of living cells was reduced gradually, and early apoptosis rate was increased by flow cytometry. |
2015-04-06 |
2023-08-12 |
Not clear |
| X L Wang, M Y Liu, S M Sun, X L Liu, L Yu, X R Wang, L X Chu, B Rosenthal, H N Shi, P Boireau, F Wang, Y Zhao, X P W. An anti-tumor protein produced by Trichinella spiralis induces apoptosis in human hepatoma H7402 cells. Veterinary parasitology. vol 194. issue 2-4. 2015-04-02. PMID:23433602. |
the results show that the expressed target gene successfully induced apoptosis in h7402 cells as measured by hoechst-pi staining, mtt assay (p<0.05). |
2015-04-02 |
2023-08-12 |
human |
| Marzieh Badinloo, Saeed Esmaeili-Mahan. Phosphatidylinositol 3-kinases inhibitor LY294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines. Fundamental & clinical pharmacology. vol 28. issue 4. 2015-03-30. PMID:23837575. |
cell viability was determined by mtt assay, and the induction of apoptosis was assessed by immunoblotting of caspase-3. |
2015-03-30 |
2023-08-12 |
human |
| Xiaochen Yu, Yang Wang, Wenhui Zhao, Haizhou Zhou, Wei Yang, Xiuru Gua. Toll-like receptor 7 promotes the apoptosis of THP-1-derived macrophages through the CHOP-dependent pathway. International journal of molecular medicine. vol 34. issue 3. 2015-03-30. PMID:24994112. |
cell viability and apoptosis were detected by 3-(4,5-dimethylthiazol-2-y-1)‑2,5-diphenyl-2h-tetrazolium bromide (mtt) assay and flow cytometry, respectively. |
2015-03-30 |
2023-08-13 |
Not clear |
| Jiaoyang Luo, Weijun Kong, Meihua Yan. HJC, a new arylnaphthalene lignan isolated from Justicia procumbens, causes apoptosis and caspase activation in K562 leukemia cells. Journal of pharmacological sciences. vol 125. issue 4. 2015-03-30. PMID:25141923. |
the chemical structure of hjc was validated by lc-esi-ms/ms, cytotoxicity was assayed using mtt, and apoptosis was investigated by flow cytometry. |
2015-03-30 |
2023-08-13 |
human |
| Jia-Xin Fan, Ying-Jian Zeng, Jian-Wei Wu, Zhang-Qiu Li, Yuan-Ming Li, Rong Zheng, Guang-Yang Weng, Kun-Yuan Gu. [Synergistic killing effect of arsenic trioxide combined with curcumin on KG1a cells]. Zhongguo shi yan xue ye xue za zhi. vol 22. issue 5. 2015-03-30. PMID:25338570. |
the cell survival rate was mesured by mtt; colony formation capacity was examined by methylcellulose colony formation test; flow cytometry was used to analyse the cell surface molecules, cell apoptosis rate and cell cycle; the cell morphology was observed with wright-giemsa staining and the protein expression of bcl-2, bax, parp was detected by western blot. |
2015-03-30 |
2023-08-13 |
Not clear |
| Ying Wang, Yu-Xiang Han, Zhi-Yun Niu, Xing-Zhe Wang, Huan Hua, Yin-Tao Shang, Fu-Xu Wang, Xue-Jun Zhang, Jian-Min Lu. [BMMSC from blastic phase CML down-regulate leukemia cell apoptosis]. Zhongguo shi yan xue ye xue za zhi. vol 22. issue 5. 2015-03-30. PMID:25338597. |
k562 cells and primary cml-bp cells were co-cultured with bmmsc of different groups; the cell proliferation was detected by mtt method, the cell apoptosis rate and mitochondrial membrane potential were measured by flow cytometry, the expression levels of caspase-8, caspase-9, and activated caspase-3 in cells were measured by western blot. |
2015-03-30 |
2023-08-13 |
Not clear |
| Raimundo Fernandes de Araújo Júnior, Ana Luiza C S Leitão Oliveira, Raniere Fagundes de Melo Silveira, Hugo Alexandre de Oliveira Rocha, Pedro de França Cavalcanti, Aurigena Antunes de Araúj. Telmisartan induces apoptosis and regulates Bcl-2 in human renal cancer cells. Experimental biology and medicine (Maywood, N.J.). vol 240. issue 1. 2015-03-23. PMID:25125501. |
both types of cells were treated with telmisartan for 4 h, 24 h, and 48 h, and then were assayed for levels of apoptosis, caspase-3, and bcl-2 using mtt assays, flow cytometry, and immunostaining studies. |
2015-03-23 |
2023-08-13 |
human |
| Min-Chul Kim, Bora Lim, Hee-Jung Lee, Hyung-Woo Kim, Young-Kyu Kwon, Byung-Joo Ki. Effects of sophorae radix on human gastric and colorectal adenocarcinoma cells: sophorae radix and cancer cells. Journal of pharmacopuncture. vol 15. issue 2. 2015-03-17. PMID:25780637. |
also, we showed that sr induced apoptosis in mkn-45 and widr cells by using the mtt assay, the caspase 3 assay and the sub-g1 analysis. |
2015-03-17 |
2023-08-13 |
human |
| Yue Xing, Di Yang, Jing Lu, De-Li Don. Insulin prevents bone morphogenetic protein-4 induced cardiomyocyte apoptosis through activating Akt. Biochemical and biophysical research communications. vol 456. issue 2. 2015-03-13. PMID:25490386. |
cell viability and apoptosis were measured by using mtt, live and dead staining, caspase-3 activity assays, and the protein expressions were measured by using western blot technique. |
2015-03-13 |
2023-08-13 |
Not clear |
| Qi Deng, Xinling Yan. Protective effects of Gynostemma pentaphyllum polysaccharides on PC12 cells impaired by MPP(+). International journal of biological macromolecules. vol 69. 2015-03-12. PMID:24875324. |
our results indicated that exposure of pc12 cells to 1mm mpp(+) significantly decreased the cell viability when examined by mtt assay, ldh assay, and annexin-v-fitc and propidium iodide (pi) apoptosis detection assays. |
2015-03-12 |
2023-08-13 |
Not clear |
| Qingbing Meng, Jie Zhao, Hongbing Liu, Guoyou Zhou, Wensheng Zhang, Xingli Xu, Minqian Zhen. HMGB1 promotes cellular proliferation and invasion, suppresses cellular apoptosis in osteosarcoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 12. 2015-03-10. PMID:25168370. |
then the changes in proliferation, apoptosis, and invasion of mg-63 cells were examined by mtt test, pi staining, annexin v staining, and transwell chamber assay. |
2015-03-10 |
2023-08-13 |
human |
| Dongyong Zhang, Ang Tian, Xiangxin Xue, Mei Wang, Bo Qiu, Anhua W. The effect of temozolomide/poly(lactide-co-glycolide) (PLGA)/nano-hydroxyapatite microspheres on glioma U87 cells behavior. International journal of molecular sciences. vol 13. issue 1. 2015-02-26. PMID:22312307. |
the proliferation, apoptosis and invasion of glioma cells were evaluated by mtt, flow cytometry assay and transwell assay. |
2015-02-26 |
2023-08-12 |
Not clear |