| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiangqin Li, Tianqing Liu, Kedong Song, Shui Guan, Leilei Zhu, Dan Ge, Zhanfeng Cu. Effect of neural stem cells on apoptosis of PC12 cells induced by serum deprivation. Biotechnology progress. vol 23. issue 4. 2007-10-09. PMID:17585776. |
in addition, the concentrations of glial derived neurotrophic factor (gdnf) in different medium were detected with a gdnf elisa kit, and the mechanism of nsc's protective effect on pc12 cell apoptosis induced by serum deprivation was analyzed. |
2007-10-09 |
2023-08-12 |
Not clear |
| Jingxuan Pan, Alfonso Quintás-Cardama, Taghi Manshouri, Jorge Cortes, Hagop Kantarjian, Srdan Verstovse. Sensitivity of human cells bearing oncogenic mutant kit isoforms to the novel tyrosine kinase inhibitor INNO-406. Cancer science. vol 98. issue 8. 2007-10-01. PMID:17517053. |
human mast cell (hmc)-1.1 cells with juxtamembrane domain mutation v560g, and hmc-1.2 cells with both v560g and the kinase domain mutation d816v, were treated with inno-406 (0.02-5.00 microm) or imatinib for 72 h. inno-406 and imatinib were equipotent against hmc-1 cells regarding cell proliferation (ic50 51 nm and 75 nm, respectively), inhibition of kit phosphorylation, and induction of apoptosis. |
2007-10-01 |
2023-08-12 |
human |
| Jiusong Sun, Galina K Sukhova, Paul J Wolters, Min Yang, Shiro Kitamoto, Peter Libby, Lindsey A MacFarlane, Jon Mallen-St Clair, Guo-Ping Sh. Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nature medicine. vol 13. issue 6. 2007-08-13. PMID:17546038. |
atheromata from compound mutant ldlr(-/-) kit(w-sh)(/w-sh) mice showed decreased lesion size, lipid deposition, t-cell and macrophage numbers, cell proliferation and apoptosis, but increased collagen content and fibrous cap development. |
2007-08-13 |
2023-08-12 |
mouse |
| O H Ozturk, H Bozcuk, D Burgucu, D Ekinci, M Ozdogan, S Akca, M Yildi. Cisplatin cytotoxicity is enhanced with zoledronic acid in A549 lung cancer cell line: preliminary results of an in vitro study. Cell biology international. vol 31. issue 9. 2007-08-01. PMID:17418595. |
a significant portion of cells underwent apoptosis with or without zoledronic acid, but more so with the combination treatment as assessed by an annexin v-fitc apoptosis detection kit. |
2007-08-01 |
2023-08-12 |
Not clear |
| O Kosmider, N Denis, P Dubreuil, F Moreau-Gacheli. Semaxinib (SU5416) as a therapeutic agent targeting oncogenic Kit mutants resistant to imatinib mesylate. Oncogene. vol 26. issue 26. 2007-07-09. PMID:17173066. |
using these cells in vitro, we demonstrate that the tyrosine kinase inhibitor su5416 (semaxinib) induces growth arrest and apoptosis independent of the mutation type by inhibiting the functions of kit, including kit autophosphorylation and activation of akt, erk1/erk2 and stat3 downstream signaling pathways. |
2007-07-09 |
2023-08-12 |
mouse |
| Francesco Marotta, Masatoshi Harada, Khean-Lee Goh, Aldo Lorenzetti, Paolo Marandola, Emilio Minell. In vitro study on the mechanisms of action of a novel phytotherapeutic compound against human hepatoma cells. Annals of hepatology. vol 6. issue 2. 2007-07-05. PMID:17519835. |
after exponential growth phase hepg2 cells were treated with different doses of yhk and apoptosis was assessed by using an annexin v-fitc kit. |
2007-07-05 |
2023-08-12 |
human |
| Anu Bashamboo, A Helen Taylor, Kay Samuel, Jean-Jacque Panthier, Anthony D Whetton, Lesley M Forreste. The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway. Journal of cell science. vol 119. issue Pt 15. 2007-05-16. PMID:16820414. |
differentiating kit null es cells exhibit elevated levels of dna laddering and reduced bcl2 expression, indicative of apoptosis. |
2007-05-16 |
2023-08-12 |
mouse |
| Miroslav Barancík, Vierka Bohácová, Ján Sedlák, Zdenka Sulová, Albert Breie. LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 29. issue 5. 2007-03-05. PMID:17010577. |
facs analysis of the proportion of cells in apoptosis or necrosis by annexin-v apoptosis kit showed the following: (i) vincristine-induced apoptosis in resistant cell to a much lower extent than in sensitive cells; (ii) ly294,002 alone did not induce apoptosis or necrosis in both sensitive and resistant cells; (iii) ly294,002 applied together with vincristine significantly increased the number of apoptotic cells. |
2007-03-05 |
2023-08-12 |
mouse |
| Kemin Chen, Yongzhong Wei, Gordon C Sharp, Helen Braley-Mulle. Decreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis. Journal of leukocyte biology. vol 81. issue 1. 2007-03-05. PMID:17046971. |
gene and protein expression of inflammatory molecules was examined by rt-pcr and immunostaining, and apoptosis was detected using tunel staining and an apoptosis kit. |
2007-03-05 |
2023-08-12 |
mouse |
| E Bollo, R Guglielmino, S Sant, P Pregel, F Riondato, B Miniscalco, E Cornaglia, C Nebbia, M Dacast. Biochemical, ultrastructural and molecular characterization of the triphenyltin acetate (TPTA)-induced apoptosis in primary cultures of mouse thymocytes. Cell biology and toxicology. vol 22. issue 4. 2007-02-27. PMID:16802106. |
cell aliquots were harvested after 0, 1, 2, 4, and 8 h and the presence of early or late apoptotic phenomena was checked by (a) morphological investigations; (b) spectrophotometric quantification of fragmented dna and agarose gel electrophoresis; (c) cell flow cytofluorometry, using an annexin v-fitc kit; and (d) detection of in situ apoptosis by a colorimetric detection kit (titer-tacs). |
2007-02-27 |
2023-08-12 |
mouse |
| Jingxuan Pan, Alfonso Quintás-Cardama, Hagop M Kantarjian, Cem Akin, Taghi Manshouri, Peter Lamb, Jorge E Cortes, Ayalew Tefferi, Francis J Giles, Srdan Verstovse. EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation. Blood. vol 109. issue 1. 2007-02-20. PMID:16912224. |
exel-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the kit d816v mutation. |
2007-02-20 |
2023-08-12 |
human |
| Christopher Runyan, Kyle Schaible, Kathleen Molyneaux, Zhuoqiao Wang, Linda Levin, Christopher Wyli. Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development (Cambridge, England). vol 133. issue 24. 2007-02-16. PMID:17107997. |
we then show that germ cell apoptosis in the midline is activated by down-regulation of steel factor (kit ligand) expression in the midline between e9.5 and e10.5. |
2007-02-16 |
2023-08-12 |
mouse |
| Songde Cho, Yasuhiko Kitadai, Shigeto Yoshida, Shinji Tanaka, Masaharu Yoshihara, Kazuhiro Yoshida, Kazuaki Chayam. Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions. International journal of molecular medicine. vol 18. issue 6. 2007-01-23. PMID:17089009. |
immunohistochemistry was performed for kit, cd34, ki-67 (as a marker of cell proliferation), and cd31 (as a marker of microvessel density), and apoptosis was assessed by in situ dna nick end-labeling. |
2007-01-23 |
2023-08-12 |
Not clear |
| Selim Corbacioglu, Mehtap Kilic, Mike-Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus-Michael Debati. Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin. Blood. vol 108. issue 10. 2007-01-09. PMID:16840725. |
kit citd induced factorindependent growth and apoptosis resistance, and exhibited constitutive autophosphorylation. |
2007-01-09 |
2023-08-12 |
human |
| Selim Corbacioglu, Mehtap Kilic, Mike-Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus-Michael Debati. Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin. Blood. vol 108. issue 10. 2007-01-09. PMID:16840725. |
im and rap synergistically inhibited growth and surmounted kit citd-induced apoptosis resistance. |
2007-01-09 |
2023-08-12 |
human |
| L Lo Muzio, A Santarelli, M Emanuelli, F Pierella, D Sartini, S Staibano, C Rubini, G De Ros. Genetic analysis of oral squamous cell carcinoma by cDNA microarrays focused apoptotic pathway. International journal of immunopathology and pharmacology. vol 19. issue 3. 2006-11-27. PMID:17026852. |
the mrna extracted from these specimens was converted into cdna and analyzed with superarray gearray q series human apoptosis gene array kit. |
2006-11-27 |
2023-08-12 |
human |
| Ewa Olszewska, Stanislaw Chodynicki, Lech Chyczewsk. Apoptosis in the pathogenesis of cholesteatoma in adults. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 263. issue 5. 2006-10-26. PMID:16378223. |
the membstain apoptosis kit direct based on in situ labeling of nuclear dna fragmentation (tolt-mediated dutp nick and labeling tunel staining) was used. |
2006-10-26 |
2023-08-12 |
Not clear |
| Rongshan Li, Tao Ding, Xiaocheng Liu, Caixia L. Influence of SB203580 on cell apoptosis and P38MAPK in renal ischemia/reperfusion injury. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 1. 2006-10-13. PMID:16711007. |
the apoptosis was detected with tunel kit. |
2006-10-13 |
2023-08-12 |
rat |
| Wenjuan Yu, Qing Rao, Min Wang, Zheng Tian, Dong Lin, Xiangrong Liu, Jianxiang Wan. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level. Leukemia research. vol 30. issue 5. 2006-08-31. PMID:16213582. |
the hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of kasumi-1 harboring the asn822lys kit mutation and down-regulates kit protein level. |
2006-08-31 |
2023-08-12 |
Not clear |
| Wenjuan Yu, Qing Rao, Min Wang, Zheng Tian, Dong Lin, Xiangrong Liu, Jianxiang Wan. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level. Leukemia research. vol 30. issue 5. 2006-08-31. PMID:16213582. |
significantly, 17-aag-induced apoptosis of kasumi-1 cells is associated with a decline in kit protein level. |
2006-08-31 |
2023-08-12 |
Not clear |