Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Guijun Song, Yu Li, Lulu Lin, Yunpeng Ca. Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26459718. |
mtt assays demonstrated that memantine was able to upregulate neuronal cell survival, and acridine orange staining and flow cytometry demonstrated that memantine (5 µm) was able to inhibit neuronal autophagy and apoptosis. |
2016-08-15 |
2023-08-13 |
Not clear |
R Vahidi, S Safi, A Farsinejad, N Panah. Citrate and celecoxib induce apoptosis and decrease necrosis in synergistic manner in canine mammary tumor cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 61. issue 5. 2016-08-15. PMID:26475384. |
mtt assay was performed to determine cell viability, and annexin—pi test was performed to evaluate apoptosis induction. |
2016-08-15 |
2023-08-13 |
Not clear |
Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Pen. MicroRNA-92b promotes tumor growth and activation of NF-κB signaling via regulation of NLK in oral squamous cell carcinoma. Oncology reports. vol 34. issue 6. 2016-08-08. PMID:26503628. |
functionally, mir-92b was shown to not only promote the proliferation of oscc cells in mtt and colony formation and xenograft assays, but also to inhibit cell apoptosis in a flow cytometric assay. |
2016-08-08 |
2023-08-13 |
human |
Qiuzhen Zhu, Yuefan Zhang, Yulan Liu, Hao Cheng, Jing Wang, Yue Zhang, Yaocheng Rui, Tiejun L. MLIF Alleviates SH-SY5Y Neuroblastoma Injury Induced by Oxygen-Glucose Deprivation by Targeting Eukaryotic Translation Elongation Factor 1A2. PloS one. vol 11. issue 2. 2016-08-08. PMID:26918757. |
mtt assay was used to assess cell viability, and flow cytometry assay and hoechst staining were used to evaluate apoptosis. |
2016-08-08 |
2023-08-13 |
human |
Yingfeng Tu, Li Liu, Dongliang Zhao, Youbin Liu, Xiaowei Ma, Yuhua Fan, Lin Wan, Tao Huang, Zhen Cheng, Baozhong She. Overexpression of miRNA-497 inhibits tumor angiogenesis by targeting VEGFR2. Scientific reports. vol 5. 2016-08-03. PMID:26345385. |
in this work, cell proliferation and apoptosis analyses were conducted to explore the potential function of mir-497 in huvecs by using mtt and tunel assays. |
2016-08-03 |
2023-08-13 |
mouse |
Fei Han, Long Zhang, Yongxin Zhou, Xianghua Y. Caveolin-1 regulates cell apoptosis and invasion ability in paclitaxel-induced multidrug-resistant A549 lung cancer cells. International journal of clinical and experimental pathology. vol 8. issue 8. 2016-08-03. PMID:26464635. |
a mtt assay was used to determine cell proliferation, and flow cytometry was used to detect the cell cycle stage and apoptosis. |
2016-08-03 |
2023-08-13 |
human |
Xia Sheng, Wen-Bin Li, De-Lin Wang, Ke-Hong Chen, Jian-Jia Cao, Zhao Luo, Jiang He, Mei-Cai Li, Wu-Jiang Liu, Chao Y. YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells. Molecular medicine reports. vol 12. issue 4. 2016-08-02. PMID:26126522. |
mtt, flow cytometry, reverse transcription‑quantitative polymerase chain reaction and western blot assays were used to analyse the effects of yap inhibition on the proliferation and apoptosis of pc‑3 cells. |
2016-08-02 |
2023-08-13 |
human |
Jinquan Xu, Weiyun Xu, Jiaqun Zh. Propofol suppresses proliferation and invasion of glioma cells by upregulating microRNA-218 expression. Molecular medicine reports. vol 12. issue 4. 2016-08-02. PMID:26133092. |
the effects of propofol on u373 glioblastoma cell proliferation, apoptosis and invasion were detected by an mtt assay, caspase‑3 activity measurement and a matrigel™ invasion assay, respectively. |
2016-08-02 |
2023-08-13 |
human |
Zohreh Safari, Reza Safaralizadeh, Mir Hadi Seyedzadeh, Ayla Valinezad Orang, Ahad Zare, Mohammad Ali Hosseinpour Feizi, Gholam Ali Karda. The Induction of Metformin Inhibitory Effects on Tumor Cell Growth in Hypoxic Condition. Iranian journal of allergy, asthma, and immunology. vol 14. issue 6. 2016-08-02. PMID:26725558. |
the proliferation, apoptosis, and necrosis rate were assessed using mtt test and annexin v assay. |
2016-08-02 |
2023-08-13 |
Not clear |
G Prem Kumar, Jagadeesh S Sanganal, A R Phani, C Manohara, Syamantak M Tripathi, H L Raghavendra, P B Janardhana, S Amaresha, K B Swamy, R G S V Prasa. Anti-cancerous efficacy and pharmacokinetics of 6-mercaptopurine loaded chitosan nanoparticles. Pharmacological research. vol 100. 2016-08-01. PMID:26232590. |
the nanoformulations showed enhanced in vitro anti-cancer activities (mtt assay, apoptosis assay, cell cycle arrest and ros indices) on ht-1080 and mcf-7 cells. |
2016-08-01 |
2023-08-13 |
Not clear |
Ebrahim Eftekhar, Hajar Jaberie, Fakhraddin Naghibalhossain. Carcinoembryonic Antigen Expression and Resistance to Radiation and 5-Fluorouracil-Induced Apoptosis and Autophagy. International journal of molecular and cellular medicine. vol 5. issue 2. 2016-08-01. PMID:27478804. |
mtt assay was used to measure ic50 value of the cells exposed to graded concentrations of 5- fu with either 0.1 mm nab or 1 μm 5-aza for 72 h . using cho- and sw742-cea transfectants, we also investigated the effect of cea expression on uv- and 5-fu-induced apoptosis and autophagy. |
2016-08-01 |
2023-08-13 |
Not clear |
Lichun Sun, Mingqiu Liu, Guang-Chun Sun, Xu Yang, Qingqing Qian, Shuyu Feng, L Vienna Mackey, David H Co. Notch Signaling Activation in Cervical Cancer Cells Induces Cell Growth Arrest with the Involvement of the Nuclear Receptor NR4A2. Journal of Cancer. vol 7. issue 11. 2016-07-29. PMID:27471554. |
particularly, the nuclear receptor nr4a2 was observed to induce cell proliferation via mtt assay and reduce cell apoptosis via facs assay. |
2016-07-29 |
2023-08-13 |
Not clear |
Yingying Sun, Yuanhai Li, Lei Liu, Yiqiao Wang, Yingjing Xia, Lingli Zhang, Xuewu J. Identification of miRNAs Involved in the Protective Effect of Sevoflurane Preconditioning Against Hypoxic Injury in PC12 Cells. Cellular and molecular neurobiology. vol 35. issue 8. 2016-07-28. PMID:25982511. |
finally, after transfection of mirna (mir-101a or mir-34b) mimics or inhibitor, mtt and flow cytometry assays were used to evaluate cell survival and apoptosis in sevoflurane preconditioning. |
2016-07-28 |
2023-08-13 |
Not clear |
Yazhuo Jiang, Yili Wang, Liang Liang, Yang Gao, Juan Chen, Yi Sun, Yongyi Cheng, Yonggang X. IL-37 mediates the antitumor activity in renal cell carcinoma. Medical oncology (Northwood, London, England). vol 32. issue 11. 2016-07-28. PMID:26464282. |
cell migration, proliferation, and apoptosis were tested by wound-healing assay, mtt, and flow cytometry, respectively. |
2016-07-28 |
2023-08-13 |
mouse |
Hui Liu, Hui-qin Cao, Jin-bao Ta, Wen Zhang, Yu-hong Li. Knockdown of Peripheral Myelin Protein 22 Inhibits the Progression of Chronic Myeloid Leukemia. Oncology research. vol 22. issue 5-6. 2016-07-28. PMID:26629937. |
cell viability and apoptosis were, respectively, determined by mtt assay and flow cytometry. |
2016-07-28 |
2023-08-13 |
human |
Li-Cheng Jiang, Zhi-Yuan Xin, Baremberg Deborah, Jun-Sheng Zhang, Dao-Ying Yuan, Kai Xu, Xian-Bin Liu, Hu-Quan Jiang, Qing-Chun Fan, Bin Zhang, Ke-Yi L. Inhibition of autophagy augments apoptosis in human oral squamous cell carcinoma under nutrient depletion. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 44. issue 5. 2016-07-27. PMID:25212667. |
cell death and apoptosis induced by nutrient depletion was measured using both mtt assay and flow cytometry (fcm). |
2016-07-27 |
2023-08-13 |
human |
T Liu, Y-F Peng, C Jia, B-H Yang, X Tao, X Fang, W Zhon. Effect of HGF on the apoptosis of rat corpus cavernosum smooth muscle cells induced by TGFβ1. Andrologia. vol 47. issue 9. 2016-07-19. PMID:25385280. |
differences in cell viability and apoptosis among groups were observed by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (mtt) assay and flow cytometry. |
2016-07-19 |
2023-08-13 |
rat |
Jie Zhang, Wenjing Wang, Lin Qian, Qiuwan Zhang, Dongmei Lai, Cong Q. Ursolic acid inhibits the proliferation of human ovarian cancer stem-like cells through epithelial-mesenchymal transition. Oncology reports. vol 34. issue 5. 2016-07-18. PMID:26323892. |
mtt assay and flow cytometry were used for cell viability and apoptosis analysis, and qrt-pcr for stem cell markers and epithelial-mesenchymal transition (emt) markers for mrna expression. |
2016-07-18 |
2023-08-13 |
mouse |
Baiyan Wang, Qianqian Han, Yanqin Zh. Oxymatrine inhibited cell proliferation by inducing apoptosis in human lung cancer A549 cells. Bio-medical materials and engineering. vol 26 Suppl 1. 2016-07-14. PMID:26405930. |
the a549 cells inhibition rate, apoptosis, and the expression of bcl-2 and bax were examined by mtt method, annexin v/pi double staining method, real-time quantitative pcr and western blot, respectively. |
2016-07-14 |
2023-08-13 |
human |
J Qin, J-A Teng, Z Zhu, J-X Chen, Y-Y W. Glargine Promotes Human Colorectal Cancer Cell Proliferation via Upregulation of miR-95. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 47. issue 11. 2016-07-09. PMID:25671802. |
effect of glargine on the cell proliferation was tested in hct-116 and sw480 cells by mtt assay, and apoptosis was measured by flow cytometry. |
2016-07-09 |
2023-08-13 |
human |