| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aysun Adan, Yusuf Bara. The pleiotropic effects of fisetin and hesperetin on human acute promyelocytic leukemia cells are mediated through apoptosis, cell cycle arrest, and alterations in signaling networks. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 11. 2016-03-29. PMID:26081618. |
the viability of hl60 cells was evaluated using the mtt assay, apoptosis by annexin v/propidium iodide (pi) staining and cell cycle distribution using flow cytometry, and changes in caspase-3 enzyme activity and mitochondrial transmembrane potential. |
2016-03-29 |
2023-08-13 |
human |
| Sung-Moo Kim, Eun Young Oh, Jong Hyun Lee, Dongwoo Nam, Seok Geun Lee, Junhee Lee, Sung-Hoon Kim, Bum Sang Shim, Kwang Seok Ah. Brassinin Combined with Capsaicin Enhances Apoptotic and Anti-metastatic Effects in PC-3 Human Prostate Cancer Cells. Phytotherapy research : PTR. vol 29. issue 11. 2016-03-29. PMID:26426257. |
after treatment with bsn and cap at various concentrations, the synergistic cytotoxic effect of pc-3 cells was analyzed by mtt method, proliferation, apoptosis, mitochondrial membrane potential, colony formation, and western blotting. |
2016-03-29 |
2023-08-13 |
human |
| Jian-Xin Xu, Hai-Ping Song, Qing-Xia Bu, De-Peng Feng, Xiao-Fan Xu, Qian-Ru Sun, Xue-Li L. Isoflavone Attenuates the Caspase-1 and Caspase-3 Level in Cell Model of Parkinsonism. Behavioural neurology. vol 2015. 2016-03-25. PMID:26161002. |
cell viability was measured by mtt methods; the content of tyrosine hydroxylase was measured by immunocytochemistry method of avidinbiotin peroxidase complex; apoptosis ratio was measured by flow cytometry. |
2016-03-25 |
2023-08-13 |
human |
| Mohamed Alyane, Gillian Barratt, Mesbah Lahoue. Remote loading of doxorubicin into liposomes by transmembrane pH gradient to reduce toxicity toward H9c2 cells. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 24. issue 2. 2016-03-25. PMID:27013909. |
mtt assay and measurement of ldh release suggest that necrosis is the form of cellular death predominates in h9c2 cells exposed to high doses of dox, while for weak doses apoptosis could be the predominate form. |
2016-03-25 |
2023-08-13 |
Not clear |
| Ming Qi, Dongmei Liu, Shuhong Zhang, Peixin Hu, Tan San. Inhibition of S-phase kinase-associated protein 2-mediated p27 degradation suppresses tumorigenesis and the progression of hepatocellular carcinoma. Molecular medicine reports. vol 11. issue 5. 2016-03-24. PMID:25572801. |
the results from annexin v‑propidium iodide staining and mtt assays indicated that interference of skp2 significantly induced apoptosis and inhibited the proliferation of ssmc‑7721 cells. |
2016-03-24 |
2023-08-13 |
Not clear |
| Xikai Wang, Yanqiu Zhang, Yanyun Fu, Juan Zhang, Lihong Yin, Yuepu Pu, Geyu Lian. MicroRNA-125b may function as an oncogene in lung cancer cells. Molecular medicine reports. vol 11. issue 5. 2016-03-24. PMID:25573191. |
mtt, flow cytometry and transwell assays were also used to examine the effect of downregulated mir‑125b on the proliferation, apoptosis, invasive ability and cell cycle of 95d cells. |
2016-03-24 |
2023-08-13 |
human |
| Yi Liao, Qingli Xu, Jian Zhang, Jialing Niu, Guangyin Yuan, Yao Jiang, Yaohua He, Xinling Wan. Cellular response of chondrocytes to magnesium alloys for orthopedic applications. International journal of molecular medicine. vol 36. issue 1. 2016-03-24. PMID:25975216. |
the results of indirect cell cytotoxicity and proliferation assays, as well as those of apoptosis assay, glycosaminoglycan (gag) quantification, assessment of collagen Ⅱ (col Ⅱ) levels and rt-qpcr revealed a similar a trend as was observed with mtt assay. |
2016-03-24 |
2023-08-13 |
rabbit |
| Ning Gao, Huimin He, Li Xiao, Xiaojie Gao, Hongyan Shi, Qiong Wu, Nan Xu, Yuqing Lei, Xigui Song, Yingchun Ho. The effects of focal adhesion kinase on the motility, proliferation and apoptosis of Caco2 and SMMC-7721 cells. Medical oncology (Northwood, London, England). vol 32. issue 4. 2016-03-22. PMID:25790781. |
then, the proliferation, motility and apoptosis of both types of cells were detected using mtt assay, wound healing/transwell assay and nuclear staining assay. |
2016-03-22 |
2023-08-13 |
Not clear |
| Yu Gan, Jing Tan, Jianfu Yang, Yihong Zhou, Yingbo Dai, Leye He, Kun Yao, Yuxin Tan. Knockdown of HMGN5 suppresses the viability and invasion of human urothelial bladder cancer 5637 cells in vitro and in vivo. Medical oncology (Northwood, London, England). vol 32. issue 4. 2016-03-22. PMID:25796505. |
then cell viability, apoptosis and cell cycle distribution, invasion were detected by mtt assay, flow cytometry and transwell assay, respectively. |
2016-03-22 |
2023-08-13 |
mouse |
| Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wan. GDC-0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway. International journal of oncology. vol 46. issue 4. 2016-03-21. PMID:25651778. |
the viability of saos2 cells was determined by mtt assay, the migration of saos2 cells was analyzed by chamber migration assay kit, and the saos2 cell apoptosis was determined by fluorescence-activated cell sorting (facs) and nuclear staining. |
2016-03-21 |
2023-08-13 |
human |
| Chunlin Jiang, Jianting Long, Baoxian Liu, Xiaoyan Xie, Ming Kuan. Mcl-1 Is a Novel Target of miR-26b That Is Associated with the Apoptosis Induced by TRAIL in HCC Cells. BioMed research international. vol 2015. 2016-03-18. PMID:26078955. |
mtt and flow cytometry were employed to detect the cell viability and apoptosis. |
2016-03-18 |
2023-08-13 |
Not clear |
| Haijiao Lu, Zhuang Yu, Shihai Liu, Lianhua Cui, Xiaozheng Chen, Ruyong Ya. CUGBP1 promotes cell proliferation and suppresses apoptosis via down-regulating C/EBPα in human non-small cell lung cancers. Medical oncology (Northwood, London, England). vol 32. issue 3. 2016-03-17. PMID:25701464. |
the effect of depletion of cugbp1 was evaluated by mtt assay and annexin/propidium iodide apoptosis assay. |
2016-03-17 |
2023-08-13 |
human |
| Wei Guo, Li Xie, Long Zhao, Yuehuan Zha. mRNA and microRNA expression profiles of radioresistant NCI-H520 non-small cell lung cancer cells. Molecular medicine reports. vol 12. issue 2. 2016-03-16. PMID:25873351. |
the radioresistant features were subsequently assessed using a clonogenic assay, analysis of apoptosis and an mtt assay, the gene expression levels were examined using an agilent whole human genome 4 x 44 k oligo microarray and agilent human mircury(™) lna array, and confirmed by reverse transcription-quantitative polymerase chain reaction. |
2016-03-16 |
2023-08-13 |
human |
| Chong-Zhi Bai, Ma-Li Feng, Xu-Liang Hao, Zhi-Juan Zhao, Yu-Ying Li, Zhuan-Hua Wan. Anti-tumoral effects of a trypsin inhibitor derived from buckwheat in vitro and in vivo. Molecular medicine reports. vol 12. issue 2. 2016-03-16. PMID:25901645. |
apoptosis in the h22 cell line induced by rbti was identified using mtt assays, dna electrophoresis, flow cytometry, morphological observation of the nuclei, measurement of cytochrome c and assessment of caspase activation. |
2016-03-16 |
2023-08-13 |
Not clear |
| Zhiyun Cao, Xuzheng Chen, Wei Lin, Jinyan Zhao, Liangpu Zheng, Hongzhi Ye, Lianming Liao, Jian D. Jiedu Xiaozheng Yin decoction inhibits hepatoma cell proliferation by inducing apoptosis via the mitochondrial-mediated pathway. Molecular medicine reports. vol 12. issue 2. 2016-03-16. PMID:25936398. |
following treatment of the hepg2 cells with ee-jxy for 24 h, cell viability, apoptosis, mitochondrial membrane potential, caspase enzyme activity and the expression levels of apoptotic-associated proteins (bcl-2 and bax) were detected by mtt, flow cytometry, elisa and western blotting respectively. |
2016-03-16 |
2023-08-13 |
mouse |
| Haibiao Guo, Haitao Wang, Canmao Wang, Yufang Cheng, Zhengqiang Zou, Yiwen Li, Jingang Wu, Jiangping X. C-Reactive Protein Induces Tau Hyperphosphorylation via GSK3β Signaling Pathway in SH-SY5Y Cells. Journal of molecular neuroscience : MN. vol 56. issue 2. 2016-03-14. PMID:25966642. |
treatment of cells with crp (5, 10, 20 μg/ml) resulted in neurotoxicity and apoptosis, as was observed by mtt assay and hoechst staining, respectively. |
2016-03-14 |
2023-08-13 |
Not clear |
| Jie Yang, Hai Jiang, Chunyu Wang, Bo Yang, Lijun Zhao, Dongling Hu, Guihua Qiu, Xiaolin Dong, Bin Xia. Oridonin triggers apoptosis in colorectal carcinoma cells and suppression of microRNA-32 expression augments oridonin-mediated apoptotic effects. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 72. 2016-03-14. PMID:26054686. |
in this work, to investigate its pharmacological effects on human colorectal carcinoma hct-116 and lovo cells, cell proliferation and apoptosis were respectively evaluated by 3-[4,5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide (mtt) assay, annexin v-fitc, and propidium iodide (pi) staining. |
2016-03-14 |
2023-08-13 |
mouse |
| Lu-Lu Wang, Zhong Xu, Yang Peng, Lu-Chun Li, Xiao-Ling W. Downregulation of inhibitor of apoptosis‑stimulating protein of p53 inhibits proliferation and promotes apoptosis of gastric cancer cells. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25846425. |
using mtt assays, colony-formation assays and flow cytometry, it was identified that the inhibition of iaspp was able to significantly inhibit the proliferation and colony forming ability and promote apoptosis in gc cells. |
2016-03-10 |
2023-08-13 |
mouse |
| Hongying Tian, Zhongcui Y. Resveratrol induces apoptosis of leukemia cell line K562 by modulation of sphingosine kinase-1 pathway. International journal of clinical and experimental pathology. vol 8. issue 3. 2016-03-10. PMID:26045781. |
the anti-proliferation effect of resveratrol-induced apoptosis on k562 cells were detected using mtt assay. |
2016-03-10 |
2023-08-13 |
human |
| Qing-Chun Li, Hong-Jun Li, Shi Liu, Yun Liang, Xue Wang, Lei Cu. Inhibition of γ-secretase by retinoic acid chalcone (RAC) induces G2/M arrest and triggers apoptosis in renal cell carcinoma. International journal of clinical and experimental pathology. vol 8. issue 3. 2016-03-08. PMID:26045747. |
mtt assay and flow cytometry analysis were used to determine cell proliferation and apoptosis along with cell cycle examination. |
2016-03-08 |
2023-08-13 |
Not clear |