| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong-Ming Zhu, Feng Wu, Jie-Yu Zho. Analysis the effect of miR-141-3p/HMGB1 in LPS-induced mucus production and the apoptosis in nasal epithelial cells. The Kaohsiung journal of medical sciences. vol 36. issue 8. 2021-10-07. PMID:32282121. |
in conclusion, mir-141-3p inhibited lps-induced muac5ac production and the apoptosis of lps-treated necs by targeting hmgb1. |
2021-10-07 |
2023-08-13 |
Not clear |
| Hong-Li Zhu, Yue-Qun Chen, Zhi-Fen Zhan. Downregulation of lncRNA ZFAS1 and upregulation of microRNA-129 repress endocrine disturbance, increase proliferation and inhibit apoptosis of ovarian granulosa cells in polycystic ovarian syndrome by downregulating HMGB1. Genomics. vol 112. issue 5. 2021-10-06. PMID:32320818. |
downregulation of lncrna zfas1 and upregulation of microrna-129 repress endocrine disturbance, increase proliferation and inhibit apoptosis of ovarian granulosa cells in polycystic ovarian syndrome by downregulating hmgb1. |
2021-10-06 |
2023-08-13 |
Not clear |
| Yifei Wu, Yanrui Zhang, Shuxia Zhu, Chunmei Tian, Yanyan Zhan. MiRNA-29a serves as a promising diagnostic biomarker in children with temporal lobe epilepsy and regulates seizure-induced cell death and inflammation in hippocampal neurons. Epileptic disorders : international epilepsy journal with videotape. 2021-10-05. PMID:34609285. |
mir-29a may be involved in the pathogenesis of tle through regulation of neuronal apoptosis and neuroinflammation via targeting hmgb1. |
2021-10-05 |
2023-08-13 |
Not clear |
| Meixuan Liu, Jingjing Lu, Qian Zhang, Yunxuan Zhang, Zhongliang Gu. Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition. Molecular medicine (Cambridge, Mass.). vol 27. issue 1. 2021-10-01. PMID:33541260. |
high mobility group box 1 (hmgb1) is critically required for cellular damage and apoptosis as an important endogenous danger signal. |
2021-10-01 |
2023-08-13 |
Not clear |
| Fan Shi, Dan Luo, Xuexiao Zhou, Qiaozhen Sun, Pei Shen, Shengzhi Wan. Combined effects of hyperthermia and chemotherapy on the regulate autophagy of oral squamous cell carcinoma cells under a hypoxic microenvironment. Cell death discovery. vol 7. issue 1. 2021-09-17. PMID:34465721. |
it is founded that hyperthermia and hypoxia cause autophagy in starvation conditions; further, in hypoxia and innutrition tumor microenvironment, hyperthermia combines yc-1 and 3-ma could inhibit hif-1α/bnip3/beclin1 signal pathway and decrease the secretion of hmgb1; moreover, the cell apoptosis rate increases with an inhibited of cell migration capacity. |
2021-09-17 |
2023-08-13 |
Not clear |
| Rosanne E Frederick, Robert Bearden, Aleksa Jovanovic, Nasreen Jacobson, Rajiv Sood, Sandeep Dhal. Clostridium Collagenase Impact on Zone of Stasis Stabilization and Transition to Healthy Tissue in Burns. International journal of molecular sciences. vol 22. issue 16. 2021-09-15. PMID:34445347. |
additionally, treatment with collagenase reduced necrosis (hmgb1) and apoptosis (cc3a) early in burn injuries, allowing for increased infiltration of cells and protecting tissue from conversion. |
2021-09-15 |
2023-08-13 |
Not clear |
| Xingyao Pei, Haiyang Jiang, Xinyu Liu, Liuan Li, Cun Li, Xilong Xiao, Daowen Li, Shusheng Tan. Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 151. 2021-09-14. PMID:33762183. |
targeting hmgb1 inhibits t-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis. |
2021-09-14 |
2023-08-13 |
Not clear |
| Xingyao Pei, Haiyang Jiang, Xinyu Liu, Liuan Li, Cun Li, Xilong Xiao, Daowen Li, Shusheng Tan. Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 151. 2021-09-14. PMID:33762183. |
conversely, hmgb1 sirna reduced t-2 toxin-mediated oxidative stress, apoptosis and neuroinflammatory outbreak, accompanied by lessened caspase-3 and caspase-9, and decreased secretion of pro-inflammatory cytokines. |
2021-09-14 |
2023-08-13 |
Not clear |
| Xingyao Pei, Haiyang Jiang, Xinyu Liu, Liuan Li, Cun Li, Xilong Xiao, Daowen Li, Shusheng Tan. Targeting HMGB1 inhibits T-2 toxin-induced neurotoxicity via regulation of oxidative stress, neuroinflammation and neuronal apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 151. 2021-09-14. PMID:33762183. |
taken together, t-2 toxin-stimulated pc12 cells simultaneously displayed apoptosis and inflammation, whereas hmgb1 played a critical role in these neurotoxic processes. |
2021-09-14 |
2023-08-13 |
Not clear |
| Wei Xiong, Rui Zhou, Yan Qu, Yuqiao Yang, Zhuoran Wang, Ning Song, Rongbi Liang, Jinqiao Qia. Dexmedetomidine preconditioning mitigates myocardial ischemia/reperfusion injury via inhibition of mast cell degranulation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 141. 2021-09-08. PMID:34237593. |
similarly, compound 48/80 increased levels of cardiac troponin i (ctni) and tryptase, cardiomyocytes apoptosis, and expression of high-mobility group box 1 (hmgb1), toll-like receptor 4 (tlr4), and nuclear factor-kappa b p65 (nf-κb p65) in cardiac tissues induced by i/r injury, but it can be partially decreased by dexmedetomidine pretreatment. |
2021-09-08 |
2023-08-13 |
Not clear |
| Wei Xiong, Rui Zhou, Yan Qu, Yuqiao Yang, Zhuoran Wang, Ning Song, Rongbi Liang, Jinqiao Qia. Dexmedetomidine preconditioning mitigates myocardial ischemia/reperfusion injury via inhibition of mast cell degranulation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 141. 2021-09-08. PMID:34237593. |
our data suggest that dexmedetomidine preconditioning alleviates the degranulation of mast cells and the apoptosis of cardiomyocytes caused by i/r injury, and inhibits the activation of inflammatory related factors hmgb1, tlr4, and nf-κb p65. |
2021-09-08 |
2023-08-13 |
Not clear |
| Fan Lin, Fu Zhen, Xiong Yan, Ye Shaojun, Peng Guizhu, Wang Yanfeng, Ye Qif. Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model. Artificial organs. vol 45. issue 9. 2021-08-16. PMID:33908066. |
graft function after orthotopic liver transplantation was assessed in terms of mitochondrial function (adenosine triphosphate [atp], glycogen), endoplasmic reticulum stress (ppy, grp78, chop, and atf-6), cell apoptosis (tunel assay, caspase-3), inflammatory level (hmgb1, tlr4, il-1β, il-6. |
2021-08-16 |
2023-08-13 |
rat |
| Beilei Liu, Xueqi Gan, Yuwei Zhao, Jing Gao, Haiyang Y. Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions. Journal of physiology and biochemistry. vol 77. issue 2. 2021-08-06. PMID:33635525. |
inhibition of hmgb1 reduced high glucose-induced bmscs apoptosis via activation of ampk and regulation of mitochondrial functions. |
2021-08-06 |
2023-08-13 |
rat |
| Beilei Liu, Xueqi Gan, Yuwei Zhao, Jing Gao, Haiyang Y. Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions. Journal of physiology and biochemistry. vol 77. issue 2. 2021-08-06. PMID:33635525. |
this study aimed to investigate the effect of high glucose on bone marrow stromal cells (bmscs) apoptosis and the role of hmgb1 in this process. |
2021-08-06 |
2023-08-13 |
rat |
| Beilei Liu, Xueqi Gan, Yuwei Zhao, Jing Gao, Haiyang Y. Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions. Journal of physiology and biochemistry. vol 77. issue 2. 2021-08-06. PMID:33635525. |
cell apoptosis, expression of hmgb1, ampk, apoptotic markers, and mitochondrial functions were detected. |
2021-08-06 |
2023-08-13 |
rat |
| Beilei Liu, Xueqi Gan, Yuwei Zhao, Jing Gao, Haiyang Y. Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions. Journal of physiology and biochemistry. vol 77. issue 2. 2021-08-06. PMID:33635525. |
inhibiting hmgb1 by gl improved ampk activation, decreased mitochondrial ros levels, increased mitochondrial membrane potential, normalized mitochondrial fission/fusion balance, and consequently reduced apoptosis of bmscs under hg condition. |
2021-08-06 |
2023-08-13 |
rat |
| Beilei Liu, Xueqi Gan, Yuwei Zhao, Jing Gao, Haiyang Y. Inhibition of HMGB1 reduced high glucose-induced BMSCs apoptosis via activation of AMPK and regulation of mitochondrial functions. Journal of physiology and biochemistry. vol 77. issue 2. 2021-08-06. PMID:33635525. |
taken together, our data show that inhibition of hmgb1 can be an effective approach to alleviate hg-induced bmscs apoptosis by activation of ampk pathway and relieving mitochondrial dysfunction. |
2021-08-06 |
2023-08-13 |
rat |
| Hui Chen, Jinming Liu, Bin Wang, Yongjun L. Protective effect of lncRNA CRNDE on myocardial cell apoptosis in heart failure by regulating HMGB1 cytoplasm translocation through PARP-1. Archives of pharmacal research. vol 43. issue 12. 2021-08-02. PMID:33249529. |
protective effect of lncrna crnde on myocardial cell apoptosis in heart failure by regulating hmgb1 cytoplasm translocation through parp-1. |
2021-08-02 |
2023-08-13 |
mouse |
| Li Liu, Shengchun Liu, Haojun Luo, Chenxi Chen, Xiaoling Zhang, Lin He, Gang T. GPR30-mediated HMGB1 upregulation in CAFs induces autophagy and tamoxifen resistance in ERα-positive breast cancer cells. Aging. vol 13. issue 12. 2021-07-20. PMID:34182538. |
gpr30-induced hmgb1 upregulation triggered mek/erk signaling, leading to increased autophagic behavior to protect cancer cells from tam-induced apoptosis, mimicking the recombinant hmgb1-mediated increase in cancer cell resistance potential to tam. |
2021-07-20 |
2023-08-13 |
Not clear |
| Lan Ling, Lida Zhi, Haifeng Wang, Yihuan Deng, Chengdong G. MicroRNA-181b Inhibits Inflammatory Response and Reduces Myocardial Injury in Sepsis by Downregulating HMGB1. Inflammation. vol 44. issue 4. 2021-07-19. PMID:34076811. |
mir-181b directly targeted hmgb1, and downregulation of hmgb1 reduced inflammatory factors and myocardial injury and inhibited cardiomyocyte apoptosis in sepsis. |
2021-07-19 |
2023-08-13 |
rat |