| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yue-Jun Fu, Jie Zhao, Ai-Hua Liang, Feng-Yun H. AcMNPV-mediated expression of BmK IT promotes the apoptosis of Sf9 cells and replication of AcMNPV. Sheng li xue bao : [Acta physiologica Sinica]. vol 67. issue 3. 2015-09-10. PMID:26109303. |
spodopter frugiperda 9 (sf9) cells were infected with acmnpv and acmnpv-bmk it respectively for 24 h. results from the mtt assay, tunel assay, analysis of the expression level of apoptosis-related proteins (c-myc, cleaved-caspase3, bcl-2 and bax) of sf9 cells, the transcription level of key genes (38k, c42, p78, f) of acmnpv, and viral propagation assay demonstrated that acmnpv-mediated expression of bmk it promoted the apoptosis of sf9 cells and replication of acmnpv. |
2015-09-10 |
2023-08-13 |
Not clear |
| G G Sun, Y D Wang, Q Liu, W N H. Expression of Wip1 in kidney carcinoma and its correlation with tumor metastasis and clinical significance. Pathology oncology research : POR. vol 21. issue 1. 2015-09-09. PMID:24970693. |
mtt assay, cell apoptosis, cell migration and invasion were also conducted as to the influence of the down-regulated expression of wip1 that might be found on achn cells biological effect. |
2015-09-09 |
2023-08-13 |
Not clear |
| G G Sun, Y D Wang, Q Liu, W N H. Expression of Wip1 in kidney carcinoma and its correlation with tumor metastasis and clinical significance. Pathology oncology research : POR. vol 21. issue 1. 2015-09-09. PMID:24970693. |
mtt assay, cell apoptosis, cell cycles demonstrated that achn cell transfected wip1 sirna had a lower survival fraction, higher cell apoptosis, more percentage of the g0/g1 phases, significant decrease in migration and invasion, and higher p53 and p16 protein expression compared with achn cell untransfected wip1 sirna (p < 0.05). |
2015-09-09 |
2023-08-13 |
Not clear |
| Pei-Hua Li, Jin-Xia Wu, Jun-Nian Zheng, Dong-Sheng Pe. A sphingosine kinase-1 inhibitor, SKI-II, induces growth inhibition and apoptosis in human gastric cancer cells. Asian Pacific journal of cancer prevention : APJCP. vol 15. issue 23. 2015-09-09. PMID:25556479. |
after treatment with ski-ii, cell growth, cell cycle distribution, apoptosis, expression of sphk1, nf-κb, bcl-2, bax and p27 were assessed by mtt assay, flow cytometry, electron microscopy, immunocytochemistry and western-blot assay, respectively. |
2015-09-09 |
2023-08-13 |
human |
| H Wang, H M Zhang, H J Yin, L Q Zheng, M Q Wei, H Sha, Y X L. Combination of a novel photosensitizer DTPP with 650 nm laser results in efficient apoptosis and cytoskeleton collapse in breast cancer MCF-7 cells. Cell biochemistry and biophysics. vol 69. issue 3. 2015-09-03. PMID:24477573. |
the survival rates of mcf-7 cells were measured using a sensitive cell proliferation assay (mtt) to establish optimal semilethal dose and optimal time exposure, a further study of effects on cytoskeleton and apoptosis were also performed. |
2015-09-03 |
2023-08-12 |
Not clear |
| Qiruo Gao, Junhua Zhen. Adiponectin-induced antitumor activity on prostatic cancers through inhibiting proliferation. Cell biochemistry and biophysics. vol 70. issue 1. 2015-09-03. PMID:24793551. |
the proliferation rate of the pc-3 cells was measured using the mtt method, and apoptosis was examined by quantifying the dna fragmentation using an elisa assay. |
2015-09-03 |
2023-08-13 |
human |
| Farnoosh Saraee, Mohsen Sagha, Homa Mohseni Kouchesfehani, Alireza Abdanipour, Masoud Maleki, Mahin Nikougofta. Biological parameters influencing the human umbilical cord-derived mesenchymal stem cells' response to retinoic acid. BioFactors (Oxford, England). vol 40. issue 6. 2015-09-03. PMID:25408532. |
here, using mtt assay and eb/ao staining as well as tunel assay we show that ra in a concentration-dependent manner induces apoptosis through upregulating caspase expression and increasing bax/bcl2 ratio. |
2015-09-03 |
2023-08-13 |
human |
| Dengfeng Li, Wei Jian, Chuankui Wei, Hongming Song, Yifan Gu, Yi Luo, Lin Fan. Down-regulation of miR-181b promotes apoptosis by targeting CYLD in thyroid papillary cancer. International journal of clinical and experimental pathology. vol 7. issue 11. 2015-09-02. PMID:25550803. |
mtt assays, colony formation assays, apoptosis assays were used to explore the potential function of mir-181b inhibitor in tpc1 human thyroid papillary cancer cells. |
2015-09-02 |
2023-08-13 |
human |
| Zhitu Zhu, Hongzhi Sun, Guangyou Ma, Zhenghua Wang, Enze Li, Yangyang Liu, Yunpeng Li. Bufalin induces lung cancer cell apoptosis via the inhibition of PI3K/Akt pathway. International journal of molecular sciences. vol 13. issue 2. 2015-09-01. PMID:22408435. |
a549 cells were treated with bufalin, then the proliferation was detected by mtt assay and apoptosis was detected by flow cytometry analysis and giemsa staining. |
2015-09-01 |
2023-08-12 |
human |
| Xiao-fei Wang, Shu-zhen Che. [Expression and antitumor activity of fusion protein RGD-TRAIL in Pichia pastoris]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 50. issue 5. 2015-09-01. PMID:26234135. |
mtt assay, elisa, scratch wound healing, transwell migration assay and hoechst 33342 staining were performed to detect the effects of rgd-trail on proliferation, binding activity, migration and apoptosis. |
2015-09-01 |
2023-08-13 |
Not clear |
| Jun Xia, Youjian Li, Qingling Yang, Chuanzhong Mei, Zhiwen Chen, Bin Bao, Aamir Ahmad, Lucio Miele, Fazlul H Sarkar, Zhiwei Wan. Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer. International journal of molecular sciences. vol 13. issue 8. 2015-08-31. PMID:22949821. |
for mechanistic studies, we used multiple cellular and molecular approaches such as mtt assay, apoptosis elisa assay, gene transfection, rt-pcr, western blotting, and invasion assays. |
2015-08-31 |
2023-08-12 |
human |
| Ju-Fang Liu, Yuan-Li Huang, Wei-Hung Yang, Chih-Shiang Chang, Chih-Hsin Tan. 1-benzyl-2-phenylbenzimidazole (BPB), a benzimidazole derivative, induces cell apoptosis in human chondrosarcoma through intrinsic and extrinsic pathways. International journal of molecular sciences. vol 13. issue 12. 2015-08-31. PMID:23211670. |
bpb-mediated apoptosis was assessed by the mtt assay and flow cytometry analysis. |
2015-08-31 |
2023-08-12 |
human |
| Xingfu Bao, Xiaoxi Wei, Yuzhuo Wang, Huan Jiang, Dongsheng Yu, Min H. Effect of silica-based nanomaterials and their derivate with PEGylation on cementoblasts. Annals of biomedical engineering. vol 42. issue 8. 2015-08-31. PMID:24752634. |
methods including mtt assay, apoptosis, ldh, as well as ros analysis were introduced in our study. |
2015-08-31 |
2023-08-13 |
Not clear |
| Javad Verdi, Shiva Sharif, Hamid Reza Banafshe, Alireza Shoae-Hassan. Sertraline increases the survival of retinoic acid induced neuronal cells but not glial cells from human mesenchymal stem cells. Cell biology international. vol 38. issue 8. 2015-08-28. PMID:24715678. |
the survival of differentiated cells was measured by mtt assay and the frequency of apoptosis, demonstrated by caspase-3-like activity. |
2015-08-28 |
2023-08-13 |
human |
| Takayuki Nagano, Shinya H Kimura, Motohiko Takemur. Prostaglandin E2 induces apoptosis in cultured rat microglia. Brain research. vol 1568. 2015-08-21. PMID:24845544. |
pge2 decreased 3-(4,5-dimethylthiazol-2-thiazolyl)-2,5-diphenyltetrazolium bromide (mtt) reduction and increased lactate dehydrogenase release, deoxyribonucleic acid fragmentation, and poly(adp-ribose) polymerase cleavage after 24h incubation, suggesting that pge2 induces apoptosis in these cells. |
2015-08-21 |
2023-08-13 |
rat |
| Dong Hoon Kwak, Ji-Hye Park, Hak-Seung Lee, Ji-Sook Moon, Seoul Le. Aristolochic Acid I induces ovarian toxicity by inhibition of akt phosphorylation. Chemical research in toxicology. vol 27. issue 12. 2015-08-21. PMID:25406029. |
we used chinese hamster ovary-k1 (cho-k1) cells and an aai injection mouse model: mtt assay was used to assess aa toxicity to cells; ovary size and weight were measured to determine the toxicity of aa to mouse ovary; western blot was used to assess apoptosis; tunel assay was used to evaluate apoptotic cell death; and immunohistochemistry was used to examine the local expression of apoptotic proteins in ovary tissue. |
2015-08-21 |
2023-08-13 |
mouse |
| Thirunavukkarasu Ashokkumar, Durai Prabhu, Ravi Geetha, Kasivelu Govindaraju, Ramar Manikandan, Chinnasamy Arulvasu, Ganesan Singaravel. Apoptosis in liver cancer (HepG2) cells induced by functionalized gold nanoparticles. Colloids and surfaces. B, Biointerfaces. vol 123. 2015-08-19. PMID:25444656. |
anticancer activity has been studied using liver cancer cells and cytotoxic mechanism has been evaluated using mtt, annexin-v/pi double-staining assay, cell cycle, comet assay and flow cytometric analysis for apoptosis. |
2015-08-19 |
2023-08-13 |
Not clear |
| Hu Song, Wei Xu, Jun Song, Yong Liang, Wei Fu, Xiao-Cheng Zhu, Chao Li, Jun-Sheng Peng, Jun-Nian Zhen. Overexpression of Lin28 inhibits the proliferation, migration and cell cycle progression and induces apoptosis of BGC-823 gastric cancer cells. Oncology reports. vol 33. issue 2. 2015-08-11. PMID:25515921. |
cell proliferation and migration capabilities were investigated by mtt and transwell assays, while cell cycle distribution and the apoptosis rate were detected using flow cytometry. |
2015-08-11 |
2023-08-13 |
human |
| Chang Su, Hongdan Li, Yijie Shi, Guan Wang, Liwei Liu, Liang Zhao, Rongjian S. Carboxymethyl-β-cyclodextrin conjugated nanoparticles facilitate therapy for folate receptor-positive tumor with the mediation of folic acid. International journal of pharmaceutics. vol 474. issue 1-2. 2015-08-07. PMID:25149123. |
the results showed that mtt and cell apoptosis demonstrated that fa-decorated nps exhibit stronger inhibition rate and induce obvious apoptosis in fr positive hela cells as compared to free drug and fa undecorated nps. |
2015-08-07 |
2023-08-13 |
Not clear |
| Luca Gallelli, Daniela Falcone, Monica Scaramuzzino, Girolamo Pelaia, Bruno D'Agostino, Maria Mesuraca, Rosa Terracciano, Giuseppe Spaziano, Rosario Maselli, Michele Navarra, Rocco Savin. Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide. BMC pharmacology & toxicology. vol 15. 2015-08-04. PMID:25432084. |
cell counting was performed after trypan blue staining, cell proliferation was assessed using mtt assay, and apoptosis was evaluated through caspase-3 activation and tunel assay. |
2015-08-04 |
2023-08-13 |
human |