| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nazmiye Bitgen, Mustafa Cakir, Senem Akkoc, Hamiyet Donmez-Altunta. A Newly Synthesized Benzimidazolium Salt: 1-(2-Cyanobenzyl)-3-(4-Vinylbenzyl)-1H-Benzo[D]imidazol-3-ium Chloride as a Potential Anticancer Agent for Colon Cancer Treatment, In Vitro Study. Journal of biochemical and molecular toxicology. vol 39. issue 1. 2025-01-03. PMID:39749430. |
our study examined the expressions of some genes related to apoptosis and, additionally, caspase activities with the multicaspase kit. |
2025-01-03 |
2025-01-05 |
Not clear |
| Changchang Liu, Guangyu Duan, Shengjie Xu, Teng Li, Xin Su. Epimedin C alleviated osteoarthritis development by regulating chondrocyte Nrf2-mediated NLRP3 inflammasome axis. Heliyon. vol 10. issue 23. 2024-12-17. PMID:39687146. |
we isolated primary chondrocytes from mice and induced inflammatory damage using interleukin-1β (il-1β) to evaluate epi c's capacity to preserve cell viability and inhibit apoptosis, employing cell counting kit (cck8) assays, edu staining, and flow cytometry. |
2024-12-17 |
2024-12-21 |
mouse |
| Shengliang Cao, Yanlan Li, Lele Chen, Xiaojing Lei, Xiujuan Feng, Yubao L. HSP60 inhibits DF-1 apoptosis through its mitochondrial signal peptide. Poultry science. vol 104. issue 1. 2024-12-05. PMID:39637657. |
first, the crispr-cas9 system was employed to establish the hsp60 knockout df-1 cell line (df-1-hsp60-ko), and the apoptosis level of df-1-hsp60-ko cell line was assessed by flow cytometry and elisa apoptosis kit. |
2024-12-05 |
2024-12-08 |
Not clear |
| Ding Cao, Ekkehard Grünig, Yuriy Sirenko, Ganna Radchenko, Henning Gall, Ayat Ahmed, Susanne Theiß, Mareike Lankeit, Benjamin Meder, Magdalena Laugsch, Christina A Eichstaed. SMAD5 as a novel gene for familial pulmonary arterial hypertension. Clinical science (London, England : 1979). 2024-12-04. PMID:39631055. |
cell viability was evaluated using cell counting kit 8, cell proliferation by brdu and apoptosis by annexin v assay. |
2024-12-04 |
2024-12-07 |
Not clear |
| Xilin Ge, Caoxin Huang, Wenting Chen, Chen Yang, Wenfang Huang, Jia Li, Shuyu Yan. Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells European journal of histochemistry : EJH. vol 68. issue 4. 2024-11-25. PMID:39584968. |
cell viability, apoptosis, and cell proliferation were assessed using the cck-8 kit, annexin v-fitc/propidium iodide apoptosis kit, and edu kit. |
2024-11-25 |
2024-11-27 |
rat |
| Wenyong Zhou, Xin Wang, Bin Yan, Yue Su. Embryonic Lethal Abnormal Visual-Like Protein 1 Aggravates Caerulein-Induced AR42J Cell Injury and Macrophage M1 Polarization to Accelerate Acute Pancreatitis by Upregulating TRAF6. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2024-11-13. PMID:39535226. |
cell viability and apoptosis were measured by cell counting kit 8 assay and flow cytometry. |
2024-11-13 |
2024-11-17 |
Not clear |
| Sheng Liang, Liangliang Zhu, Feng Yang, Haijun Don. Transcription factor YY1-activated GNG5 facilitates glioblastoma cell growth, invasion, stemness and glycolysis through Wnt/β-catenin pathway. Scientific reports. vol 14. issue 1. 2024-10-25. PMID:39448763. |
gbm cell proliferation, apoptosis, invasion and stemness were assessed by cell counting kit 8 assay, edu assay, flow cytometry, transwell assay and sphere formation assay. |
2024-10-25 |
2024-10-28 |
mouse |
| Jie-Qi Zhang, Xiao-Mei Fu, Yue Zhuo, Jin-Na Yang, Ning Hao, Wen-Jia Wang, Yun-Hui Hu, Jian-Song Fan. [Chemical components and in vitro anti-aging activity of Yangxue Qingnao Wan based on UPLC-Q-TOF-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 17. 2024-09-22. PMID:39307805. |
the effects of the compounds on ht22 cell damage and individual cell proliferation ability were observed from overall and individual perspectives by the beyo click~(tm) edu-555 cell proliferation kit, and apoptosis was detected by the annexin v-fitc/pi double staining apoptosis detection kit. |
2024-09-22 |
2024-09-26 |
Not clear |
| Feng-Xia Qu, Xiao Guo, Xiao-Jun Liu, Shu-Wen Zhang, Yue Xin, Jing-Yuan Li, Rong Wang, Chen-Ji Xu, Hai-Ying Li, Chang-Hong L. Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway. Archives of biochemistry and biophysics. 2024-09-13. PMID:39271097. |
changes in reactive oxygen species (ros) levels, mitochondrial membrane potential (ΔΨm), apoptosis and nrf2/ho-1 pathway were analyzed by ros kit, jc-1 kit, tunel assay, western blot and immunohistochemistry. |
2024-09-13 |
2024-09-16 |
rat |
| Chun-Wen Lan, Hsin-Hung Chen, Jim Jinn-Chyuan She. Deoxyelephantopin induces apoptosis and cell cycle arrest in GL261 glioblastoma cells. Naunyn-Schmiedeberg's archives of pharmacology. 2024-09-10. PMID:39254878. |
the effects of det on gbm cell lines were investigated using the mtt assay and annexin-v kit to assess cell death and apoptosis. |
2024-09-10 |
2024-09-13 |
mouse |
| Xue-Hui Shi, Chong-Xi Fan, Quan-Long Yang, Xiao-Ying Wang, Dong-Lin Zhao, Man-Hua Li, Xue-Liang Wu, Jian-Chun Fan, Shou-Bin Nin. [Effect of Pterostilbene Regulating Nuclear Factor E2-Related Factor 2 on Apoptosis of Colon Cancer Cells Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 46. issue 4. 2024-09-02. PMID:39223012. |
methods lovo cells were treated with different concentrations (5,10,20,40,60,80,100 μmol/l) of pterostilbene.cell viability,migration,invasion,and apoptosis were examined by cck-8,scratch,transwell,and tunel assays,respectively.the mitochondrial membrane potential was measured by the mitochondrial membrane potential assay kit with jc-1.the reactive oxygen species level was measured by 2',7'-dichlorofluorescein diacetate.the protein levels of nrf2,phosphorylated nrf2,heme oxygenase 1,and apoptotic proteins (bcl2 and bax) were determined by western blotting.in addition,cell viability,nrf2 expression,and apoptosis rate were determined after co-application of the nrf2-specific agonist sulforaphane. |
2024-09-02 |
2024-09-05 |
human |
| Roaa Mahdi Alreem. Decoding the anti-cancer potential of Pexidartinib (PLX3397), a Fms-like tyrosine kinase 3 inhibitor, using next-generation knowledge discovery methods. Bioinformation. vol 20. issue 5. 2024-08-12. PMID:39132250. |
plx3397 exerts its inhibitory effects by targeting csf1r and kit, leading to the disruption of receptor tyrosine kinase signalling cascades, suppression of leukemic cell growth, and induction of apoptosis. |
2024-08-12 |
2024-08-14 |
Not clear |
| Yinghong He, Yuanmou Li, Yan Zhang, Lixia Chen, Juan Luo, Liqiao Bi, Limei Liu, Xuelian Wang, Meifen L. Transplantation of miR-193b-3p-Transfected BMSCs Improves Neurological Impairment after Traumatic Brain Injury through S1PR3-Mediated Regulation of the PI3K/AKT/mTOR Signaling Pathway. Critical reviews in eukaryotic gene expression. vol 34. issue 7. 2024-07-29. PMID:39072405. |
cell apoptosis was detected by terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick-end labeling (tunel), and cell activity was detected by a cell counting kit 8 (cck-8) assay. |
2024-07-29 |
2024-08-02 |
mouse |
| Wenting Wang, Hongyun Lin, Desheng Liu, Tao Wang, Zicheng Zhu, Peng Yu, Jing Zhan. Ropivacaine synergizes with sorafenib to induce apoptosis of hepatocellular carcinoma cells via the IL-6/STAT3 pathway. Cancer science. 2024-07-16. PMID:39014520. |
the proliferation and apoptosis of hcc cells treated with ropivacaine, sorafenib, and ropivacaine plus sorafenib were analyzed by cell-counting kit 8 and flow cytometry. |
2024-07-16 |
2024-07-19 |
Not clear |
| Ebru Güçlü, İlknur Çınar Ayan, Sümeyra Çetinkaya, Hatice Gül Dursun, Hasibe Vura. Piceatannol induces caspase-dependent apoptosis by modulating intracellular reactive oxygen species/mitochondrial membrane potential and enhances autophagy in neuroblastoma cells. Journal of applied toxicology : JAT. 2024-07-15. PMID:39004823. |
in order to accomplish this goal, we performed various cellular assays, including the xtt cell proliferation assay for cell viability, colony formation assay for colony formation capacity, fitc annexin v and cell death detection kit for apoptosis, matrigel invasion assay for invasion capacity, intracellular reactive oxygen species (ros) red dye for intracellular ros levels, tmrm staining method for mitochondrial membrane potential (mmp), and the cyto-id autophagy detection kit for autophagy. |
2024-07-15 |
2024-07-18 |
human |
| Yanyang Huang, Zhaojing Zhang, Yatian Xu, Yue Peng, Ruochen Xu, Yingying Luan, Xiaoshuai Bie, Jing Jia, Chi Zhang, Tianyi Han, Baixue Zhou, Zhihao Li, Hong Zheng, Dongzhi Yang, Ying H. ARMC10 regulates mitochondrial dynamics and affects mitochondrial function via the Wnt/β-catenin signalling pathway involved in ischaemic stroke. Journal of cellular and molecular medicine. vol 28. issue 12. 2024-06-26. PMID:38924214. |
dcfh-da fluorescent probe was to detect the effect of armc10 on mitochondrial ros level, annexin v-fitc fluorescent probe was to detect the effect of armc10 on apoptosis, and atp assay kit was to detect the effect of armc10 on atp production. |
2024-06-26 |
2024-06-29 |
Not clear |
| Dongwen Liu, Chunyan Song, Cuiling Lv, Aihua Zhan. BONE MARROW MESENCHYMAL STROMAL CELL-DERIVED EXOSOMAL NRF2 AMELIORATES CEREBRAL ISCHEMIA-REPERFUSION INJURY BY TRANSCRIPTIONALLY ACTIVATING LIN28A. Shock (Augusta, Ga.). vol 62. issue 1. 2024-06-20. PMID:38661181. |
tunel cell apoptosis detection kit was used to analyze cell apoptosis in brain tissues. |
2024-06-20 |
2024-06-22 |
mouse |
| Qian Zhang, Dengfeng Che. Validating linalool as a potential drug for breast cancer treatment based on machine learning and molecular docking. Drug development research. vol 85. issue 4. 2024-06-16. PMID:38879780. |
cell counting kit 8 (cck-8, edu, transwell, flow cytometry, and western blot assay were used to analyze cell activity, apoptosis, cell cycle and protein expression. |
2024-06-16 |
2024-06-18 |
human |
| Kitjasit Promsut, Papassara Sangtanoo, Piroonporn Srimongkol, Tanatorn Saisavoey, Songchan Puthong, Anumart Buakeaw, Onrapak Reamtong, Bodee Nutho, Aphichart Karnchanata. A novel peptide derived from Zingiber cassumunar rhizomes exhibits anticancer activity against the colon adenocarcinoma cells (Caco-2) via the induction of intrinsic apoptosis signaling. PloS one. vol 19. issue 6. 2024-06-13. PMID:38870120. |
these peptides were also assessed using the fitc annexin v apoptosis detection kit with pi, confirming the induction of apoptosis. |
2024-06-13 |
2024-06-16 |
human |
| Hui-Ying Jian, Jing-Ting Zhang, Zhuo Liu, Zhen Zhang, Pu-Hua Zen. Amentoflavone reverses epithelial-mesenchymal transition in hepatocellular carcinoma cells by targeting p53 signalling pathway axis. Journal of cellular and molecular medicine. vol 28. issue 11. 2024-06-06. PMID:38842135. |
detection and evaluation of the effects of amentoflavone on cell proliferation, migration, invasion and apoptosis by cck-8 kit, wound healing assay, transwell assay and annexin v-fitc/propidium iodide staining. |
2024-06-06 |
2024-06-08 |
Not clear |