| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xu Yan, Jinrong Xue, Hongjin Wu, Shengqi Wang, Yuna Liu, Sidao Zheng, Chengying Zhang, Cui Yan. Ginsenoside-Rb1 Protects Hypoxic- and Ischemic-Damaged Cardiomyocytes by Regulating Expression of miRNAs. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-06-15. PMID:26074986. |
cell growth, proliferation, and apoptosis were detected by mtt and flow cytometry. |
2015-06-15 |
2023-08-13 |
rat |
| Tereza Cristina da Silva, Bruno Cogliati, Andréia Oliveira Latorre, Gokithi Akisue, Márcia Kazumi Nagamine, Mitsue Haraguchi, Daiane Hansen, Daniel Soares Sanches, Maria Lúcia Zaidan Dagl. Pfaffosidic Fraction from Hebanthe paniculata Induces Cell Cycle Arrest and Caspase-3-Induced Apoptosis in HepG2 Cells. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-06-15. PMID:26075002. |
cellular viability, proliferation, and apoptosis were evaluated, respectively, by mtt assay, brdu incorporation, activated caspase-3 immunocytochemistry, and dna fragmentation assay. |
2015-06-15 |
2023-08-13 |
human |
| Banashree Bondhopadhyay, Anuradha Moirangthem, Anupam Bas. Innate adjuvant receptor Toll-like receptor 3 can promote breast cancer through cell surface. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 2. 2015-06-12. PMID:25348355. |
tlr-3 was stimulated by poly (i:c) on the surface of human breast cancer cells mcf-7 and mda-mb-231 for up to 72 h. to check the cell survival and growth, thiazol blue tetrazolium bromide (mtt) assay, apoptosis assay, and cell cycle analysis were carried out. |
2015-06-12 |
2023-08-13 |
human |
| Qingjuan Liu, Ruiying Wang, Hong Zhou, Lihui Zhang, Yanping Cao, Xianjuan Wang, Yongmei Ha. SHIP2 on pI3K/Akt pathway in palmitic acid stimulated islet β cell. International journal of clinical and experimental medicine. vol 8. issue 3. 2015-06-11. PMID:26064210. |
cell proliferation and apoptosis were measured by mtt and flow cytometry. |
2015-06-11 |
2023-08-13 |
Not clear |
| Jinjun Ye, Li Yin, Peng Xie, Jianfeng Wu, Jian Huang, Guoren Zhou, Hanzi Xu, Emei Lu, Xia H. Antiproliferative effects and molecular mechanisms of troglitazone in human cervical cancer in vitro. OncoTargets and therapy. vol 8. 2015-06-10. PMID:26060406. |
cell viability was measured by 3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide (mtt) assay; cell cycle and apoptosis were detected by flow cytometry; and morphology of siha cells was observed under an inverted microscope. |
2015-06-10 |
2023-08-13 |
human |
| Taofeng Zhu, Ruhua Chen, Hao Yu, Yan Feng, Jianqiang Chen, Qin Lu, Jing Xie, Weiliang Ding, Tieliang M. Antitumor effect of a copper (II) complex of a coumarin derivative and phenanthroline on lung adenocarcinoma cells and the mechanism of action. Molecular medicine reports. vol 10. issue 5. 2015-06-09. PMID:25176185. |
an mtt assay was performed to determine the cell proliferation ratio, cell apoptosis was detected by annexin v/propidium iodide staining with flow cytometric analysis and western blot analysis was employed to evaluate the expression levels of apoptosis-associated proteins. |
2015-06-09 |
2023-08-13 |
mouse |
| Linbo Wang, Yang Zeng, Ye Liu, Xuansheng Hu, Shuhong Li, Yuepeng Wang, Ling Li, Zhongfang Lei, Zhenya Zhan. Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin. Acta biochimica et biophysica Sinica. vol 46. issue 10. 2015-06-09. PMID:25187415. |
mtt analysis results showed that 5 and 10 μm fucoxanthin inhibited the proliferation of t24 cells in a dose- and time-dependent manner accompanied by the growth arrest at g0/g1 phase of cell cycle, which is mediated by the up-regulation of p21, a cyclin-dependent kinase (cdk)-inhibitory protein and the down-regulation of cdk-2, cdk-4, cyclin d1, and cyclin e. in addition, 20 and 40 μm fucoxanthin induced apoptosis of t24 cells by the abrogation of mortalin-p53 complex and the reactivation of nuclear mutant-type p53, which also had tumor suppressor function as wild-type p53. |
2015-06-09 |
2023-08-13 |
human |
| Yong Qin, Zhenhua Ma, Xiaoyan Dang, Wei Li, Qingyong M. Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway. Molecular medicine reports. vol 10. issue 5. 2015-06-09. PMID:25190613. |
cell proliferation was assessed by the mtt assay, and apoptosis was detected by flow cytometry. |
2015-06-09 |
2023-08-13 |
human |
| Wei Zuo, Zhen-Zhong Wang, Jun Xu. Artesunate induces apoptosis of bladder cancer cells by miR-16 regulation of COX-2 expression. International journal of molecular sciences. vol 15. issue 8. 2015-06-05. PMID:25196524. |
the effect of art on growth inhibition and apoptosis of bladder cancer cells was evaluated using dimethylthiazoly-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry analysis, respectively. |
2015-06-05 |
2023-08-13 |
human |
| Fei-Fei Han, Liang Li, Bo-Yang Shang, Rong-Guang Shao, Yong-Su Zhe. Hsp90 inhibitor geldanamycin enhances the antitumor efficacy of enediyne lidamycin in association with reduced DNA damage repair. Asian Pacific journal of cancer prevention : APJCP. vol 15. issue 17. 2015-06-05. PMID:25227788. |
to investigate the potentiation of antitumor efficacy of lidamycin (ldm), an enediyne agent by the hsp90 inhibitor geldanamycin (gdm), and possible mechanisms, we have determined effects on ovarian cancer skov- 3, hepatoma bel-7402 and hepg2 cells by mtt assay, apoptosis assay, and cell cycle analysis. |
2015-06-05 |
2023-08-13 |
Not clear |
| Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Liu, Fei Xiong, Siwang Wan. Expression of BAG-1 is closely related to cell differentiation and TNM stage in esophageal cancer and its downregulation inhibits the proliferation and invasion of human esophageal carcinoma cells. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25069471. |
mtt and transwell assays were used to study cell proliferation and invasive activity, and the apoptosis rate was assessed by flow cytometry. |
2015-06-01 |
2023-08-13 |
human |
| Xu-Hui Zhou, Chao-Qun Yang, Cheng-Lin Zhang, Yang Gao, Hong-Bin Yuan, Ce Wan. RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25109282. |
a gain-of-function approach was used to observe the effects of lentiviral vector-mediated overexpression of rassf5 (lv-rassf5) on cell growth, invasion and apoptosis, respectively, as indicated by mtt, transwell and flow cytometry assays, and the expression levels of mammalian sterile 20-like (mst1) kinase, large tumor suppressor 1 (lats1), proliferating cell nuclear antigen (pcna), matrix metallopeptidase-9 (mmp-9) and p53 were detected by real-time pcr and western blot assays in os cells (mg-63 and u-2 os). |
2015-06-01 |
2023-08-13 |
human |
| Xing Ai, Zhuomin Jia, Shuanglin Liu, Jiajun Wang, Xu Zhan. Notch-1 regulates proliferation and differentiation of human bladder cancer cell lines by inhibiting expression of Krüppel-like factor 4. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25109409. |
cell proliferation, apoptosis and expression of notch-1 and klf4 were assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry assay with annexin v-fitc/pi staining, and reverse transcriptase polymerase chain reaction (rt-pcr) and western blot analysis, respectively. |
2015-06-01 |
2023-08-13 |
human |
| Morteza Eskandani, Jalal Abdolalizadeh, Hamed Hamishehkar, Hossein Nazemiyeh, Jaleh Bara. Galbanic acid inhibits HIF-1α expression via EGFR/HIF-1α pathway in cancer cells. Fitoterapia. vol 101. 2015-05-29. PMID:25510323. |
mtt survival and annexin v assays were used to evaluate gba cytotoxicity and apoptosis in treated cells. |
2015-05-29 |
2023-08-13 |
human |
| Zhi-Dong Lv, Xiang-Ping Liu, Wei-Jun Zhao, Qian Dong, Fu-Nian Li, Hai-Bo Wang, Bin Kon. Curcumin induces apoptosis in breast cancer cells and inhibits tumor growth in vitro and in vivo. International journal of clinical and experimental pathology. vol 7. issue 6. 2015-05-26. PMID:25031701. |
the mtt assay was used to evaluate cell viability, and flow cytometry, acridine orange staining and transmission electron microscopy were used to detect apoptosis for cultured cells. |
2015-05-26 |
2023-08-13 |
mouse |
| D Italibi Uraga-Tovar, M Lilia Domínguez-López, Ruth L Madera-Sandoval, Minerva Nájera-Martínez, Ethel García-Latorre, Armando Vega-Lópe. Generation of oxyradicals (O2. and H2O2), mitochondrial activity and induction of apoptosis of PBMC of Cyprinus carpio carpio treated in vivo with halomethanes and with recombinant HSP60 kDa and with LPS of Klebsiella pneumoniae. Immunopharmacology and immunotoxicology. vol 36. issue 5. 2015-05-26. PMID:25093392. |
in the current study, we evaluated the mitochondrial activity (ma) by mtt, induction of apoptosis by subg0 technique and quantified serum ros concentration (o2. |
2015-05-26 |
2023-08-13 |
Not clear |
| Jiandong Wang, Xiaoli Ma, Hannah M Jones, Leo Li-Ying Chan, Fang Song, Weiyuan Zhang, Victoria L Bae-Jump, Chunxiao Zho. Evaluation of the antitumor effects of c-Myc-Max heterodimerization inhibitor 100258-F4 in ovarian cancer cells. Journal of translational medicine. vol 12. 2015-05-26. PMID:25143136. |
using mtt assay, colony formation, flow cytometry and annexin v fitc assays, we found that 10058-f4 significantly inhibited cell proliferation of both skov3 and hey ovarian cancer cells in a dose dependent manner through induction of apoptosis and cell cycle g1 arrest. |
2015-05-26 |
2023-08-13 |
Not clear |
| Ki Hwan Kweon, Cho Rok Lee, Soo Jung Jung, Eun Jeong Ban, Sang-Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Young Suk Jo, Jandee Lee, Woong Youn Chun. Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers. International journal of oncology. vol 45. issue 5. 2015-05-25. PMID:25109285. |
tpc1, ftc133 and fro cells were used for molecular biological experiments including apoptosis assays, mtt, immunofluorescence staining and qrt-pcr assays. |
2015-05-25 |
2023-08-13 |
human |
| Xue-Wen Liu, En-Fei Ji, Peng He, Rui-Xian Xing, Bu-Xian Tian, Xi-Dong L. Protective effects of the p38 MAPK inhibitor SB203580 on NMDA‑induced injury in primary cerebral cortical neurons. Molecular medicine reports. vol 10. issue 4. 2015-05-22. PMID:25051190. |
the lactate dehydrogenase (ldh) and mtt assays were employed to investigate the effects of the drugs on apoptosis. |
2015-05-22 |
2023-08-13 |
Not clear |
| Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Li. siRNA‑induced ABCE1 silencing inhibits proliferation and invasion of breast cancer cells. Molecular medicine reports. vol 10. issue 4. 2015-05-22. PMID:25070080. |
the effect of abce1 knockdown on cell proliferation, invasion, apoptosis and gene expression was then assessed using mtt assay, transwell migration assay, flow cytometry and western blot analysis, respectively. |
2015-05-22 |
2023-08-13 |
human |