| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenqi Fu, Yeong-Gwan Im, Byunggook Kim, Ok-Su Kim, Ying Yang, Jianan Song, Danyang Liu, Siyu Zhu, Jae-Seok Kang, Okjoon Ki. 625 nm Light Irradiation Prevented MC3T3-E1 Cells from Accumulation of Misfolded Proteins via ROS and ATP Production. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298212. |
mp accumulation contributes to cellular apoptosis and bone disorders. |
2023-06-11 |
2023-08-14 |
Not clear |
| Michele Aramburu Serafini, Dienifer Hermann Sirena, Ana Beatriz Tittoni da Silveira, Monique Franco-da-Silva, Mariana Rauback Aubin, Tuane Nerissa Alves Garcez, Anelise Araújo, Fernanda Dos Santos Pereira, Martin J Hoogduijn, Fabiany da Costa Gonçalves, Ana Helena Pa. Mesenchymal stromal cell-derived membrane particles: A novel cell-free therapy for inflammatory bowel diseases. International immunopharmacology. vol 118. 2023-04-08. PMID:37030123. |
our findings revealed that mp, cm, and living msc ameliorated dss-induced colitis by reducing colonic inflammation, the loss of colonic goblet cells, and intestinal mucosa permeability, preventing apoptosis of damaged colonic cells and balancing th1 and th2 activity. |
2023-04-08 |
2023-08-14 |
mouse |
| Chaofan Sun, Jia Teng, Dongyu Wang, Jianmin Zhao, Encui Shan, Qing Wan. The adverse impact of microplastics and their attached pathogen on hemocyte function and antioxidative response in the mussel Mytilus galloprovincialis. Chemosphere. 2023-03-12. PMID:36907490. |
coexposure can induce hemocytes to produce higher ros, improve phagocytosis, significantly reduce the stability of the lysosome membrane, and induce the expression of apoptosis-related genes, causing apoptosis of hemocytes compared with single mp exposure. |
2023-03-12 |
2023-08-14 |
human |
| Tianyi Chen, Haoze Chen, Anli Wang, Weixuan Yao, Zhongshi Xu, Binjie Wang, Jiye Wang, Yuanzhao W. Methyl Parathion Exposure Induces Development Toxicity and Cardiotoxicity in Zebrafish Embryos. Toxics. vol 11. issue 1. 2023-01-20. PMID:36668810. |
exposure to mp resulted in the accumulation of reactive oxygen species (ros), decreased superoxide dismutase (sod) activity, increased catalase (cat) activity, elevated malondialdehyde (mda) levels, and caused cardiac apoptosis in zebrafish embryos. |
2023-01-20 |
2023-08-14 |
cat |
| Yaling Yu, Lishan Lin, Kangping Liu, Yixin Jiang, Zhenlei Zho. Effects of Simvastatin on Cartilage Homeostasis in Steroid-Induced Osteonecrosis of Femoral Head by Inhibiting Glucocorticoid Receptor. Cells. vol 11. issue 24. 2022-12-23. PMID:36552711. |
furthermore, mp treatment induced apoptosis and high-level catabolism and low-level anabolism in vitro and vivo, while simvastatin significantly decreased catabolism and slightly recovered anabolism via inhibiting gr and the hypoxia-inducible factor (hif) pathway. |
2022-12-23 |
2023-08-14 |
Not clear |
| Andry Ny Aina Rabezanahary, Mathilde Piette, Omayma Missawi, Mutien- Marie Garigliany, Patrick Kestemont, Cornet Valéri. Microplastics alter development, behavior, and innate immunity responses following bacterial infection during zebrafish embryo-larval development. Chemosphere. 2022-10-28. PMID:36306963. |
our results indicated a difference in immune system (nfkb, il1β) and apoptosis (casp3a, bcl2) related gene expression depending on the timing of mp exposure, which highlighted a contrasting sensitivity according to the exposure time in mp studies. |
2022-10-28 |
2023-08-14 |
zebrafish |
| Wei Fang, Jingyu Huang, Jun Wang, Tengyi Huang, Dajia Lin, Jun Yi. Blockade of interleukin-6 receptor attenuates apoptosis and modulates the inflammatory response in Mycoplasma pneumoniae infected A549 cells. American journal of translational research. vol 14. issue 9. 2022-10-17. PMID:36247299. |
to investigate the effect of silencing the interleukin (il)-6 gene on the induction of inflammation, oxidative stress and apoptosis in mycoplasma pneumoniae (mp) infected a549 cells and its mechanism of action. |
2022-10-17 |
2023-08-14 |
Not clear |
| Li-Tzu Huang, Chin-Ho Kuo, Lin Tseng, Yi-Syuan Li, Li-Hsin Cheng, Chin-Yun Cheng, Shane-Rong Sheu, Wen-Tsan Chang, Chien-Chin Chen, Hung-Chi Chen. Alpha-Mangostin Reduces Pericellular Fibronectin on Suspended Tumor Cells and Therapeutically, but Not Prophylactically, Suppresses Distant Metastasis. Life (Basel, Switzerland). vol 12. issue 9. 2022-09-23. PMID:36143411. |
immunofluorescence staining, mtt assays, flow cytometric assays, immunoblotting, and experimental metastasis mouse models were used to detect the effects of mp extracts or α-mg on perifn on stcs, tumor cell proliferation and apoptosis, the akt activity, and tumor lung metastasis. |
2022-09-23 |
2023-08-14 |
mouse |
| Jin-Lei Sun, Tai-Biao Lyu, Zhi-Lei Chen, Chao-Feng Lian, Su-Ying Liu, Ti-Hong Shao, Shuo Zhang, Li-Ling Zhao, Jin-Jing Liu, Lin-Yi Peng, Li Zhang, Yun-Jiao Yang, Feng-Chun Zhang, Hua Che. Methylprednisolone pulse therapy promotes the differentiation of regulatory T cells by inducing the apoptosis of CD4 Clinical immunology (Orlando, Fla.). 2022-07-16. PMID:35842211. |
methylprednisolone pulse therapy promotes the differentiation of regulatory t cells by inducing the apoptosis of cd4 to investigate the differentiation of regulatory t cells (tregs) induced by methylprednisolone (mp) pulse therapy in patients with systemic lupus erythematosus (sle). |
2022-07-16 |
2023-08-14 |
Not clear |
| Zhikun Zhang, Ruijie Wan, Qing Yuan, Haiwei Dou, Peng Tu, Dawei Shi, Xiaoyan Fu, Deli Xi. Cell damage and neutrophils promote the infection of Mycoplasma pneumoniae and inflammatory response. Microbial pathogenesis. 2022-06-20. PMID:35724831. |
further, we found live neutrophils show bactericidal activity to mp, and the phagocytosis of mp promotes apoptosis of neutrophils. |
2022-06-20 |
2023-08-14 |
human |
| Ramesh Kumar Paidi, Sukanya Sarkar, Naqiya Ambareen, Subhas Chandra Biswa. Medha Plus - A novel polyherbal formulation ameliorates cognitive behaviors and disease pathology in models of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 151. 2022-05-26. PMID:35617801. |
viability assays revealed that mp prevented aβ-induced loss of neurites as well as neuronal apoptosis in cellular models. |
2022-05-26 |
2023-08-13 |
mouse |
| Chan Yu, Linghui Zhan. Methylprednisolone up-regulates annexin A1 (ANXA1) to inhibit the inflammation, apoptosis and oxidative stress of cigarette smoke extract (CSE)-induced bronchial epithelial cells, a chronic obstructive pulmonary disease in vitro model, through the formyl peptide receptor 2 (FPR2) receptors and the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) pathway. Bioengineered. vol 13. issue 2. 2022-02-07. PMID:35129068. |
mp enhanced the viability but suppressed the apoptosis, inflammatory response and oxidative stress of cse-induced beas-2b cells via regulating fpr2/ampk pathway, while anxa1 knockdown exhibited oppositive effects on them. |
2022-02-07 |
2023-08-13 |
human |
| Chan Yu, Linghui Zhan. Methylprednisolone up-regulates annexin A1 (ANXA1) to inhibit the inflammation, apoptosis and oxidative stress of cigarette smoke extract (CSE)-induced bronchial epithelial cells, a chronic obstructive pulmonary disease in vitro model, through the formyl peptide receptor 2 (FPR2) receptors and the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) pathway. Bioengineered. vol 13. issue 2. 2022-02-07. PMID:35129068. |
in conclusion, mp up-regulated anxa1 to inhibit the inflammation, apoptosis and oxidative stress of beas-2b cells induced by cse, alleviating copd through suppressing the fpr2/ampk pathway. |
2022-02-07 |
2023-08-13 |
human |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
vesicular stomatitis virus (vsv) matrix protein (mp) induces the apoptosis of tumor cells in the absence of other viral components. |
2021-10-21 |
2023-08-12 |
mouse |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
in our previous studies, we successfully constructed the pvax-m plasmid from the pvax plasmid, which expressed wild-type vsv mp (vsv mp is under the control of the cmv promoter) and demonstrated that pvax-m efficiently suppresses the growth of malignant tumors via the induction of apoptosis in vitro and in vivo. |
2021-10-21 |
2023-08-12 |
mouse |
| Zongshu Li, Juan DU, Hongxia Sun, Jing Mang, Jinting He, Jiaoqi Wang, Hongyu Liu, Zhongxin X. Effects of the combination of methylprednisolone with aminoguanidine on functional recovery in rats following spinal cord injury. Experimental and therapeutic medicine. vol 7. issue 6. 2021-10-21. PMID:24926352. |
in rats with sci, the combination therapy group treated with ag (75 mg/kg) and mp (0.75 mg/kg) exhibited significantly reduced levels of cytokine expression and cell apoptosis compared with those in the control group. |
2021-10-21 |
2023-08-13 |
rat |
| Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Hongguang Wu, Haruki Yamada, Toshihiko Hiran. Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition. Steroids. vol 163. 2021-07-19. PMID:32818521. |
this effect seemed to be related to the potentiation of tet action by mp to induce apoptosis. |
2021-07-19 |
2023-08-13 |
human |
| Fleury Augustin Nsole Biteghe, Eden Padayachee, Lester M Davids, Nyangone Ekome Toung Chalomie, Jean De La Croix Ndong, Stefan Bart. Desensitization of metastatic melanoma cells to therapeutic treatment through repeated exposure to dacarbazine. Journal of photochemistry and photobiology. B, Biology. vol 211. 2021-04-30. PMID:32866820. |
likewise, hyp-pdt and combination therapy significantly reduced self-renewal capacity, increased expression of abcb5 and abcg2 transporters and differentially induced cell cycle arrest and cell death (apoptosis or necrosis) depending on the melanoma mp cell type. |
2021-04-30 |
2023-08-13 |
Not clear |
| Katia Mellal, Samy Omri, Mukandila Mulumba, Houda Tahiri, Carl Fortin, Marie-France Dorion, Hung Pham, Yesica Garcia Ramos, Jinqiang Zhang, Sheetal Pundir, Jean-Sébastien Joyal, Jean-François Bouchard, Florian Sennlaub, Maria Febbraio, Pierre Hardy, Simon-Pierre Gravel, Sylvie Marleau, William D Lubell, Sylvain Chemtob, Huy On. Immunometabolic modulation of retinal inflammation by CD36 ligand. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31501473. |
accordingly, ppar-γ inhibition blocked the cytoprotective effect of mpe-001 on photoreceptor apoptosis elicited by activated mp. |
2020-10-27 |
2023-08-13 |
mouse |
| Victor Udo Nna, Ainul Bahiyah Abu Bakar, Azlina Ahmad, Chinedum Ogbonnaya Eleazu, Mahaneem Mohame. Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin-Induced Diabetic Rats: Combined Protective Effects of Malaysian Propolis and Metformin. Antioxidants (Basel, Switzerland). vol 8. issue 10. 2020-09-28. PMID:31600920. |
herein, we investigated the effect of malaysian propolis (mp) on testicular oxidative stress, inflammation and apoptosis in diabetic rats. |
2020-09-28 |
2023-08-13 |
rat |