| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu hong Jing, Yi ping Hou, Yan feng Song, Jie Yi. Methylprednisolone improves the survival of new neurons following transient cerebral ischemia in rats. Acta neurobiologiae experimentalis. vol 72. issue 3. 2013-11-19. PMID:23093011. |
these results indicate that early mp administration can improve the neurological deficit and enhance the survival of new neurons in the ipsilateral striatum by inhibiting apoptosis and downregulation of inflammatory response after transient cerebral ischemia in rats. |
2013-11-19 |
2023-08-12 |
rat |
| Yu Hirano, Keiko Kowata, Mikie Kodama, Yasuo Komats. Development of a scanning electrochemical microscopy-based micropipette and its application to analysis of topographic change of single-cell. Bioelectrochemistry (Amsterdam, Netherlands). vol 92. 2013-10-25. PMID:23466409. |
cellular responses induced by mp delivery could be monitored by the secm, and cell apoptosis was successfully detected by adding a kinase inhibitor of two orders of magnitude less than what is required in the conventional method. |
2013-10-25 |
2023-08-12 |
Not clear |
| Kathryn Date, Jessica Hall, John Greenman, Anthony Maraveyas, Leigh A Madde. Tumour and microparticle tissue factor expression and cancer thrombosis. Thrombosis research. vol 131. issue 2. 2013-09-19. PMID:23237339. |
chemotherapy may, in eliciting cancer cell apoptosis, result in an increase in release of circulating procoagulant mp. |
2013-09-19 |
2023-08-12 |
Not clear |
| R Lacroix, C Judicone, P Poncelet, S Robert, L Arnaud, J Sampol, F Dignat-Georg. Impact of pre-analytical parameters on the measurement of circulating microparticles: towards standardization of protocol. Journal of thrombosis and haemostasis : JTH. vol 10. issue 3. 2013-07-08. PMID:22212198. |
microparticles (mp) are small vesicles of 0.1-1 μm, released in response to activation or apoptosis. |
2013-07-08 |
2023-08-12 |
Not clear |
| I V Mindukshev, N I Rukoiatkina, I A Dobrylko, E A Skverchinskaia, E R Nikitina, V V Krivoshlyk, S P Gambarian, A I Krivchenk. [Characterisation of enucleated cells apoptosis: human platelets and erythrocytes]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 99. issue 1. 2013-06-18. PMID:23659060. |
induction of platelet apoptosis by both methods (t/c and abt-373) lead to strong phosphoetydilserine (ps) externalization, loss of the mitochondrial membrane potential (deltapsim), proteolytic cleavage of some cytoskeletal and regulatory proteins, and microparticle (mp) formation. |
2013-06-18 |
2023-08-12 |
human |
| I V Mindukshev, N I Rukoiatkina, I A Dobrylko, E A Skverchinskaia, E R Nikitina, V V Krivoshlyk, S P Gambarian, A I Krivchenk. [Characterisation of enucleated cells apoptosis: human platelets and erythrocytes]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 99. issue 1. 2013-06-18. PMID:23659060. |
erythrocytes apoptosis induced by tbh is characterized by formation ofmethb, cell shrinkage, fast (95 % during 3 hours) ps externalization, yield of hemoglobin, probably by vesicle (mp) formation. |
2013-06-18 |
2023-08-12 |
human |
| David Varon, Yael Hayon, Olga Dashevsky, Ela Sha. Involvement of platelet derived microparticles in tumor metastasis and tissue regeneration. Thrombosis research. vol 130 Suppl 1. 2013-05-20. PMID:23026678. |
microparticles (mp) are small plasma membrane vesicles shed from cells upon their activation or apoptosis. |
2013-05-20 |
2023-08-12 |
Not clear |
| Burçin Tezcanli Kaymaz, Nur Selvi, Güray Saydam, Fahri Sahin, Buket Kosov. Methylprednisolone induces apoptosis by interacting with the JAK/STAT pathway in HL-60 and K-562 leukemic cells. Hematology (Amsterdam, Netherlands). vol 17. issue 2. 2012-12-14. PMID:22664047. |
to determine the gene expression profiles of the jak/stat pathway members stat3, stat5a, stat5b at both mrna and protein levels in hl-60 and k-562 leukemia cells that were undergoing apoptosis following high-dose methylprednisolone (mp) treatment. |
2012-12-14 |
2023-08-12 |
Not clear |
| Jean-Michel Pontier, Emmanuel Gempp, Mihaela Ignatesc. Blood platelet-derived microparticles release and bubble formation after an open-sea air dive. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 37. issue 5. 2012-10-16. PMID:22735037. |
endothelial cells, blood platelets, or leukocytes shed microparticles (mp) upon activation and during cell apoptosis. |
2012-10-16 |
2023-08-12 |
rat |
| X-M Jing, Y-J Wen, W Shi, Q-Q Tang, J Li, X-C Che. VSV-MP gene therapy strategy inhibits tumor growth in nude mice model of human lung adenocarcinoma. Cancer gene therapy. vol 19. issue 2. 2012-08-16. PMID:22052213. |
vesicular stomatitis virus (vsv) matrix protein (mp) can induce in vitro apoptosis of tumor cells in the absence of other viral components. |
2012-08-16 |
2023-08-12 |
mouse |
| C M de Carvalho, P F C Menezes, G C Letenski, C E O Praes, I H S Feferman, M Lorencin. In vitro induction of apoptosis, necrosis and genotoxicity by cosmetic preservatives: application of flow cytometry as a complementary analysis by NRU. International journal of cosmetic science. vol 34. issue 2. 2012-07-09. PMID:22118339. |
the purpose of this study was to investigate and compare the in vitro apoptosis, necrosis and genotoxicity-inducing potential of five different types of preservatives: phenoxyethanol (pe), propylparaben (pp), methylparaben (mp), benzyl alcohol (ba) and ethylhexyl glycerine (eg). |
2012-07-09 |
2023-08-12 |
human |
| C M de Carvalho, P F C Menezes, G C Letenski, C E O Praes, I H S Feferman, M Lorencin. In vitro induction of apoptosis, necrosis and genotoxicity by cosmetic preservatives: application of flow cytometry as a complementary analysis by NRU. International journal of cosmetic science. vol 34. issue 2. 2012-07-09. PMID:22118339. |
our results showed that pe, pp, mp and ba have similar cytotoxic mechanisms (high apoptosis and necrosis levels only at the test concentration of 1%), whereas eg showed only an apoptosis pathway. |
2012-07-09 |
2023-08-12 |
human |
| William H Goodson, Maria Gloria Luciani, S Aejaz Sayeed, Ian M Jaffee, Dan H Moore, Shanaz H Dairke. Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women. Carcinogenesis. vol 32. issue 11. 2011-12-22. PMID:21890461. |
moreover, hrbecs pretreated with bpa, or the xe, methylparaben (mp), surmounted antiestrogenic effects of tamoxifen showing dose-dependent apoptosis evasion and induction of cell cycling. |
2011-12-22 |
2023-08-12 |
human |
| Awadh B Yadav, Pavan Muttil, Amit K Singh, Rahul K Verma, Mradul Mohan, Atul K Agrawal, Ajay S Verma, Sudhir K Sinha, Amit Misr. Microparticles induce variable levels of activation in macrophages infected with Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). vol 90. issue 3. 2011-11-21. PMID:20382085. |
about 19% of infected cells exposed to mp underwent apoptosis compared to approximately 11% cells treated otherwise. |
2011-11-21 |
2023-08-12 |
mouse |
| Xin Chen, Bin Zhang, Yan Chai, Bo Dong, Ping Lei, Rongcai Jiang, Jianning Zhan. Methylprednisolone exacerbates acute critical illness-related corticosteroid insufficiency associated with traumatic brain injury in rats. Brain research. vol 1382. 2011-11-15. PMID:21262204. |
the purpose of this study was to test the hypothesis that methylprednisolone (mp), a synthetic glucocorticoid, promotes post-traumatic apoptosis in both the hypothalamus and pituitary, resulting in acute circi and increased mortality in the acute phase of traumatic brain injury (tbi). |
2011-11-15 |
2023-08-12 |
rat |
| Xin Chen, Bin Zhang, Yan Chai, Bo Dong, Ping Lei, Rongcai Jiang, Jianning Zhan. Methylprednisolone exacerbates acute critical illness-related corticosteroid insufficiency associated with traumatic brain injury in rats. Brain research. vol 1382. 2011-11-15. PMID:21262204. |
moreover, tem revealed morphological changes characteristic of apoptosis in both the pvn and adenohypophysis of high-dose mp treated rats. |
2011-11-15 |
2023-08-12 |
rat |
| Xin Chen, Bin Zhang, Yan Chai, Bo Dong, Ping Lei, Rongcai Jiang, Jianning Zhan. Methylprednisolone exacerbates acute critical illness-related corticosteroid insufficiency associated with traumatic brain injury in rats. Brain research. vol 1382. 2011-11-15. PMID:21262204. |
these data suggest that mp therapy for tbi could increase neuronal apoptosis in both the hypothalamus and pituitary and consequently exacerbate acute circi and mortality induced by tbi. |
2011-11-15 |
2023-08-12 |
rat |
| T Neri, C Armani, A Pegoli, C Cordazzo, Y Carmazzi, S Brunelleschi, C Bardelli, M C Breschi, P Paggiaro, A Cel. Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles. The European respiratory journal. vol 37. issue 6. 2011-10-07. PMID:21148223. |
microparticles (mp) are phospholipid vesicles shed by cells upon activation or apoptosis. |
2011-10-07 |
2023-08-12 |
human |
| Thang Q Hoang, Christine Rampon, Jean-Marie Freyssinet, Sophie Vriz, Danièle Kerbiriou-Nabia. A method to assess the migration properties of cell-derived microparticles within a living tissue. Biochimica et biophysica acta. vol 1810. issue 9. 2011-09-19. PMID:21609754. |
cells undergoing activation or apoptosis exhibit plasma membrane changes, leading to the formation of shed vesicles (microparticles, mp). |
2011-09-19 |
2023-08-12 |
Not clear |
| Yun Mi Kang, Gyeong Hae Kim, Jae Il Kim, Da Yeon Kim, Bit Na Lee, So Mi Yoon, Jae Ho Kim, Moon Suk Ki. In vivo efficacy of an intratumorally injected in situ-forming doxorubicin/poly(ethylene glycol)-b-polycaprolactone diblock copolymer. Biomaterials. vol 32. issue 20. 2011-08-22. PMID:21440935. |
consistent with the observed suppression of tumor growth, intratumorally injected free dox or dox released from dox-loaded mp gels caused apoptosis of tumor cells. |
2011-08-22 |
2023-08-12 |
mouse |