| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Fang, Jingyu Huang, Jun Wang, Tengyi Huang, Dajia Lin, Jun Yi. Blockade of interleukin-6 receptor attenuates apoptosis and modulates the inflammatory response in Mycoplasma pneumoniae infected A549 cells. American journal of translational research. vol 14. issue 9. 2022-10-17. PMID:36247299. |
to investigate the effect of silencing the interleukin (il)-6 gene on the induction of inflammation, oxidative stress and apoptosis in mycoplasma pneumoniae (mp) infected a549 cells and its mechanism of action. |
2022-10-17 |
2023-08-14 |
Not clear |
| Li-Tzu Huang, Chin-Ho Kuo, Lin Tseng, Yi-Syuan Li, Li-Hsin Cheng, Chin-Yun Cheng, Shane-Rong Sheu, Wen-Tsan Chang, Chien-Chin Chen, Hung-Chi Chen. Alpha-Mangostin Reduces Pericellular Fibronectin on Suspended Tumor Cells and Therapeutically, but Not Prophylactically, Suppresses Distant Metastasis. Life (Basel, Switzerland). vol 12. issue 9. 2022-09-23. PMID:36143411. |
immunofluorescence staining, mtt assays, flow cytometric assays, immunoblotting, and experimental metastasis mouse models were used to detect the effects of mp extracts or α-mg on perifn on stcs, tumor cell proliferation and apoptosis, the akt activity, and tumor lung metastasis. |
2022-09-23 |
2023-08-14 |
mouse |
| Jin-Lei Sun, Tai-Biao Lyu, Zhi-Lei Chen, Chao-Feng Lian, Su-Ying Liu, Ti-Hong Shao, Shuo Zhang, Li-Ling Zhao, Jin-Jing Liu, Lin-Yi Peng, Li Zhang, Yun-Jiao Yang, Feng-Chun Zhang, Hua Che. Methylprednisolone pulse therapy promotes the differentiation of regulatory T cells by inducing the apoptosis of CD4 Clinical immunology (Orlando, Fla.). 2022-07-16. PMID:35842211. |
methylprednisolone pulse therapy promotes the differentiation of regulatory t cells by inducing the apoptosis of cd4 to investigate the differentiation of regulatory t cells (tregs) induced by methylprednisolone (mp) pulse therapy in patients with systemic lupus erythematosus (sle). |
2022-07-16 |
2023-08-14 |
Not clear |
| Zhikun Zhang, Ruijie Wan, Qing Yuan, Haiwei Dou, Peng Tu, Dawei Shi, Xiaoyan Fu, Deli Xi. Cell damage and neutrophils promote the infection of Mycoplasma pneumoniae and inflammatory response. Microbial pathogenesis. 2022-06-20. PMID:35724831. |
further, we found live neutrophils show bactericidal activity to mp, and the phagocytosis of mp promotes apoptosis of neutrophils. |
2022-06-20 |
2023-08-14 |
human |
| Ramesh Kumar Paidi, Sukanya Sarkar, Naqiya Ambareen, Subhas Chandra Biswa. Medha Plus - A novel polyherbal formulation ameliorates cognitive behaviors and disease pathology in models of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 151. 2022-05-26. PMID:35617801. |
viability assays revealed that mp prevented aβ-induced loss of neurites as well as neuronal apoptosis in cellular models. |
2022-05-26 |
2023-08-13 |
mouse |
| Chan Yu, Linghui Zhan. Methylprednisolone up-regulates annexin A1 (ANXA1) to inhibit the inflammation, apoptosis and oxidative stress of cigarette smoke extract (CSE)-induced bronchial epithelial cells, a chronic obstructive pulmonary disease in vitro model, through the formyl peptide receptor 2 (FPR2) receptors and the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) pathway. Bioengineered. vol 13. issue 2. 2022-02-07. PMID:35129068. |
mp enhanced the viability but suppressed the apoptosis, inflammatory response and oxidative stress of cse-induced beas-2b cells via regulating fpr2/ampk pathway, while anxa1 knockdown exhibited oppositive effects on them. |
2022-02-07 |
2023-08-13 |
human |
| Chan Yu, Linghui Zhan. Methylprednisolone up-regulates annexin A1 (ANXA1) to inhibit the inflammation, apoptosis and oxidative stress of cigarette smoke extract (CSE)-induced bronchial epithelial cells, a chronic obstructive pulmonary disease in vitro model, through the formyl peptide receptor 2 (FPR2) receptors and the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) pathway. Bioengineered. vol 13. issue 2. 2022-02-07. PMID:35129068. |
in conclusion, mp up-regulated anxa1 to inhibit the inflammation, apoptosis and oxidative stress of beas-2b cells induced by cse, alleviating copd through suppressing the fpr2/ampk pathway. |
2022-02-07 |
2023-08-13 |
human |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
vesicular stomatitis virus (vsv) matrix protein (mp) induces the apoptosis of tumor cells in the absence of other viral components. |
2021-10-21 |
2023-08-12 |
mouse |
| Ping Zhang, Jiao Tan, DA-Bing Yang, Zi-Chao Luo, Shan Luo, Ping Chen, Ping Sun, Yi Zhou, Xian-Cheng Chen, Yu-Quan Wei, Yan-Jun We. Gene therapy using the human telomerase catalytic subunit gene promoter enables targeting of the therapeutic effects of vesicular stomatitis virus matrix protein against human lung adenocarcinoma. Experimental and therapeutic medicine. vol 4. issue 5. 2021-10-21. PMID:23226739. |
in our previous studies, we successfully constructed the pvax-m plasmid from the pvax plasmid, which expressed wild-type vsv mp (vsv mp is under the control of the cmv promoter) and demonstrated that pvax-m efficiently suppresses the growth of malignant tumors via the induction of apoptosis in vitro and in vivo. |
2021-10-21 |
2023-08-12 |
mouse |
| Zongshu Li, Juan DU, Hongxia Sun, Jing Mang, Jinting He, Jiaoqi Wang, Hongyu Liu, Zhongxin X. Effects of the combination of methylprednisolone with aminoguanidine on functional recovery in rats following spinal cord injury. Experimental and therapeutic medicine. vol 7. issue 6. 2021-10-21. PMID:24926352. |
in rats with sci, the combination therapy group treated with ag (75 mg/kg) and mp (0.75 mg/kg) exhibited significantly reduced levels of cytokine expression and cell apoptosis compared with those in the control group. |
2021-10-21 |
2023-08-13 |
rat |
| Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Hongguang Wu, Haruki Yamada, Toshihiko Hiran. Methylprednisolone potentiates tetrandrine pharmacodynamics against human T lymphoblastoid leukemia MOLT-4 cells via regulation of NF-κB activation and cell cycle transition. Steroids. vol 163. 2021-07-19. PMID:32818521. |
this effect seemed to be related to the potentiation of tet action by mp to induce apoptosis. |
2021-07-19 |
2023-08-13 |
human |
| Fleury Augustin Nsole Biteghe, Eden Padayachee, Lester M Davids, Nyangone Ekome Toung Chalomie, Jean De La Croix Ndong, Stefan Bart. Desensitization of metastatic melanoma cells to therapeutic treatment through repeated exposure to dacarbazine. Journal of photochemistry and photobiology. B, Biology. vol 211. 2021-04-30. PMID:32866820. |
likewise, hyp-pdt and combination therapy significantly reduced self-renewal capacity, increased expression of abcb5 and abcg2 transporters and differentially induced cell cycle arrest and cell death (apoptosis or necrosis) depending on the melanoma mp cell type. |
2021-04-30 |
2023-08-13 |
Not clear |
| Katia Mellal, Samy Omri, Mukandila Mulumba, Houda Tahiri, Carl Fortin, Marie-France Dorion, Hung Pham, Yesica Garcia Ramos, Jinqiang Zhang, Sheetal Pundir, Jean-Sébastien Joyal, Jean-François Bouchard, Florian Sennlaub, Maria Febbraio, Pierre Hardy, Simon-Pierre Gravel, Sylvie Marleau, William D Lubell, Sylvain Chemtob, Huy On. Immunometabolic modulation of retinal inflammation by CD36 ligand. Scientific reports. vol 9. issue 1. 2020-10-27. PMID:31501473. |
accordingly, ppar-γ inhibition blocked the cytoprotective effect of mpe-001 on photoreceptor apoptosis elicited by activated mp. |
2020-10-27 |
2023-08-13 |
mouse |
| Victor Udo Nna, Ainul Bahiyah Abu Bakar, Azlina Ahmad, Chinedum Ogbonnaya Eleazu, Mahaneem Mohame. Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin-Induced Diabetic Rats: Combined Protective Effects of Malaysian Propolis and Metformin. Antioxidants (Basel, Switzerland). vol 8. issue 10. 2020-09-28. PMID:31600920. |
herein, we investigated the effect of malaysian propolis (mp) on testicular oxidative stress, inflammation and apoptosis in diabetic rats. |
2020-09-28 |
2023-08-13 |
rat |
| Hany H Arab, Samir A Salama, Ahmed H Eid, Ahmed M Kabel, Nancy N Shahi. Targeting MAPKs, NF-κB, and PI3K/AKT pathways by methyl palmitate ameliorates ethanol-induced gastric mucosal injury in rats. Journal of cellular physiology. vol 234. issue 12. 2020-06-22. PMID:31115047. |
in the context of apoptosis, mp inhibited the cleavage of caspase-3 and poly(adp-ribose)polymerase (parp) and bax protein expression with upregulating b cell lymphoma-2 expression (bcl-2), thus, promoting gastric cellular survival. |
2020-06-22 |
2023-08-13 |
rat |
| Muhammad Yasir Ali, Imran Tariq, Muhammad Farhan Sohail, Muhammad Umair Amin, Sajid Ali, Shashank Reddy Pinnapireddy, Asad Ali, Jens Schäfer, Udo Bakowsk. Selective anti-ErbB3 aptamer modified sorafenib microparticles: In vitro and in vivo toxicity assessment. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. vol 145. 2019-11-26. PMID:31626948. |
in vitro apoptosis assay, cell viability assay and metastatic progression showed a significant decrease (p < 0.001) in vitro cell viability for mps and mps-apt as compared to mp. |
2019-11-26 |
2023-08-13 |
mouse |
| Lei Duan, Xiao-Lu Wu, Fei Zhao, Rong Zeng, Ke-Hu Yan. Induction Effect to Apoptosis by Maitake Polysaccharide: Synergistic Effect of Its Combination With Vitamin C in Neuroglioma Cell. Journal of evidence-based complementary & alternative medicine. vol 22. issue 4. 2019-08-16. PMID:28528571. |
a combination of mp (1.0 mg/ml) and vc (0.4 mmol/l) led to a 53.10% reduction in cell viability and this treatment induced cell cycle arrest at the g2/m phase, and apoptosis occurred in 38.54% of the cells. |
2019-08-16 |
2023-08-13 |
human |
| Lei Duan, Xiao-Lu Wu, Fei Zhao, Rong Zeng, Ke-Hu Yan. Induction Effect to Apoptosis by Maitake Polysaccharide: Synergistic Effect of Its Combination With Vitamin C in Neuroglioma Cell. Journal of evidence-based complementary & alternative medicine. vol 22. issue 4. 2019-08-16. PMID:28528571. |
the inhibiting effect of combined treatment with mp and vc on m059 k cells indicates the mechanism of anticancer activity involved induction of cell apoptosis. |
2019-08-16 |
2023-08-13 |
human |
| Xingxing Bie, Shuguang Zhang, Xue Luo, Rui-Qun Q. Candida albicans cell wall mannoprotein synergizes with lipopolysaccharide to affect RAW264.7 proliferation, phagocytosis and apoptosis. Microbial pathogenesis. vol 131. 2019-07-29. PMID:30953745. |
mp significantly promoted the proliferation of raw264.7 cells, inhibited their phagocytic capacity, but exerted no significant effects on apoptosis of macrophages. |
2019-07-29 |
2023-08-13 |
Not clear |
| Srabani Mitra, Matthew Exline, Fabien Habyarimana, Mikhail A Gavrilin, Paul J Baker, Seth L Masters, Mark D Wewers, Anasuya Sarka. Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury. American journal of respiratory cell and molecular biology. vol 59. issue 1. 2019-04-15. PMID:29365280. |
furthermore, only mp released from stimulated monocytic cells that contain both cleaved gsdmd and active caspase 1 induce endothelial cell apoptosis. |
2019-04-15 |
2023-08-13 |
Not clear |