| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abdul Qader Sukkurwala, Sandy Adjemian, Laura Senovilla, Mickaël Michaud, Sabrina Spaggiari, Erika Vacchelli, Elisa Elena Baracco, Lorenzo Galluzzi, Laurence Zitvogel, Oliver Kepp, Guido Kroeme. Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set. Oncoimmunology. vol 3. 2021-02-25. PMID:25050214. |
when initiated by anthracyclines, icd is accompanied by stereotyped molecular changes, including the pre-apoptotic exposure of calreticulin (crt) on the cell surface, the lysosomal secretion of atp during the blebbing phase of apoptosis, and the release of high mobility group box 1 (hmgb1) from dead cells. |
2021-02-25 |
2023-08-13 |
human |
| Guan-Mei Cheng, Ruo-Lu Wang, Bin Zhang, Xiao-Ying Den. The protective effect of uric acid in reducing TLR4/NF-κB activation through the inhibition of HMGB1 acetylation in a model of ischemia-reperfusion injury in vitro. Molecular biology reports. vol 47. issue 4. 2021-02-02. PMID:32095984. |
the results indicated increased cell viability and decreased apoptosis in the presence of hmgb1 sirna and uric acid but the opposite findings in the presence of hmgb1 protein after ogd/r. |
2021-02-02 |
2023-08-13 |
Not clear |
| Patrick Finkel, Benjamin Frey, Friederike Mayer, Karina Bösl, Nina Werthmöller, Andreas Mackensen, Udo S Gaipl, Evelyn Ullric. The dual role of NK cells in antitumor reactions triggered by ionizing radiation in combination with hyperthermia. Oncoimmunology. vol 5. issue 6. 2021-01-12. PMID:27471606. |
in vitro experiments showed that rt plus ht-treated b16 melanoma cells died via apoptosis and necrosis and released especially the danger signal hmgb1. |
2021-01-12 |
2023-08-13 |
Not clear |
| Daniel James Antoine, Dominic P Williams, Anja Kipar, Hugh Laverty, B Kevin Par. Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity. Molecular medicine (Cambridge, Mass.). vol 26. issue 1. 2021-01-12. PMID:32000658. |
expression of concern to: diet restriction inhibits apoptosis and hmgb1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity. |
2021-01-12 |
2023-08-13 |
Not clear |
| Donatella D'Eliseo, Livia Di Renzo, Angela Santoni, Francesca Velott. Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells. Genes & cancer. vol 8. issue 1-2. 2021-01-03. PMID:28435516. |
immunogenic apoptosis was shown by the emission of specific damps (crt, hsp90, hmgb1) by apoptotic mm cells and the activation of their pro-apoptotic autophagy. |
2021-01-03 |
2023-08-13 |
human |
| Yuan Zhang, Yufeng Liu, Xueju X. Upregulation of miR-142-3p Improves Drug Sensitivity of Acute Myelogenous Leukemia through Reducing P-Glycoprotein and Repressing Autophagy by Targeting HMGB1. Translational oncology. vol 10. issue 3. 2021-01-03. PMID:28445844. |
mir-142-3p overexpression improved drug sensitivity of aml cells by inhibiting cell viability and promoting apoptosis, and inhibited p-gp level and autophagy in drug-resistant aml cells, whereas hmgb1 overexpression obviously reversed these effect. |
2021-01-03 |
2023-08-13 |
Not clear |
| Daniel James Antoine, Dominic P Williams, Anja Kipar, Hugh Laverty, B Kevin Par. Retraction Note: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity. Molecular medicine (Cambridge, Mass.). vol 26. issue 1. 2021-01-03. PMID:33380325. |
retraction note: diet restriction inhibits apoptosis and hmgb1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity. |
2021-01-03 |
2023-08-13 |
Not clear |
| Jingxian Xing, Junyan Liu, Juan Liu, Zesheng X. miR-129-5p ameliorates ischemia-reperfusion injury by targeting HMGB1 in myocardium. General physiology and biophysics. vol 39. issue 5. 2020-12-08. PMID:33084599. |
moreover, mir-129-5p overexpression in the cardiomyocytes reduced cell apoptosis and recovered cell viability after a/r injury, which was reversed by subsequent hmgb1 overexpression. |
2020-12-08 |
2023-08-13 |
rat |
| Zhiyong Shu, Xiaogang Miao, Tainhua Tang, Peng Zhan, Langqing Zeng, Yuwen Jian. The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation. International journal of molecular medicine. vol 45. issue 3. 2020-11-30. PMID:31922219. |
to explore the effect of high mobility group box 1 (hmgb1) on chondrocyte apoptosis and catabolism, the atdc5 cell line was cultured as an in vitro model for cartilage research. |
2020-11-30 |
2023-08-13 |
Not clear |
| Zhiyong Shu, Xiaogang Miao, Tainhua Tang, Peng Zhan, Langqing Zeng, Yuwen Jian. The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation. International journal of molecular medicine. vol 45. issue 3. 2020-11-30. PMID:31922219. |
hoechst staining and flow cytometry demonstrated that hmgb1 administration significantly induced apoptosis of atdc5 cells, which was the same as the effect of interleukin‑1β treatment. |
2020-11-30 |
2023-08-13 |
Not clear |
| Zhiyong Shu, Xiaogang Miao, Tainhua Tang, Peng Zhan, Langqing Zeng, Yuwen Jian. The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation. International journal of molecular medicine. vol 45. issue 3. 2020-11-30. PMID:31922219. |
pharmacological inhibitors or hmgb1 knockdown inactivated the gsk‑3β/β‑catenin pathway, inhibited the expression levels of downstream genes, including mmps and adamts, and attenuated the apoptosis of atdc5 cells. |
2020-11-30 |
2023-08-13 |
Not clear |
| Zhiyong Shu, Xiaogang Miao, Tainhua Tang, Peng Zhan, Langqing Zeng, Yuwen Jian. The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation. International journal of molecular medicine. vol 45. issue 3. 2020-11-30. PMID:31922219. |
thus, the findings of the present study demonstrated that hmgb1 induces chondrocyte cell apoptosis via activation of gsk‑3β/β‑catenin and the subsequent expression of multiple targeted genes. |
2020-11-30 |
2023-08-13 |
Not clear |
| Qiong Man, Yi Deng, Pengjie Li, Jun Ma, Zhijun Yang, Xiujuan Yang, Yan Zhou, Xiao Ya. Licorice Ameliorates Cisplatin-Induced Hepatotoxicity Through Antiapoptosis, Antioxidative Stress, Anti-Inflammation, and Acceleration of Metabolism. Frontiers in pharmacology. vol 11. 2020-11-27. PMID:33240085. |
the experimental results indicated that gc can recover functional indices and pathological liver injury, inhibit hepatocyte apoptosis, upregulate b-cell lymphoma/leukemia 2 (bcl-2) and superoxide dismutase (sod) levels, and downregulate cellular tumor antigen p53 (p53), caspase-3, malondialdehyde high mobility group protein b1 (hmgb1), tumor necrosis factor alpha (tnf-α), and interleukin 1β (il-1β) levels. |
2020-11-27 |
2023-08-13 |
Not clear |
| Weitian Li, Qiyu Tang, Na Dai, Weikuan Feng, Changqing Xie, Guofu Cheng, Xiaoli Liu, Wanpo Zhang, Xueying Hu, Changqin G. Receptor-interacting serine/threonine kinase 1- and 3-dependent inflammation induced in lungs of chicken infected with Pasteurella multocida. Scientific reports. vol 10. issue 1. 2020-11-24. PMID:32286320. |
the inflammatory factors hmgb1 and il-6, intercellular matrix mmp, the cell apoptosis-associated caspase-3 and necrotic apoptosis signal molecules ripk1 and ripk3 were widely expressed in the lungs of group q and were significantly different compared with those of 1g1 group and uninfected group (p < 0.05). |
2020-11-24 |
2023-08-13 |
chicken |
| Cui Ying, Liang Ying, Liu Yanxia, Wang Le, Cao Lil. High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model. Acta histochemica. vol 122. issue 2. 2020-11-05. PMID:31870503. |
tdt-mediated dutp nick-end labeling (tunel) illustrated that cell apoptosis induced by seizures in hippocampus was mitigated by hmgb1 antibody. |
2020-11-05 |
2023-08-13 |
mouse |
| Yingjie Wang, Songpo Shen, Zeng Li, Weifeng Li, Xisheng Wen. MIR-140-5p affects chondrocyte proliferation, apoptosis, and inflammation by targeting HMGB1 in osteoarthritis. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. vol 69. issue 1. 2020-10-21. PMID:31712854. |
mir-140-5p affects chondrocyte proliferation, apoptosis, and inflammation by targeting hmgb1 in osteoarthritis. |
2020-10-21 |
2023-08-13 |
Not clear |
| Ishnoor Kaur, Tapan Behl, Simona Bungau, Arun Kumar, Vineet Mehta, Dhruv Setia, Md Sahab Uddin, Gokhan Zengin, Lotfi Aleya, Sandeep Aror. Exploring the therapeutic promise of targeting HMGB1 in rheumatoid arthritis. Life sciences. vol 258. 2020-10-07. PMID:32739467. |
small concentrations of hmgb1 are released during apoptosis, which facilitates oxidative regulation on cys106, and propagates immune inactivating tolerogenic signals in the body. |
2020-10-07 |
2023-08-13 |
Not clear |
| Li-Lun Wang, Yan-Qin Feng, Yu-Hong Chen. Effect on proliferation and apoptosis of retinoblastoma cell by RNA inhibiting high mobility group protein box-1 expression. International journal of ophthalmology. vol 10. issue 1. 2020-10-01. PMID:28149773. |
to investigate the effect of high mobility group protein box-1 (hmgb1) sirna on proliferation and apoptosis of retinoblastoma (rb) cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bin Zhang, Ning Yang, Zhi-Ming Mo, Shao-Peng Lin, Feng Zhan. IL-17A Enhances Microglial Response to OGD by Regulating p53 and PI3K/Akt Pathways with Involvement of ROS/HMGB1. Frontiers in molecular neuroscience. vol 10. 2020-10-01. PMID:28912678. |
these findings demonstrated that ros might be located upstream of il-17a and hmgb1 so that ros can regulate hmgb1/il-17a expression to affect the p53 and pi3k/akt signaling pathways and therefore promote the occurrence of apoptosis in microglial cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yafeng He, Yin Ding, Dan Wang, Wanjun Zhang, Weizhong Chen, Xichun Liu, Weijie Qin, Xiaohong Qian, Hao Chen, Zijian Gu. HMGB1 bound to cisplatin-DNA adducts undergoes extensive acetylation and phosphorylation Chemical science. vol 6. issue 3. 2020-10-01. PMID:29449921. |
hmgb1 bound to cisplatin-dna adducts undergoes extensive acetylation and phosphorylation cisplatin, one of the most effective anticancer drugs, is a dna-damaging agent that induces cell death primarily by apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |