| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Madhu Bhaskaran, Aditi A Kapasi, Krishna Reddy, Pravin C Singha. Morphine priming rescues high-dose morphine-induced biological perturbations. The Journal of infectious diseases. vol 195. issue 12. 2007-07-10. PMID:17492603. |
in in vitro studies, macrophages and bone-marrow cells harvested from hdm-treated mice showed not only enhanced apoptosis but also decreased migration across the filter of a boyden chamber; nevertheless, mp inhibited these effects of hdm. |
2007-07-10 |
2023-08-12 |
mouse |
| Xiaojuan Lin, Xiancheng Chen, Yuquan Wei, Jumei Zhao, Linyu Fan, Yanjun Wen, Hongbo Wu, Xia Zha. Efficient inhibition of intraperitoneal human ovarian cancer growth and prolonged survival by gene transfer of vesicular stomatitis virus matrix protein in nude mice. Gynecologic oncology. vol 104. issue 3. 2007-03-27. PMID:17112567. |
vesicular stomatitis virus (vsv) matrix protein (mp) has been reported to be capable of inducing apoptosis in vitro in the absence of other viral components. |
2007-03-27 |
2023-08-12 |
mouse |
| Chia-Ching Wu, Yi-Shuan Li, Jason H Haga, Roland Kaunas, Jeng-Jiann Chiu, Fong-Chin Su, Shunichi Usami, Shu Chie. Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 4. 2007-03-01. PMID:17229844. |
to study the roles of anisotropic cell morphology and directionality of mechanical force in apoptosis, the spreading of human umbilical vein endothelial cells (huvecs) was constrained by growing on micropatterned (mp) strips of fibronectin (fn, 20 microg/cm2) with widths of 15, 30, and 60 microm on silicone membrane. |
2007-03-01 |
2023-08-12 |
human |
| Olivier Morel, Florence Toti, Babé Bakouboula, Lélia Grunebaum, Jean-Marie Freyssine. Procoagulant microparticles: 'criminal partners' in atherothrombosis and deleterious cellular exchanges. Pathophysiology of haemostasis and thrombosis. vol 35. issue 1-2. 2006-09-22. PMID:16855341. |
besides this procoagulant potential, trapped mp could contribute to plaque vulnerability through multiple pathways including angiogenesis, extracellular matrix proteolysis, recruitment of inflammatory cells, smooth muscle cell and endothelial apoptosis. |
2006-09-22 |
2023-08-12 |
human |
| Chiara Cerri, Daniele Chimenti, Ilaria Conti, Tommaso Neri, Pierluigi Paggiaro, Alessandro Cel. Monocyte/macrophage-derived microparticles up-regulate inflammatory mediator synthesis by human airway epithelial cells. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 3. 2006-09-06. PMID:16849511. |
cell-derived microparticles (mp) are membrane fragments shed by virtually all eukaryotic cells upon activation or during apoptosis that play a significant role in physiologically relevant processes, including coagulation and inflammation. |
2006-09-06 |
2023-08-12 |
human |
| J Vaquero, M Zurita, S Oya, C Aguayo, C Bonill. Early administration of methylprednisolone decreases apoptotic cell death after spinal cord injury. Histology and histopathology. vol 21. issue 10. 2006-08-04. PMID:16835831. |
the purpose of this study is to evaluate, in an experimental model of spinal cord injury (sci), the presence of apoptotic cell death after trauma and if early administration of a single bolus of methylprednisolone (mp) influences apoptosis in the zone of trauma and in adjacent spinal cord segments. |
2006-08-04 |
2023-08-12 |
rat |
| Cristina Banfi, Maura Brioschi, Robin Wait, Shajna Begum, Elisabetta Gianazza, Angela Pirillo, Luciana Mussoni, Elena Tremol. Proteome of endothelial cell-derived procoagulant microparticles. Proteomics. vol 5. issue 17. 2006-03-27. PMID:16220532. |
microparticles (mp) are small membrane vesicles that are released from cells upon activation or during apoptosis. |
2006-03-27 |
2023-08-12 |
Not clear |
| J C Panetta, W E Evans, M H Cheo. Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells. British journal of cancer. vol 94. issue 1. 2006-02-16. PMID:16333308. |
to study the dynamics of mp on the cell cycle, we incubated human t-cell leukaemia cell lines (molt-4 sensitive and resistant subline and p12 resistant) with 10 microm mp and measured total cell count, cell cycle distribution, percent viable, percent apoptotic, and percent dead cells serially over 72 h. we developed a mathematical model of the cell cycle dynamics after treatment with mp and used it to show that the molt-4 sensitive controls had a significantly higher rate of cells entering apoptosis (2.7-fold, p<0.00001) relative to the resistant cell lines. |
2006-02-16 |
2023-08-12 |
human |
| J C Panetta, W E Evans, M H Cheo. Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells. British journal of cancer. vol 94. issue 1. 2006-02-16. PMID:16333308. |
additionally, when treated with mp, the sensitive cell line showed a significant increase in the rate at which cells enter apoptosis compared to its controls (2.4-fold, p<0.00001). |
2006-02-16 |
2023-08-12 |
human |
| Yeevoon Ng, Rola Barhoumi, Ronald B Tjalkens, Yang-Yi Fan, Satya Kolar, Naisyin Wang, Joanne R Lupton, Robert S Chapki. The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. Carcinogenesis. vol 26. issue 11. 2005-12-13. PMID:15975958. |
these data indicate that dha and butyrate potentiate mitochondrial lipid oxidation and the dissipation of mp which contribute to the induction of apoptosis. |
2005-12-13 |
2023-08-12 |
mouse |
| Stephan Schubert, Gisela Stoltenburg-Didinger, Anke Wehsack, Dirk Troitzsch, Wolfgang Boettcher, Michael Huebler, Matthias Redlin, Majid Kanaan, Michael Meissler, Peter E Lange, Hashim Abdul-Khali. Large-dose pretreatment with methylprednisolone fails to attenuate neuronal injury after deep hypothermic circulatory arrest in a neonatal piglet model. Anesthesia and analgesia. vol 101. issue 5. 2005-11-22. PMID:16243986. |
in comparison to the control group, large-dose pretreatment with systemic mp lead to an increase of necrotic neuronal cell death and induced significant neuronal apoptosis in the dentate gyrus of the hippocampus (p = 0.001). |
2005-11-22 |
2023-08-12 |
Not clear |
| Stephan Schubert, Gisela Stoltenburg-Didinger, Anke Wehsack, Dirk Troitzsch, Wolfgang Boettcher, Michael Huebler, Matthias Redlin, Majid Kanaan, Michael Meissler, Peter E Lange, Hashim Abdul-Khali. Large-dose pretreatment with methylprednisolone fails to attenuate neuronal injury after deep hypothermic circulatory arrest in a neonatal piglet model. Anesthesia and analgesia. vol 101. issue 5. 2005-11-22. PMID:16243986. |
in conclusion, systemic pretreatment with large-dose mp fails to attenuate neuronal cell injury after prolonged dhca and induces regional neuronal apoptosis in the dentate gyrus. |
2005-11-22 |
2023-08-12 |
Not clear |
| A Pawlik, M Baskiewicz-Masiuk, B Machalinski, B Gawronska-Szklar. Involvement of P-gp in the process of apoptosis in peripheral blood mononuclear cells. International immunopharmacology. vol 5. issue 5. 2005-09-01. PMID:15778118. |
the aim of the study was to evaluate the effect of p-gp inhibition on apoptosis of pha-activated peripheral blood mononuclear cells (mnc) as well as apoptosis induced by methotrexate (mtx), dexamethasone (dex), methylprednisolone (mp) and cortisone (cor). |
2005-09-01 |
2023-08-12 |
Not clear |
| A Pawlik, M Baskiewicz-Masiuk, B Machalinski, B Gawronska-Szklar. Involvement of P-gp in the process of apoptosis in peripheral blood mononuclear cells. International immunopharmacology. vol 5. issue 5. 2005-09-01. PMID:15778118. |
moreover these agents significantly increased the apoptosis induced by mtx, dex, mp and cor. |
2005-09-01 |
2023-08-12 |
Not clear |
| M N Abid Hussein, R Nieuwland, C M Hau, L M Evers, E W Meesters, A Stur. Cell-derived microparticles contain caspase 3 in vitro and in vivo. Journal of thrombosis and haemostasis : JTH. vol 3. issue 5. 2005-08-19. PMID:15869582. |
microparticles (mp) from endothelial cells (endothelial microparticles; emp) circulate in disease states, but the processes such as apoptosis or cell activation underlying their release are unclear. |
2005-08-19 |
2023-08-12 |
Not clear |
| Xinyuan Zhang, Gaetano Barile, Stanley Chang, Arthur Hays, Sophia Pachydaki, William Schiff, Janet Sparro. Apoptosis and cell proliferation in proliferative retinal disorders: PCNA, Ki-67, caspase-3, and PARP expression. Current eye research. vol 30. issue 5. 2005-08-16. PMID:16020270. |
to assess the incidence of cell proliferation and apoptosis in epiretinal membranes from eyes with proliferative vitreoretinopathy (pvr), proliferative diabetic retinopathy (pdr), and macular pucker (mp) and to further investigate the potential involvement of key executors of apoptosis. |
2005-08-16 |
2023-08-12 |
Not clear |
| O Morel, B Hugel, L Jesel, F Zobairi, P Bareiss, J M Freyssinet, F Tot. [Procoagulant membranous microparticles and atherothrombotic complications in diabetics]. Archives des maladies du coeur et des vaisseaux. vol 97. issue 10. 2005-07-29. PMID:16008179. |
mp are one of the key factors linking inflammation, oxidative stress, apoptosis and thrombosis in accelerated atherothrombotic disease of the diabetic. |
2005-07-29 |
2023-08-12 |
Not clear |
| Anja Trapp, Michael Wei. The impact of immunosuppression on endothelial function. Journal of cardiovascular pharmacology. vol 45. issue 1. 2005-06-15. PMID:15613984. |
we examined human microvascular endothelial cells (hmec-1) in vitro after stimulation with therapeutic concentrations of methylprednisolone (mp), mycophenolic acid (mmf), cyclosporine a (cs), rapamycin (rapa), and tacrolimus (tac) to designate the corresponding induction of oxidative stress, apoptosis, metabolic activity, proliferation, endothelin (et-1) release, and nitric oxide (no) production. |
2005-06-15 |
2023-08-12 |
human |
| Yanjuan Sheng, Yu Zhu, Lezheng W. Effect of high dosage of methylprednisolone on rat retinal ganglion cell apoptosis after optic nerve crush. Yan ke xue bao = Eye science. vol 20. issue 3. 2005-03-29. PMID:15499728. |
to investigate the effect of high dose methylprednisolone (mp) on retinal ganglion cells (rgc) apoptosis. |
2005-03-29 |
2023-08-12 |
rat |
| Olivier Morel, Bénédicte Hugel, Laurence Jesel, François Lanza, Marie-Pierre Douchet, Michel Zupan, Michel Chauvin, Jean-Pierre Cazenave, Jean-Marie Freyssinet, Florence Tot. Sustained elevated amounts of circulating procoagulant membrane microparticles and soluble GPV after acute myocardial infarction in diabetes mellitus. Thrombosis and haemostasis. vol 91. issue 2. 2004-10-19. PMID:14961163. |
during myocardial infarction (mi), platelet activation and endothelial apoptosis are responsible for the release of procoagulant membrane-derived microparticles (mp) in the blood flow. |
2004-10-19 |
2023-08-12 |
human |