| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kemin Chen, Yongzhong Wei, Gordon C Sharp, Helen Braley-Mulle. Decreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis. Journal of leukocyte biology. vol 81. issue 1. 2007-03-05. PMID:17046971. |
gene and protein expression of inflammatory molecules was examined by rt-pcr and immunostaining, and apoptosis was detected using tunel staining and an apoptosis kit. |
2007-03-05 |
2023-08-12 |
mouse |
| E Bollo, R Guglielmino, S Sant, P Pregel, F Riondato, B Miniscalco, E Cornaglia, C Nebbia, M Dacast. Biochemical, ultrastructural and molecular characterization of the triphenyltin acetate (TPTA)-induced apoptosis in primary cultures of mouse thymocytes. Cell biology and toxicology. vol 22. issue 4. 2007-02-27. PMID:16802106. |
cell aliquots were harvested after 0, 1, 2, 4, and 8 h and the presence of early or late apoptotic phenomena was checked by (a) morphological investigations; (b) spectrophotometric quantification of fragmented dna and agarose gel electrophoresis; (c) cell flow cytofluorometry, using an annexin v-fitc kit; and (d) detection of in situ apoptosis by a colorimetric detection kit (titer-tacs). |
2007-02-27 |
2023-08-12 |
mouse |
| Jingxuan Pan, Alfonso Quintás-Cardama, Hagop M Kantarjian, Cem Akin, Taghi Manshouri, Peter Lamb, Jorge E Cortes, Ayalew Tefferi, Francis J Giles, Srdan Verstovse. EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation. Blood. vol 109. issue 1. 2007-02-20. PMID:16912224. |
exel-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the kit d816v mutation. |
2007-02-20 |
2023-08-12 |
human |
| Christopher Runyan, Kyle Schaible, Kathleen Molyneaux, Zhuoqiao Wang, Linda Levin, Christopher Wyli. Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development (Cambridge, England). vol 133. issue 24. 2007-02-16. PMID:17107997. |
we then show that germ cell apoptosis in the midline is activated by down-regulation of steel factor (kit ligand) expression in the midline between e9.5 and e10.5. |
2007-02-16 |
2023-08-12 |
mouse |
| Songde Cho, Yasuhiko Kitadai, Shigeto Yoshida, Shinji Tanaka, Masaharu Yoshihara, Kazuhiro Yoshida, Kazuaki Chayam. Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions. International journal of molecular medicine. vol 18. issue 6. 2007-01-23. PMID:17089009. |
immunohistochemistry was performed for kit, cd34, ki-67 (as a marker of cell proliferation), and cd31 (as a marker of microvessel density), and apoptosis was assessed by in situ dna nick end-labeling. |
2007-01-23 |
2023-08-12 |
Not clear |
| Selim Corbacioglu, Mehtap Kilic, Mike-Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus-Michael Debati. Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin. Blood. vol 108. issue 10. 2007-01-09. PMID:16840725. |
kit citd induced factorindependent growth and apoptosis resistance, and exhibited constitutive autophosphorylation. |
2007-01-09 |
2023-08-12 |
human |
| Selim Corbacioglu, Mehtap Kilic, Mike-Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus-Michael Debati. Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin. Blood. vol 108. issue 10. 2007-01-09. PMID:16840725. |
im and rap synergistically inhibited growth and surmounted kit citd-induced apoptosis resistance. |
2007-01-09 |
2023-08-12 |
human |
| L Lo Muzio, A Santarelli, M Emanuelli, F Pierella, D Sartini, S Staibano, C Rubini, G De Ros. Genetic analysis of oral squamous cell carcinoma by cDNA microarrays focused apoptotic pathway. International journal of immunopathology and pharmacology. vol 19. issue 3. 2006-11-27. PMID:17026852. |
the mrna extracted from these specimens was converted into cdna and analyzed with superarray gearray q series human apoptosis gene array kit. |
2006-11-27 |
2023-08-12 |
human |
| Ewa Olszewska, Stanislaw Chodynicki, Lech Chyczewsk. Apoptosis in the pathogenesis of cholesteatoma in adults. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 263. issue 5. 2006-10-26. PMID:16378223. |
the membstain apoptosis kit direct based on in situ labeling of nuclear dna fragmentation (tolt-mediated dutp nick and labeling tunel staining) was used. |
2006-10-26 |
2023-08-12 |
Not clear |
| Rongshan Li, Tao Ding, Xiaocheng Liu, Caixia L. Influence of SB203580 on cell apoptosis and P38MAPK in renal ischemia/reperfusion injury. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 1. 2006-10-13. PMID:16711007. |
the apoptosis was detected with tunel kit. |
2006-10-13 |
2023-08-12 |
rat |
| Wenjuan Yu, Qing Rao, Min Wang, Zheng Tian, Dong Lin, Xiangrong Liu, Jianxiang Wan. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level. Leukemia research. vol 30. issue 5. 2006-08-31. PMID:16213582. |
the hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of kasumi-1 harboring the asn822lys kit mutation and down-regulates kit protein level. |
2006-08-31 |
2023-08-12 |
Not clear |
| Wenjuan Yu, Qing Rao, Min Wang, Zheng Tian, Dong Lin, Xiangrong Liu, Jianxiang Wan. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level. Leukemia research. vol 30. issue 5. 2006-08-31. PMID:16213582. |
significantly, 17-aag-induced apoptosis of kasumi-1 cells is associated with a decline in kit protein level. |
2006-08-31 |
2023-08-12 |
Not clear |
| Cheng-Hsun Wu, Hui-Hsuan Lin, Fu-Pin Yan, Cheng-Hua Wu, Chau-Jong Wan. Immunohistochemical detection of apoptotic proteins, p53/Bax and JNK/FasL cascade, in the lung of rats exposed to cigarette smoke. Archives of toxicology. vol 80. issue 6. 2006-08-31. PMID:16341695. |
using an in situ cell death detection kit (ta300), the association of cs with apoptosis was determined in a concentration-dependent manner. |
2006-08-31 |
2023-08-12 |
rat |
| Songde Cho, Yasuhiko Kitadai, Shigeto Yoshida, Shinji Tanaka, Masaharu Yoshihara, Kazuhiro Yoshida, Kazuaki Chayam. Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach. International journal of oncology. vol 28. issue 6. 2006-08-16. PMID:16685437. |
immunohistochemistry was performed for kit, cd34, ki-67 (as a marker of cell proliferation) and cd31 (as a marker of microvessel density), and apoptosis was assessed by in situ dna nick-end labeling. |
2006-08-16 |
2023-08-12 |
Not clear |
| Elliot B Sambol, Grazia Ambrosini, Rula C Geha, Peter T Kennealey, Penelope Decarolis, Rachael O'connor, Yuhsin V Wu, Monica Motwani, Jin-Hong Chen, Gary K Schwartz, Samuel Singe. Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells. Cancer research. vol 66. issue 11. 2006-07-27. PMID:16740725. |
this is followed at 24 hours by the transcriptional suppression of kit resulting in poly(adp-ribose) polymerase cleavage and apoptosis. |
2006-07-27 |
2023-08-12 |
Not clear |
| Elliot B Sambol, Grazia Ambrosini, Rula C Geha, Peter T Kennealey, Penelope Decarolis, Rachael O'connor, Yuhsin V Wu, Monica Motwani, Jin-Hong Chen, Gary K Schwartz, Samuel Singe. Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells. Cancer research. vol 66. issue 11. 2006-07-27. PMID:16740725. |
results show that focused suppression of kit alone is sufficient to induce apoptosis in gist cells, but not to the same extent as flavopiridol. |
2006-07-27 |
2023-08-12 |
Not clear |
| Elliot B Sambol, Grazia Ambrosini, Rula C Geha, Peter T Kennealey, Penelope Decarolis, Rachael O'connor, Yuhsin V Wu, Monica Motwani, Jin-Hong Chen, Gary K Schwartz, Samuel Singe. Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells. Cancer research. vol 66. issue 11. 2006-07-27. PMID:16740725. |
in contrast, imatinib mesylate, which inhibits kit kinase activity but does not suppress total kit expression, fails to cause apoptosis. |
2006-07-27 |
2023-08-12 |
Not clear |
| Elliot B Sambol, Grazia Ambrosini, Rula C Geha, Peter T Kennealey, Penelope Decarolis, Rachael O'connor, Yuhsin V Wu, Monica Motwani, Jin-Hong Chen, Gary K Schwartz, Samuel Singe. Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells. Cancer research. vol 66. issue 11. 2006-07-27. PMID:16740725. |
our results indicate that targeting kit expression and these antiapoptotic proteins with flavopiridol represents a novel means to disrupt gist cell dependence on kit signaling and collectively renders these cells sensitive to apoptosis. |
2006-07-27 |
2023-08-12 |
Not clear |
| Chi Tarn, Yuliya V Skorobogatko, Takahiro Taguchi, Burton Eisenberg, Margaret von Mehren, Andrew K Godwi. Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms. Cancer research. vol 66. issue 10. 2006-07-18. PMID:16707477. |
imatinib treatment markedly reduces glucose uptake via decreased levels of plasma membrane-bound glut4 and induces apoptosis or growth arrest by inhibiting kit activity. |
2006-07-18 |
2023-08-12 |
Not clear |
| Musalmah Mazlan, Then Sue Mian, Gapor Mat Top, Wan Zurinah Wan Nga. Comparative effects of alpha-tocopherol and gamma-tocotrienol against hydrogen peroxide induced apoptosis on primary-cultured astrocytes. Journal of the neurological sciences. vol 243. issue 1-2. 2006-06-01. PMID:16442562. |
primary astrocyte cultures were pretreated with either alpha-tocopherol or gamma-tocotrienol for 1 h before incubation with 100 microm h(2)o(2) for 24 h. cell viability was then assessed using the mts assay while apoptosis was determined using a commercial elisa kit as well as by fluorescent staining of live and apoptotic cells. |
2006-06-01 |
2023-08-12 |
Not clear |