| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong Pan, Huming Dai, Linzhi Wang, Silong Lin, Yuefeng Tao, Yi Zheng, Renyi Jiang, Fan Fang, Yifan W. MicroRNA-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (HMGB1) in an osteoarthritis mouse model. BMC musculoskeletal disorders. vol 21. issue 1. 2021-05-14. PMID:32709223. |
microrna-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (hmgb1) in an osteoarthritis mouse model. |
2021-05-14 |
2023-08-13 |
mouse |
| Shenquan Guo, Yuanzhi Li, Boyang Wei, Wenchao Liu, Ran Li, Wenping Cheng, Xin Zhang, Xuying He, Xifeng Li, Chuanzhi Dua. Tim-3 deteriorates neuroinflammatory and neurocyte apoptosis after subarachnoid hemorrhage through the Nrf2/HMGB1 signaling pathway in rats. Aging. vol 12. issue 21. 2021-05-13. PMID:33168786. |
tim-3-aav administration aggravated neurocyte apoptosis, brain edema, blood-brain barrier permeability, and neurological dysfunction; significantly inhibited nrf2 expression; and increased hmgb1 expression and secretion of pro-inflammatory cytokines, such as tumor necrosis factor alpha, interleukin (il)-1 beta, il-17, and il-18. |
2021-05-13 |
2023-08-13 |
rat |
| Xing-Jun Cai, Lin-Hui Huang, Yi-Ke Zhu, Yi-Jiang Huan. LncRNA OIP5‑AS1 aggravates house dust mite‑induced inflammatory responses in human bronchial epithelial cells via the miR‑143‑3p/HMGB1 axis. Molecular medicine reports. vol 22. issue 6. 2021-05-13. PMID:33174035. |
mir‑143‑3p overexpression attenuated the der p1‑induced inflammatory response and apoptosis of beas‑2b cells by targeting high mobility group box 1 (hmgb1). |
2021-05-13 |
2023-08-13 |
human |
| Xing-Jun Cai, Lin-Hui Huang, Yi-Ke Zhu, Yi-Jiang Huan. LncRNA OIP5‑AS1 aggravates house dust mite‑induced inflammatory responses in human bronchial epithelial cells via the miR‑143‑3p/HMGB1 axis. Molecular medicine reports. vol 22. issue 6. 2021-05-13. PMID:33174035. |
in summary, oip5‑as1 exacerbated der p1‑induced inflammation and apoptosis in beas‑2b cells by targeting mir‑143‑3p via hmgb1. |
2021-05-13 |
2023-08-13 |
human |
| Yong Meng, Siqiang Qiu, Long Sun, Jinliang Zu. Knockdown of exosome‑mediated lnc‑PVT1 alleviates lipopolysaccharide‑induced osteoarthritis progression by mediating the HMGB1/TLR4/NF‑κB pathway via miR‑93‑5p. Molecular medicine reports. vol 22. issue 6. 2021-05-10. PMID:33174011. |
hmgb1 increase overturned mir‑93‑5p upregulation‑mediated viability, apoptosis, inflammation responses and collagen degradation of lps‑stimulated c28/i2 cells. |
2021-05-10 |
2023-08-13 |
human |
| Yi-Chao Du, Li Lai, Hao Zhang, Fu-Rui Zhong, Huan-Li Cheng, Bao-Lin Qian, Peng Tan, Xian-Ming Xia, Wen-Guang F. Kaempferol from Food & function. vol 11. issue 9. 2021-05-06. PMID:32820776. |
moreover, ka remarkably inhibited high-mobility group box 1 (hmgb1) and toll-like receptor 4 (tlr4) expression as well as nuclear factor kappa-b (nf-κb) activation for liver protection against apap-induced inflammatory responses and apoptosis. |
2021-05-06 |
2023-08-13 |
Not clear |
| Bo Wang, Demin Ji, Wenhua Xing, Feng Li, Zhi Huang, Wenkai Zheng, Jianmin Xue, Yong Zhu, Xuejun Yan. miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells. Cartilage. 2021-05-06. PMID:33955243. |
mir-142-3p and hmgb1 are negatively regulated in proliferation, apoptosis, migration, and autophagy of cartilage endplate cells. |
2021-05-06 |
2023-08-13 |
Not clear |
| Marina Zemskova, Nolan McClain, Maki Niihori, Mathews V Varghese, Joel James, Ruslan Rafikov, Olga Rafikov. Necrosis-Released HMGB1 (High Mobility Group Box 1) in the Progressive Pulmonary Arterial Hypertension Associated With Male Sex. Hypertension (Dallas, Tex. : 1979). vol 76. issue 6. 2021-05-03. PMID:33012199. |
our results showed that hmgb1 is released by either pulmonary artery human endothelial cells or human pulmonary artery smooth muscle cells that underwent necrotic cell death, although only human pulmonary artery smooth muscle cells produce hmgb1 during apoptosis. |
2021-05-03 |
2023-08-13 |
human |
| Efthalia Angelopoulou, Yam Nath Paudel, Christina Piper. Exploring the role of high-mobility group box 1 (HMGB1) protein in the pathogenesis of Huntington's disease. Journal of molecular medicine (Berlin, Germany). vol 98. issue 3. 2021-04-29. PMID:32036391. |
in addition, hmgb1 being a rage and tlr-2, tlr-3, and tlr-4 ligand may further contribute to hd pathogenesis by triggering neuroinflammation and apoptosis. |
2021-04-29 |
2023-08-13 |
Not clear |
| Efthalia Angelopoulou, Yam Nath Paudel, Christina Piper. Exploring the role of high-mobility group box 1 (HMGB1) protein in the pathogenesis of Huntington's disease. Journal of molecular medicine (Berlin, Germany). vol 98. issue 3. 2021-04-29. PMID:32036391. |
furthermore, hmgb1 participates at the unfolded protein response (upr) system and can induce protein degradation and apoptosis associated with hd. |
2021-04-29 |
2023-08-13 |
Not clear |
| Xueke Wang, Xiaoyan Shao, Linaer Gu, Ke Jiang, Sitong Wang, Jianhua Chen, Juemin Fang, Xianling Guo, Min Yuan, Ji Shi, Chan Ding, Songshu Meng, Qing X. Targeting STAT3 enhances NDV-induced immunogenic cell death in prostate cancer cells. Journal of cellular and molecular medicine. vol 24. issue 7. 2021-04-29. PMID:32100392. |
furthermore, pharmacological repression of apoptosis, necroptosis, autophagy or endoplasmic reticulum (er) stress exerted diverse effects on the hmgb1 and hsp70/90 evacuation in ndv/fmw-infected prostate cancer cells. |
2021-04-29 |
2023-08-13 |
mouse |
| C-H Shen, Z-Y Ma, J-H Li, R-D Li, Y-F Tao, Q-B Zhang, Z-X Wan. Glycyrrhizin improves inflammation and apoptosis via suppressing HMGB1 and PI3K/mTOR pathway in lipopolysaccharide-induced acute liver injury. European review for medical and pharmacological sciences. vol 24. issue 12. 2021-04-21. PMID:32633407. |
glycyrrhizin improves inflammation and apoptosis via suppressing hmgb1 and pi3k/mtor pathway in lipopolysaccharide-induced acute liver injury. |
2021-04-21 |
2023-08-13 |
Not clear |
| Ji-Eun Kim, Hana Park, Tae-Hyun Kim, Tae-Cheon Kan. LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus. International journal of molecular sciences. vol 22. issue 5. 2021-04-16. PMID:33668863. |
on the other hand, translocation of high mobility group box 1 (hmgb1) and active caspase-3 into mitochondria is involved in apoptosis of parvalbumin (pv) cells (one of the gabaergic interneurons) and necrosis of ca1 neurons in the rat hippocampus, respectively, following status epilepticus (se). |
2021-04-16 |
2023-08-13 |
rat |
| Yingchun Zhang, Xiaojuan Chu, Qingjie We. MiR-451 Promotes Cell Apoptosis and Inhibits Autophagy in Pediatric Acute Myeloid Leukemia by Targeting HMGB1. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 40. issue 2. 2021-04-08. PMID:33822516. |
mir-451 promotes cell apoptosis and inhibits autophagy in pediatric acute myeloid leukemia by targeting hmgb1. |
2021-04-08 |
2023-08-13 |
Not clear |
| Yingchun Zhang, Xiaojuan Chu, Qingjie We. MiR-451 Promotes Cell Apoptosis and Inhibits Autophagy in Pediatric Acute Myeloid Leukemia by Targeting HMGB1. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 40. issue 2. 2021-04-08. PMID:33822516. |
after cells were co-transfected with pcdna-hmgb1 and pc-dna-ctrl, we investigated apoptosis and autophagy in mir-451 overexpressed cells perturbed by exogenous hmgb1 through mtt, flow cytometry, and western blot. |
2021-04-08 |
2023-08-13 |
Not clear |
| J Feng, J Guo, J-P Wang, B-F Cha. MiR-129-5p inhibits proliferation of gastric cancer cells through targeted inhibition on HMGB1 expression. European review for medical and pharmacological sciences. vol 24. issue 7. 2021-03-29. PMID:32329842. |
the aim of this study was to investigate the effects of micro ribonucleic acid (mir)-129-5p on the proliferation and apoptosis of gastric cancer cells via targeted repression on the expression of high mobility group protein b1 (hmgb1). |
2021-03-29 |
2023-08-13 |
Not clear |
| Shulin Fu, Ronghua Yin, Sanling Zuo, Jun Liu, Yunfei Zhang, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Zhongyuan Wu, Yongqing Hou, Chien-An Andy H. The effects of baicalin on piglets challenged with Glaesserella parasuis. Veterinary research. vol 51. issue 1. 2021-03-25. PMID:32795339. |
our results show that baicalin attenuated the release of the inflammation-related cytokines interleukin (il) 1β, il6, il8, il10, and tumour necrosis factor α (tnf-α) and reduced high mobility group box 1 (hmgb1) production and cell apoptosis in piglets infected with g. parasuis. |
2021-03-25 |
2023-08-13 |
Not clear |
| Shulin Fu, Ronghua Yin, Sanling Zuo, Jun Liu, Yunfei Zhang, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Zhongyuan Wu, Yongqing Hou, Chien-An Andy H. The effects of baicalin on piglets challenged with Glaesserella parasuis. Veterinary research. vol 51. issue 1. 2021-03-25. PMID:32795339. |
taken together, our data suggest that baicalin could protect piglets from g. parasuis by reducing hmgb1 release, attenuating cell apoptosis, and inhibiting mapk signalling activation, thereby alleviating the inflammatory response induced by the bacteria. |
2021-03-25 |
2023-08-13 |
Not clear |
| Li-Xue Wang, Xiao-Mei Zhu, Yi-Nan Luo, Yao Wu, Ning Dong, Ya-Lin Tong, Yong-Ming Ya. Sestrin2 protects dendritic cells against endoplasmic reticulum stress-related apoptosis induced by high mobility group box-1 protein. Cell death & disease. vol 11. issue 2. 2021-03-08. PMID:32071292. |
herein, we firstly reported that sesn2 was expressed in dcs after high mobility group box-1 protein (hmgb1) stimulation and the apoptosis of dcs was obviously increased when sesn2 gene silenced by sirna. |
2021-03-08 |
2023-08-13 |
Not clear |
| Xiang Zhao, Ari Rouhiainen, Zhilin Li, Su Guo, Heikki Rauval. Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. vol 9. issue 7. 2021-03-04. PMID:32708917. |
enhanced apoptosis is also found in the neuronal cells lacking hmgb1. |
2021-03-04 |
2023-08-13 |
mouse |