| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luba Hunakova, Paulina Gronesova, Eva Horvathova, Ivan Chalupa, Dana Cholujova, Jozef Duraj, Jan Sedla. Modulation of cisplatin sensitivity in human ovarian carcinoma A2780 and SKOV3 cell lines by sulforaphane. Toxicology letters. vol 230. issue 3. 2014-11-28. PMID:25159039. |
synergy (a2780) and antagonism (skov3) found in mtt assay was confirmed by apoptosis. |
2014-11-28 |
2023-08-13 |
human |
| M Fujiya, H Konishi, M K Mohamed Kamel, N Ueno, Y Inaba, K Moriichi, H Tanabe, K Ikuta, T Ohtake, Y Kohg. microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1. Oncogene. vol 33. issue 40. 2014-11-26. PMID:24166503. |
an mtt assay and xenograft model demonstrated that the transfection of mir-18a induced apoptosis in sw620 cells. |
2014-11-26 |
2023-08-12 |
Not clear |
| Mingyi Wang, Xiangdong Ma, Jian Wang, Lin Wang, Yu Wan. Pretreatment with the γ-secretase inhibitor DAPT sensitizes drug-resistant ovarian cancer cells to cisplatin by downregulation of Notch signaling. International journal of oncology. vol 44. issue 4. 2014-11-26. PMID:24535252. |
ovarian cancer cell lines resistant to cisplatin were treated with dapt, cisplatin or combination for cell viability mtt, flow cytometric cell cycle, elisa apoptosis and colony formation assays. |
2014-11-26 |
2023-08-12 |
human |
| Roja Gopalakrishnan, Bhavani Shanka. Multiple shoot cultures of Ophiorrhiza rugosa var. decumbens Deb and Mondal--a viable renewable source for the continuous production of bioactive Camptotheca alkaloids apart from stems of the parent plant of Nothapodytes foetida (Wight) Sleumer. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 21. issue 3. 2014-11-25. PMID:24252342. |
viability assays using mtt dye were further confirmed by assessing extent of apoptosis in these cells. |
2014-11-25 |
2023-08-12 |
Not clear |
| Huanli Sun, Fenghua Meng, Ru Cheng, Chao Deng, Zhiyuan Zhon. Reduction and pH dual-bioresponsive crosslinked polymersomes for efficient intracellular delivery of proteins and potent induction of cancer cell apoptosis. Acta biomaterialia. vol 10. issue 5. 2014-11-25. PMID:24440420. |
most remarkably, mtt assays showed that cc-loaded dual-sensitive polymersomes induced potent cancer cell apoptosis, in which markedly decreased cell viabilities of 11.3%, 8.1% and 52.7% were observed for mcf-7, hela and 293t cells, respectively, at a cc dosage of 160μgml(-1). |
2014-11-25 |
2023-08-12 |
cattle |
| Haiyan Cui, Changlu Wang, Yurong Wang, Zhenjing Li, Yanan Zhang, Mianhua Chen, Fengjuan L. Pleurotus nebrodensis polysaccharide induces apoptosis in human non-small cell lung cancer A549 cells. Carbohydrate polymers. vol 104. 2014-11-24. PMID:24607184. |
mtt assay showed that pn50g induced apoptosis in the a549 cells in a dose-dependent. |
2014-11-24 |
2023-08-12 |
human |
| Li-Min Zhao, Hong-Yan Kuang, Luo-Xian Zhang, Ji-Zhen Wu, Xian-Liang Chen, Xiao-Yu Zhang, Li-Jun M. Effect of TRPV1 channel on proliferation and apoptosis of airway smooth muscle cells of rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 34. issue 4. 2014-11-21. PMID:25135718. |
mtt assay and hoechst 33258 staining were used to detect the proliferation and apoptosis of asmcs in rats respectively. |
2014-11-21 |
2023-08-13 |
rat |
| Ferda Ari, Serap Celikler, Seyhan Oran, Necmiye Balikci, Sule Ozturk, Mustafa Zafer Ozel, Dilek Ozyurt, Engin Ulukay. Genotoxic, cytotoxic, and apoptotic effects of Hypogymnia physodes (L.) Nyl. on breast cancer cells. Environmental toxicology. vol 29. issue 7. 2014-11-18. PMID:22907900. |
anti-growth effect was tested in two different human breast cancer cell lines (mcf-7 and mda-mb-231) by the mtt and atp viability assays and apoptosis was assayed by the caspase-cleaved cytokeratin 18 (m30-antigen). |
2014-11-18 |
2023-08-12 |
human |
| Zhi-Qiang Jia, Ying Chen, Yong-Xin Yan, Jun-Xia Zha. Iso-suillin isolated from Suillus luteus, induces G1 phase arrest and apoptosis in human hepatoma SMMC-7721 cells. Asian Pacific journal of cancer prevention : APJCP. vol 15. issue 3. 2014-11-18. PMID:24606477. |
we demonstrated the effects of iso-suillin on cell proliferation and apoptosis in smmc-7721 cells, with no apparent toxicity in normal human lymphocytes, using colony formation assays and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) analysis. |
2014-11-18 |
2023-08-12 |
human |
| Xiaoke Zheng, Yanqiu Ou, Minfeng Shu, Youqiong Wang, Yuxi Zhou, Xingwen Su, Wenbo Zhu, Wei Yin, Shifeng Li, Pengxin Qiu, Guangmei Yan, Jingxia Zhang, Jun Hu, Dong X. Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c-Raf/MEK/ERK signaling pathway. Molecular medicine reports. vol 9. issue 5. 2014-11-18. PMID:24626525. |
cell survival and proliferation, cell cycle alterations and apoptosis were analyzed using hoechst staining, the mtt assay, fluorescence microscopy and flow cytometry. |
2014-11-18 |
2023-08-12 |
human |
| Dong-Mei Liu, Zhen-Hui Wang, Li Liu, Xiu-Mei Zhang, Feng-Lan Lo. Acetylpuerarin increases cell viability and reduces apoptosis in rat hippocampal neurons following oxygen‑glucose deprivation/reperfusion. Molecular medicine reports. vol 8. issue 5. 2014-11-13. PMID:24026460. |
neuron viability, apoptosis and caspase-8 and -3 activities were assessed by the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), 4',6-diamidino-2-phenylindole (dapi) and terminal deoxynucleotidyl-transferase-mediated dutp nick end labeling (tunel) and spectrophotometric assays, respectively. |
2014-11-13 |
2023-08-12 |
rat |
| Xiaowei Xu, Baiwen Li, Peijie Huang, Xinjian Wan, Youwen Qin, Lili Zhou, Huixia Liu, Haitao Bai, Yanrong Gao, Chun Wang, Xiangjun Men. Citrate induces apoptosis of the acute monocytic leukemia U937 cell line through regulation of HIF-1α signaling. Molecular medicine reports. vol 8. issue 5. 2014-11-13. PMID:24064771. |
the apoptosis of the aml cell line, u937, was assessed by mtt and hoechst staining, the expression of bcl-2, caspases-3 and -9, hypoxia-inducible factor 1α (hif‑1α) and its target gene glut-1, were assayed by western blotting and the role of hif‑1α was evaluated through sirna. |
2014-11-13 |
2023-08-12 |
Not clear |
| Zuohui Zhang, Zhengzheng Wu, Xiaolei Zhu, Xinchen Hui, Jie Pan, Yun X. Hydroxy-safflor yellow A inhibits neuroinflammation mediated by Aβ₁₋₄₂ in BV-2 cells. Neuroscience letters. vol 562. 2014-11-12. PMID:24412680. |
cell viability and apoptosis were assessed using mtt assay and annexin v/pi staining respectively. |
2014-11-12 |
2023-08-12 |
Not clear |
| James L Figarola, Jyotsana Singhal, Samuel Rahbar, Sanjay Awasthi, Sharad S Singha. LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells. Apoptosis : an international journal on programmed cell death. vol 19. issue 5. 2014-11-12. PMID:24615331. |
cell morphology, cytotoxicity and apoptosis were evaluated by light microscopy, mtt assay, and annexin v-fitc and propidium iodide double staining, respectively. |
2014-11-12 |
2023-08-12 |
human |
| Wei-Wei Guo, Ling Yang, Xiao-Yu Liu, Wen Liu, Ji Zu. [Construction of eukaryotic expression vector of glucose-regulated protein 75 gene deletion mutant and its expression in PC12 cells.]. Sheng li xue bao : [Acta physiologica Sinica]. vol 61. issue 6. 2014-11-08. PMID:20029686. |
hoechst33324 staining was employed to detect cell apoptosis and the results were consistent with the mtt assay results. |
2014-11-08 |
2023-08-12 |
Not clear |
| Y Zhang, Y Chen, C Qu, M Zhou, Q Ni, L X. siRNA targeting prohibitins inhibits proliferation and promotes apoptosis of gastric carcinoma cell line SGC7901 in vitro and in vivo. Cellular and molecular biology (Noisy-le-Grand, France). vol 60. issue 1. 2014-11-07. PMID:24670873. |
the cell proliferation and apoptosis were analyzed by mtt and flow cytometry methods. |
2014-11-07 |
2023-08-12 |
mouse |
| H Zheng, S Xue, Z L Hu, J G Shan, W G Yan. Overexpression of the growth arrest-specific homeobox gene Gax inhibits proliferation, migration, cell cycle progression, and apoptosis in serum-induced vascular smooth muscle cells. Genetics and molecular research : GMR. vol 13. issue 1. 2014-11-06. PMID:24737425. |
the effect of gax overexpression on in vitro serum-induced vsmcs proliferation, migration, cell cycle, and apoptosis was assessed by mtt, wound healing, and flow cytometry assays, respectively. |
2014-11-06 |
2023-08-13 |
rabbit |
| H F Tao, Y S Liu, J L Fang, Y Z Su, F H Chen, L Y Zhou, Y S Zh. Significance of SODD expression in childhood acute lymphoblastic leukemia and its influence on chemotherapy. Genetics and molecular research : GMR. vol 13. issue 1. 2014-11-06. PMID:24737427. |
the sodd rnai-interfering plasmid was constructed and transferred to jurkat cells, and the effects of sodd expression on cell proliferation and apoptosis were analyzed using the mtt and fcm methods. |
2014-11-06 |
2023-08-13 |
Not clear |
| Tarek M K Motawi, Yasser Bustanji, Shohda El-Maraghy, Mutasem O Taha, Mohamed A S Al-Ghussei. Evaluation of naproxen and cromolyn activities against cancer cells viability, proliferation, apoptosis, p53 and gene expression of survivin and caspase-3. Journal of enzyme inhibition and medicinal chemistry. vol 29. issue 2. 2014-11-03. PMID:23368763. |
additionally, we performed cellular viability tests using trypan blue, proliferation mtt assay, apoptosis, p53 and real-time polymerase chain reaction for gene expression of survivin and caspase-3. |
2014-11-03 |
2023-08-12 |
Not clear |
| Yanli Zhang, Shunqin Zhu, Liang Yi, Yaling Liu, Hongjuan Cu. Neurotensin receptor1 antagonist SR48692 reduces proliferation by inducing apoptosis and cell cycle arrest in melanoma cells. Molecular and cellular biochemistry. vol 389. issue 1-2. 2014-11-03. PMID:24357116. |
after sr48692 treatment, cell proliferation was determined by cell counting, mtt assay and brdu incorporation study, the cell cycle and apoptosis were performed by flow cytometry. |
2014-11-03 |
2023-08-12 |
mouse |