| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xueyan Guo, Yulong Li, Bingbing Wan, Yifei Lv, Xue Wang, Guisheng Liu, Ping Wan. ETV1 inhibition depressed M2 polarization of tumor-associated macrophage and cell process in gastrointestinal stromal tumor via down-regulating PDE3A. Journal of clinical biochemistry and nutrition. vol 72. issue 2. 2023-03-20. PMID:36936869. |
il-4-induced tam promoted etv1 expression, silencing etv1 inhibited proliferation, invasion and kit activation in il-4-treated gist cells, while cell apoptosis was enhanced. |
2023-03-20 |
2023-08-14 |
Not clear |
| Ryugo Teranishi, Tsuyoshi Takahashi, Yuuki Obata, Toshirou Nishida, Shuichi Ohkubo, Hiromi Kazuno, Yurina Saito, Satoshi Serada, Minoru Fujimoto, Yukinori Kurokawa, Takuro Saito, Kazuyoshi Yamamoto, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Seiichi Hirota, Tetsuji Naka, Hidetoshi Eguchi, Yuichiro Dok. Combination of pimitespib (TAS-116) with sunitinib is an effective therapy for imatinib-resistant gastrointestinal stromal tumors. International journal of cancer. 2023-02-08. PMID:36752576. |
in vitro analysis demonstrated that pim and sunitinib combination therapy strongly inhibited growth and induced apoptosis in imatinib-resistant gist cell lines by inhibiting kit signaling and decreasing auto-phosphorylated kit in the golgi apparatus. |
2023-02-08 |
2023-08-14 |
Not clear |
| Jun He, Jian H. Baicalin mitigated IL-1β-Induced osteoarthritis chondrocytes damage through activating mitophagy. Chemical biology & drug design. 2023-02-08. PMID:36752698. |
the effects of different concentrations of baicalin (10, 20 and 40 μm), autophagy inhibitor (3-methyladenine), autophagy activator (rapamycin) and baicalin combined with pi3k agonist (740y-p) on the viability (cell counting kit 8), apoptosis (flow cytometry), autophagy activation (monodansylcadaverine staining) and mitochondrial membrane potential (jc-1 kit) of il-1β induced-chondrocytes were evaluated. |
2023-02-08 |
2023-08-14 |
rat |
| Min Seung Kang, Sangyoon Kim, Da Som Kim, Hak Sun Yu, Ji Eun Le. The amoebicidal effect of Torreya nucifera extract on Acanthamoeba lugdunensis. PloS one. vol 18. issue 2. 2023-02-06. PMID:36745609. |
cell viability was tested using the alamarblue™ method, and the cell death mechanism was confirmed using the tali® apoptosis kit. |
2023-02-06 |
2023-08-14 |
Not clear |
| Xin Zhu, Mei Yang, Liu Yan. Isoflurane Postconditioning Alleviates Ischemic Neuronal Injury via MiR-384-5p Regulated Autophagy. Neuroscience. 2023-01-27. PMID:36707017. |
flow cytometry and cck-8 kit were used to analyze changes in apoptosis and cell viability. |
2023-01-27 |
2023-08-14 |
mouse |
| Yu Dong, Tao Xu, Dongfan Li, Hua Guo, Xusheng Du, Guangshun Li, Jiakuan Chen, Bo Wang, Peng Wang, Gang Yu, Xuan Zhao, Ruiqi Xu. NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion molecule 1 in non-small cell lung cancer. Bioengineered. vol 13. issue 6. 2023-01-25. PMID:36694434. |
cck-8, annexin-v-fitc/pi apoptosis detection kit, transwell, and wound healing assays were used to determine the cell functions. |
2023-01-25 |
2023-08-14 |
Not clear |
| Izabela Szymczak-Pajor, Józef Drzewoski, Ewa Świderska, Justyna Strycharz, Anna Gabryanczyk, Jacek Kasznicki, Marta Bogdańska, Agnieszka Śliwińsk. Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels). Pharmaceuticals (Basel, Switzerland). vol 16. issue 1. 2023-01-21. PMID:36678613. |
the cells were exposed to metformin, an hat inhibitor (hati), or a combination of an hati with metformin for 24, 48, or 72 h. cell viability was determined using an mtt assay, and the percentage of early apoptotic cells was determined with an annexin v-cy3 apoptosis detection assay kit. |
2023-01-21 |
2023-08-14 |
human |
| Tianxing Ying, Xumeng Wang, Yunjin Yao, Jimeng Yuan, Shitu Chen, Liping Wen, Zhijian Chen, Xiaofeng Wang, Chi Luo, Jinghao Sheng, Weibin Wang, Lisong Ten. Integrative Methylome and Transcriptome Characterization Identifies SERINC2 as a Tumor-Driven Gene for Papillary Thyroid Carcinoma. Cancers. vol 15. issue 1. 2023-01-08. PMID:36612238. |
then, cell counting kit 8 (cck-8), wound healing, and flow cytometric assays were performed to confirm the influence of serinc2 on proliferation and apoptosis in ptc cell lines after intervention or overexpression. |
2023-01-08 |
2023-08-14 |
Not clear |
| Peng Li, Qing-Li Zhao, Mati Ur Rehman, Paras Jawaid, Zheng-Guo Cui, Kanwal Ahmed, Takashi Kondo, Jun-Ichi Saitoh, Kyo Noguch. Isofraxidin enhances hyperthermia‑induced apoptosis via redox modification in acute monocytic leukemia U937 cells. Molecular medicine reports. vol 27. issue 2. 2023-01-05. PMID:36601752. |
apoptosis was measured by annexin v‑fitc/pi double staining assay using flow cytometry and cell viability was observed by cell counting kit assay, dna fragmentation. |
2023-01-05 |
2023-08-14 |
Not clear |
| Jiang Liu, LiJun Ren, HaoWen Wang, Zuowei L. Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells. Biochemical genetics. 2022-12-08. PMID:36480095. |
the effect of isoquercitrin on gc cell lines (ags and hgc-27) was evaluated using cell counting kit-8 assays, colony formation assays, annexin v/pi apoptosis detection kit, western blot analysis, jc-1 staining, immunofluorescence assays, and enzyme-linked immunosorbent assay. |
2022-12-08 |
2023-08-14 |
Not clear |
| Li Zou, ChengHao Xiang, MingFang L. MSI1 Stabilizes MACF1 to Inhibit Apoptosis of MC3T3-E1 Cells Induced by High Glucose and Promote Osteogenic Differentiation Through Wnt/β-Catenin Signaling Pathway. Molecular biotechnology. 2022-11-28. PMID:36443618. |
after transfection, the proliferation, apoptosis, and osteogenic differentiation of hg-induced mc3t3-e1 cells were detected by cell counting kit (cck)-8, terminal deoxynucleotidyl transferase dutp nick end labeling (tunel), alkaline phosphatase (alp) activity assay, and alizarin red staining. |
2022-11-28 |
2023-08-14 |
Not clear |
| Jin Lee, Eun Mi Hong, Jung Han Kim, Jung Hee Kim, Jang Han Jung, Se Woo Park, Dong Hee Ko. Ursodeoxycholic acid inhibits epithelial-mesenchymal transition, suppressing invasiveness of bile duct cancer cells: An Oncology letters. vol 24. issue 6. 2022-11-24. PMID:36420069. |
a cell death elisa kit was used to measure apoptosis, and western blot assays or immunofluorescence staining assays measured the expression levels of various target proteins. |
2022-11-24 |
2023-08-14 |
human |
| Pengran Liu, Dan Zhang, Guixiong Huang, Mingdi Xue, Ying Fang, Lin Lu, Jiayao Zhang, Mao Xie, Zhewei Y. Laminin α1 as a target for the treatment of epidural fibrosis by regulating fibrotic mechanisms. International journal of molecular medicine. vol 51. issue 1. 2022-11-16. PMID:36382649. |
western blot analysis, scratch wound assay, edu incorporation assay, flow cytometric analysis and cell counting kit 8 assay were performed to assess the proliferation, apoptosis, migration and viability of fibroblasts, as well as the expression levels of the akt/mechanistic target of rapamycin (mtor) signaling‑related proteins. |
2022-11-16 |
2023-08-14 |
Not clear |
| Jing-Kun Liu, Abulizi Abudula, Hai-Tao Yang, Li-Xiu Xu, Yiliyaer Nuerrula, Ge Bai, Aisiker Tulahong, Maynur El. DPP3 expression promotes cell proliferation and migration Oncology reports. vol 49. issue 1. 2022-11-16. PMID:36382663. |
the effect of dpp3 expression on cell proliferation, migration or apoptosis was determined in dpp3‑depleted ec cells created by infection with lentivirus containing short hairpin rna specific to the human dpp3 mrna sequence, followed by detection at the cellular level using a celigo cell count assay, flow cytometry, wound‑healing assay and transwell assay as well as chip screening with a human apoptosis antibody array kit, which enables the quantitative detection of 43 apoptosis‑related genes. |
2022-11-16 |
2023-08-14 |
mouse |
| Zhaolin Gao, Min Li, Fei Yao, Xiaobo Xia, Tianqi Duan, Jingzhuo Meng, Yanxia Huang, Ye He, Adonira Saro, Jufang Huan. Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36361772. |
cell apoptosis was determined by a tunel apoptosis detection kit and annexin v-fitc/pi flow cytometry. |
2022-11-11 |
2023-08-14 |
Not clear |
| Xiaxia Xiong, Weiping Xiong, Linyuan Li, Juan DU, Daozhuang Wang, Xu Wan. [Down-regulation of miR-29a inhibits mitochondrial fusion and fission in rat H9c2 cardiomyocytes induced by oxygen and glucose deprivation/reoxygenation]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 11. 2022-11-03. PMID:36328430. |
reverse transcription pcr was used to detect mir-29a interference efficiency, along with cck-8 assay to detect cell proliferation ratio, flow cytometry to detect cell apoptosis rate and mitochondrial membrane potential change, and kit to detect superoxide dismutase(sod), malondialdehyde (mda), lactate dehydrogenase (ldh)contents. |
2022-11-03 |
2023-08-14 |
rat |
| Marta Kunert, Wioletta Rozpedek-Kaminska, Grzegorz Galita, Salvatore Sauro, Rim Bourgi, Louis Hardan, Ireneusz Majsterek, Monika Lukomska-Szymansk. The Cytotoxicity and Genotoxicity of Bioactive Dental Materials. Cells. vol 11. issue 20. 2022-10-27. PMID:36291107. |
additionally, flow cytometry (fc) apoptosis detection was conducted with a fitc (fluorescein isothiocyanate) annexin v apoptosis detection kit i. fc cell-cycle arrest assessment was carried out with propidium iodide staining. |
2022-10-27 |
2023-08-14 |
Not clear |
| Yifan Yang, Jing Xu, Qingxin Su, Yiran Wu, Qizheng Li, Zongren Ma, Tao Din. Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors. Mediators of inflammation. vol 2022. 2022-10-17. PMID:36248188. |
after clinical detection of lpa secretion, spinal cord neurons were treated with lpa (18 : 1); cell viability was analyzed by mtt assay, and ldh leakage was detected by ldh kit; cell apoptosis was detected by flow cytometry; ros production was measured by dcfda staining and mitosox red staining; the activation of the g |
2022-10-17 |
2023-08-14 |
Not clear |
| Proaño-Pérez Elizabeth, Serrano-Candelas Eva, García-Valverde Alfonso, Rosell Jordi, Gómez-Peregrina David, Navinés-Ferrer Arnau, Guerrero Mario, Serrano César, Martín Margarit. The microphthalmia-associated transcription factor is involved in gastrointestinal stromal tumor growth. Cancer gene therapy. 2022-10-14. PMID:36241703. |
mitf silencing decreases cell viability and increases apoptosis in gist cell lines irrespective of the type of kit primary or secondary mutation. |
2022-10-14 |
2023-08-14 |
Not clear |
| Dongxian Zhang, Wanling L. KIF4A knockdown inhibits tumor progression and promotes chemo-sensitivity via induction of P21 in lung cancer cells. Chemical biology & drug design. 2022-10-11. PMID:36217900. |
apoptosis was measured by cell death elisa kit. |
2022-10-11 |
2023-08-14 |
Not clear |