| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tianjun Chen, Fei Gao, Sifang Feng, Tian Yang, Mingwei Che. MicroRNA-134 regulates lung cancer cell H69 growth and apoptosis by targeting WWOX gene and suppressing the ERK1/2 signaling pathway. Biochemical and biophysical research communications. vol 464. issue 3. 2015-11-09. PMID:26166818. |
lactate dehydrogenase (ldh) assay, mtt assays and flow cytometry were performed in order to clarify the growth and apoptosis of sclc cells which had been transfected with mir-134 mimics or anti-mir-134. |
2015-11-09 |
2023-08-13 |
Not clear |
| Tiziano Baroni, Cinzia Lilli, Catia Bellucci, Giovanni Luca, Francesca Mancuso, Francesca Fallarino, Giulia Falabella, Iva Arato, Mario Calvitti, Lorella Marinucci, Giacomo Muzi, Marco Dell'Omo, Angela Gambelunghe, Maria Bod. In vitro cadmium effects on ECM gene expression in human bronchial epithelial cells. Cytokine. vol 72. issue 1. 2015-11-04. PMID:25541143. |
to study apoptosis cascade, annexin assay and cellular cytotoxicity by mtt assay were performed. |
2015-11-04 |
2023-08-13 |
human |
| Cheng-Lin Zhang, Ce Wang, Wang-Jun Yan, Rui Gao, Yong-Hua Li, Xu-Hui Zho. Knockdown of TNFAIP1 inhibits growth and induces apoptosis in osteosarcoma cells through inhibition of the nuclear factor-κB pathway. Oncology reports. vol 32. issue 3. 2015-11-03. PMID:24969828. |
a loss-of-function experiment was performed to explore the effects of lentiviral-mediated tnfaip1 sirna (sitnfaip1) on cell proliferation, invasive potential and apoptosis by mtt and transwell assays and flow cytometric analysis in os (mg-63 and u-2 os) cells. |
2015-11-03 |
2023-08-13 |
human |
| Yanpei Sun, Yan Zhao, Liying Hou, Xuguang Zhang, Zhihong Zhang, Kun W. RRR-α-tocopheryl succinate induces apoptosis in human gastric cancer cells via the NF-κB signaling pathway. Oncology reports. vol 32. issue 3. 2015-11-03. PMID:24970592. |
cell viability and apoptosis were respectively estimated by methylthiazol tetrazolium (mtt) assay and the annexin v‑fitc method. |
2015-11-03 |
2023-08-13 |
human |
| Kunshou Zhu, Weimin Fang, Yuanmei Chen, Shaofeng Lin, Xiaohui Che. TNF-related apoptosis-inducing ligand enhances vinorelbine-induced apoptosis and antitumor activity in a preclinical model of non-small cell lung cancer. Oncology reports. vol 32. issue 3. 2015-11-03. PMID:25017445. |
using the human nsclc cell line (a549) and a balb/c nude mice model, we observed the cell viability (mtt assay), cell apoptosis [hoechst staining, annexin v/propidium iodide (pi) staining assay, immunohistochemical staining, rt-pcr and western blotting] and cell proliferation (soft agar colony formation and cell cycle assay). |
2015-11-03 |
2023-08-13 |
mouse |
| Henry Aceros, Georges Farah, Nicolas Noiseux, Suhayla Mukaddam-Dahe. Moxonidine modulates cytokine signalling and effects on cardiac cell viability. European journal of pharmacology. vol 740. 2015-11-03. PMID:25036265. |
studies were performed on neonatal rat cardiomyocytes and fibroblasts incubated with interleukin (il)-1β (5 ng/ml), tumor necrosis factor (tnf)-α (10 ng/ml), and moxonidine (10(-7) and 10(-5) m), separately and in combination, for 15 min, and 24 and 48 h for the measurement of mapks (erk1/2, jnk, and p38) and akt activation and inducible nos (inos) expression, by western blotting, and cardiac cell viability/proliferation and apoptosis by flow cytometry, mtt assay, and live/dead assay. |
2015-11-03 |
2023-08-13 |
rat |
| Xian-Zhe Dong, Ting-Ting Xie, Xiao-Jiang Zhou, Li-Hua Mu, Xiao-Li Zheng, Dai-Hong Guo, Ping Liu, Xiao-Yue G. AG4, a compound isolated from Radix Ardisiae Gigantifoliae, induces apoptosis in human nasopharyngeal cancer CNE cells through intrinsic and extrinsic apoptosis pathways. Anti-cancer drugs. vol 26. issue 3. 2015-11-03. PMID:25521557. |
cell viability was assessed using the mtt reduction assay, and the effects of ag4 on apoptosis, reactive oxygen species (ros) content, mitochondrial membrane potential (mmp), and cell cycle were detected using a flow cytometer; the glutathione, superoxide dismutase and malondialdehyde activities were measured using colorimetric methods. |
2015-11-03 |
2023-08-13 |
human |
| Hong Zhang, Zhihong Li, Kaizhong Wang, Ping Re. Combined treatment of XIAP-targeting shRNA and celecoxib synergistically inhibits the tumor growth of non‑small cell lung cancer cells in vitro and in vivo. Oncology reports. vol 33. issue 3. 2015-11-03. PMID:25524805. |
the cells were then treated with cxb and xiap-shrna alone or in combination for indicated time periods, and the treatments were assessed for their effects on cell proliferation, apoptosis, migration, invasion and receptor signaling using the mtt, tunel, wound healing and matrigel invasion assays and western blotting, respectively. |
2015-11-03 |
2023-08-13 |
Not clear |
| Jiake Feng, Tieliang Ma, Zhijun Ge, Jie Lin, Weiliang Ding, Hong Chen, Wenjiao Zhu, Sujun Zhou, Yongfei Ta. PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways. Molecular medicine reports. vol 11. issue 3. 2015-10-30. PMID:25411978. |
cell proliferation was measured via an mtt assay, cell migration and invasion was measured via transwell® chambers, and the effect of pkm2 on apoptosis was detected from b‑cell lymphoma 2 (bcl‑2) and bcl‑2‑associated x protein expression levels. |
2015-10-30 |
2023-08-13 |
human |
| Jianping Chen, Lin Li, Jianyu Su, Bing Li, Tianfeng Chen, Yum-Shing Won. Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin. PloS one. vol 9. issue 6. 2015-10-28. PMID:24971451. |
this study was to investigate the synergistic effect of nb/cur on growth and apoptosis in a375 human melanoma cell line by mtt assay, flow cytometry and western blotting. |
2015-10-28 |
2023-08-13 |
human |
| Shayan Sarkar, Sumeet Jain, Vineeta Rai, Dipak K Sahoo, Sumita Raha, Sujit Suklabaidya, Shantibhusan Senapati, Vivek M Rangnekar, Indu B Maiti, Nrisingha De. Plant-derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) exhibits growth inhibitory effects in prostate cancer cells. Frontiers in plant science. vol 6. 2015-10-27. PMID:26500666. |
furthermore, various in vitro studies like mammalian cells proliferation assay (mtt), apoptosis induction assays, and nf-κb suppression suggested the cytotoxic and apoptotic properties of plant-derived sac-par-4-gfp against multiple prostate cancer cell lines. |
2015-10-27 |
2023-08-13 |
rat |
| Jue Xu, Gang Ren, De-An Zhao, Bo-An Li, Cheng-Fu Cai, Yi Zhou, Xian-Yang Lu. Downregulated Chibby in laryngeal squamous cell carcinoma with increased expression in laryngeal carcinoma Hep-2 cells. Oncology reports. vol 32. issue 5. 2015-10-26. PMID:25175341. |
proliferation, clone forming ability, cell cycle distribution and cell apoptosis of hep-2 cells were detected by mtt assay, plate colony forming assay, flow cytometry and tunel assay, respectively. |
2015-10-26 |
2023-08-13 |
human |
| Chao Shang, Yan Guo, Yang Hong, Yun-hui Liu, Yi-xue Xu. MiR-21 up-regulation mediates glioblastoma cancer stem cells apoptosis and proliferation by targeting FASLG. Molecular biology reports. vol 42. issue 3. 2015-10-26. PMID:25394756. |
the apoptosis and proliferation ability of mir-21 in gscs were analyzed by mtt and flow cytometry assay after anti-mir-21 transfection. |
2015-10-26 |
2023-08-13 |
Not clear |
| Yanmei Zou, Xiaomin Qin, Hua Xiong, Feng Zhu, Tao Chen, Hongge W. Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 7. 2015-10-26. PMID:25652471. |
3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and annexin v/propidium iodide (pi) staining assays demonstrated that evodiamine or mtdh short hairpin rna (shrna) significantly inhibited proliferation of a549 cells via induction of apoptosis. |
2015-10-26 |
2023-08-13 |
human |
| Xiaohua Zhang, Xianjin Wang, Tianyuan Xu, Shan Zhong, Zhoujun She. Targeting of mTORC2 may have advantages over selective targeting of mTORC1 in the treatment of malignant pheochromocytoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 7. 2015-10-26. PMID:25666752. |
mtt assay, apoptosis analysis, wound healing, and transwell approach were performed. |
2015-10-26 |
2023-08-13 |
mouse |
| Zhongchan Sun, Xinxing Song, Xiujuan Li, Tao Su, Shun Qi, Ruirui Qiao, Fu Wang, Yi Huan, Weidong Yang, Jing Wang, Yongzhan Nie, Kaichun Wu, Mingyuan Gao, Feng Ca. In vivo multimodality imaging of miRNA-16 iron nanoparticle reversing drug resistance to chemotherapy in a mouse gastric cancer model. Nanoscale. vol 6. issue 23. 2015-10-23. PMID:25327162. |
after co-culture with mir16/mnps, adr-induced apoptosis of sgc7901/adr was examined by mtt and tunel. |
2015-10-23 |
2023-08-13 |
mouse |
| Fen Chen, Shuangshuang Song, Hongwei Wang, Wenji Zhang, Congcong Lin, Shilin Ma, Tiantian Ye, Ling Zhang, Xinggang Yang, Xingjun Qin, Weisan Pa. Injectable chitosan thermogels for sustained and localized delivery of pingyangmycin in vascular malformations. International journal of pharmaceutics. vol 476. issue 1-2. 2015-10-20. PMID:25283699. |
the results measured by mtt assay showed that pym thermogels could inhibit proliferation and induce apoptosis of ea.hy926 cells in a concentration and time dependent manner. |
2015-10-20 |
2023-08-13 |
rabbit |
| Kuiqing Li, Cheng Liu, Bangfen Zhou, Liangkuan Bi, Hai Huang, Tianxin Lin, Kewei X. Role of EZH2 in the growth of prostate cancer stem cells isolated from LNCaP cells. International journal of molecular sciences. vol 14. issue 6. 2015-10-19. PMID:23739676. |
cell growth was investigated by mtt, cell cycle and apoptosis of pcscs were explored by flow cytometric analysis. |
2015-10-19 |
2023-08-12 |
human |
| Pegah Mirzapur, Zahra Rashidi, Leila Rezakhani, Mozafar Khazae. In vitro inhibitory effect of crab shell extract on human umbilical vein endothelial cell. In vitro cellular & developmental biology. Animal. vol 51. issue 1. 2015-10-19. PMID:25159724. |
crab sell extract was prepared and the effect of its various concentrations (0, 100, 200, 400, 800, 1000 μg/ml) on huvecs were surveyed in three periods of 24, 48 and 72 h. huvec viability, nitric oxide (no) secretion and apoptosis were assessed by mtt, griess and tunnel methods, respectively. |
2015-10-19 |
2023-08-13 |
human |
| Hui Gao, Qixiao Jiang, Yantao Han, Jianjun Peng, Chunbo Wan. Hispidulin potentiates the antitumor effect of sunitinib against human renal cell carcinoma in laboratory models. Cell biochemistry and biophysics. vol 71. issue 2. 2015-10-16. PMID:25260394. |
after treatment with hispidulin or sunitinib, either alone or in combination, mtt assay was used to examine cell viability and flow cytometry analysis was employed to examine cell cycle distribution and apoptosis of the rcc cell lines 786-0 and caki-1. |
2015-10-16 |
2023-08-13 |
mouse |