| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ronald B George, Jennifer Kalich, Bryan Yonish, Amy P Murth. Apoptosis in the chorion of fetal membranes in preterm premature rupture of membranes. American journal of perinatology. vol 25. issue 1. 2008-03-28. PMID:18075963. |
using the tunel (terminal uridine deoxynucleotidyl transferase dutp nick-end labeling) method (apoptag plus kit; oncor, gaithersburg, md), apoptosis was quantified. |
2008-03-28 |
2023-08-12 |
human |
| Wenzhu Li, Changgong Zhang, Caixia Chen, Guohong Zhuan. Correlation between expression of DcR3 on tumor cells and sensitivity to FasL. Cellular & molecular immunology. vol 4. issue 6. 2008-03-25. PMID:18163957. |
sensitivity to apoptosis induced by fasl was determined by annexin v apoptosis kit. |
2008-03-25 |
2023-08-12 |
Not clear |
| Marco Gabbianelli, Ornella Morsilli, Adriana Massa, Luca Pasquini, Paolo Cianciulli, Ugo Testa, Cesare Peschl. Effective erythropoiesis and HbF reactivation induced by kit ligand in beta-thalassemia. Blood. vol 111. issue 1. 2008-02-15. PMID:17951528. |
here, we investigated the in vitro response of beta-thalassemic erythroid progenitors to kit ligand (kl) in terms of hbf reactivation, stimulation of effective erythropoiesis, and inhibition of apoptosis. |
2008-02-15 |
2023-08-12 |
human |
| b' V Pavlovi\\xc4\\x87, S Ceki\\xc4\\x87, G Koci\\xc4\\x87, D Sokolovi\\xc4\\x87, V Zivkovi\\xc4\\x8. Effect of monosodium glutamate on apoptosis and Bcl-2/Bax protein level in rat thymocyte culture. Physiological research. vol 56. issue 5. 2008-02-14. PMID:17184147.' |
rat thymocytes, obtained from male wistar rats, were exposed to increasing concentrations of msg (ranging from 1 mm to 100 mm) for 24 h. apoptosis was detected using the annexin v-fitc/pi apoptosis detection kit and cells were analyzed using a flow cytometer. |
2008-02-14 |
2023-08-12 |
rat |
| M W Roomi, V Ivanov, T Kalinovsky, Aleksandra Niedzwiecki, M Rat. Inhibition of cell invasion and MMP production by a nutrient mixture in malignant liposarcoma cell line SW-872. Medical oncology (Northwood, London, England). vol 24. issue 4. 2008-02-08. PMID:17917088. |
we investigated the effect of nm on liposarcoma cell line sw-872 proliferation (mtt assay), mmp secretion (gelatinase zymography), invasion through matrigel, and apoptosis and morphology (live green caspase kit and h&e). |
2008-02-08 |
2023-08-12 |
Not clear |
| Yongqing Wei, Beihua Kong, Kun Song, Xun Qu, Qiong Jin, Qifeng Yan. Involvement of mitochondria-caspase pathway in Hemoporfin-mediated cell death. Photochemistry and photobiology. vol 83. issue 6. 2008-02-07. PMID:18028204. |
apoptosis or necrosis was determined by flow cytometry analysis using the annexin v-fitc apoptosis kit. |
2008-02-07 |
2023-08-12 |
human |
| S Bauer, A Duensing, G D Demetri, J A Fletche. KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway. Oncogene. vol 26. issue 54. 2008-01-09. PMID:17546049. |
biological consequences of biochemical inhibition of kit, phosphatidyl-inositol-3-kinase (pi3-k), plcgamma, mapk/erk kinase/mitogen-activated protein kinase (mek/mapk), mammalian target of rapamycin (mtor) and jak were determined by immunoblotting for protein activation, and by cell proliferation and apoptosis assays in gist cell lines from imatinib-sensitive gist (gist882), imatinib-resistant gists (gist430 and gist48) and kit-negative gist (gist62). |
2008-01-09 |
2023-08-12 |
Not clear |
| V G Kravtsov, O V Zaĭrat'iant. [Clinical and morphological characteristics of gastrointestinal stromal tumors]. Arkhiv patologii. vol 69. issue 5. 2007-12-31. PMID:18074824. |
the c-kit gene mutations leading to the expression and autoactivation of the tyrosine kinase receptor kit underlie the oncogenesis of gist, which results in enhanced proliferative activity and inhibited apoptosis. |
2007-12-31 |
2023-08-12 |
Not clear |
| Ling-Bo Liu, Wei-Ming Li, Ping Zou, Wei He, Min Zhan. [Depressing the immune escape of acute myelomonocytic leukemia via an anti-Fas ribozyme]. Zhongguo shi yan xue ye xue za zhi. vol 14. issue 5. 2007-12-20. PMID:17096877. |
the caspase-3 proteolytic activity and the apoptosis rate of ctll-2 cells were detected by means of bd aproalert caspase-3 colorimetric kit and fitc labeled annexin-v apoptosis detecting kit respectively. |
2007-12-20 |
2023-08-12 |
mouse |
| Malcolm A King, Ayad Eddaoudi, Derek C Davie. A comparison of three flow cytometry methods for evaluating mitochondrial damage during staurosporine-induced apoptosis in Jurkat cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology. vol 71. issue 9. 2007-11-28. PMID:17654655. |
apoptosis was triggered in jurkat cells with staurosporine and then flow cytometry was used to measure three aspects of mitochondrial damage: (1) cytochrome c release (with the digitonin assay and a commercially available kit based on the same principle), using a dna-binding dye to define cell cycle stage; (2) loss of mitochondrial cardiolipin, assessed by a decrease in 10 n-nonyl acridine orange (nao) binding; and (3) loss of mitochondrial membrane potential, assessed by a decrease in tetramethylrhodamineethylester (tmre) binding. |
2007-11-28 |
2023-08-12 |
Not clear |
| A Olivieri, L Manzion. Dasatinib: a new step in molecular target therapy. Annals of oncology : official journal of the European Society for Medical Oncology. vol 18 Suppl 6. 2007-11-07. PMID:17591830. |
recently, dasatinib emerged as a potent inhibitor of imatinib-resistant protein tyrosine kinase (kit) activation loop mutants and it is able to induce apoptosis in mast cell and leukemic cell lines expressing these mutations. |
2007-11-07 |
2023-08-12 |
human |
| Z G Fridlender, P Y Cohen, O Golan, N Arish, S Wallach-Dayan, R Breue. Telomerase activity in bleomycin-induced epithelial cell apoptosis and lung fibrosis. The European respiratory journal. vol 30. issue 2. 2007-10-19. PMID:17504800. |
the current authors evaluated changes in murine telomerase reverse transcriptase (mtert) mrna levels and changes in telomerase activity with the trapeze detection kit, telomeric length with the telottaggg telomere length kit, and lec apoptosis with facscan and 4,6-diamino-2-phenylindole dihydrochloride stain. |
2007-10-19 |
2023-08-12 |
mouse |
| Xiangqin Li, Tianqing Liu, Kedong Song, Shui Guan, Leilei Zhu, Dan Ge, Zhanfeng Cu. Effect of neural stem cells on apoptosis of PC12 cells induced by serum deprivation. Biotechnology progress. vol 23. issue 4. 2007-10-09. PMID:17585776. |
in addition, the concentrations of glial derived neurotrophic factor (gdnf) in different medium were detected with a gdnf elisa kit, and the mechanism of nsc's protective effect on pc12 cell apoptosis induced by serum deprivation was analyzed. |
2007-10-09 |
2023-08-12 |
Not clear |
| Jingxuan Pan, Alfonso Quintás-Cardama, Taghi Manshouri, Jorge Cortes, Hagop Kantarjian, Srdan Verstovse. Sensitivity of human cells bearing oncogenic mutant kit isoforms to the novel tyrosine kinase inhibitor INNO-406. Cancer science. vol 98. issue 8. 2007-10-01. PMID:17517053. |
human mast cell (hmc)-1.1 cells with juxtamembrane domain mutation v560g, and hmc-1.2 cells with both v560g and the kinase domain mutation d816v, were treated with inno-406 (0.02-5.00 microm) or imatinib for 72 h. inno-406 and imatinib were equipotent against hmc-1 cells regarding cell proliferation (ic50 51 nm and 75 nm, respectively), inhibition of kit phosphorylation, and induction of apoptosis. |
2007-10-01 |
2023-08-12 |
human |
| Jiusong Sun, Galina K Sukhova, Paul J Wolters, Min Yang, Shiro Kitamoto, Peter Libby, Lindsey A MacFarlane, Jon Mallen-St Clair, Guo-Ping Sh. Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nature medicine. vol 13. issue 6. 2007-08-13. PMID:17546038. |
atheromata from compound mutant ldlr(-/-) kit(w-sh)(/w-sh) mice showed decreased lesion size, lipid deposition, t-cell and macrophage numbers, cell proliferation and apoptosis, but increased collagen content and fibrous cap development. |
2007-08-13 |
2023-08-12 |
mouse |
| O H Ozturk, H Bozcuk, D Burgucu, D Ekinci, M Ozdogan, S Akca, M Yildi. Cisplatin cytotoxicity is enhanced with zoledronic acid in A549 lung cancer cell line: preliminary results of an in vitro study. Cell biology international. vol 31. issue 9. 2007-08-01. PMID:17418595. |
a significant portion of cells underwent apoptosis with or without zoledronic acid, but more so with the combination treatment as assessed by an annexin v-fitc apoptosis detection kit. |
2007-08-01 |
2023-08-12 |
Not clear |
| O Kosmider, N Denis, P Dubreuil, F Moreau-Gacheli. Semaxinib (SU5416) as a therapeutic agent targeting oncogenic Kit mutants resistant to imatinib mesylate. Oncogene. vol 26. issue 26. 2007-07-09. PMID:17173066. |
using these cells in vitro, we demonstrate that the tyrosine kinase inhibitor su5416 (semaxinib) induces growth arrest and apoptosis independent of the mutation type by inhibiting the functions of kit, including kit autophosphorylation and activation of akt, erk1/erk2 and stat3 downstream signaling pathways. |
2007-07-09 |
2023-08-12 |
mouse |
| Francesco Marotta, Masatoshi Harada, Khean-Lee Goh, Aldo Lorenzetti, Paolo Marandola, Emilio Minell. In vitro study on the mechanisms of action of a novel phytotherapeutic compound against human hepatoma cells. Annals of hepatology. vol 6. issue 2. 2007-07-05. PMID:17519835. |
after exponential growth phase hepg2 cells were treated with different doses of yhk and apoptosis was assessed by using an annexin v-fitc kit. |
2007-07-05 |
2023-08-12 |
human |
| Anu Bashamboo, A Helen Taylor, Kay Samuel, Jean-Jacque Panthier, Anthony D Whetton, Lesley M Forreste. The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway. Journal of cell science. vol 119. issue Pt 15. 2007-05-16. PMID:16820414. |
differentiating kit null es cells exhibit elevated levels of dna laddering and reduced bcl2 expression, indicative of apoptosis. |
2007-05-16 |
2023-08-12 |
mouse |
| Miroslav Barancík, Vierka Bohácová, Ján Sedlák, Zdenka Sulová, Albert Breie. LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 29. issue 5. 2007-03-05. PMID:17010577. |
facs analysis of the proportion of cells in apoptosis or necrosis by annexin-v apoptosis kit showed the following: (i) vincristine-induced apoptosis in resistant cell to a much lower extent than in sensitive cells; (ii) ly294,002 alone did not induce apoptosis or necrosis in both sensitive and resistant cells; (iii) ly294,002 applied together with vincristine significantly increased the number of apoptotic cells. |
2007-03-05 |
2023-08-12 |
mouse |