| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas Nury, Amira Zarrouk, John J Mackrill, Mohammad Samadi, Philippe Durand, Jean-Marc Riedinger, Margaux Doria, Anne Vejux, Emeric Limagne, Dominique Delmas, Michel Prost, Thibault Moreau, Mohamed Hammami, Régis Delage-Mourroux, Nora M O'Brien, Gérard Lizar. Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3). Steroids. vol 99. issue Pt B. 2016-03-07. PMID:25683890. |
in these cells, 7kc as well as 7β-ohc and 24s-ohc induce a decrease of cell proliferation evaluated by phase contrast microscopy, an alteration of mitochondrial activity quantified with the mtt test, an overproduction of reactive oxygen species revealed by staining with dihydroethidium and dihydrorhodamine 123, caspase-3 activation, parp degradation, reduced expression of bcl-2, and condensation and/or fragmentation of the nuclei which are typical criteria of oxidative stress and apoptosis. |
2016-03-07 |
2023-08-13 |
Not clear |
| Song-Tao Xu, Chun Guo, Xiang Ding, Wen-Juan Fan, Fu-Hua Zhang, Wan-Ling Xu, Yong-Chao M. Role of osteopontin in the regulation of human bladder cancer proliferation and migration in T24 cells. Molecular medicine reports. vol 11. issue 5. 2016-03-04. PMID:25591934. |
in addition, the cell cycle progression, apoptosis and proliferation were investigated using by flow cytometric analysis and mtt assay. |
2016-03-04 |
2023-08-13 |
human |
| Jianheng Zhou, Jiumao Lin, Liya Liu, Yuqing Zheng, Zhenfeng Hon. Qianliening capsules influence the apoptosis of benign prostatic hyperplasia epithelial-1 cells by regulating the extracellular matrix. Molecular medicine reports. vol 11. issue 5. 2016-03-04. PMID:25592406. |
the cell morphology and viability were determined using light microscopy and an mtt assay and cell apoptosis was detected by annexin v staining. |
2016-03-04 |
2023-08-13 |
Not clear |
| Xiyu Liu, Song Yan, Changyan Pei, Youbin Cu. Decreased microRNA-132 and its function in human non-small cell lung cancer. Molecular medicine reports. vol 11. issue 5. 2016-03-04. PMID:25607827. |
an mtt assay, flow cytometry, transwell invasion assays and scratch migration assays were conducted in order to examine the proliferation, apoptosis, invasion and migration of nsclc cells that had been transfected with mir‑132 mimics or inhibitors. |
2016-03-04 |
2023-08-13 |
human |
| Sonia Soloneski, Maciej Kujawski, Anna Scuto, Marcelo L Larramend. Carbamates: A study on genotoxic, cytotoxic, and apoptotic effects induced in Chinese hamster ovary (CHO-K1) cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 29. issue 5. 2016-03-03. PMID:25820133. |
whereas the cytokinesis-blocked micronucleus cytome assay was employed to test for genotoxicity, mtt, neutral red (nr), and apoptosis evaluation were used as tests for estimating cell viability and succinic dehydrogenase activity, respectively. |
2016-03-03 |
2023-08-13 |
human |
| Mingqun Li, Li Hon. Pseudolaric acid B exerts antitumor activity via suppression of the Akt signaling pathway in HeLa cervical cancer cells. Molecular medicine reports. vol 12. issue 2. 2016-03-03. PMID:25891953. |
in the present study, the effects of pab on the viability and apoptosis of hela cells were investigated by mtt assay, flow cytometric analysis of annexin v-fluorescein isothiocyanate/propidium iodide staining, rhodamine 123 staining and western blot analysis. |
2016-03-03 |
2023-08-13 |
human |
| Xin-Hong Wang, Ming-Na Liu, Ping Huang, Jun Xu, Ai-Yun Liu, Jing Chen, Cheng-Qian Lv, Rui-Ling X. Simultaneous silencing of β-catenin and signal transducer and activator of transcription 3 synergistically induces apoptosis and inhibits cell proliferation in HepG2 liver cancer cells. Molecular medicine reports. vol 12. issue 2. 2016-03-01. PMID:25845340. |
the cell growth was assessed using an mtt assay and the levels of cell apoptosis were detected using flow cytometry. |
2016-03-01 |
2023-08-13 |
Not clear |
| Bin Wang, JiaQing Fang, Lei Qu, Zhongwei Cao, JianGuo Zhou, Biao Den. Upregulated TRIO expression correlates with a malignant phenotype in human hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 9. 2016-03-01. PMID:25851347. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay was employed to measure cell proliferation, and apoptosis assay was analyzed by flow cytometry, respectively. |
2016-03-01 |
2023-08-13 |
human |
| Jianhua Yang, Yao Yan, Huibin Liu, Jianhua Wang, Junping H. Protective effects of acteoside against X‑ray‑induced damage in human skin fibroblasts. Molecular medicine reports. vol 12. issue 2. 2016-03-01. PMID:25892089. |
cell viability, apoptosis and intracellular alteration of redox were monitored by mtt and flow cytometry. |
2016-03-01 |
2023-08-13 |
human |
| Jin-Ling Yi, Song Shi, Yan-Li Shen, Ling Wang, Hai-Yan Chen, Jun Zhu, Yan Din. Myricetin and methyl eugenol combination enhances the anticancer activity, cell cycle arrest and apoptosis induction of cis-platin against HeLa cervical cancer cell lines. International journal of clinical and experimental pathology. vol 8. issue 2. 2016-03-01. PMID:25972998. |
to demonstrate whether myr and meg enhance the anticancer activity of cp against cervical cancer cells, we treated hela cells with myr and meg alone or in combination with cisplatin and evaluated cell growth and apoptosis using mtt (3 (4, 5 dimethyl thiazol 2yl) 2, 5 diphenyltetrazolium bromide) assay, ldh release assay, flow cytometry and fluorescence microscopy. |
2016-03-01 |
2023-08-13 |
human |
| Yu-Rong Zhao, Wei Qu, Wen-Yuan Liu, Hao Hong, Feng Feng, Han Chen, Ning Xi. YGS40, an active fraction of Yi-Gan San, reduces hydrogen peroxide-induced apoptosis in PC12 cells. Chinese journal of natural medicines. vol 13. issue 6. 2016-03-01. PMID:26073340. |
cytotoxicity was determined by mtt (3, (4, 5-dimethylthiazole-2-yl) 2, 5-diphenyl-tetrazolium bromide) and lactate dehydrogenase (ldh) release assays; apoptosis was detected by annexin v/propidium iodide coupled staining and by determining caspase-3 activity and bax and bcl-2 protein levels. |
2016-03-01 |
2023-08-13 |
Not clear |
| Silvia Lorena Montes-Fonseca, Blanca Sánchez-Ramírez, Antonia Luna-Velasco, Carlos Arzate-Quintana, Macrina Beatriz Silva-Cazares, Carmen González Horta, Erasmo Orrantia-Borund. Cytotoxicity of protein-carbon nanotubes on J774 macrophages is a functionalization grade-dependent effect. BioMed research international. vol 2015. 2016-03-01. PMID:26075262. |
in vitro cytotoxicity was evaluated by mtt, apoptosis, and morphological assays. |
2016-03-01 |
2023-08-13 |
Not clear |
| Agnieszka Sliwinska, Aneta Rogalska, Agnieszka Marczak, Jacek Kasznicki, Jozef Drzewosk. Metformin, but not sitagliptin, enhances WP 631-induced apoptotic HepG2 cell death. Toxicology in vitro : an international journal published in association with BIBRA. vol 29. issue 5. 2016-02-29. PMID:25959860. |
both mtt assay and flow cytometry analysis showed that wp 631 reduced the growth of hepg2 cells by apoptosis induction, accompanied by elevated nf-κb and p53 levels. |
2016-02-29 |
2023-08-13 |
human |
| Jian Chen, Xinge Zhao, Xin Li, Yiying W. Calycosin induces apoptosis by the regulation of ERβ/miR-17 signaling pathway in human colorectal cancer cells. Food & function. vol 6. issue 9. 2016-02-29. PMID:26215320. |
cell proliferation, apoptosis and invasiveness were measured by mtt assay, flow cytometry and transwell invasion assay, respectively. |
2016-02-29 |
2023-08-13 |
human |
| G G Sun, J Zhang, X B Ma, Y D Wang, Y J Cheng, W N H. Overexpression of Wild-Type p53-Induced Phosphatase 1 Confers Poor Prognosis of Patients with Nasopharyngeal Carcinoma. Pathology oncology research : POR. vol 21. issue 2. 2016-02-22. PMID:25060857. |
mtt assay, cell apoptosis, migration and invasion were also conducted as to the influence of the down-regulated expression of wip1 that might be found on cne2 cells biological effect. |
2016-02-22 |
2023-08-13 |
Not clear |
| G G Sun, J Zhang, X B Ma, Y D Wang, Y J Cheng, W N H. Overexpression of Wild-Type p53-Induced Phosphatase 1 Confers Poor Prognosis of Patients with Nasopharyngeal Carcinoma. Pathology oncology research : POR. vol 21. issue 2. 2016-02-22. PMID:25060857. |
mtt assay, cell apoptosis, cell cycles demonstrated that cne2 cell transfected wip1 sirna had a lower survival fraction, higher cell apoptosis, more percentage of the g0/g1 phases, significant decrease in migration and invasion, and higher p53 and p16 protein expression compared with cne2 cell untransfected wip1 sirna (p < 0.05). |
2016-02-22 |
2023-08-13 |
Not clear |
| Fei Yu, Kai Li, Suning Chen, Yunpeng Liu, Yan L. Pseudolaric acid B circumvents multidrug resistance phenotype in human gastric cancer SGC7901/ADR cells by downregulating Cox-2 and P-gp expression. Cell biochemistry and biophysics. vol 71. issue 1. 2016-02-22. PMID:25077681. |
the effects of pseudolaric acid b and chemotherapeutic agents on cell proliferation and apoptosis were assessed using the mtt assay and flow cytometry, respectively. |
2016-02-22 |
2023-08-13 |
human |
| Jun-Ru Liu, Wen-Juan Wu, Shu-Xia Liu, Lian-Fu Zuo, Yuan Wang, Jian-Zhu Yang, Yue-Min Na. Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway. Pathology, research and practice. vol 211. issue 6. 2016-02-22. PMID:25724470. |
cell proliferation was evaluated using the mtt assay, and apoptosis was investigated. |
2016-02-22 |
2023-08-13 |
mouse |
| Yu Bai, Maling Gou, Tao Yi, Li Yang, Lili Liu, Xiaojuan Lin, Dan Su, Yuquan Wei, Xia Zha. Efficient Inhibition of Ovarian Cancer by Gelonin Toxin Gene Delivered by Biodegradable Cationic Heparin-polyethyleneimine Nanogels. International journal of medical sciences. vol 12. issue 5. 2016-02-17. PMID:26005374. |
cell viability and apoptosis were examined using an mtt assay and flow cytometric analysis. |
2016-02-17 |
2023-08-13 |
mouse |
| Bin Song, Ying Shu, Tianlei Cui, Ping F. Allicin inhibits human renal clear cell carcinoma progression via suppressing HIF pathway. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26884975. |
mtt assay and flow cytometry (fcm) were used to analyze cell viability and apoptosis. |
2016-02-17 |
2023-08-13 |
human |