| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ai-Ping Feng, Qian Zhang, Min Li, Xin-Nong Jiang, Zong-Yong Zhang, Peng Zhu, Ming-Wei Wang, Shao-Zhong Wei, Li S. High SIPA-1 expression in proximal tubules of human kidneys under pathological conditions. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 35. issue 1. 2015-07-02. PMID:25673195. |
mtt assay and western blotting were employed to evaluate the effects of sipa-1 overexpression on the proliferation and apoptosis of renal cell lines. |
2015-07-02 |
2023-08-13 |
mouse |
| Fei Fei, Dao-Li Zhu, Li-Jun Tao, Bao-Zhu Huang, Hong-Hong Zhan. Protective effect of ATP on skeletal muscle satellite cells damaged by H₂O₂. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 35. issue 1. 2015-07-02. PMID:25673197. |
mtt assay, fitc+pi+dapi fluorescent staining, giemsa staining and immunofluorescence were performed to examine cell viability and apoptosis, and apoptosis-related proteins. |
2015-07-02 |
2023-08-13 |
rat |
| Lijian Xue, Jinhui Li, Yang Li, Chu Chu, Guantao Xie, Jin Qin, Mingfeng Yang, Donggang Zhuang, Liuxin Cui, Huizhen Zhang, Xiaoli F. N-acetylcysteine protects Chinese Hamster ovary cells from oxidative injury and apoptosis induced by microcystin-LR. International journal of clinical and experimental medicine. vol 8. issue 4. 2015-07-01. PMID:26131064. |
cell viability was determined by mtt assay after exposure to nac at various concentrations (0, 1, 5, 10, 20, 30, 40, 50, 60 and 80 mmol/l) alone, or nac (0, 1 and 5 mmol/l) plus mc-lr (0, 2.5, 5 and 10 μg/ml) for 24 h. the reactive oxygen species (ros) in cho cells were measured by dcfh-da, mitochondrial membrane potential (mmp) by fluorescence probe jc-1 staining, and apoptosis index determined by annexin v-pi staining. |
2015-07-01 |
2023-08-13 |
Not clear |
| Song-Tao Xu, Fa-Zhang Zou, Li-Na Cai, Wan-Ling X. The downregulation of OPN inhibits proliferation and migration and regulate activation of Erk1/2 in ECA-109 cells. International journal of clinical and experimental medicine. vol 8. issue 4. 2015-07-01. PMID:26131112. |
the cell proliferation and apoptosis were detected by mtt and hoechst33342 assay. |
2015-07-01 |
2023-08-13 |
human |
| Anil A Chuturgoon, Alisa Phulukdaree, Devapregasan Moodle. Fumonisin B₁ inhibits apoptosis in HepG2 cells by inducing Birc-8/ILP-2. Toxicology letters. vol 235. issue 2. 2015-06-29. PMID:25800559. |
we measured: (i) the level of cell proliferation and cell death mechanism of hepg2 cells (mtt assay, annexin v and propidium iodide staining, jc-1 assay, γh2ax and cleaved parp and hoechst staining); (ii) initiator and executioner caspase activity (luminometric enzyme activity assays); (iii) regulation of mrna expression of pro- and anti- apoptotic molecules using an apoptosis array (qpcr) and (iv) levels of significantly altered apoptosis-related proteins (western blotting) following a 24 h incubation. |
2015-06-29 |
2023-08-13 |
human |
| Guozuo Xiong, Lin Li, Shaowei Sun, Tianping Li, Duanfang Liao, Chang Shu, Qinhui Tu. Subcellular localization of DAXX influence ox-LDL induced apoptosis in macrophages. Molecular biology reports. vol 41. issue 11. 2015-06-26. PMID:25120166. |
mtt and flow cytometry was used to determine cellular viability and apoptosis. |
2015-06-26 |
2023-08-13 |
Not clear |
| Rui Yang, Daozhen Chen, Mengfei Li, Fengqin Miao, Peidang Liu, Qiusha Tan. 20(s)-ginsenoside Rg3-loaded magnetic human serum albumin nanospheres applied to HeLa cervical cancer cells in vitro. Bio-medical materials and engineering. vol 24. issue 6. 2015-06-24. PMID:25226895. |
an antiproliferative effect and cell apoptosis rates of 20(s)-rg3/hsamnp on human cervical cancer cells were determined by the mtt assay and flow cytometry, respectively. |
2015-06-24 |
2023-08-13 |
human |
| Xiaoqing Gao, Jie Du, Guangbi Fan, Chaoxian Yang, Li Deng, Qionglan Yua. Adenoviral-mediated GDNF protects bone marrow mesenchymal stem cells against apoptosis induced by hydrogen peroxide. Bio-medical materials and engineering. vol 24. issue 6. 2015-06-24. PMID:25226915. |
after bmscs infected with ad-gdnf were treated with 500 μm h2o2 at 37° c for 1 h, lactate dehydrogenase (ldh), mtt and tunel methods were used to detect cell viability and apoptosis. |
2015-06-24 |
2023-08-13 |
Not clear |
| Da-Hu Wang, Yu-Jun Zhang, San-Bing Zhang, Hui Liu, Liang Liu, Feng-Ling Liu, Jing Zu. Geldanamycin mediates the apoptosis of gastric carcinoma cells through inhibition of EphA2 protein expression. Oncology reports. vol 32. issue 6. 2015-06-24. PMID:25310629. |
mgc803 cell proliferation and apoptosis were assessed by mtt and fcm, respectively. |
2015-06-24 |
2023-08-13 |
human |
| Xin-Mei Chen, Xian-Biao Xie, Qing Zhao, Fang Wang, Yang Bai, Jun-Qiang Yin, Hong Jiang, Xiao-Lin Xie, Qiang Jia, Gang Huan. Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells. Molecular medicine reports. vol 11. issue 1. 2015-06-24. PMID:25333250. |
cell growth and apoptosis were evaluated by mtt assay and annexin v/propidium iodide double staining and flow cytometry, respectively. |
2015-06-24 |
2023-08-13 |
human |
| Hui-Ping Yu, Song-Tao Qi, Wen-Feng Feng, Guo-Zhong Zhang, He-Ping Zhang, Jin-Jun Tia. Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase. Molecular medicine reports. vol 11. issue 1. 2015-06-24. PMID:25338527. |
the results from an mtt assay and from annexin v-fluorescein isothiocyanate/propidium iodide staining indicated that interference of notch 2 significantly inhibited the proliferation and induced the apoptosis of u251 cells. |
2015-06-24 |
2023-08-13 |
Not clear |
| Wen-Cui Ju, Guo-Bin Huang, Xiao-Yong Luo, Wei-Hua Ren, De-Qing Zheng, Pin-Jia Chen, Yun-Feng Lou, Bin L. X-linked inhibitor of apoptosis-associated factor l (XAFl) enhances the sensitivity of colorectal cancer cells to cisplatin. Medical oncology (Northwood, London, England). vol 31. issue 12. 2015-06-24. PMID:25367849. |
primary crc cells were separated from cancer tissues, and its viability or apoptosis after treatment with ddp was determined with mtt or annexin v/pi assays, respectively. |
2015-06-24 |
2023-08-13 |
Not clear |
| Wen-Xiao Xu, Yang Liu, Sheng-Zhi Liu, Yu Zhang, Guo-Fen Qiao, Jinglong Ya. Arsenic trioxide exerts a double effect on osteoblast growth in vitro. Environmental toxicology and pharmacology. vol 38. issue 2. 2015-06-23. PMID:25128771. |
cell survives, apoptosis, collagen, and molecular targets were identified by multiple detecting techniques, including mtt assay, electron microscopy, collagen detecting kit, tunel kit, and western blot in hfob1.19 human osteoblasts cell line. |
2015-06-23 |
2023-08-13 |
human |
| C X Huang, J N Zhao, W H Zou, J J Li, P C Wang, C H Liu, Y B Wan. Reduction of galectin-3 expression reduces pituitary tumor cell progression. Genetics and molecular research : GMR. vol 13. issue 3. 2015-06-22. PMID:25177969. |
we used rna interference to depress gal-3 gene expression; mtt and flow cytometry were applied to detect changes in cell proliferation and apoptosis levels in pituitary tumor cells. |
2015-06-22 |
2023-08-13 |
Not clear |
| Fen Zhou, Yikui Zhang, Ding Chen, Zhitao Su, Ling Jin, Lei Wang, Zhixiang Hu, Zhisheng Ke, Zongming Son. Potential role of Cyr61 induced degeneration of human Müller cells in diabetic retinopathy. PloS one. vol 9. issue 10. 2015-06-22. PMID:25329584. |
effects of cyr61 on müller cells viability, migration and apoptosis were observed by mtt assay, transwell assay, and tunel assay. |
2015-06-22 |
2023-08-13 |
human |
| Hafiz Muhammad Ali, Giorgia Urbinati, Hubert Chapuis, Didier Desmaele, Jean-Rémi Bertrand, Patrick Couvreur, Liliane Massaad-Massad. Effects of siRNA on RET/PTC3 junction oncogene in papillary thyroid carcinoma: from molecular and cellular studies to preclinical investigations. PloS one. vol 9. issue 4. 2015-06-19. PMID:24759995. |
in vitro sirna ret/ptc3 showed significant (p<0.001) inhibitory effects on rp3 cell viability (mtt assay) and on invasion/migration (incucyte scratch test) with blockage of cell cycle at g0/g1 phase (flow cytometry) and induced apoptosis by caspase-3 and parp1 cleavage (wb). |
2015-06-19 |
2023-08-13 |
mouse |
| Wei Tan, Hong-Gang Yu, He-Sheng Lu. Inhibition of the p38 MAPK pathway sensitizes human gastric cells to doxorubicin treatment in vitro and in vivo. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25270341. |
the effect of doxorubicin on the growth and apoptosis of gastric cancer cells in the presence or absence of sb203580 was investigated by western blot analysis, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, hoechst staining, annexin v-fitc/propidium iodide staining followed by flow cytometry analysis, and the terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) assay. |
2015-06-19 |
2023-08-13 |
human |
| Dong Li, Li-Nan Zhao, Xiu-Lan Zheng, Ping Lin, Feng Lin, Yue Li, Hai-Feng Zou, Rong-Jun Cui, Hui Chen, Xiao-Guang Y. Sox2 is involved in paclitaxel resistance of the prostate cancer cell line PC-3 via the PI3K/Akt pathway. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25310235. |
in the present study, using mtt, clone formation, cell cycle and apoptosis assays, over-expression of sox2 was demonstrated to enhance the paclitaxel (pac) resistance of the pc-3 prostate cancer cell line, promoting cell proliferation and exhibiting an anti‑apoptotic effect. |
2015-06-19 |
2023-08-13 |
Not clear |
| Yan Jing Li, Peng Huang, Cai Ling Jiang, De Xin Jia, Xiao Xue Du, Jian Hua Zhou, Yu Han, Hong Sui, Xiao Li Wei, Lei Liu, Heng Heng Yuan, Ting Ting Zhang, Wen Jie Zhang, Rui Xie, Xiao Hui Lang, Li Ying Wang, Tao Liu, Yu Xian Bai, Ye Tia. Sonodynamically induced anti-tumor effect of 5-aminolevulinic acid on pancreatic cancer cells. Ultrasound in medicine & biology. vol 40. issue 11. 2015-06-18. PMID:25220273. |
cell viability was determined by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide) analysis; mitochondrial membrane potential was assessed using the fluorescent probe jc-1; apoptosis was evaluated by flow cytometry; cell morphology was investigated by scanning electron microscopy; apoptosis-related protein expression was analyzed by western blot assay. |
2015-06-18 |
2023-08-13 |
human |
| Gu Gong, Libang Yuan, Lin Cai, Maorong Ran, Yulan Zhang, Huaqu Gong, Xuemei Dai, Wei Wu, Hailong Don. Tetramethylpyrazine suppresses transient oxygen-glucose deprivation-induced connexin32 expression and cell apoptosis via the ERK1/2 and p38 MAPK pathway in cultured hippocampal neurons. PloS one. vol 9. issue 9. 2015-06-16. PMID:25237906. |
the effect of tmp on hippocampal neurons viability was detected by mtt assay, ldh release assay and apoptosis rate was measured by flow cytometry. |
2015-06-16 |
2023-08-13 |
Not clear |