| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M F Iakushev, S V Boĭchuk, A A Vizel', G N Sadykov. [A comparative study of lymphocytic apoptosis and ventilation disorders in patients with pulmonary tuberculosis]. Problemy tuberkuleza i boleznei legkikh. issue 5. 2004-10-08. PMID:15230197. |
the apoptosis was evaluated in dynamics by some parameters: the change of the mitochondrial potential (mp), the level of phosphatidyl serine, as well as dna fragmentation by flow cytofluorometry. |
2004-10-08 |
2023-08-12 |
Not clear |
| M F Iakushev, S V Boĭchuk, A A Vizel', G N Sadykov. [A comparative study of lymphocytic apoptosis and ventilation disorders in patients with pulmonary tuberculosis]. Problemy tuberkuleza i boleznei legkikh. issue 5. 2004-10-08. PMID:15230197. |
the factor associating the degree of obstruction, with the count of mc540(+)- and mc540-dioc6(+)-lymphocytes, i.e., with the count of lymphocytes with cellular membranous changes and with the decreased mp, which are one of the most significant signs of apoptosis. |
2004-10-08 |
2023-08-12 |
Not clear |
| Sylvain Baize, Jérôme Kaplon, Caroline Faure, Delphine Pannetier, Marie-Claude Georges-Courbot, Vincent Deube. Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 5. 2004-06-21. PMID:14978087. |
lv did not induce apoptosis in dc and mp. |
2004-06-21 |
2023-08-12 |
human |
| J Zheng, M R Thylin, Y Persidsky, C E Williams, R L Cotter, W Zink, L Ryan, A Ghorpade, K Lewis, H E Gendelma. HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise. Neurotoxicity research. vol 3. issue 5. 2004-03-23. PMID:14715459. |
the upregulation of nmda receptor sensitive soluble factors and neuronal apoptosis by hiv-1-infected and immune-activated mdm provide unique insights into links between soluble factors, produced as a consequence of mp immunity, and neuronal demise in had. |
2004-03-23 |
2023-08-12 |
human |
| Vu Thuong Nguyen, Juan Arredondo, Alexander I Chernyavsky, Yasuo Kitajima, Mark Pittelkow, Sergei A Grand. Pemphigus vulgaris IgG and methylprednisolone exhibit reciprocal effects on keratinocytes. The Journal of biological chemistry. vol 279. issue 3. 2004-02-12. PMID:14600150. |
the use of dna microarray showed that pv igg down-regulated and mp up-regulated expression of the genes encoding keratinocyte adhesion molecules, antigen-processing proteins, regulators of cell cycle and apoptosis, differentiation markers, na+,k+-atpase, protein kinases and phosphatases, and serine proteases and their inhibitors. |
2004-02-12 |
2023-08-12 |
mouse |
| Bénédicte Chazaud, Corinne Sonnet, Peggy Lafuste, Guillaume Bassez, Anne-Cécile Rimaniol, Françoise Poron, François-Jerome Authier, Patrick A Dreyfus, Romain K Gherard. Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth. The Journal of cell biology. vol 163. issue 5. 2004-02-03. PMID:14662751. |
determination of [3h]thymidine incorporation, oligosomal dna levels and annexin-v binding showed that mp stimulate mpc proliferation by soluble factors, and rescue mpc from apoptosis by direct contacts. |
2004-02-03 |
2023-08-12 |
human |
| Takuzo Fujiwara, Yoshihiro Ikeda, Kayo Arita, Tomoko Kanno, Yoshiki Takehara, Munehisa Yabuki, Kozo Utsum. The effects of immunosuppressants on FAS-mediated activation-induced cell death in human T lymphocytes. Transplant international : official journal of the European Society for Organ Transplantation. vol 16. issue 2. 2003-10-20. PMID:12595972. |
in the death phase, mp induced apoptosis without 7c11 and csa had no effects. |
2003-10-20 |
2023-08-12 |
human |
| Jens Schmidt, Josbert M Metselaar, Marca H M Wauben, Klaus V Toyka, Gert Storm, Ralf Gol. Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. Brain : a journal of neurology. vol 126. issue Pt 8. 2003-09-16. PMID:12805101. |
pl was also superior to mp in diminishing t-cell infiltration by induction of t-cell apoptosis in spinal cord. |
2003-09-16 |
2023-08-12 |
rat |
| Andrew Chan, Christina Papadimitriou, Wolfgang Graf, Klaus V Toyka, Ralf Gol. Effects of polyclonal immunoglobulins and other immunomodulatory agents on microglial phagocytosis of apoptotic inflammatory T-cells. Journal of neuroimmunology. vol 135. issue 1-2. 2003-03-20. PMID:12576237. |
glatiramer acetate (glat) did not exert an effect on microglial phagocytosis, while methylprednisolone (mp) induced microglial apoptosis in vitro. |
2003-03-20 |
2023-08-12 |
rat |
| Pauline G Knox, Anne E Milner, Nicky K Green, Aristides G Eliopoulos, Lawrence S Youn. Inhibition of metalloproteinase cleavage enhances the cytotoxicity of Fas ligand. Journal of immunology (Baltimore, Md. : 1950). vol 170. issue 2. 2003-03-04. PMID:12517928. |
blockade of fasl cleavage with an mp inhibitor significantly enhanced radfasl-induced apoptosis suggesting that sfasl may antagonize the effect of membrane-bound fasl. |
2003-03-04 |
2023-08-12 |
Not clear |
| O Kolek, B Gajkowska, M M Godlewski, T Moty. Molecular mechanism of TGF-beta1-induced apoptosis in HC11 mouse mammary epithelial cells (MEC). Cellular and molecular biology (Noisy-le-Grand, France). vol 47 Online Pub. 2002-10-04. PMID:11936868. |
apoptosis induced by tgf-beta1 (2 ng/ml) was associated with the increase of bax mp observed within 60 min. |
2002-10-04 |
2023-08-12 |
mouse |
| Tim Magnus, Andrew Chan, Ralf A Linker, Klaus V Toyka, Ralf Gol. Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system. Journal of neuropathology and experimental neurology. vol 61. issue 9. 2002-09-23. PMID:12230322. |
apoptosis was induced in autologous thymocytes and myelin basic protein (mbp)-specific t-cells by methylprednisolone (mp) or by irradiation. |
2002-09-23 |
2023-08-12 |
human |
| J Schmidt, S Stürzebecher, K V Toyka, R Gol. Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration. Journal of neuroscience research. vol 65. issue 1. 2001-08-16. PMID:11433430. |
in severe eae, an increase of t cell apoptosis was seen after ifn-beta alone (all data presented as mean +/- sd: 24.5% +/- 2.2%, p < 0.05, vs. 19.4% +/- 3.1% in controls), and in combination with mp (29.4% +/- 7.3%, p < 0.05 vs. controls). |
2001-08-16 |
2023-08-12 |
rat |
| J Schmidt, S Stürzebecher, K V Toyka, R Gol. Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration. Journal of neuroscience research. vol 65. issue 1. 2001-08-16. PMID:11433430. |
in moderate eae, the rate of t cell apoptosis was slightly increased after ifn-beta (21.2% +/- 5.2% vs. 17.4% +/- 5.0% in controls), whereas mp alone (25.5% +/- 3.5%, p < 0.01 vs. controls) and the combination therapy (22.4% +/- 4.8%, p < 0.05 vs. controls) had a clear augmenting effect. |
2001-08-16 |
2023-08-12 |
rat |
| H Miyake, I Hara, K Gohji, S Arakawa, S Kamidon. p53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line. International journal of oncology. vol 12. issue 2. 2001-03-01. PMID:9458377. |
the anti-fas monoclonal antibody (ch11) induced apoptosis in the achn/c cells in a dose-dependent manner, whereas the effect of ch11 on the achn/ mp cells was markedly suppressed. |
2001-03-01 |
2023-08-12 |
human |
| N Tong, S W Perry, Q Zhang, H J James, H Guo, A Brooks, H Bal, S A Kinnear, S Fine, L G Epstein, D Dairaghi, T J Schall, H E Gendelman, S Dewhurst, L R Sharer, H A Gelbar. Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 3. 2000-02-24. PMID:10640747. |
hiv-1-infected mononuclear phagocytes (mp) present in inflammatory infiltrates produce neurotoxins that mediate inflammation, dysfunction, and neuronal apoptosis. |
2000-02-24 |
2023-08-12 |
human |
| N Ozbek, E Erdemli, G Hiçsönmez, H Okur, M Tekelioğl. Effects of methylprednisolone on human myeloid leukemic cells in vitro. American journal of hematology. vol 60. issue 4. 1999-04-22. PMID:10203097. |
a marked increase in mp-induced apoptosis of leukemic cells, with a maximum effect at 24 hr of exposure to both low and high concentrations of mp (10(-6) m and 10(-3) m), was demonstrated by light microscopy in cultures of four (three with aml-m1 and one with aml-m7) of the nine patients. |
1999-04-22 |
2023-08-12 |
human |
| N Ozbek, E Erdemli, G Hiçsönmez, H Okur, M Tekelioğl. Effects of methylprednisolone on human myeloid leukemic cells in vitro. American journal of hematology. vol 60. issue 4. 1999-04-22. PMID:10203097. |
the results of the present study, together with our previous clinical experience, suggest that mp, especially at high doses, could have a significant role in the treatment of some aml patients by inducing apoptosis and differentiation of leukemic cells. |
1999-04-22 |
2023-08-12 |
human |
| D Gottardi, A M De Leo, A Alfarano, A Stacchini, P Circosta, M G Gregoretti, L Bergui, M Aragno, F Caligaris-Cappi. Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells: in vitro/in vivo correlations. British journal of haematology. vol 99. issue 1. 1997-12-09. PMID:9359515. |
the amount of apoptosis was significantly higher in the samples treated with f-ara-a than in those exposed to mp alone. |
1997-12-09 |
2023-08-12 |
Not clear |
| D Gottardi, A M De Leo, A Alfarano, A Stacchini, P Circosta, M G Gregoretti, L Bergui, M Aragno, F Caligaris-Cappi. Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells: in vitro/in vivo correlations. British journal of haematology. vol 99. issue 1. 1997-12-09. PMID:9359515. |
in the seven remaining cases, no bcl-2 down-regulation was observed after exposure to f-ara-a and the degree of f-ara-a-induced apoptosis overlapped that induced by mp. |
1997-12-09 |
2023-08-12 |
Not clear |