| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoqing Huang, Zhiyong Yang, Yanwen Li, Xingxing Lon. m6A methyltransferase METTL3 facilitates multiple myeloma cell growth through the m6A modification of BZW2. Annals of hematology. 2023-05-24. PMID:37222774. |
cell proliferation and apoptosis were assessed by cell counting kit 8 assay, 5-ethynyl-2'-deoxyuridine assay, colony formation assay, and flow cytometry. |
2023-05-24 |
2023-08-14 |
Not clear |
| Lei Liu, Yu-Hui Sun, Ran An, Rong-Jie Cheng, Nan Li, Jian-Hua Zhen. LDLR promotes autophagy-mediated cisplatin resistance in ovarian cancer associated with the PI3K/AKT/mTOR signaling pathway. The Kaohsiung journal of medical sciences. 2023-05-23. PMID:37218642. |
a cell counting kit 8 assay was employed to evaluate ddp resistance and cell viability, and flow cytometry was used to assess apoptosis. |
2023-05-23 |
2023-08-14 |
Not clear |
| Tayfun Hilmi Akbaba, Yeliz Z Akkaya-Ulum, Ezgi Deniz Batu, Federica Penco, Helmut Wittkowski, Benjamin Kant, Marielle E van Gijn, Dirk Foell, Marco Gattorno, Seza Ozen, Banu Balci-Peynirciogl. Dysregulation of miRNA-30e-3p targeting IL-1β in an international cohort of systemic autoinflammatory disease patients. Journal of molecular medicine (Berlin, Germany). 2023-05-22. PMID:37212859. |
we also performed functional experiments, caspase-1 activation by fluorometric assay kit, apoptosis assay by flow cytometry, and cell migration assays by wound healing and filter system to understand the possible effect of mir-30e-3p on inflammation. |
2023-05-22 |
2023-08-14 |
Not clear |
| Youchao Zeng, Yongsu Xu, Yongjie Pan, Hong Gu. KLF10 knockdown negatively regulates CTRP3 to improve OGD/R-induced brain microvascular endothelial cell injury and barrier dysfunction through Nrf2/HO-1 signaling pathway. Tissue & cell. vol 82. 2023-05-21. PMID:37210762. |
the viability, apoptosis and endothelial permeability of ogd/r-induced hbmecs was detected by cck-8, tunel and fitc-dextran assay kit. |
2023-05-21 |
2023-08-14 |
human |
| Dingwei Yang, Xueyan Yang, Sha Chen, Meiling Lv, Jin Tan, Dingping Yan. Ox-LDL aggravates contrast-induced injury of renal tubular epithelial cells. Journal of biochemical and molecular toxicology. 2023-05-15. PMID:37186061. |
cell viability, apoptosis, mitochondrial membrane potential (mmp) and mitochondrial reactive oxygen species (mtros) were detected by cell counting kit-8, tunel staining, jc-1 kit and mitosox fluorescence, respectively. |
2023-05-15 |
2023-08-14 |
Not clear |
| Q Wang, M Liu, Y Liu, Z Zhang, Z Ba. Cigarette Smoke Extract and Lipopolysaccharide Induce Pyroptosis in Pulmonary Microvascular Endothelial Cells of Rats. Bulletin of experimental biology and medicine. 2023-05-11. PMID:37170021. |
cell viability was determined using the cck8 kit, apoptosis was evaluated by flow cytometry, and cell morphology was evaluated using light microscopy. |
2023-05-11 |
2023-08-14 |
rat |
| Zhe Zhang, Yongzhi Xu, Tingting Zhu, Zhiqin Sang, Xiaoli Guo, Yu Sun, Yuanping Hao, Wanchun Wan. Hypoxia mitigation by manganese-doped carbon dots for synergistic photodynamic therapy of oral squamous cell carcinoma. Frontiers in bioengineering and biotechnology. vol 11. 2023-05-08. PMID:37152644. |
cancer resistance was assessed using the cck-8 kit, calcein am versus propidium iodide (pi) kit, and the annexin v-fitc/pi cell apoptosis assay kit. |
2023-05-08 |
2023-08-14 |
Not clear |
| Joyita Bharati, Nikita Shah, Ankuri Desai, Douglas Gladstone, Chandan Krushna Das, Maria Jacqueline Nieto, Kenar D Jhaveri, Hassan Izzedin. Kidney and urinary tract involvement in systemic mastocytosis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2023-04-28. PMID:37113073. |
systemic mastocytosis (sm) is a disorder of excessive mast cell accumulation in tissues due to a somatic gain-of-function mutation, commonly in the kit gene, which prevents apoptosis of mast cells. |
2023-04-28 |
2023-08-14 |
Not clear |
| Deepak Panwar, Leena Rawal, Sher Al. The potential role of the KFG and KITLG proteins in preventing granulosa cell apoptosis in Bubalus bubalis. Journal, genetic engineering & biotechnology. vol 21. issue 1. 2023-03-31. PMID:37000378. |
these interactions are critical for oocyte development and regulation of follicular atresia which in part are mediated by keratinocyte growth factor (kgf) and kit ligand (kitlg), but their roles in the regulation of apoptosis in buffalo granulosa cells have not yet been defined. |
2023-03-31 |
2023-08-14 |
Not clear |
| Kun Li, Dongbin Zhang, Shuiting Zhai, Huilin Wu, Hongzhi Li. METTL3-METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneurysms. Journal of cell communication and signaling. 2023-03-22. PMID:36947363. |
necroptosis was detected using an annexin v-fitc/pi apoptosis detection kit, and elisa assays measured inflammatory cytokines. |
2023-03-22 |
2023-08-14 |
mouse |
| Xueyan Guo, Yulong Li, Bingbing Wan, Yifei Lv, Xue Wang, Guisheng Liu, Ping Wan. ETV1 inhibition depressed M2 polarization of tumor-associated macrophage and cell process in gastrointestinal stromal tumor via down-regulating PDE3A. Journal of clinical biochemistry and nutrition. vol 72. issue 2. 2023-03-20. PMID:36936869. |
il-4-induced tam promoted etv1 expression, silencing etv1 inhibited proliferation, invasion and kit activation in il-4-treated gist cells, while cell apoptosis was enhanced. |
2023-03-20 |
2023-08-14 |
Not clear |
| Ryugo Teranishi, Tsuyoshi Takahashi, Yuuki Obata, Toshirou Nishida, Shuichi Ohkubo, Hiromi Kazuno, Yurina Saito, Satoshi Serada, Minoru Fujimoto, Yukinori Kurokawa, Takuro Saito, Kazuyoshi Yamamoto, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Seiichi Hirota, Tetsuji Naka, Hidetoshi Eguchi, Yuichiro Dok. Combination of pimitespib (TAS-116) with sunitinib is an effective therapy for imatinib-resistant gastrointestinal stromal tumors. International journal of cancer. 2023-02-08. PMID:36752576. |
in vitro analysis demonstrated that pim and sunitinib combination therapy strongly inhibited growth and induced apoptosis in imatinib-resistant gist cell lines by inhibiting kit signaling and decreasing auto-phosphorylated kit in the golgi apparatus. |
2023-02-08 |
2023-08-14 |
Not clear |
| Jun He, Jian H. Baicalin mitigated IL-1β-Induced osteoarthritis chondrocytes damage through activating mitophagy. Chemical biology & drug design. 2023-02-08. PMID:36752698. |
the effects of different concentrations of baicalin (10, 20 and 40 μm), autophagy inhibitor (3-methyladenine), autophagy activator (rapamycin) and baicalin combined with pi3k agonist (740y-p) on the viability (cell counting kit 8), apoptosis (flow cytometry), autophagy activation (monodansylcadaverine staining) and mitochondrial membrane potential (jc-1 kit) of il-1β induced-chondrocytes were evaluated. |
2023-02-08 |
2023-08-14 |
rat |
| Min Seung Kang, Sangyoon Kim, Da Som Kim, Hak Sun Yu, Ji Eun Le. The amoebicidal effect of Torreya nucifera extract on Acanthamoeba lugdunensis. PloS one. vol 18. issue 2. 2023-02-06. PMID:36745609. |
cell viability was tested using the alamarblue™ method, and the cell death mechanism was confirmed using the tali® apoptosis kit. |
2023-02-06 |
2023-08-14 |
Not clear |
| Xin Zhu, Mei Yang, Liu Yan. Isoflurane Postconditioning Alleviates Ischemic Neuronal Injury via MiR-384-5p Regulated Autophagy. Neuroscience. 2023-01-27. PMID:36707017. |
flow cytometry and cck-8 kit were used to analyze changes in apoptosis and cell viability. |
2023-01-27 |
2023-08-14 |
mouse |
| Yu Dong, Tao Xu, Dongfan Li, Hua Guo, Xusheng Du, Guangshun Li, Jiakuan Chen, Bo Wang, Peng Wang, Gang Yu, Xuan Zhao, Ruiqi Xu. NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer. Bioengineered. vol 13. issue 6. 2023-01-25. PMID:36694434. |
cck-8, annexin-v-fitc/pi apoptosis detection kit, transwell, and wound healing assays were used to determine the cell functions. |
2023-01-25 |
2023-08-14 |
Not clear |
| Izabela Szymczak-Pajor, Józef Drzewoski, Ewa Świderska, Justyna Strycharz, Anna Gabryanczyk, Jacek Kasznicki, Marta Bogdańska, Agnieszka Śliwińsk. Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels). Pharmaceuticals (Basel, Switzerland). vol 16. issue 1. 2023-01-21. PMID:36678613. |
the cells were exposed to metformin, an hat inhibitor (hati), or a combination of an hati with metformin for 24, 48, or 72 h. cell viability was determined using an mtt assay, and the percentage of early apoptotic cells was determined with an annexin v-cy3 apoptosis detection assay kit. |
2023-01-21 |
2023-08-14 |
human |
| Tianxing Ying, Xumeng Wang, Yunjin Yao, Jimeng Yuan, Shitu Chen, Liping Wen, Zhijian Chen, Xiaofeng Wang, Chi Luo, Jinghao Sheng, Weibin Wang, Lisong Ten. Integrative Methylome and Transcriptome Characterization Identifies SERINC2 as a Tumor-Driven Gene for Papillary Thyroid Carcinoma. Cancers. vol 15. issue 1. 2023-01-08. PMID:36612238. |
then, cell counting kit 8 (cck-8), wound healing, and flow cytometric assays were performed to confirm the influence of serinc2 on proliferation and apoptosis in ptc cell lines after intervention or overexpression. |
2023-01-08 |
2023-08-14 |
Not clear |
| Peng Li, Qing-Li Zhao, Mati Ur Rehman, Paras Jawaid, Zheng-Guo Cui, Kanwal Ahmed, Takashi Kondo, Jun-Ichi Saitoh, Kyo Noguch. Isofraxidin enhances hyperthermia‑induced apoptosis via redox modification in acute monocytic leukemia U937 cells. Molecular medicine reports. vol 27. issue 2. 2023-01-05. PMID:36601752. |
apoptosis was measured by annexin v‑fitc/pi double staining assay using flow cytometry and cell viability was observed by cell counting kit assay, dna fragmentation. |
2023-01-05 |
2023-08-14 |
Not clear |
| Jiang Liu, LiJun Ren, HaoWen Wang, Zuowei L. Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells. Biochemical genetics. 2022-12-08. PMID:36480095. |
the effect of isoquercitrin on gc cell lines (ags and hgc-27) was evaluated using cell counting kit-8 assays, colony formation assays, annexin v/pi apoptosis detection kit, western blot analysis, jc-1 staining, immunofluorescence assays, and enzyme-linked immunosorbent assay. |
2022-12-08 |
2023-08-14 |
Not clear |