| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefan Faderl, Ashutosh Pal, William Bornmann, Maher Albitar, David Maxwell, Quin Van, Zhenghong Peng, David Harris, Zhiming Liu, Inbal Hazan-Halevy, Hagop M Kantarjian, Zeev Estro. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer research. vol 69. issue 9. 2009-07-14. PMID:19383925. |
kit inhibitor apck110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. |
2009-07-14 |
2023-08-12 |
Not clear |
| Stefan Faderl, Ashutosh Pal, William Bornmann, Maher Albitar, David Maxwell, Quin Van, Zhenghong Peng, David Harris, Zhiming Liu, Inbal Hazan-Halevy, Hagop M Kantarjian, Zeev Estro. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer research. vol 69. issue 9. 2009-07-14. PMID:19383925. |
we show that (a) apck110 inhibits proliferation of the mastocytosis cell line hmc1.2 and the scf-responsive cell line oci/aml3 in a dose-dependent manner; (b) apck110 is a more potent inhibitor of oci/aml3 proliferation than the clinically used kit inhibitors imatinib and dasatinib and at least as potent as cytarabine; (c) apck110 inhibits the phosphorylation of kit, stat3, stat5, and akt in a dose-dependent fashion, showing activity of apck110 on kit and its downstream signaling pathways; (d) apck110 induces apoptosis by cleavage of caspase-3 and poly(adp-ribose) polymerase; and (e) apck110 inhibits proliferation of primary aml blasts in a clonogenic assay but does not affect proliferation of normal colony-forming cells. |
2009-07-14 |
2023-08-12 |
Not clear |
| T Matijevic, M Marjanovic, J Paveli. Functionally active toll-like receptor 3 on human primary and metastatic cancer cells. Scandinavian journal of immunology. vol 70. issue 1. 2009-07-07. PMID:19522763. |
by using annexin-v apoptosis detection kit, we have found that poly i:c triggers apoptosis in detroit 562 cell line. |
2009-07-07 |
2023-08-12 |
human |
| Yue Wu, Melissa Fabritius, Clement I. Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer. Cancer biology & therapy. vol 8. issue 2. 2009-06-15. PMID:19182512. |
the efficacy of single drug and the various combinations was evaluated by measuring apoptosis with a cell death elisa kit. |
2009-06-15 |
2023-08-12 |
human |
| Hong-Tao Liu, Wen-Ming Li, Gang Xu, Xiu-Ying Li, Xue-Fang Bai, Peng Wei, Chao Yu, Yu-Guang D. Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells. Pharmacological research. vol 59. issue 3. 2009-04-23. PMID:19121394. |
in addition, pre-incubation of cos with ecv304 cells for 24h resulted in the reduction of apoptosis and the induction of cell cycle arrest in g(1)/s+m phase as assayed quantitatively by annexin v-fluorescein isothiocyanate (fitc) apoptosis detection kit using flow cytometry. |
2009-04-23 |
2023-08-12 |
human |
| Celalettin Ustun, Christopher L Corless, Natasha Savage, Warren Fiskus, Elizabeth Manaloor, Michael C Heinrich, Grant Lewis, Preetha Ramalingam, Ilana Kepten, Anand Jillella, Kapil Bhall. Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V. Leukemia research. vol 33. issue 5. 2009-04-06. PMID:18986703. |
additionally, dasatinib induced apoptosis in mast cell and leukemia cell lines expressing kit(d816v). |
2009-04-06 |
2023-08-12 |
Not clear |
| Wen Jian, Zhao Wei, Cheng Zhiqiang, Fang Zhen. X-ray-induced apoptosis of BEL-7402 cell line enhanced by extremely low frequency electromagnetic field in vitro. Bioelectromagnetics. vol 30. issue 2. 2009-03-30. PMID:19051321. |
apoptosis rates of bel-7402 cells were analyzed using annexin v-fit apoptosis detection kit. |
2009-03-30 |
2023-08-12 |
Not clear |
| M J Siemieniuch, I Woclawek-Potock. Assessment of selected quality parameters of epididymal cat (Felis catus s. domestica, L. 1758) sperm using flow cytometry method and computer assisted sperm analyser. Reproduction in domestic animals = Zuchthygiene. vol 43. issue 5. 2009-02-09. PMID:18363605. |
the samples were assessed for sperm viability (live/dead sperm viability kit), percentage of subtle membrane changes (apoptosis detection kit) and motility using facscalibur flow cytometer and assisted sperm analyser htm ivos version 12.2. |
2009-02-09 |
2023-08-12 |
cat |
| M J Siemieniuch, I Woclawek-Potock. Assessment of selected quality parameters of epididymal cat (Felis catus s. domestica, L. 1758) sperm using flow cytometry method and computer assisted sperm analyser. Reproduction in domestic animals = Zuchthygiene. vol 43. issue 5. 2009-02-09. PMID:18363605. |
the flow cytometry method revealed 71.3% and 84.4% of live sperm using live/dead sperm viability kit and apoptosis detection kit respectively. |
2009-02-09 |
2023-08-12 |
cat |
| M J Siemieniuch, I Woclawek-Potock. Assessment of selected quality parameters of epididymal cat (Felis catus s. domestica, L. 1758) sperm using flow cytometry method and computer assisted sperm analyser. Reproduction in domestic animals = Zuchthygiene. vol 43. issue 5. 2009-02-09. PMID:18363605. |
the data revealed an indistinctive per cent of apoptotic cells and 18.9% and 15.6% of dead cells using live/dead sperm viability kit and apoptosis detection kit, respectively, which indicate that the sperm obtained after flushing the epididymis possess potential properties for further assisted reproduction techniques. |
2009-02-09 |
2023-08-12 |
cat |
| Hangping Yao, Xiajing Tang, Xueting Shao, Lei Feng, Nanping Wu, Ke Ya. Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9. Cell research. vol 17. issue 6. 2009-01-21. PMID:17339884. |
to study apoptosis, the cells were assessed by morphologic examination and annexin v-propidium iodide double staining flow cytometry; to investigate the underlying molecular mechanisms, the expression of caspase-3 and caspase-9 were assayed by western blot and quantitative rt-pcr, and the activities of caspase-3 and caspase-9 were measured by a chemicon caspase colorimetric activity assay kit. |
2009-01-21 |
2023-08-12 |
human |
| Audrey Varin, Anis Larbi, George V Dedoussis, Stavroula Kanoni, Jolanta Jajte, Lothar Rink, Daniela Monti, Marco Malavolta, Fiorella Marcellini, Eugenio Mocchegiani, Georges Herbein, Tamas Fulo. In vitro and in vivo effects of zinc on cytokine signalling in human T cells. Experimental gerontology. vol 43. issue 5. 2008-12-04. PMID:18249079. |
the activation induced cell death (aicd) was measured after anti-cd3 and cd28 restimulation for 48h by using the annexin:fitc apoptosis kit. |
2008-12-04 |
2023-08-12 |
human |
| Suk-Ching Lee, Wing-Ki Chan, Tak-Wing Lee, Wai-Har Lam, Xianghong Wang, Tak-Hang Chan, Yong-Chuan Won. Effect of a prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate on the growth of androgen-independent prostate cancer in vivo. Nutrition and cancer. vol 60. issue 4. 2008-11-10. PMID:18584482. |
the apoptotic effect was evaluated by ihc against b-cell non-hodgkin lymphoma-2 and terminal deoxynucleotidyl transferase dutp nick-end labeling assay by in situ apoptosis detection kit. |
2008-11-10 |
2023-08-12 |
mouse |
| M Waheed Roomi, Tatiana Kalinovsky, Nusrath W Roomi, Vadim Ivanov, Matthias Rath, Aleksandra Niedzwieck. Suppression of growth and hepatic metastasis of murine B16FO melanoma cells by a novel nutrient mixture. Oncology reports. vol 20. issue 4. 2008-11-04. PMID:18813822. |
to confirm effects in vivo, we investigated the effect of nm on murine b16fo melanoma cells in vitro, including cell proliferation by mtt assay, morphology by hematoxylin and eosin (h&e) staining and apoptosis using live green caspase detection kit. |
2008-11-04 |
2023-08-12 |
mouse |
| Lifeng Yang, Xiangmei Zhou, Jianmin Yang, Xiaomin Yin, Lifang Han, Deming Zha. Aspirin inhibits cytotoxicity of prion peptide PrP106-126 to neuronal cells associated with microglia activation in vitro. Journal of neuroimmunology. vol 199. issue 1-2. 2008-10-14. PMID:18547651. |
inhibitory activity of aspirin on neurotoxicity of prp106-126 associated with microglia activation was determined using an apoptosis detection kit. |
2008-10-14 |
2023-08-12 |
human |
| Qing-Shan Yang, Jin-Long Gu, Li-Qing Du, Li-Li Jia, Li-Li Qin, Yong Wang, Fei-Yue Fa. ShRNA-mediated Ku80 gene silencing inhibits cell proliferation and sensitizes to gamma-radiation and mitomycin C-induced apoptosis in esophageal squamous cell carcinoma lines. Journal of radiation research. vol 49. issue 4. 2008-09-16. PMID:18403903. |
apoptosis induced by gamma-radiation and mmc was analyzed using genmed-tunel facs kit. |
2008-09-16 |
2023-08-12 |
human |
| Jing Fang, Madhu Menon, Diya Zhang, Bruce Torbett, Leif Oxburgh, Mario Tschan, Estelle Houde, Don M Wojchowsk. Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2. Blood. vol 112. issue 3. 2008-09-05. PMID:18535204. |
ex vivo ana-lyses revealed heightened apoptosis due to dapk2 at a kit(-)cd71(high)ter119(-) stage, together with a subsequent multifold defect in late-stage kit(-)cd71(high)ter119(+) cell formation. |
2008-09-05 |
2023-08-12 |
mouse |
| Marta Siemieniuch, Andrzej Dubie. Preservation of tomcat (Felis catus) semen in variable temperatures. Animal reproduction science. vol 99. issue 1-2. 2008-08-29. PMID:16725286. |
the usage of apoptosis detection kit revealed, that the percentage of early-apoptotic and late-apoptotic cells was insignificant. |
2008-08-29 |
2023-08-12 |
cat |
| Mónica M Chamorro, John D Regan, Lynne A Opperman, Phillip R Krame. Effect of storage media on human periodontal ligament cell apoptosis. Dental traumatology : official publication of International Association for Dental Traumatology. vol 24. issue 1. 2008-04-25. PMID:18173658. |
apoptosis was evaluated at 24, 48, and 72 h after treatment on quadruplicate samples by using the st 160 apoptag fluorescein direct in situ detection kit. |
2008-04-25 |
2023-08-12 |
human |
| XiaoFeng Zhang, BaiXiang Li, Yang Zhang, JiaRen Li. Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells. Science in China. Series C, Life sciences. vol 51. issue 1. 2008-04-04. PMID:18176793. |
subcellular fractions were extracted by mitochondrial/cytosol fractionation kit after c(2)-ceramide treatment for 24 h. sds-page was used to determine the level of cytochrome c (cyt c), high temperature requirement a2 (htra2) and second mitochondrial-derived activator of caspases (smac) released from mitochondria, the expression of x-linked inhibitor of apoptosis protein (xiap) and caspase-3 for 24 h. the results showed that deltaphi(m) began to decrease from 6 h after 25 and 50 micromol/l c(2)-ceramide treatment (p<0.05) and cyclosporin a (csa) could inhibit the collapse of deltaphi(m) through regulating mitochondrial membrane permeability transition pore. |
2008-04-04 |
2023-08-12 |
human |