| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aijun Zhu, Yu Ren, Ning Wang, Qiuyue Jin, Dongchang Zhang, Guangxiao Yang, Quanying Wan. Adeno-associated virus mediated gene transfer of Shepherdin inhibits gallbladder carcinoma growth in vitro and in vivo. Gene. vol 572. issue 1. 2015-12-04. PMID:26143116. |
mtt assay and flow cytometric analysis demonstrated that raav containing shepherdin gene could significantly inhibit the growth of gbc and this effect was closely associated with apoptosis. |
2015-12-04 |
2023-08-13 |
Not clear |
| Bao-Yi Zhang, Yan-Ming Wang, Hai Gong, Hui Zhao, Xiao-Yan Lv, Guang-Hui Yuan, Shao-Rong Ha. Isorhamnetin flavonoid synergistically enhances the anticancer activity and apoptosis induction by cis-platin and carboplatin in non-small cell lung carcinoma (NSCLC). International journal of clinical and experimental pathology. vol 8. issue 1. 2015-12-03. PMID:25755690. |
in order to assess the anticancer enhancing effect of isorhamnetin on cisplatin and carboplatin, a-549 cells were treated with isorhamnetin, cisplatin, carboplatin and their combinations and cell viability, cell apoptosis, cell cycle arrest as well as loss of mitochondrial membrane potential were evaluated by mtt assay, flow cytometry, confocal microscopy and fluorescence microscopy. |
2015-12-03 |
2023-08-13 |
Not clear |
| Qiong-Yu Lan, Que-Ling Liu, Jing Cai, An-Wen Li. 3-cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-one (CHP) inhibits human ovarian cell proliferation by inducing apoptosis. International journal of clinical and experimental pathology. vol 8. issue 1. 2015-12-03. PMID:25755702. |
the data from mtt assay revealed a significant inhibitory effect on cell viability at 30 (87%) and 50 μm (74%) concentration of chp in ovcar-3 and ovcar-420 cells, respectively after 72 h. apoptosis analysis using annexin v/pi double staining followed by flow cytometry showed 59 and 52% binding to annexin v-fitc in ovcar-3 and ovcar-420 cells respectively. |
2015-12-03 |
2023-08-13 |
human |
| Salvatore Giunta, Alessandro Castorina, Rubina Marzagalli, Marta Anna Szychlinska, Karin Pichler, Ali Mobasheri, Giuseppe Musumec. Ameliorative effects of PACAP against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis. International journal of molecular sciences. vol 16. issue 3. 2015-12-02. PMID:25782157. |
in vitro, pacap prevented il-1β-induced chondrocyte apoptosis, as determined by mtt assay; hoechst staining and western blots of apoptotic-related proteins. |
2015-12-02 |
2023-08-13 |
rat |
| Zhaojun Wan, Huazheng Pan, Shihai Liu, Jingjuan Zhu, Weiwei Qi, Kai Fu, Teng Zhao, Jun Lian. Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-κB pathway. Oncology reports. vol 33. issue 3. 2015-12-01. PMID:25607597. |
hcc cell viability and apoptosis were assessed using an mtt assay and the hoechst test. |
2015-12-01 |
2023-08-13 |
Not clear |
| Zhenhua He, Jingmin Yuan, Ping Qi, Lixiu Zhang, Zhiping Wan. Atorvastatin induces autophagic cell death in prostate cancer cells in vitro. Molecular medicine reports. vol 11. issue 6. 2015-12-01. PMID:25672364. |
apoptosis was examined by terminal deoxynucleotidyl transferase dutp nick end labeling assay and an mtt assay was used to evaluate cell viability. |
2015-12-01 |
2023-08-13 |
Not clear |
| Xinting Pan, Qingyun Zhu, Yunbo Sun, Liandi Li, Yunpeng Zhu, Zhihui Zhao, Jianxin Zuo, Wei Fang, Kun L. PLGA/poloxamer nanoparticles loaded with EPAS1 siRNA for the treatment of pancreatic cancer in vitro and in vivo. International journal of molecular medicine. vol 35. issue 4. 2015-12-01. PMID:25672594. |
mtt and apoptosis assays were then performed. |
2015-12-01 |
2023-08-13 |
mouse |
| Leisheng Wang, Pengzhou Gai, Renguo Xu, Yanpin Zheng, Shiqiao Lv, Yu Li, Shaoxian Li. Shikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathway. International journal of clinical and experimental pathology. vol 8. issue 1. 2015-12-01. PMID:25755716. |
the mtt assay and ldh cell death assay were used to determine the cell viability and chondrocyte apoptosis was detected by annexin-v/pi staining and nucleosomal degradation. |
2015-12-01 |
2023-08-13 |
rat |
| Shuguo Zheng, Mengqiu Zhao, Younan Ren, Yuanjie Wu, Jieren Yan. Sesamin suppresses STZ induced INS-1 cell apoptosis through inhibition of NF-κB activation and regulation of Bcl-2 family protein expression. European journal of pharmacology. vol 750. 2015-11-24. PMID:25637086. |
sesamin effectively improved stz induced cell damage as determined by mtt [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide] assay and insulin secretion capacity, and suppressed stz induced cell apoptosis as evaluated by flow cytometry using annexin v and propidium iodide double staining. |
2015-11-24 |
2023-08-13 |
Not clear |
| Bilal Çiğ, Mustafa Nazıroğl. Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells. Biochimica et biophysica acta. vol 1848. issue 10 Pt B. 2015-11-24. PMID:25703814. |
the cytosolic ros production, ca2+ concentrations, apoptosis, caspase-3 and caspase-9 values were higher in groups b, c and d than in a group at 0 cm, 1 cm and 5 cm distances although cell viability (mtt) values were increased by the distances. |
2015-11-24 |
2023-08-13 |
human |
| Cong Yu, Shang Cui, Chen Zong, Weina Gao, Tongfu Xu, Peng Gao, Jicui Chen, Dandan Qin, Qingbo Guan, Yuantao Liu, Yuchang Fu, Xia Li, Xiangdong Wan. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis. The Journal of biological chemistry. vol 290. issue 34. 2015-11-23. PMID:26157144. |
nr4a1 overexpression in min6 cells conferred resistance to cell loss induced by tg or pa, as assessed by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, and tunel assays indicated that nr4a1 overexpression also protected against er stress-induced apoptosis. |
2015-11-23 |
2023-08-13 |
mouse |
| Fengli Zhang, Meiheriguli Mijiti, Wei Ding, Jiale Song, Ying Yin, Wei Sun, Zhiyong L. (+)‑Terrein inhibits human hepatoma Bel‑7402 proliferation through cell cycle arrest. Oncology reports. vol 33. issue 3. 2015-11-17. PMID:25592371. |
in this study, (+)‑terrein isolated from the marine sponge‑derived aspergillus terreus pf‑26 against cell growth, apoptosis and cell cycle were assessed by mtt and flow cytometry. |
2015-11-17 |
2023-08-13 |
human |
| Ruitao Zhang, Huirong Shi, Fang Ren, Huina Liu, Minghui Zhang, Youxing Deng, Xia L. Misregulation of polo-like protein kinase 1, P53 and P21WAF1 in epithelial ovarian cancer suggests poor prognosis. Oncology reports. vol 33. issue 3. 2015-11-17. PMID:25592872. |
cell proliferation, apoptosis and invasion were examined by mtt assay, flow cytometry and matrigel assay, respectively. |
2015-11-17 |
2023-08-13 |
human |
| Joanna Ho, Yanan Du, Oscar Gee-Wan Wong, Michelle K Y Siu, Karen K L Chan, Annie N Y Cheun. Downregulation of the gli transcription factors regulator Kif7 facilitates cell survival and migration of choriocarcinoma cells. PloS one. vol 9. issue 9. 2015-11-16. PMID:25265279. |
ectopic expression of kif7 in two choriocarcinoma cell lines jar and jeg-3 led to a decrease in cell growth and increase in apoptosis demonstrated by mtt and tunel assays, respectively. |
2015-11-16 |
2023-08-13 |
human |
| Guang-Zhou An, Hui Xu, Yan Zhou, Le Du, Xia Miao, Da-Peng Jiang, Kang-Chu Li, Guo-Zhen Guo, Chen Zhang, Gui-Rong Din. Effects of long-term 50Hz power-line frequency electromagnetic field on cell behavior in Balb/c 3T3 cells. PloS one. vol 10. issue 2. 2015-11-16. PMID:25695503. |
cell morphology was observed under invert microscope and giemsa staining, cell viability was detected by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (mtt) assay, cell cycle and apoptosis was examined by flow cytometry, the protein level of proliferating cell nuclear antigen (pcna) and cyclind1 was detected by western blot, cell transformation was examined by soft agar clone assay and plate clone forming test, and cell migration ability was observed by scratch adhesion test. |
2015-11-16 |
2023-08-13 |
human |
| Jung Yoon Yang, Min Young Park, Sam Young Park, Hong Il Yoo, Min Seok Kim, Jae Hyung Kim, Won Jae Kim, Ji Yeon Jun. Nitric Oxide-Induced Autophagy in MC3T3-E1 Cells is Associated with Cytoprotection via AMPK Activation. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 19. issue 6. 2015-11-11. PMID:26557017. |
the effect of sodium nitroprusside (snp), an no donor, on the cytotoxicity of the mc3t3-e1 cells was determined by mtt assay and expression of apoptosis or autophagy associated molecules was evaluated by western blot analysis. |
2015-11-11 |
2023-08-13 |
Not clear |
| Lifeng Liu, Yuanjian Song, Limin Ma, Lixin Zang, Lili Tao, Zhiguo Zhang, Jiwu Ha. Growth inhibition effect of HMME-mediated PDT on hepatocellular carcinoma HepG2 cells. Lasers in medical science. vol 29. issue 5. 2015-11-10. PMID:24798494. |
the viability of the treated cells was determined using the mtt assay, and cell apoptosis was evaluated using flow cytometry. |
2015-11-10 |
2023-08-13 |
Not clear |
| Xiao-jing Dai, Na Li, Le Yu, Zi-yang Chen, Rong Hua, Xia Qin, Yong-Mei Zhan. Activation of BV2 microglia by lipopolysaccharide triggers an inflammatory reaction in PC12 cell apoptosis through a toll-like receptor 4-dependent pathway. Cell stress & chaperones. vol 20. issue 2. 2015-11-10. PMID:25387796. |
cell viability was determined by mtt assay and cell apoptosis was tested by flow cytometry. |
2015-11-10 |
2023-08-13 |
Not clear |
| Izaskun Buendia, Javier Egea, Esther Parada, Elisa Navarro, Rafael León, María Isabel Rodríguez-Franco, Manuela G Lópe. The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction. ACS chemical neuroscience. vol 6. issue 2. 2015-11-10. PMID:25393881. |
in this toxicity model, ith91/iqm157 (1-1000 nm) reduced cell death measured as mtt reduction; at 100 nm, it prevented apoptosis, retraction of prolongations, and aβ aggregates. |
2015-11-10 |
2023-08-13 |
human |
| Chi Pan, Yiwang Hu, Jun Li, Zhaoyi Wang, Jianjin Huang, Suzhan Zhang, Ling Din. Estrogen receptor-α36 is involved in pterostilbene-induced apoptosis and anti-proliferation in in vitro and in vivo breast cancer. PloS one. vol 9. issue 8. 2015-11-09. PMID:25127034. |
methyl-thiazolyl-tetrazolium (mtt) assay, apoptosis analysis, and an orthotropic xenograft mouse model were used to examine the effects of pterostilbene on breast cancer cells. |
2015-11-09 |
2023-08-13 |
mouse |