| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shujie He, Caiyun G Li, Lynn Slobbe, Amy Glover, Elaine Marshall, Bruce C Baguley, Michael R Eccle. PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression. Melanoma research. vol 21. issue 1. 2014-12-18. PMID:21164369. |
by mtt cell proliferation and flow cytometry assays, both mitf and pax3 proteins seemed to be functional, as knockdown with sirna led to reduced proliferation and induction of apoptosis. |
2014-12-18 |
2023-08-12 |
Not clear |
| Min Chul Kim, Hee Jung Lee, Bora Lim, Ki-Tae Ha, Sung Young Kim, Insuk So, Byung Joo Ki. Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. International journal of molecular medicine. vol 33. issue 6. 2014-12-18. PMID:24647664. |
ags cell viability was assessed by mtt assay and flow cytometric analysis, mitochondrial membrane depolarization was assessed, and caspase-3 was used to determine the involvement of apoptosis. |
2014-12-18 |
2023-08-12 |
human |
| Min Chul Kim, Hee Jung Lee, Bora Lim, Ki-Tae Ha, Sung Young Kim, Insuk So, Byung Joo Ki. Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. International journal of molecular medicine. vol 33. issue 6. 2014-12-18. PMID:24647664. |
to investigate the signaling pathway of quercetin-induced apoptosis in the ags cells, western blot analysis and mtt assay were performed. |
2014-12-18 |
2023-08-12 |
human |
| Min Liu, Chun-Mei Li, Zhao-Feng Chen, Ri Ji, Qing-Hong Guo, Qiang Li, Hong-Ling Zhang, Yong-Ning Zho. Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells. International journal of molecular medicine. vol 33. issue 6. 2014-12-18. PMID:24676394. |
the inhibition of cell proliferation was determined using mtt assay, cell apoptosis was monitored by terminal deoxynucleotidyl transferase-mediated dutp nick end‑labeling (tunel) and flow cytometry, and cell ultrastructural changes were assessed via transmission electron microscopy. |
2014-12-18 |
2023-08-12 |
human |
| Li Zhang, Yanxin Zheng, Hongzhu Deng, Lei Liang, Juan Pen. Aloperine induces G2/M phase cell cycle arrest and apoptosis in HCT116 human colon cancer cells. International journal of molecular medicine. vol 33. issue 6. 2014-12-18. PMID:24682388. |
alo inhibited proliferation and induced apoptosis in hct116 cells in a dose- and time-dependent manner as detected by mtt, clonogenic survival, and flow cytometric assays. |
2014-12-18 |
2023-08-12 |
human |
| Lisheng Cai, Xudong Ma, Yiqun Huang, Yong Zou, Xingsheng Che. Aberrant histone methylation and the effect of Suv39H1 siRNA on gastric carcinoma. Oncology reports. vol 31. issue 6. 2014-12-17. PMID:24737085. |
suv39h1 was depleted by sirna, and cell apoptosis and cell proliferation were assessed by tunel and mtt assays, respectively. |
2014-12-17 |
2023-08-13 |
Not clear |
| Deguang Xing, Jun Wang, Shaowu Ou, Yunjie Wang, Bo Qiu, Daling Ding, Feng Guo, Qinghua Ga. Expression of neonatal Nav1.5 in human brain astrocytoma and its effect on proliferation, invasion and apoptosis of astrocytoma cells. Oncology reports. vol 31. issue 6. 2014-12-17. PMID:24756536. |
the mtt, wound healing, matrigel invasion and flow cytometric assays confirmed that following sirna downregulation of the expression of the scn5a/nnav1.5 gene, the in vitro proliferation and in vitro invasiveness of the u251 cells were significantly reduced (p<0.05 for both comparisons), and the apoptosis rate was significantly increased (p<0.05). |
2014-12-17 |
2023-08-13 |
human |
| Filiz Özdemir, Gülşen Akalın, Mesut Şen, Nur Ipek Önder, Arzu Işcan, H Mehtap Kutlu, Zerrin Inces. Towards novel anti-tumor strategies for hepatic cancer: ɛ-viniferin in combination with vincristine displays pharmacodynamic synergy at lower doses in HepG2 cells. Omics : a journal of integrative biology. vol 18. issue 5. 2014-12-15. PMID:24341688. |
growth inhibition and apoptosis induction were determined by mtt assay and annexin v/propidium iodide (pi), respectively. |
2014-12-15 |
2023-08-12 |
Not clear |
| Huanlong Liu, Xueyan Chen, Yu Han, Chaoyi Li, Pingping Chen, Suwen Su, Yongjian Zhang, Zhenhua Pa. Rho kinase inhibition by fasudil suppresses lipopolysaccharide-induced apoptosis of rat pulmonary microvascular endothelial cells via JNK and p38 MAPK pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 68. issue 3. 2014-12-12. PMID:24406296. |
the results suggested that fasudil effectively prevented lps-induced injury of rat pmvecs, as determined by mtt assay, ldh activity assay, apoptosis and western blot analysis of apoptosis-related proteins bcl-2 and bax. |
2014-12-12 |
2023-08-12 |
rat |
| Duo-Xuan Shi, Liang-Ming Ma, Yu-Jin Lu, Bo Ba. [Apoptosis-inducing effect of tetrandrine and imatinib on K562/G01 cells and its related mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 22. issue 3. 2014-12-11. PMID:24989284. |
mtt assay was used to detect the inhibitory effect of drugs on cell growth, flow cytometry was used to detect the cell cycle and apoptosis rate. |
2014-12-11 |
2023-08-13 |
Not clear |
| B Zhang, H S Zhou, Q Cheng, L Lei, B H. Low-frequency ultrasound induces apoptosis of rat aortic smooth muscle cells (A7r5) via the intrinsic apoptotic pathway. Genetics and molecular research : GMR. vol 13. issue 2. 2014-12-10. PMID:24782171. |
cell viability and apoptosis of a7r5 cells were evaluated after treating a7r5 cells with a continuous 45-khz 1.0-w/cm(2) ultrasound (exposure time of 0, 10, 20, 30, and 35 s) by mtt assay and flow cytometry. |
2014-12-10 |
2023-08-13 |
rat |
| Lijuan Wang, Suxia Han, Guihua Jin, Xia Zhou, Meng Li, Xia Ying, Le Wang, Huili Wu, Qing Zh. Linc00963: a novel, long non-coding RNA involved in the transition of prostate cancer from androgen-dependence to androgen-independence. International journal of oncology. vol 44. issue 6. 2014-12-09. PMID:24691949. |
the functions of linc00963 on cell proliferation, apoptosis, migration and invasion were evaluated by a knockdown strategy in vitro using mtt, flow cytometric analysis and transwell chamber assays. |
2014-12-09 |
2023-08-13 |
Not clear |
| David M Small, Christudas Morais, Jeff S Coombes, Nigel C Bennett, David W Johnson, Glenda C Gob. Oxidative stress-induced alterations in PPAR-γ and associated mitochondrial destabilization contribute to kidney cell apoptosis. American journal of physiology. Renal physiology. vol 307. issue 7. 2014-12-09. PMID:25122050. |
hk-2 pte cells were subjected to oxidative stress (0.2-1.0 mm h₂o₂) for 2 and 18 h and compared with untreated cells for apoptosis, mitosis (morphology/biomarkers), cell viability (mtt), superoxide (dihydroethidium), mitochondrial function (mitotracker red and jc-1), atp (luminescence), and mitochondrial ultrastructure. |
2014-12-09 |
2023-08-13 |
Not clear |
| Juan Yin, Nanshun Wu, Fanqing Zeng, Chao Cheng, Kai Kang, Huan Yan. Paeonol induces apoptosis in human ovarian cancer cells. Acta histochemica. vol 115. issue 8. 2014-12-05. PMID:23768958. |
results measured by mtt (methyl thiazoyltetrazolium) assay showed that cell viability was markedly reduced in a dosage-dependent manner, when treated with paeonol for 24 h. flow cytometry and hoechst staining results indicated that the rate of apoptosis in the paeonol pretreatment group was higher than the control group. |
2014-12-05 |
2023-08-12 |
human |
| Shan-Shan Lin, Bo Zhu, Zi-Kuan Guo, Guo-Zhi Huan. [Protective effect of bone marrow mesenchymal stem cell-derived microvesicles on glutamate injured PC12 cells]. Zhongguo shi yan xue ye xue za zhi. vol 22. issue 4. 2014-12-04. PMID:25130832. |
mtt test was used to evaluate the proliferative status of pc12 cells and the annexinv-fitc detecting kit and hoechst33342 were used to detect the apoptosis of pc12 cells in different groups. |
2014-12-04 |
2023-08-13 |
rat |
| R F Prietsch, L G Monte, F A da Silva, F T Beira, F A B Del Pino, V F Campos, T Collares, L S Pinto, R M Spanevello, G D Gamaro, E Braganho. Genistein induces apoptosis and autophagy in human breast MCF-7 cells by modulating the expression of proapoptotic factors and oxidative stress enzymes. Molecular and cellular biochemistry. vol 390. issue 1-2. 2014-12-03. PMID:24573886. |
mcf-7 cancer and ccd1059sk fibroblast cells were treated with estradiol (10 nm) or genistein (0.01-100 μm) for 24, 48, and 72 h and the cell proliferation was investigated by mtt; membrane cell permeability was evaluated by ldh and pi incorporation; apoptosis was investigated by externalization of phosphatidylserine by facs; and presence of autophagy was detected by lc3a/b immunostaining. |
2014-12-03 |
2023-08-12 |
human |
| Fangbiao Lv, Huilan Yang, Feifei Zhong, Jianyong Fan, Yanhua Liu, Ruidi Ga. [Expression of herpes simplex virus type 2 latency associated transcript ORF1 and its anti-apoptotic function]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 29. issue 12. 2014-12-01. PMID:24660625. |
cells viability was evaluated by mtt assay and cells apoptosis rate was detected by flow cytometry. |
2014-12-01 |
2023-08-12 |
Not clear |
| Fangbiao Lv, Huilan Yang, Feifei Zhong, Jianyong Fan, Yanhua Liu, Ruidi Ga. [Expression of herpes simplex virus type 2 latency associated transcript ORF1 and its anti-apoptotic function]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 29. issue 12. 2014-12-01. PMID:24660625. |
mtt assay showed that the viabilities of vero cells transfected with recombinant plasmid pegfp-orf1 and induced apoptosis by actinomycin d has no statistically significant difference compared with the untreated normal control group (p > 0.05), but remarkable higher than vero cells transfected with empty plasmid pegfp-c2 and induced apoptosis by actinomycin d, the difference was statistically significant (p < 0.05). |
2014-12-01 |
2023-08-12 |
Not clear |
| Yong-Ge Guan, Jin-Bin Liao, Kun-Yin Li, Yu-Cui Li, Yang Song, Jing Ling, Zi-Ren S. Potential mechanisms of an antiadenomyosis chinese herbal formula shaoyao-gancao decoction in primary cell culture model. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-12-01. PMID:25435895. |
effects of sgd, paeoniflorin, and liquiritin on cell proliferation and apoptosis were examined by mtt assay and flow cytometry analyses. |
2014-12-01 |
2023-08-13 |
human |
| Hua Yang, Shi-Ting Tian, Rui-Yun Wu, Yu Chen, Zhi-Nan Mei, Chao-Yuan Wang, Guang-Zhong Yan. Glycoborinine induces apoptosis through mitochondrial pathway in HepG2 cells. Journal of Asian natural products research. vol 16. issue 10. 2014-11-28. PMID:24930917. |
mtt assay result showed that gb inhibited hepg2 cell proliferation in a dose- and time-dependent manner and 50% inhibiting concentration (ic50) of gb-induced cell death was 39.7 μm for a period of 48 h. gb-induced hepg2 apoptosis was confirmed by hochest 33258 staining and pi staining. |
2014-11-28 |
2023-08-13 |
Not clear |