| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhao Yin, Yizhen Huang, Yangmin Zhu, Qi Zhong, Huijuan Shen, Shaya Mahati, Jing Huang, Guangchao Li, Ruiming Ou, Zhi Liu, Qing Zhang, Shuang Li. Identification and analysis of microplastic aggregation in CAR-T cells. Journal of hazardous materials. vol 480. 2024-11-03. PMID:39488976. |
subsequent investigation revealed that the exposure of car-t cells to varying concentrations of mp resulted in a notable increase in apoptosis, ferroptosis, and exhaustion levels. |
2024-11-03 |
2024-11-06 |
Not clear |
| Zhao Yin, Yizhen Huang, Yangmin Zhu, Qi Zhong, Huijuan Shen, Shaya Mahati, Jing Huang, Guangchao Li, Ruiming Ou, Zhi Liu, Qing Zhang, Shuang Li. Identification and analysis of microplastic aggregation in CAR-T cells. Journal of hazardous materials. vol 480. 2024-11-03. PMID:39488976. |
mp present a threat to car-t cell function due to their role in inducing car-t cell apoptosis, ferroptosis, and t-cell exhaustion through the hyperactivation of mtor signaling pathways. |
2024-11-03 |
2024-11-06 |
Not clear |
| Zhikun Zhang, Dawei Shi, Haiwei Dou, Ruijie Wan, Qing Yuan, Peng Tu, Deli Xi. Mycoplasma pneumoniae regulates the expression of GP130 in lung epithelial cells through apoptosis and TLR4/ NF-κB pathway during infection. Microbial pathogenesis. 2024-10-24. PMID:39447660. |
gene expression analysis revealed that mp affected apoptosis and the tlr4 pathway in infected cells, and the mrna level of il-6 was correlated with that of gp130. |
2024-10-24 |
2024-10-28 |
Not clear |
| Zhikun Zhang, Dawei Shi, Haiwei Dou, Ruijie Wan, Qing Yuan, Peng Tu, Deli Xi. Mycoplasma pneumoniae regulates the expression of GP130 in lung epithelial cells through apoptosis and TLR4/ NF-κB pathway during infection. Microbial pathogenesis. 2024-10-24. PMID:39447660. |
further, z-vad-fmk (pan-caspase inhibitor) can suppress the apoptosis induced by mp infection and restore gp130 at protein level. |
2024-10-24 |
2024-10-28 |
Not clear |
| Zhikun Zhang, Dawei Shi, Haiwei Dou, Ruijie Wan, Qing Yuan, Peng Tu, Deli Xi. Mycoplasma pneumoniae regulates the expression of GP130 in lung epithelial cells through apoptosis and TLR4/ NF-κB pathway during infection. Microbial pathogenesis. 2024-10-24. PMID:39447660. |
these suggested that the regulation of tlr4/nf-κb pathway and induced apoptosis post mp infection are involved in the down-regulation of gp130 at transcription and protein levels, respectively. |
2024-10-24 |
2024-10-28 |
Not clear |
| Maryam Mohajer, Azadeh Asefnejad, Seyed Behnamedin Jameie, Mehdi Khanmohammadi, Sajad Hassanzade. Effectiveness of Insolubilized Poly(vinyl alcohol)-Based Electrospun Fiber-Loaded Methylprednisolone by Enzyme-Catalyzed Cross-Linking in a Rat Spinal Cord Injury Model. ACS applied bio materials. 2024-10-22. PMID:39436827. |
the mp-loaded pvaph/gelaph mat developed through the long-term release of mp and the biocompatible fabricated mat could inhibit axonal demyelination, attenuate apoptosis, and improve the functional outcome, which verified the potential of pvaph/gelaph + mp nanocomposites as a bioactive scaffold for sci regeneration. |
2024-10-22 |
2024-10-25 |
rat |
| Moyong Xue, Ming Jia, Yuchang Qin, Frédéric Francis, Xu G. Toxicity of parental co-exposure of microplastic and bisphenol compounds on adult zebrafish: Multi-omics investigations on offspring. The Science of the total environment. 2024-10-14. PMID:39401590. |
transcriptomics and metabolomics further showed single or co-exposure of bisphenol compounds and mp could together regulate apoptosis, calcium signaling pathway and glycerophospholipid signaling pathways. |
2024-10-14 |
2024-10-17 |
zebrafish |
| Seok-Man Kim, Yong-Hee Kim, Gil Un Han, Seul Gi Kim, Bang-Jin Kim, Sung-Hwan Moon, Seung Hee Shin, Buom-Yong Ry. Elucidating the mechanisms and mitigation strategies for six-phthalate-induced toxicity in male germ cells. Frontiers in cell and developmental biology. vol 12. 2024-07-26. PMID:39050888. |
treatment with 25 μg/ml mp significantly induced reactive oxygen species generation and promoted apoptosis. |
2024-07-26 |
2024-07-28 |
Not clear |
| Yi Zhou, Yongzhong Li, Jing Chen, Kai Mei, Mingxiang Kang, Ping Chen, Qiu L. Matrix protein of vesicular stomatitis virus targets the mitochondria, reprograms glucose metabolism，and sensitizes to 2-deoxyglucose in glioblastoma. Human gene therapy. 2024-07-13. PMID:39001830. |
when combined with 2-dg, vsv mp synergistically aggravated cell viability, apoptosis and g2/m phase arrest. |
2024-07-13 |
2024-07-16 |
Not clear |
| Wei Zhao, Zhenshan Jia, William A Bauman, Yiwen Qin, Yuanzhen Peng, Zihao Chen, Christopher P Cardozo, Dong Wang, Weiping Qi. Targeted-delivery of nanomedicine-enabled methylprednisolone to injured spinal cord promotes neuroprotection and functional recovery after acute spinal cord injury in rats. Nanomedicine : nanotechnology, biology, and medicine. 2024-06-13. PMID:38871068. |
our in vivo data reveal that nano-mp is significantly more effective than free mp in attenuating secondary injuries and neuronal apoptosis. |
2024-06-13 |
2024-06-16 |
human |
| Qian Wu, Rui Li, Yifei You, Wei Cheng, Yan Li, Yan Feng, Yuqin Fan, Yan Wan. Lung microbiota participated in fibrous microplastics (MPs) aggravating OVA-induced asthma disease in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-06-08. PMID:38851522. |
in addition, mp fibers exposure induced lung epithelial cells apoptosis, disruption of epithelial barrier integrity and activation of nlrp3 related signaling pathways. |
2024-06-08 |
2024-06-11 |
mouse |
| Yaru Huang, Wenying Chi, Yan Li, Chengzhen Zhang, Junfa Li, Fanjun Men. Morphine Preconditioning Alleviates Ischemia/Reperfusion-induced Caspase-8-dependent Neuronal Apoptosis through cPKCγ-NF-κB-cFLIPL Pathway. Journal of neurosurgical anesthesiology. 2024-04-05. PMID:38577840. |
however, the mechanism of mp on the ischemia/reperfusion-induced neuronal apoptosis has not been fully clarified. |
2024-04-05 |
2024-04-07 |
Not clear |
| Wencan Zhang, Mingshan Liu, Jie Ren, Shuwei Han, Xiaolong Zhou, Dapeng Zhang, Xianzheng Guo, Haiwen Feng, Lei Ye, Shiqing Feng, Xizi Song, Lin Jin, Zhijian We. Magnetic Nanoparticles and Methylprednisolone Based Physico-Chemical Bifunctional Neural Stem Cells Delivery System for Spinal Cord Injury Repair. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-03-22. PMID:38516757. |
the delivery system releases mp to promote microglial m2 polarization, inhibit m1 polarization, and reduce neuronal apoptosis. |
2024-03-22 |
2024-03-24 |
mouse |
| Sasha Coates-Park, Joshua A Rich, William G Stetler-Stevenson, David Peene. The TIMP protein family: diverse roles in pathophysiology. American journal of physiology. Cell physiology. vol 326. issue 3. 2024-03-05. PMID:38284123. |
their functions however are not limited to mp inhibition, with each family member harboring numerous mp-independent biological functions that play key roles in processes such as inflammation and apoptosis. |
2024-03-05 |
2024-03-07 |
Not clear |
| Guilin Wang, Jun Mi, Jiangtao Bai, Qiqi He, Xiaoran Li, Zhiping Wan. Non-Coding RNAs in Kidney Stones. Biomolecules. vol 14. issue 2. 2024-02-24. PMID:38397450. |
mirnas have been studied quite extensively in nephrolithiasis, and a plethora of specific mirnas have been implicated in the pathogenesis of nephrolithiasis, involving remarkable changes in calcium metabolism, oxalate metabolism, oxidative stress, cell-crystal adhesion, cellular autophagy, apoptosis, and macrophage (mp) polarization and metabolism. |
2024-02-24 |
2024-02-26 |
Not clear |
| Nhu Thi Quynh Mai, Ulziituya Batjargal, Won-Seok Kim, Ji-Hoon Kim, Ji-Won Park, Ihn-Sil Kwak, Byoung-San Moo. Microplastic induces mitochondrial pathway mediated cellular apoptosis in mussel (Mytilus galloprovincialis) via inhibition of the AKT and ERK signaling pathway. Cell death discovery. vol 9. issue 1. 2023-12-06. PMID:38057300. |
furthermore, analysis of transcriptional activities of key genes for apoptosis of 100 mg/l-day 14 groups revealed the upregulation of both intrinsic and extrinsic apoptotic induction pathway and increment in gene transcripts involving genotoxic stress and energy metabolism according to mp morphotypes. |
2023-12-06 |
2023-12-10 |
Not clear |
| Tian Gan, Jianwei Yu, Jun H. miRNA, lncRNA and circRNA: targeted molecules with therapeutic promises in Mycoplasma pneumoniae infection. Archives of microbiology. vol 205. issue 8. 2023-07-21. PMID:37477725. |
this article reviews the mechanisms by which mirnas, lncrnas, and circrnas mediate mp infection, such as inflammatory responses, apoptosis and pulmonary fibrosis. |
2023-07-21 |
2023-08-14 |
Not clear |
| Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wan. Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans. Chemosphere. 2023-06-14. PMID:37315859. |
in addition, exposure to 10 and 100 μg/l pla mp enhanced germline apoptosis in the gonad. |
2023-06-14 |
2023-08-14 |
caenorhabditis_elegans |
| Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wan. Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans. Chemosphere. 2023-06-14. PMID:37315859. |
accompanied with the enhancement in germline apoptosis, exposure to 10 and 100 μg/l pla mp decreased expression of ced-9 and increased expressions of ced-3, ced-4, and egl-1. |
2023-06-14 |
2023-08-14 |
caenorhabditis_elegans |
| Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wan. Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans. Chemosphere. 2023-06-14. PMID:37315859. |
moreover, the induction of germline apoptosis in pla mp exposed nematodes was suppressed by rnai of ced-3, ced-4, and egl-1, and strengthened by rnai of ced-9. |
2023-06-14 |
2023-08-14 |
caenorhabditis_elegans |