| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianping Bi, Ai Huang, Tao Liu, Tao Zhang, Hong M. Expression of DNA damage checkpoint 53BP1 is correlated with prognosis, cell proliferation and apoptosis in colorectal cancer. International journal of clinical and experimental pathology. vol 8. issue 6. 2016-05-24. PMID:26261485. |
after establishment of shrna-mediated knockdown stable hct-116 cell lines, cell proliferation, apoptosis and cell cycle distribution were detected by mtt and flow cytometry, and expression of up-and down-steam related proteins as γ-h2ax, chk2 and p53 were tested by western blot. |
2016-05-24 |
2023-08-13 |
Not clear |
| Hai-ying Hui, Na Wu, Min Wu, Yang Liu, Sheng-xiang Xiao, Mei-fang Zhan. Dihydroartemisinin suppresses growth of squamous cell carcinoma A431 cells by targeting the Wnt/β-catenin pathway. Anti-cancer drugs. vol 27. issue 2. 2016-05-23. PMID:26457547. |
after stimulation of a431 cells and hacat cells (normal human keratinocyte cells, as control) with various doses of dha, the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) assay was used to assess the proliferation of both cell lines and cell apoptosis was analyzed by flow cytometric analysis. |
2016-05-23 |
2023-08-13 |
human |
| Dong Sun, Qingwei Yue, Weihua Guo, Tao Li, Jing Zhang, Guibao Li, Zengxun Liu, Jinhao Su. Neuroprotection of resveratrol against neurotoxicity induced by methamphetamine in mouse mesencephalic dopaminergic neurons. BioFactors (Oxford, England). vol 41. issue 4. 2016-05-20. PMID:26212417. |
cell viability was examined by mtt assay and the apoptosis was assessed using hoechst33342/pi double staining. |
2016-05-20 |
2023-08-13 |
mouse |
| Beibei Chu, Jiang Wang, Yueying Wang, Guoyu Yan. Knockdown of PKM2 induces apoptosis and autophagy in human A549 alveolar adenocarcinoma cells. Molecular medicine reports. vol 12. issue 3. 2016-05-18. PMID:26082202. |
an mtt assay was used to detect cell viability and flow cytometry was used to determine cell apoptosis. |
2016-05-18 |
2023-08-13 |
human |
| Araceli Gonzalez-Reyes, Ahmed Menaouar, Denis Yip, Bogdan Danalache, Eric Plante, Nicolas Noiseux, Jolanta Gutkowska, Marek Jankowsk. Molecular mechanisms underlying oxytocin-induced cardiomyocyte protection from simulated ischemia-reperfusion. Molecular and cellular endocrinology. vol 412. 2016-05-17. PMID:25963797. |
in comparison to normoxia, i-r resulted in decrease of formazan production by h9c2 cells to 63.5 ± 1.7% (mtt assay) and in enhanced apoptosis from 1.7 ± 0.3% to 2.8 ± 0.4% (tunel test). |
2016-05-17 |
2023-08-13 |
Not clear |
| Yang Xia, Zhicheng He, Bin Liu, Pengli Wang, Yijiang Che. Downregulation of Meg3 enhances cisplatin resistance of lung cancer cells through activation of the WNT/β-catenin signaling pathway. Molecular medicine reports. vol 12. issue 3. 2016-05-17. PMID:26059239. |
flow cytometric analysis and mtt assay were also used to investigate the cell cycle and apoptosis. |
2016-05-17 |
2023-08-13 |
human |
| Ju Yeon Kim, Jae-Jun Song, Byoung-Mog Kwon, Jong Dae Le. Tanshinone IIA exerts antitumor activity against vestibular schwannoma cells by inhibiting the expression of hypoxia-inducible factor-1α. Molecular medicine reports. vol 12. issue 3. 2016-05-17. PMID:26080622. |
cell viability was measured using an mtt assay and apoptosis was assessed by flow cytometry. |
2016-05-17 |
2023-08-13 |
Not clear |
| Xuexue Huang, Yuan Xu, Yanyi Liu, Hong Xie, Jiachun Wang, Zhigang W. Extracellular Ca(2+) Selectively Enhances Adriamycin-induced Cell Death in Human Hepatoma Cells. Current cancer drug targets. vol 15. issue 6. 2016-05-17. PMID:26282547. |
in the present study, the growth inhibition, apoptosis and necrosis rates of human normal embryo hepatic l02 and human hepatoma hepg2 cells exposed to additional calcium ([ca(2+)]a)and adriamycin (adm), a chemotherapeutic agent to treat hepatocellular carcinoma, were measured by mtt and annexin v/pi assays, respectively. |
2016-05-17 |
2023-08-13 |
human |
| Manman Huang, Defeng Pan, Yinping Du, Hong Zhu, Lin Zhang, Tongda Xu, Yuanyuan Luo, Dongye L. Na(+)/Ca(2+) exchanger 1 (NCX-1) mediates the anti-apoptotic effect of Akt1 in neonatal rat cardiomyocytes during ischemia/reperfusion. American journal of translational research. vol 8. issue 3. 2016-05-17. PMID:27186265. |
cardiomyocyte vitality was determined using mtt, and the apoptosis was determined by tunel to verify the anti-apoptotic role of akt1. |
2016-05-17 |
2023-08-13 |
rat |
| Fu-quan Zhang, Wen-tao Yang, Shan-zhou Duan, Ying-chen Xia, Rong-ying Zhu, Yong-bing Che. JAK2 inhibitor TG101348 overcomes erlotinib-resistance in non-small cell lung carcinoma cells with mutated EGF receptor. Oncotarget. vol 6. issue 16. 2016-05-12. PMID:25869210. |
cell proliferation, apoptosis, gene expression and tumor growth were evaluated by diphenyltetrazolium bromide (mtt) assay, flow cytometry, terminal deoxynucleotidyl transferase biotin-dutp nick end labeling (tunel) staining, western blot and a xenograft mouse model, respectively. |
2016-05-12 |
2023-08-13 |
mouse |
| Jia Wang, Jie Wu, Hong Wu, Xingzhen Liu, Yingjian Chen, Jianying Wu, Chengjin Hu, Dajin Zo. Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E-/- mice by activating autophagy. Molecular medicine reports. vol 12. issue 3. 2016-05-12. PMID:26080706. |
ins‑1 insulinoma pancreatic islet cell lines were treated with ffa and the levels of cell necrosis, apoptosis and autophagy were detected using an mtt assay, flow cytometry and electron microscopy (ecm). |
2016-05-12 |
2023-08-13 |
mouse |
| Tao Yin, Sisi He, Guobo Shen, Tinghong Ye, Fuchun Guo, Yongsheng Wan. Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model. Molecular medicine reports. vol 12. issue 3. 2016-05-12. PMID:26095429. |
cell apoptosis and proliferation were analyzed in vitro using flow cytometry (fcm) and the mtt assay, respectively. |
2016-05-12 |
2023-08-13 |
Not clear |
| Zhenran Wang, Bo Tang, Fang Tang, Yang Li, Guangyu Zhang, Li Zhong, Chencheng Dong, Songqing H. Protection of rat intestinal epithelial cells from ischemia/reperfusion injury by (D-Ala2, D-Leu5)-enkephalin through inhibition of the MKK7-JNK signaling pathway. Molecular medicine reports. vol 12. issue 3. 2016-05-12. PMID:26126577. |
to investigate the protective effect of dadle on hypoxia/reoxygenation injury in rat intestinal epithelial cells, rat intestinal epithelial cells were treated with different concentrations of dadle, following which the cell survival rate was determined using a tetrazolium (mtt) colorimetric assay, and apoptosis was determined using flow cytometry. |
2016-05-12 |
2023-08-13 |
rat |
| Zhi-qiang Yuan, Ji-zhao Li, Yang Liu, Wei-liang Chen, Shu-di Yang, Chun-ge Zhang, Wen-jing Zhu, Xiao-feng Zhou, Chun Liu, Xue-nong Zhan. Systemic delivery of micelles loading with paclitaxel using N-succinyl-palmitoyl-chitosan decorated with cRGDyK peptide to inhibit non-small-cell lung cancer. International journal of pharmaceutics. vol 492. issue 1-2. 2016-05-12. PMID:26188316. |
mtt assays and cell apoptosis studies revealed that cell viability was significantly inhibited by ptx/crgdyk-spcs micelles. |
2016-05-12 |
2023-08-13 |
Not clear |
| Jianqing Chen, Tejun Shu, Jian Chen, Man Ye, Zhengbing Lv, Zuoming Nie, Qijing Gai, Wei Yu, Yaozhou Zhan. Purification and Initial Functions of Sex-Specific Storage Protein 2 in Bombyx mori. The protein journal. vol 34. issue 4. 2016-05-11. PMID:26231571. |
in addition, using flow cytometry and the mtt assay, we found that ssp2 had anti-apoptotic effects on bmn cells, and that ssp2 could also inhibit cell apoptosis induced by chemical factors. |
2016-05-11 |
2023-08-13 |
Not clear |
| Jie Li, Feng-Quan Zhang, Zhen-Ning Du, Teng Cai, Peng-Shan Cai, Lei Fa. Protective effect of HO-1 transfection against ethanol-induced osteoblast damage. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 35. issue 3. 2016-05-10. PMID:26072076. |
after exposure to ethanol for 24 h, cytoactivity and apoptosis of osteoblasts were measured by mtt assay and flow cytometry, respectively. |
2016-05-10 |
2023-08-13 |
Not clear |
| Zohreh Aas, Esmaeil Babaei, Mohammad Ali Hosseinpour Feizi, Gholamreza Dehgha. Anti-proliferative and Apoptotic Effects of Dendrosomal Farnesiferol C on Gastric Cancer Cells. Asian Pacific journal of cancer prevention : APJCP. vol 16. issue 13. 2016-05-10. PMID:26225673. |
the 3-(4,5-dimethyl-thiazol-2yl)-2,5-diphenyl tetrazolium bromide (mtt) assay and reverse transcriptase-polymerase chain reaction (rt-pcr) were respectively used to detect the anti-proliferative properties of dfc and expression ratio of bax/bcl-2 as a hallmark of apoptosis. |
2016-05-10 |
2023-08-13 |
Not clear |
| Jing Jin, Zhongxin Li, Jianghui Liu, Yan Wu, Xing Gao, Yutong H. Knockdown of zinc transporter ZIP5 (SLC39A5) expression significantly inhibits human esophageal cancer progression. Oncology reports. vol 34. issue 3. 2016-05-09. PMID:26133979. |
we conducted mtt and cck-8 assays to determine the role of zip5 in cell proliferation, transwell assays to detect migration and invasion, and flow cytometry (fcm) to detect apoptosis and cell cycle percentage using kyse170k cells. |
2016-05-09 |
2023-08-13 |
human |
| Ge Xu, Ge Kuang, Wengao Jiang, Rong Jiang, Dianming Jian. Polydatin promotes apoptosis through upregulation the ratio of Bax/Bcl-2 and inhibits proliferation by attenuating the β-catenin signaling in human osteosarcoma cells. American journal of translational research. vol 8. issue 2. 2016-05-09. PMID:27158379. |
our results showed that pd dose-dependently inhibited proliferation and promoted apoptosis in 143b and mg63 osteosarcoma cells, examined by mtt assay and annexin v-fitc apoptosis detection. |
2016-05-09 |
2023-08-13 |
human |
| Ting Wang, Xia Gong, Rong Jiang, Hongzhong Li, Weimin Du, Ge Kuan. Ferulic acid inhibits proliferation and promotes apoptosis via blockage of PI3K/Akt pathway in osteosarcoma cell. American journal of translational research. vol 8. issue 2. 2016-05-09. PMID:27158383. |
in present study, ferulic acid inhibited proliferation and induced apoptosis in both 143b and mg63 osteosarcoma cells dose-dependently, indicated by mtt assay and annexin v-fitc apoptosis detection. |
2016-05-09 |
2023-08-13 |
Not clear |