| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanli Jin, Zhongzheng Lu, Kaiyuan Cao, Yunhui Zhu, Qi Chen, Feng Zhu, Chenchen Qian, Jingxuan Pa. The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutation. Molecular cancer therapeutics. vol 9. issue 1. 2010-03-22. PMID:20053766. |
imatinib-sensitive hmc-1.1 cells harboring the mutation v560g in the juxtamembrane domain of kit, imatinib-resistant hmc-1.2 cells harboring both v560g and d816v mutations, and murine p815 cells were treated with hht and analyzed in terms of growth, apoptosis, and signal transduction. |
2010-03-22 |
2023-08-12 |
mouse |
| Yanli Jin, Zhongzheng Lu, Kaiyuan Cao, Yunhui Zhu, Qi Chen, Feng Zhu, Chenchen Qian, Jingxuan Pa. The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutation. Molecular cancer therapeutics. vol 9. issue 1. 2010-03-22. PMID:20053766. |
our results indicated that hht effectively inhibited the growth and induced apoptosis in cells bearing both v560g and d816v or d814y kit. |
2010-03-22 |
2023-08-12 |
mouse |
| Hui Liu, Tiantuo Zhang, Benquan Wu, Jing Huang, Yuqi Zhou, Jiaxin Zh. Chronic exposure to exogenous matrilysin induces chemoresistance and enhances Bcl-2 expression in A549 lung adenocarcinoma cells. Molecular biology reports. vol 36. issue 8. 2010-02-02. PMID:19107575. |
the viability of a549 lung adenocarcinoma cells was determinated by mtt and the apoptosis was assessed by hoechst 33342 staining and annexin v-fitc/pi apoptosis kit. |
2010-02-02 |
2023-08-12 |
Not clear |
| Fen Guo, Zhi-Wen Luo, Zhao-Yu Liu, Yue-Qin Li, Hong-Jian Li, Tian-Hong Zho. [Studies of effect of prosaposin on cell proliferation, cell apoptosis and its possible molecular mechanism]. Yi chuan = Hereditas. vol 31. issue 12. 2010-02-01. PMID:20042390. |
mtt assay and annexin v/pi apoptosis kit were used to detect the effect of prosaposin on cell proliferation and cell apoptosis induced by se-rum-starvation stress, respectively. |
2010-02-01 |
2023-08-12 |
Not clear |
| Sebastian Bauer, Joshua A Parry, Thomas Mühlenberg, Matthew F Brown, Danushka Seneviratne, Payel Chatterjee, Anna Chin, Brian P Rubin, Shih-Fan Kuan, Jonathan A Fletcher, Stefan Duensing, Anette Duensin. Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells. Cancer research. vol 70. issue 1. 2010-01-26. PMID:20028860. |
we show that bortezomib rapidly triggers apoptosis in gist cells through a combination of mechanisms involving h2ax upregulation and loss of kit protein expression. |
2010-01-26 |
2023-08-12 |
Not clear |
| Xue-Lan Zuo, Ying Zhou, Rui-Fang Li, Ying-Qian Feng, Li He, Ming-Hui Li. [Relation of apoptosis of K562 cells induced by naringenin in vitro to enzyme activity changes of caspase-3 and caspase-8 and expression of FAS/FASL proteins]. Zhongguo shi yan xue ye xue za zhi. vol 16. issue 2. 2010-01-21. PMID:18426650. |
the inhibition of ngen on k562 cells was evaluated by means of mtt assay so as to observe the cytotoxicity of ngen; the morphological changes of the cells treated by ngen were observed by transmission electron microscope; cell apoptosis rate influenced by ngen was assessed by flow cytometry; the enzyme activity changes of caspase-3 and caspase-8 in the process of ngen-induced k562 apoptosis were detected by caspase colorimetric assay kit; immunohistochemistry technique was used to detect fas, fasl protein expression in k562 cells. |
2010-01-21 |
2023-08-12 |
Not clear |
| Z Jovic, M Veselinovic, K Vasic, D Stankovic-Djordjevic, S Cekic, M Milovanovic, M Sara. Monosodium glutamate induces apoptosis in naive and memory human B cells. Bratislavske lekarske listy. vol 110. issue 10. 2010-01-12. PMID:20017456. |
detection of apoptosis by flow cytometry was performed using the annexin v-fitc/propidium iodide (pi) apoptosis detection kit. |
2010-01-12 |
2023-08-12 |
human |
| S Giorgadze, N Gujabidze, N Tevzadze, R Rukhadz. Apoptosis and proliferative activity of hepatocytes of white rats during aging. Georgian medical news. issue 174. 2009-12-17. PMID:19801741. |
apoptosis was detected in liver sections by the in situ oligo ligation (isol) assay, using an apoptag isol assay kit. |
2009-12-17 |
2023-08-12 |
rat |
| Thomas Mühlenberg, Yixiang Zhang, Andrew J Wagner, Florian Grabellus, James Bradner, Georg Taeger, Hauke Lang, Takahiro Taguchi, Martin Schuler, Jonathan A Fletcher, Sebastian Baue. Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors. Cancer research. vol 69. issue 17. 2009-11-17. PMID:19706776. |
inhibitors of deacetylases suppress oncogenic kit signaling, acetylate hsp90, and induce apoptosis in gastrointestinal stromal tumors. |
2009-11-17 |
2023-08-12 |
Not clear |
| Matthias Schefzyk, Manuela Bruder, Andreas Schmiedl, Michael Stephan, Alexander Kapp, Bettina Wedi, Ulrike Raa. Eosinophil granulocytes: functional differences of a new isolation kit compared to the isolation with anti-CD16-conjugated MicroBeads. Experimental dermatology. vol 18. issue 7. 2009-10-23. PMID:19196345. |
using a new eosinophil isolation kit, we were not able to confirm our previous findings of a delayed apoptosis of eosinophils in atopic dermatitis. |
2009-10-23 |
2023-08-12 |
Not clear |
| Roma A Girón, Luis F Montaño, María L Escobar, Rebeca López-Marur. Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism. The FEBS journal. vol 276. issue 19. 2009-10-22. PMID:19702826. |
flow cytometry was used to evaluate the phases of the cell cycle, and cell death was detected using a commercially available carboxyfluorescein apoptosis detection kit that determines caspase activation. |
2009-10-22 |
2023-08-12 |
human |
| Ermelindo C Leal, Célia A Aveleira, Aurea F Castilho, Andreia M Serra, Filipa I Baptista, Ken-Ichi Hosoya, John V Forrester, António F Ambrósi. High glucose and oxidative/nitrosative stress conditions induce apoptosis in retinal endothelial cells by a caspase-independent pathway. Experimental eye research. vol 88. issue 5. 2009-10-08. PMID:19146853. |
active caspases were detected by an apoptosis detection kit. |
2009-10-08 |
2023-08-12 |
rat |
| Elisa Tinazzi, Antonio Puccetti, Roberto Gerli, Antonella Rigo, Paola Migliorini, Sara Simeoni, Ruggero Beri, Marzia Dolcino, Nicola Martinelli, Roberto Corrocher, Claudio Lunard. Serum DNase I, soluble Fas/FasL levels and cell surface Fas expression in patients with SLE: a possible explanation for the lack of efficacy of hrDNase I treatment. International immunology. vol 21. issue 3. 2009-10-07. PMID:19181929. |
apoptosis was studied by means of internucleosomal dna degradation using a commercially available kit. |
2009-10-07 |
2023-08-12 |
human |
| Yanli Jin, Qi Chen, Xianping Shi, Zhongzheng Lu, Chao Cheng, Yingrong Lai, Qin Zheng, Jingxuan Pa. Activity of triptolide against human mast cells harboring the kinase domain mutant KIT. Cancer science. vol 100. issue 7. 2009-09-09. PMID:19383029. |
imatinib-sensitive hmc-1.1 cells harboring the mutation v560g in the juxtamembrane domain of kit, imatinib-resistant hmc-1.2 cells harboring both v560g and d816v mutations, and murine p815 cells, were treated with triptolide, and analyzed in terms of growth, apoptosis, and signal transduction. |
2009-09-09 |
2023-08-12 |
mouse |
| Yan Chen, Qing Wu, Guo-hui Cui, Yi-quan Chen, Rui L. Deguelin blocks cells survival signal pathways and induces apoptosis of HL-60 cells in vitro. International journal of hematology. vol 89. issue 5. 2009-09-09. PMID:19455392. |
apoptosis was detected by annexin v-fitc apoptosis detection kit and transmission electron microscopy (tem), expression of p-akt, bcl-2 and surviving in hl-60 cells was checked by western blot. |
2009-09-09 |
2023-08-12 |
human |
| Dong-Yun Qin, Ren Huang, Tie W. In vitro arsenic trioxide induces apoptosis in T cells of asthmatic patients by a Bcl-2 related mechanism. Yao xue xue bao = Acta pharmaceutica Sinica. vol 43. issue 1. 2009-08-10. PMID:18357729. |
cell apoptosis was measured using fluorescence microscopy, flow cytometry and a cytochrome c elisa kit. |
2009-08-10 |
2023-08-12 |
Not clear |
| Stefan Faderl, Ashutosh Pal, William Bornmann, Maher Albitar, David Maxwell, Quin Van, Zhenghong Peng, David Harris, Zhiming Liu, Inbal Hazan-Halevy, Hagop M Kantarjian, Zeev Estro. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer research. vol 69. issue 9. 2009-07-14. PMID:19383925. |
kit inhibitor apck110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. |
2009-07-14 |
2023-08-12 |
Not clear |
| Stefan Faderl, Ashutosh Pal, William Bornmann, Maher Albitar, David Maxwell, Quin Van, Zhenghong Peng, David Harris, Zhiming Liu, Inbal Hazan-Halevy, Hagop M Kantarjian, Zeev Estro. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer research. vol 69. issue 9. 2009-07-14. PMID:19383925. |
we show that (a) apck110 inhibits proliferation of the mastocytosis cell line hmc1.2 and the scf-responsive cell line oci/aml3 in a dose-dependent manner; (b) apck110 is a more potent inhibitor of oci/aml3 proliferation than the clinically used kit inhibitors imatinib and dasatinib and at least as potent as cytarabine; (c) apck110 inhibits the phosphorylation of kit, stat3, stat5, and akt in a dose-dependent fashion, showing activity of apck110 on kit and its downstream signaling pathways; (d) apck110 induces apoptosis by cleavage of caspase-3 and poly(adp-ribose) polymerase; and (e) apck110 inhibits proliferation of primary aml blasts in a clonogenic assay but does not affect proliferation of normal colony-forming cells. |
2009-07-14 |
2023-08-12 |
Not clear |
| T Matijevic, M Marjanovic, J Paveli. Functionally active toll-like receptor 3 on human primary and metastatic cancer cells. Scandinavian journal of immunology. vol 70. issue 1. 2009-07-07. PMID:19522763. |
by using annexin-v apoptosis detection kit, we have found that poly i:c triggers apoptosis in detroit 562 cell line. |
2009-07-07 |
2023-08-12 |
human |
| Yue Wu, Melissa Fabritius, Clement I. Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer. Cancer biology & therapy. vol 8. issue 2. 2009-06-15. PMID:19182512. |
the efficacy of single drug and the various combinations was evaluated by measuring apoptosis with a cell death elisa kit. |
2009-06-15 |
2023-08-12 |
human |