| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shan Gao, Jie Ding, Hai-Jun Xiao, Zhi-Qiang Li, Yan Chen, Xing-Sheng Zhou, Jing-E Wang, Jiang Wu, Wei-Ze Sh. Anti-inflammatory and anti-apoptotic effect of combined treatment with methylprednisolone and amniotic membrane mesenchymal stem cells after spinal cord injury in rats. Neurochemical research. vol 39. issue 8. 2015-10-26. PMID:24890008. |
the combination treatment with mp (50 mg/kg) and delayed transplantation of am-mscs after rat spinal cord injury, significantly reduced (1) myeloperoxidase activity, (2) the proinflammatory cytokines: tumor necrosis factor-α, interleukin (il)-1β, il-6, il-17, interferon-γ and (3) the cell apoptosis [terminal deoxynucleotidyl transferase, dutp nick end labeling (tunel) staining, and caspase-3, bax and bcl-2 expressions]; increased: (1) the levels of the anti-inflammatory cytokines (il-10 and transforming growth factor-β1) and (2) the survival rate of am-mscs in the injury site. |
2015-10-26 |
2023-08-13 |
rat |
| Rui-Rui Zheng, Wei Hu, Cheng-Guang Sui, Nan Ma, You-Hong Jian. Effects of doxorubicin and gemcitabine on the induction of apoptosis in breast cancer cells. Oncology reports. vol 32. issue 6. 2015-06-29. PMID:25269557. |
the results showed that doxorubicin and gemcitabine decreasede proliferation, and increased apoptosis in the mcf7 mp and sp cells in vitro. |
2015-06-29 |
2023-08-13 |
mouse |
| Leonardo A Calderon, Juliana C Sobrinho, Kayena D Zaqueo, Andrea A de Moura, Amy N Grabner, Maurício V Mazzi, Silvana Marcussi, Auro Nomizo, Carla F C Fernandes, Juliana P Zuliani, Bruna M A Carvalho, Saulo L da Silva, Rodrigo G Stábeli, Andreimar M Soare. Antitumoral activity of snake venom proteins: new trends in cancer therapy. BioMed research international. vol 2014. 2015-05-13. PMID:24683541. |
their mechanisms of action include direct toxic action (pla2s), free radical generation (laaos), apoptosis induction (pla2s, mp, and laaos), and antiangiogenesis (disintegrins and lectins). |
2015-05-13 |
2023-08-12 |
mouse |
| Céline Gleizes, Andrei Constantinescu, Malak Abbas, Houda Bouhadja, Fatiha Zobairi, Laurence Kessler, Florence Tot. Liraglutide protects Rin-m5f β cells by reducing procoagulant tissue factor activity and apoptosis prompted by microparticles under conditions mimicking Instant Blood-Mediated Inflammatory Reaction. Transplant international : official journal of the European Society for Organ Transplantation. vol 27. issue 7. 2015-02-02. PMID:24612163. |
cell-derived mps were applied to naive rin-m5f for 24 h. apoptosis, mp release, tf activity, p-iκb expression, and mp-mediated apoptosis were measured in target cells. |
2015-02-02 |
2023-08-12 |
rat |
| Céline Gleizes, Andrei Constantinescu, Malak Abbas, Houda Bouhadja, Fatiha Zobairi, Laurence Kessler, Florence Tot. Liraglutide protects Rin-m5f β cells by reducing procoagulant tissue factor activity and apoptosis prompted by microparticles under conditions mimicking Instant Blood-Mediated Inflammatory Reaction. Transplant international : official journal of the European Society for Organ Transplantation. vol 27. issue 7. 2015-02-02. PMID:24612163. |
indirect cytoprotection led to 20% reduction in mp generation, thereby lowering mp-mediated apoptosis (6.3% vs. 3.7%, p = 0.022) and nf-κb activation (-50%) in target cells. |
2015-02-02 |
2023-08-12 |
rat |
| Kamlesh K Bhopale, Miriam Falzon, G A S Ansari, Bhupendra S Kaphali. Alcohol oxidizing enzymes and ethanol-induced cytotoxicity in rat pancreatic acinar AR42J cells. In vitro cellular & developmental biology. Animal. vol 50. issue 4. 2014-12-12. PMID:24281792. |
confluent ar42j cells were pre-treated with inhibitors of adh class i and ii [4-methylpyrazole (mp)] or class i, ii, and iii [1,10-phenanthroline (pt)], cytochrome p450 2e1 (trans-1,2-dichloroethylene) or catalase (sodium azide) followed by incubation with 800 mg% ethanol at 37°c for 6 h. ethanol metabolism, cell viability, cytotoxicity (apoptosis and necrosis), cell proliferation status, and formation of faees in ar42j cells were measured. |
2014-12-12 |
2023-08-12 |
rat |
| Diane M Spencer, Julie Gauley, David S Pisetsk. The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis. Innate immunity. vol 20. issue 3. 2014-11-25. PMID:23839527. |
taken together, these studies indicate that the nucleic acid content of mps from activated and apoptotic cells have important similarities, suggesting that events during tlr activation may lead to apoptosis and subsequent mp release. |
2014-11-25 |
2023-08-12 |
Not clear |
| C Chen, R L Yan. A phthalide derivative isolated from endophytic fungi Pestalotiopsis photiniae induces G1 cell cycle arrest and apoptosis in human HeLa cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 46. issue 8. 2014-10-03. PMID:23903687. |
flow cytometry showed that mp induced g1 cell cycle arrest and apoptosis in a dose-dependent manner. |
2014-10-03 |
2023-08-12 |
human |
| Armen V Gyulkhandanyan, Asuman Mutlu, David J Allen, John Freedman, Valery Leyti. BH3-mimetic ABT-737 induces strong mitochondrial membrane depolarization in platelets but only weakly stimulates apoptotic morphological changes, platelet shrinkage and microparticle formation. Thrombosis research. vol 133. issue 1. 2014-10-01. PMID:24268298. |
little is known, however, about the relationship between ΔΨm depolarization and downstream morphological manifestations of platelet apoptosis, cell shrinkage and microparticle (mp) formation. |
2014-10-01 |
2023-08-12 |
Not clear |
| Wei Wang, Cheng-Hai Zhao, Ning Zhang, Jian Wan. Vitamin D analog EB1089 induces apoptosis in a subpopulation of SGC-7901 gastric cancer cells through a mitochondrial-dependent apoptotic pathway. Nutrition and cancer. vol 65. issue 7. 2014-06-26. PMID:24099173. |
eb1089 decreased the proliferation, increased apoptosis, and induced mitochondrial damage in the sp cells isolated from 1 cell type (sgc-7901), but not mp cells, through increased bax and decreased bcl-2 and bcl-xl protein expression. |
2014-06-26 |
2023-08-12 |
Not clear |
| Pu Xia, Wen-Feng Gou, Shuang Zhao, Hua-Chuan Zhen. Crizotinib may be used in Lewis lung carcinoma: a novel use for crizotinib. Oncology reports. vol 30. issue 1. 2014-01-17. PMID:23615728. |
our results indicate that crizotinib can induce apoptosis and g1 phase arrest in llc mp cells. |
2014-01-17 |
2023-08-12 |
Not clear |
| Friedrich Felix Hoyer, Meike Kristin Giesen, Carolina Nunes França, Dieter Lütjohann, Georg Nickenig, Nikos Werne. Monocytic microparticles promote atherogenesis by modulating inflammatory cells in mice. Journal of cellular and molecular medicine. vol 16. issue 11. 2014-01-06. PMID:22697268. |
microparticles (mp) are generated during a vast number of biological processes such as inflammation, cell activation and apoptosis. |
2014-01-06 |
2023-08-12 |
mouse |
| Yu hong Jing, Yi ping Hou, Yan feng Song, Jie Yi. Methylprednisolone improves the survival of new neurons following transient cerebral ischemia in rats. Acta neurobiologiae experimentalis. vol 72. issue 3. 2013-11-19. PMID:23093011. |
mp was found to decrease apoptosis and tnf-alpha and il-6 expression at 3 days after mcao in the ipsilateral striatum. |
2013-11-19 |
2023-08-12 |
rat |
| Yu hong Jing, Yi ping Hou, Yan feng Song, Jie Yi. Methylprednisolone improves the survival of new neurons following transient cerebral ischemia in rats. Acta neurobiologiae experimentalis. vol 72. issue 3. 2013-11-19. PMID:23093011. |
these results indicate that early mp administration can improve the neurological deficit and enhance the survival of new neurons in the ipsilateral striatum by inhibiting apoptosis and downregulation of inflammatory response after transient cerebral ischemia in rats. |
2013-11-19 |
2023-08-12 |
rat |
| Yu Hirano, Keiko Kowata, Mikie Kodama, Yasuo Komats. Development of a scanning electrochemical microscopy-based micropipette and its application to analysis of topographic change of single-cell. Bioelectrochemistry (Amsterdam, Netherlands). vol 92. 2013-10-25. PMID:23466409. |
cellular responses induced by mp delivery could be monitored by the secm, and cell apoptosis was successfully detected by adding a kinase inhibitor of two orders of magnitude less than what is required in the conventional method. |
2013-10-25 |
2023-08-12 |
Not clear |
| Kathryn Date, Jessica Hall, John Greenman, Anthony Maraveyas, Leigh A Madde. Tumour and microparticle tissue factor expression and cancer thrombosis. Thrombosis research. vol 131. issue 2. 2013-09-19. PMID:23237339. |
chemotherapy may, in eliciting cancer cell apoptosis, result in an increase in release of circulating procoagulant mp. |
2013-09-19 |
2023-08-12 |
Not clear |
| R Lacroix, C Judicone, P Poncelet, S Robert, L Arnaud, J Sampol, F Dignat-Georg. Impact of pre-analytical parameters on the measurement of circulating microparticles: towards standardization of protocol. Journal of thrombosis and haemostasis : JTH. vol 10. issue 3. 2013-07-08. PMID:22212198. |
microparticles (mp) are small vesicles of 0.1-1 μm, released in response to activation or apoptosis. |
2013-07-08 |
2023-08-12 |
Not clear |
| I V Mindukshev, N I Rukoiatkina, I A Dobrylko, E A Skverchinskaia, E R Nikitina, V V Krivoshlyk, S P Gambarian, A I Krivchenk. [Characterisation of enucleated cells apoptosis: human platelets and erythrocytes]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 99. issue 1. 2013-06-18. PMID:23659060. |
induction of platelet apoptosis by both methods (t/c and abt-373) lead to strong phosphoetydilserine (ps) externalization, loss of the mitochondrial membrane potential (deltapsim), proteolytic cleavage of some cytoskeletal and regulatory proteins, and microparticle (mp) formation. |
2013-06-18 |
2023-08-12 |
human |
| I V Mindukshev, N I Rukoiatkina, I A Dobrylko, E A Skverchinskaia, E R Nikitina, V V Krivoshlyk, S P Gambarian, A I Krivchenk. [Characterisation of enucleated cells apoptosis: human platelets and erythrocytes]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 99. issue 1. 2013-06-18. PMID:23659060. |
erythrocytes apoptosis induced by tbh is characterized by formation ofmethb, cell shrinkage, fast (95 % during 3 hours) ps externalization, yield of hemoglobin, probably by vesicle (mp) formation. |
2013-06-18 |
2023-08-12 |
human |
| David Varon, Yael Hayon, Olga Dashevsky, Ela Sha. Involvement of platelet derived microparticles in tumor metastasis and tissue regeneration. Thrombosis research. vol 130 Suppl 1. 2013-05-20. PMID:23026678. |
microparticles (mp) are small plasma membrane vesicles shed from cells upon their activation or apoptosis. |
2013-05-20 |
2023-08-12 |
Not clear |