| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping-Chun Li, Yun-Chen Tien, Cecilia Hsuan Day, Peiying Pai, Wei-Wen Kuo, Tung-Sheng Chen, Chia-Hua Kuo, Chang-Hai Tsai, Da-Tong Ju, Chih-Yang Huan. Impact of LPS-induced cardiomyoblast cell apoptosis inhibited by earthworm extracts. Cardiovascular toxicology. vol 15. issue 2. 2016-01-15. PMID:25249212. |
cell apoptosis was detected using mtt, ldh, tunel assay and jc-1 staining. |
2016-01-15 |
2023-08-13 |
Not clear |
| Jie Wang, Chao Chen, Shiying Wang, Yong Zhang, Peihao Yin, Zhongxiang Gao, Jie Xu, Dianxu Feng, Qinsong Zuo, Ronghua Zhao, Teng Che. Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways. Gastroenterology research and practice. vol 2015. 2016-01-15. PMID:26770191. |
cell proliferation, apoptosis, and cycling were determined by mtt, annexin v/pi staining, and flow cytometry, respectively. |
2016-01-15 |
2023-08-13 |
mouse |
| Yu-Lin Liu, Ya-Nan Su. Down-regulation of testes-specific protease 50 induces apoptosis in human laryngocarcinoma HEp2 cells in a NF-κB-mediated pathway. Molecular biology reports. vol 41. issue 12. 2016-01-13. PMID:25399078. |
by using mtt, wound healing, flow cytometric and tumorigenesis assays, the study tested the tsp50 role in human laryngocarcinoma cell growth and apoptosis. |
2016-01-13 |
2023-08-13 |
mouse |
| Jin Hou, Man Mi, Ming Wei, Wen-hui Y. [Photothermal effects of metallic carbon nanotubes on human breast cancer cells]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 50. issue 8. 2016-01-12. PMID:26668997. |
the effects of m-swnts on mcf-7 cell proliferation and apoptosis were evaluated with mtt assay and flow cytometry, respectively. |
2016-01-12 |
2023-08-13 |
human |
| b' Tatjana Kastratovi\\xc4\\x87, Slobodan Arsenijevi\\xc4\\x87, Zoran Matovi\\xc4\\x87, Marina Mitrovi\\xc4\\x87, Ivana Nikoli\\xc4\\x87, Zoran Milosavljevi\\xc4\\x87, Zoran Protrka, Marija \\xc5\\xa0orak, Janko \\xc4\\x90uri\\xc4\\x8. METHOTREXATE AND MYOTREXATE INDUCE APOPTOSIS IN HUMAN MYOMA FIBROBLASTS (T hES CELL LINE) VIA MITOCHONDRIAL PATHWAY. Acta poloniae pharmaceutica. vol 72. issue 3. 2016-01-11. PMID:26642654.' |
cells were treated with a graded concentrations of both mtx and myothrexate (0.1-16 µm) for 24 h. the cytotoxicity was assayed by mtt test, apoptosis was evaluated by annexin v-fitc assay and their possible role in apoptosis was determined by immnu- flourescence. |
2016-01-11 |
2023-08-13 |
human |
| Ya-Ping Zhang, Qing-Hong Kong, Ying Huang, Guan-Lin Wang, Kwen-Jen Chan. Inhibition of c-FLIP by RNAi enhances sensitivity of the human osteogenic sarcoma cell line U2OS to TRAIL-induced apoptosis. Asian Pacific journal of cancer prevention : APJCP. vol 16. issue 6. 2016-01-08. PMID:25824746. |
cell death effects and apoptosis were measured by the methods of mtt assay with 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide and flow cytometry, respectively. |
2016-01-08 |
2023-08-13 |
human |
| Tao Hu, Ya-Shan Li, Bo Chen, Ye-Fei Chang, Guang-Cai Liu, Ying Hong, Hong-Lan Chen, Yan-Bin Xiyan. Elevated glucose-6-phosphate dehydrogenase expression in the cervical cancer cases is associated with the cancerigenic event of high-risk human papillomaviruses. Experimental biology and medicine (Maywood, N.J.). vol 240. issue 10. 2016-01-04. PMID:25616277. |
mtt and flow cytometry were also employed to determine the survival and apoptosis of cc cells after g6pd expressional inhibition. |
2016-01-04 |
2023-08-13 |
human |
| Wei Ma, Meng Na, Chongyang Tang, Haiyang Wang, Zhiguo Li. Overexpression of N-myc downstream-regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3-kinase/AKT pathways. Molecular medicine reports. vol 12. issue 1. 2016-01-04. PMID:25777142. |
cell proliferation, invasion, apoptosis and cell cycle arrest were subsequently examined by mtt assay, transwell chamber assay, flow cytometry and western blot analysis, respectively. |
2016-01-04 |
2023-08-13 |
mouse |
| Yong Zhang, Wei Qin, Longyin Zhang, Xianxian Wu, Ning Du, Yingying Hu, Xiaoguang Li, Nannan Shen, Dan Xiao, Haiying Zhang, Zhange Li, Yue Zhang, Huan Yang, Feng Gao, Zhimin Du, Chaoqian Xu, Baofeng Yan. MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis. Scientific reports. vol 5. 2016-01-04. PMID:25801675. |
forced expression of mir-26a inhibited endothelial apoptosis as evidenced by mtt assay and tunel staining results. |
2016-01-04 |
2023-08-13 |
mouse |
| Jiaming Mei, Chaoshi Ni. Protective and reversal effects of conserved dopamine neurotrophic factor on PC12 cells following 6-hydroxydopamine administration. Molecular medicine reports. vol 12. issue 1. 2015-12-31. PMID:25738732. |
cell growth was assessed using an mtt assay, the rate of cell apoptosis was detected using flow cytometry and the apoptotic morphology of cells was observed using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (tunel) staining. |
2015-12-31 |
2023-08-13 |
Not clear |
| Binhui Xie, Qinshan Zen, Xiaonong Wang, Xiao He, Yuankang Xie, Zixiang Zhang, Heping L. ACK1 promotes hepatocellular carcinoma progression via downregulating WWOX and activating AKT signaling. International journal of oncology. vol 46. issue 5. 2015-12-29. PMID:25738261. |
flow cytometry, caspase 3/7 activity assay, brdu cell proliferation assay, mtt assay and transwell assay were used to detect apoptosis, proliferation, invasion and migration of hcc cells. |
2015-12-29 |
2023-08-13 |
Not clear |
| Kehan Li, Xuechang Ha. Endoplasmic reticulum stress is involved in the lidocaine-induced apoptosis in SH-SY5Y neuroblastoma cells. Journal of molecular neuroscience : MN. vol 56. issue 1. 2015-12-24. PMID:25522790. |
firstly, we confirmed that lidocaine treatment induced apoptosis in sh-sy5y cells, time-dependently and dose-dependently, via mtt cell viability assay and annexin v/fitc apoptosis detection with a facscan flow cytometer. |
2015-12-24 |
2023-08-13 |
human |
| Luana Dalbem Murad, Nathalia da Costa Pereira Soares, Camila Brand, Mariana Costa Monteiro, Anderson Junger Teodor. Effects of caffeic and 5-caffeoylquinic acids on cell viability and cellular uptake in human colon adenocarcinoma cells. Nutrition and cancer. vol 67. issue 3. 2015-12-24. PMID:25803129. |
cell viability, cell cycle, and apoptosis was measured, respectively, using mtt method and flow cytometry. |
2015-12-24 |
2023-08-13 |
human |
| Wenqing Yan, Rong Li, Jie He, Juan Du, Jian Ho. Importin β1 mediates nuclear factor-κB signal transduction into the nuclei of myeloma cells and affects their proliferation and apoptosis. Cellular signalling. vol 27. issue 4. 2015-12-22. PMID:25643631. |
furthermore, the proliferation of mm cells was inhibited, as demonstrated by mtt assay results, and the mm cell apoptosis rate was higher, as demonstrated by the annexin v/propidium iodide (pi) double-staining assay results. |
2015-12-22 |
2023-08-13 |
Not clear |
| Liyuan Wu, Si Li, Rui Peng, Shu Gong, Liu Xu, Fangdong Zo. [Drug resistance of colon cancer cells to 5-fluorouracil mediated by microRNA-21]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 32. issue 5. 2015-12-22. PMID:26418978. |
results mtt assay reveals that the ic50 of 5-fu in rko-wt cells (52.82 ± 0.06 umol/l) was about 67% higher than in mir-21 knockout cells (32.23 ± 0.05 umol/l) (p < 0.05), and the apoptosis ratio elevated after knockout of mir-21. |
2015-12-22 |
2023-08-13 |
Not clear |
| Wenlei Zhuo, Liang Zhang, Yi Zhu, Bo Zhu, Zhengtang Che. Fisetin, a dietary bioflavonoid, reverses acquired Cisplatin-resistance of lung adenocarcinoma cells through MAPK/Survivin/Caspase pathway. American journal of translational research. vol 7. issue 10. 2015-12-22. PMID:26692948. |
proliferation ability was assessed by mtt analysis and apoptosis was detected by flow cytometry. |
2015-12-22 |
2023-08-13 |
Not clear |
| Ferhat Hanikoglu, Aysegul Cort, Hakan Ozben, Aysegul Hanikoglu, Tomris Ozbe. Epoxomicin Sensitizes Resistant Osteosarcoma Cells to TRAIL Induced Apoptosis. Anti-cancer agents in medicinal chemistry. vol 15. issue 4. 2015-12-21. PMID:25666501. |
we determined the cytotoxic effects of epoxomicin and/or trail on these two types of os cells using dimethylthiazolyl 2,5 diphenyltetrazolium bromide (mtt) test and measured apoptosis markers such as pro-apoptotic bax levels and caspase-3, -8, -9 activities. |
2015-12-21 |
2023-08-13 |
Not clear |
| Bhavna Kumar, Arti Yadav, Kalman Hideg, Periannan Kuppusamy, Theodoros N Teknos, Pawan Kuma. A novel curcumin analog (H-4073) enhances the therapeutic efficacy of cisplatin treatment in head and neck cancer. PloS one. vol 9. issue 3. 2015-12-17. PMID:24675768. |
in addition, pretreatment of cisplatin-resistant hnscc cell lines with h-4073 significantly reversed the chemo-resistance as observed by cell viability assay (mtt), apoptosis assay (annexin v binding) and cleaved caspase-3 (western blot). |
2015-12-17 |
2023-08-12 |
mouse |
| Raktim Biswas, Phil-Sang Chung, Jeong Hwan Moon, Seung-Ha Lee, Jin-Chul Ah. Carboplatin synergistically triggers the efficacy of photodynamic therapy via caspase 3-, 8-, and 12-dependent pathways in human anaplastic thyroid cancer cells. Lasers in medical science. vol 29. issue 3. 2015-12-15. PMID:24114422. |
several parameters like cytotoxicity assay by mtt, apoptosis study by annexin v and propidium iodide, cell cycle analysis by flow cytometry, confocal microscopic study, and western blot analysis for different apoptosis-related proteins like bax, cytochrome c, caspases 3, 9, 8, and 12, etc. |
2015-12-15 |
2023-08-12 |
human |
| Alireza Abdanipour, Mohsen Sagha, Ali Noori-Zadeh, Iraj Pakzad, Taki Tiraih. In vitro study of the long-term cortisol treatment effects on the growth rate and proliferation of the neural stem/precursor cells. Neurological research. vol 37. issue 2. 2015-12-15. PMID:25082549. |
using mtt assay, acridine orange, and tunel assay, we have demonstrated that cortisol at high and excessive (more than 5 μm) levels had anti-proliferative effects on the nspcs derived from subventricular and subgranular zones in a dose- and time-dependent manner through apoptosis as well as necrosis. |
2015-12-15 |
2023-08-13 |
Not clear |