| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Schmidt, S Stürzebecher, K V Toyka, R Gol. Interferon-beta treatment of experimental autoimmune encephalomyelitis leads to rapid nonapoptotic termination of T cell infiltration. Journal of neuroscience research. vol 65. issue 1. 2001-08-16. PMID:11433430. |
in moderate eae, the rate of t cell apoptosis was slightly increased after ifn-beta (21.2% +/- 5.2% vs. 17.4% +/- 5.0% in controls), whereas mp alone (25.5% +/- 3.5%, p < 0.01 vs. controls) and the combination therapy (22.4% +/- 4.8%, p < 0.05 vs. controls) had a clear augmenting effect. |
2001-08-16 |
2023-08-12 |
rat |
| H Miyake, I Hara, K Gohji, S Arakawa, S Kamidon. p53 modulation of Fas/Apo-1 mediated apoptosis in a human renal cell carcinoma cell line. International journal of oncology. vol 12. issue 2. 2001-03-01. PMID:9458377. |
the anti-fas monoclonal antibody (ch11) induced apoptosis in the achn/c cells in a dose-dependent manner, whereas the effect of ch11 on the achn/ mp cells was markedly suppressed. |
2001-03-01 |
2023-08-12 |
human |
| N Tong, S W Perry, Q Zhang, H J James, H Guo, A Brooks, H Bal, S A Kinnear, S Fine, L G Epstein, D Dairaghi, T J Schall, H E Gendelman, S Dewhurst, L R Sharer, H A Gelbar. Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. Journal of immunology (Baltimore, Md. : 1950). vol 164. issue 3. 2000-02-24. PMID:10640747. |
hiv-1-infected mononuclear phagocytes (mp) present in inflammatory infiltrates produce neurotoxins that mediate inflammation, dysfunction, and neuronal apoptosis. |
2000-02-24 |
2023-08-12 |
human |
| N Ozbek, E Erdemli, G Hiçsönmez, H Okur, M Tekelioğl. Effects of methylprednisolone on human myeloid leukemic cells in vitro. American journal of hematology. vol 60. issue 4. 1999-04-22. PMID:10203097. |
a marked increase in mp-induced apoptosis of leukemic cells, with a maximum effect at 24 hr of exposure to both low and high concentrations of mp (10(-6) m and 10(-3) m), was demonstrated by light microscopy in cultures of four (three with aml-m1 and one with aml-m7) of the nine patients. |
1999-04-22 |
2023-08-12 |
human |
| N Ozbek, E Erdemli, G Hiçsönmez, H Okur, M Tekelioğl. Effects of methylprednisolone on human myeloid leukemic cells in vitro. American journal of hematology. vol 60. issue 4. 1999-04-22. PMID:10203097. |
the results of the present study, together with our previous clinical experience, suggest that mp, especially at high doses, could have a significant role in the treatment of some aml patients by inducing apoptosis and differentiation of leukemic cells. |
1999-04-22 |
2023-08-12 |
human |
| D Gottardi, A M De Leo, A Alfarano, A Stacchini, P Circosta, M G Gregoretti, L Bergui, M Aragno, F Caligaris-Cappi. Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells: in vitro/in vivo correlations. British journal of haematology. vol 99. issue 1. 1997-12-09. PMID:9359515. |
the amount of apoptosis was significantly higher in the samples treated with f-ara-a than in those exposed to mp alone. |
1997-12-09 |
2023-08-12 |
Not clear |
| D Gottardi, A M De Leo, A Alfarano, A Stacchini, P Circosta, M G Gregoretti, L Bergui, M Aragno, F Caligaris-Cappi. Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells: in vitro/in vivo correlations. British journal of haematology. vol 99. issue 1. 1997-12-09. PMID:9359515. |
in the seven remaining cases, no bcl-2 down-regulation was observed after exposure to f-ara-a and the degree of f-ara-a-induced apoptosis overlapped that induced by mp. |
1997-12-09 |
2023-08-12 |
Not clear |
| A J Morris, M F Taylor, I D Morri. Leydig cell apoptosis in response to ethane dimethanesulphonate after both in vivo and in vitro treatment. Journal of andrology. vol 18. issue 3. 1997-08-21. PMID:9203055. |
experiments were conducted to determine whether the leydig cell will undergo apoptosis in response to eds or methylprednisolone (mp), a glucocorticoid known to cause apoptosis in a number of other cell types. |
1997-08-21 |
2023-08-12 |
rat |
| A J Morris, M F Taylor, I D Morri. Leydig cell apoptosis in response to ethane dimethanesulphonate after both in vivo and in vitro treatment. Journal of andrology. vol 18. issue 3. 1997-08-21. PMID:9203055. |
increasing the concentration of eds or mp resulted in a dose-dependent increase in the incidence of apoptosis that reached a maximum of 25% (eds) or 12% (mp) of detached cells. |
1997-08-21 |
2023-08-12 |
rat |
| G Morris, S J DeNardo, G L DeNardo, T Leshchinsky, B Wu, P C Mack, M D Winthrop, P H Gumerloc. Decreased C-MYC and BCL2 expression correlates with methylprednisolone-mediated inhibition of Raji lymphoma growth. Biochemical and molecular medicine. vol 60. issue 2. 1997-07-07. PMID:9169090. |
the goal was to determine the modulation of expression of the oncogenes (c-myc and bcl2), the p53 pathway described above, and the apoptosis marker tgf-beta 1 in the human raji lymphoma following mp treatment. |
1997-07-07 |
2023-08-12 |
mouse |
| M Massaia, P Borrione, C Attisano, P Barral, E Beggiato, L Montacchini, A Bianchi, M Boccadoro, A Piler. Dysregulated Fas and Bcl-2 expression leading to enhanced apoptosis in T cells of multiple myeloma patients. Blood. vol 85. issue 12. 1995-07-20. PMID:7540069. |
the percentage of apoptotic cells after incubation in medium alone (spontaneous apoptosis) or in the presence of methylprednisolone (mp) or anti-fas monoclonal antibody (triggered apoptosis) was significantly higher in mm and mainly restricted to hla-dr+ t cells. |
1995-07-20 |
2023-08-12 |
Not clear |