| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nadezhda Andreeva, Amarjargal Nyamaa, Heidemarie Haupt, Johann Gross, Birgit Mazure. Recombinant human erythropoietin prevents ischemia-induced apoptosis and necrosis in explant cultures of the rat organ of Corti. Neuroscience letters. vol 396. issue 2. 2006-04-25. PMID:16332412. |
twenty-four hours after the onset of ischemia, the cultures were stained using tetramethyl rhodamine isothiocyanate (tritc) phalloidin (hair cells), propidium iodide (membrane integrity) and apoptosis detection kit (dna-fragmentation). |
2006-04-25 |
2023-08-12 |
human |
| A S Chagin, D Chrysis, M Takigawa, E M Ritzen, L Sävendah. Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocyte proliferation and decreased apoptosis. The Journal of endocrinology. vol 188. issue 2. 2006-04-04. PMID:16461546. |
the human chondrocyte-like cell line hcs-2/8 was used to study estrogen effects on cell proliferation (3h-labeled thymidine uptake) and apoptosis (cell death detection elisa kit). |
2006-04-04 |
2023-08-12 |
human |
| Marcus M Schittenhelm, Sharon Shiraga, Arin Schroeder, Amie S Corbin, Diana Griffith, Francis Y Lee, Carsten Bokemeyer, Michael W N Deininger, Brian J Druker, Michael C Heinric. Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies. Cancer research. vol 66. issue 1. 2006-02-23. PMID:16397263. |
furthermore, dasatinib is a potent inhibitor of imatinib-resistant kit activation loop mutants and induces apoptosis in mast cell and leukemic cell lines expressing these mutations (potency against kit d816y >> d816f > d816v). |
2006-02-23 |
2023-08-12 |
human |
| Hermine Dika Nguea, Bertrand Rihn, Delphine Mahon, Jean-Luc Bernard, Aymon De Reydellet, Alain Le Fao. Effects of various man-made mineral fibers on cell apoptosis and viability. Archives of toxicology. vol 79. issue 9. 2006-01-31. PMID:15856181. |
the physical interaction between u-937 cells and mmmf was observed using scanning electron microscopy, and the cytotoxicity was evaluated by studying cell viability using mtt assay and cell apoptosis with an elisa detection kit. |
2006-01-31 |
2023-08-12 |
Not clear |
| C Liu, I Chu, S Hwan. Pentanoic acid, a novel protein synthesis stimulant for Chinese Hamster Ovary (CHO) cells. Journal of bioscience and bioengineering. vol 91. issue 1. 2005-11-01. PMID:16232949. |
apoptosis (programmed cell death) was observed in the serum-free batch culture of cho cells using a cell death detection elisa kit. |
2005-11-01 |
2023-08-12 |
Not clear |
| Yiqun G Shellman, Deborah Ribble, Leslie Miller, John Gendall, Kayleen Vanbuskirk, Desiree Kelly, David A Norris, Robert P Dellavall. Lovastatin-induced apoptosis in human melanoma cell lines. Melanoma research. vol 15. issue 2. 2005-09-19. PMID:15846140. |
apoptosis was assayed by ethidium bromide and acridine orange morphologic assays, an annexin v apoptosis detection kit and active caspase 3 assays. |
2005-09-19 |
2023-08-12 |
human |
| Yiqun G Shellman, Deborah Ribble, Leslie Miller, John Gendall, Kayleen Vanbuskirk, Desiree Kelly, David A Norris, Robert P Dellavall. Lovastatin-induced apoptosis in human melanoma cell lines. Melanoma research. vol 15. issue 2. 2005-09-19. PMID:15846140. |
for human melanoma cells, lovastatin precipitated cell rounding, increased the percentage of apoptotic cells detected by ethidium bromide and acridine orange staining and by the annexin v apoptosis detection kit, and resulted in a 50-fold increase in active caspase 3, corroborating that lovastatin induced apoptosis. |
2005-09-19 |
2023-08-12 |
human |
| Kazuhiro Noma, Yoshio Naomoto, Mehmet Gunduz, Junji Matsuoka, Tomoki Yamatsuji, Yasuhiro Shirakawa, Tetsuji Nobuhisa, Takaomi Okawa, Munenori Takaoka, Yasuko Tomono, Ohmori Hiroyuki, Esra Gunduz, Noriaki Tanak. Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines. Oncology reports. vol 14. issue 3. 2005-09-15. PMID:16077968. |
to investigate the effects of imatinib on various c-kit mutations found in gists, cell proliferation and apoptosis assays were performed in two gist cell lines with different kit mutations. |
2005-09-15 |
2023-08-12 |
Not clear |
| Wu-Hsien Kuo, Jing-Hsien Chen, Hui-Hsuan Lin, Bi-Chiou Chen, Jeng-Dong Hsu, Chau-Jong Wan. Induction of apoptosis in the lung tissue from rats exposed to cigarette smoke involves p38/JNK MAPK pathway. Chemico-biological interactions. vol 155. issue 1-2. 2005-08-23. PMID:15970277. |
using an in situ cell death detection kit (ta300), the association of cs with apoptosis was determined in a concentration-dependent manner. |
2005-08-23 |
2023-08-12 |
human |
| Hind Assaf, Hayat Azouri, Marc Pallard. Ochratoxin A induces apoptosis in human lymphocytes through down regulation of Bcl-xL. Toxicological sciences : an official journal of the Society of Toxicology. vol 79. issue 2. 2005-05-05. PMID:15056805. |
in particular, human peripheral blood lymphocytes and the human lymphoid t cell line, kit 225 cells, underwent apoptosis in a time- and dose-dependent manner. |
2005-05-05 |
2023-08-12 |
human |
| C Langner, M Lemmerer, P Kornpra. Analysis of KIT (CD117) expression in gallbladder carcinomas by tissue microarray. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. vol 30. issue 8. 2005-03-10. PMID:15336730. |
kit (cd117) is a transmembrane tyrosinase-kinase receptor which has been related to cell proliferation, differentiation, adhesion and control of apoptosis. |
2005-03-10 |
2023-08-12 |
Not clear |
| Satoko Kimura, Tamihiro Kawakami, Yoko Kawa, Yoshinao Soma, Tsuneto Kushimoto, Masayuki Nakamura, Hidenori Watabe, Shiho Ooka, Masako Mizoguch. Bcl-2 reduced and fas activated by the inhibition of stem cell factor/KIT signaling in murine melanocyte precursors. The Journal of investigative dermatology. vol 124. issue 1. 2005-03-07. PMID:15654978. |
using the nccmelb4 cell line, we investigated the occurrence of apoptosis in the cultured cells when kit receptors were blocked by the monoclonal anti-kit antibody (ack2). |
2005-03-07 |
2023-08-12 |
mouse |
| Marianna Kulka, Dean D Metcalf. High-resolution tracking of cell division demonstrates differential effects of TH1 and TH2 cytokines on SCF-dependent human mast cell production in vitro: correlation with apoptosis and Kit expression. Blood. vol 105. issue 2. 2005-02-15. PMID:15367434. |
high-resolution tracking of cell division demonstrates differential effects of th1 and th2 cytokines on scf-dependent human mast cell production in vitro: correlation with apoptosis and kit expression. |
2005-02-15 |
2023-08-12 |
human |
| Marianna Kulka, Dean D Metcalf. High-resolution tracking of cell division demonstrates differential effects of TH1 and TH2 cytokines on SCF-dependent human mast cell production in vitro: correlation with apoptosis and Kit expression. Blood. vol 105. issue 2. 2005-02-15. PMID:15367434. |
to determine the effect of these cytokines on stem cell factor (scf)-dependent human mast cell production, we used high-resolution tracking of cell division and correlated the results with cell apoptosis, expression of kit, and mast cell degranulation. |
2005-02-15 |
2023-08-12 |
human |
| Jia Fei, Huan Zhan. [Effect and mechanism of VEGF antisense phosphorothioate deoxynucleotides on HL-60 leukemic cells]. Zhongguo shi yan xue ye xue za zhi. vol 12. issue 5. 2005-01-26. PMID:15498126. |
after culture for 72 hours, inhibitive rate of cell growth was detected with mtt methods, viable cells were counted with trypan blue exclusion each 24 hour, cell configuration and apoptosis were observed with geimsa staining and flow cytometry respectively, level of vegf protein was detected with vegf elisa kit. |
2005-01-26 |
2023-08-12 |
Not clear |
| S Wong, J McLaughlin, D Cheng, C Zhang, K M Shokat, O N Witt. Sole BCR-ABL inhibition is insufficient to eliminate all myeloproliferative disorder cell populations. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 50. 2005-01-14. PMID:15505216. |
in the cellular context of mature myeloid cells and pro/pre b cells that do not express kit, monospecific bcr-abl inhibition was quantitatively as effective as imatinib mesylate in suppressing cell growth and inducing apoptosis. |
2005-01-14 |
2023-08-12 |
Not clear |
| Zs Pirger, K Elekes, T Kis. Functional morphology of the salivary gland of the snail, Helix pomatia: a histochemical and immunocytochemical study. Acta biologica Hungarica. vol 55. issue 1-4. 2005-01-13. PMID:15270238. |
using an apoptosis kit, we could also establish that this process was due to rather an apoptotic than a necrotic mechanism. |
2005-01-13 |
2023-08-12 |
mouse |
| G Sakuntala Warshamana-Greene, Julie Litz, Elisabeth Buchdunger, Francesco Hofmann, Carlos García-Echeverría, Geoffrey W Krysta. The insulin-like growth factor-I (IGF-I) receptor kinase inhibitor NVP-ADW742, in combination with STI571, delineates a spectrum of dependence of small cell lung cancer on IGF-I and stem cell factor signaling. Molecular cancer therapeutics. vol 3. issue 5. 2005-01-11. PMID:15141010. |
previous data suggested that igf-i protects cells from apoptosis induced by sti571, an efficient inhibitor of kit signal transduction, by activating the critical phosphatidylinositol 3-kinase-akt pathway. |
2005-01-11 |
2023-08-12 |
Not clear |
| Amie S Corbin, Ian J Griswold, Paul La Rosée, Kevin W H Yee, Michael C Heinrich, Corinne L Reimer, Brian J Druker, Michael W N Deininge. Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970. Blood. vol 104. issue 12. 2004-12-30. PMID:15304388. |
mln518 additionally targets active site mutant cell lines, inhibiting cell proliferation, kit, and signal transducer and activator of transcription-3 (stat3) phosphorylation and inducing apoptosis at concentrations that may be clinically achievable. |
2004-12-30 |
2023-08-12 |
Not clear |
| Wings T Y Loo, Mary N B Cheung, Louis W C Cho. The inhibitory effect of a herbal formula comprising ginseng and carthamus tinctorius on breast cancer. Life sciences. vol 76. issue 2. 2004-12-16. PMID:15519364. |
the apoptotic effect was studied by flow cytometry analysis of dna strand breaks and apoptag peroxidase in situ apoptosis kit by the tunel assay. |
2004-12-16 |
2023-08-12 |
human |