| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chi Zhang, Weizhong Yu, Chongbo Huang, Qinghe Ding, Chizhang Liang, Le Wang, Zhiqi Hou, Zhiyong Zhan. Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression. Molecular medicine reports. vol 19. issue 2. 2019-05-28. PMID:30535473. |
these results demonstrated that hmgb‑1 is critical for the protective effect of ch on human osteoarthritis chondrocytes, including cell apoptosis and inflammatory factor inhibition, which suggests that ch may have potential therapeutic effect in treating oa by protecting human osteoarthritis chondrocytes via hmgb1 suppression. |
2019-05-28 |
2023-08-13 |
human |
| Antonella Santillo, Lucia Figliola, Mariangela Caroprese, Rosaria Marino, Maria dʼApolito, Ida Giardino, Marzia Albenzi. Effect of lipid fraction of digested milk from different sources in mature 3T3-L1 adipocyte. The Journal of dairy research. vol 86. issue 1. 2019-04-15. PMID:30729901. |
cellular viability, apoptosis, oxidative response and gene expression levels of nf-κb p65, hmgb1, srebp-1c and fas were evaluated. |
2019-04-15 |
2023-08-13 |
human |
| Zinah Zwaini, Houyong Dai, Cordula Stover, Bin Yan. Role of Complement Properdin in Renal Ischemia-Reperfusion Injury. Current gene therapy. vol 17. issue 6. 2019-04-12. PMID:29446739. |
the multiple actions of properdin associated with hmgb1 and caspase-3, apoptosis and inflammation mediators, are discussed in the context of immunity, injury and repair at both the early and later stages of aki. |
2019-04-12 |
2023-08-13 |
Not clear |
| Yichao Jin, Zhen Guan, Xiaochuan Wang, Zhiqiong Wang, Rong Zeng, Liangheng Xu, Ping Ca. ALA-PDT promotes HPV-positive cervical cancer cells apoptosis and DCs maturation via miR-34a regulated HMGB1 exosomes secretion. Photodiagnosis and photodynamic therapy. vol 24. 2019-04-09. PMID:30118903. |
ala-pdt promotes hpv-positive cervical cancer cells apoptosis and dcs maturation via mir-34a regulated hmgb1 exosomes secretion. |
2019-04-09 |
2023-08-13 |
mouse |
| Yichao Jin, Zhen Guan, Xiaochuan Wang, Zhiqiong Wang, Rong Zeng, Liangheng Xu, Ping Ca. ALA-PDT promotes HPV-positive cervical cancer cells apoptosis and DCs maturation via miR-34a regulated HMGB1 exosomes secretion. Photodiagnosis and photodynamic therapy. vol 24. 2019-04-09. PMID:30118903. |
hence we concluded that ala-pdt treatment specifically inhibited hpv-positive cervical cancer cells' proliferative ability, promoted cell apoptosis and modulated dcs maturation by regulating mir-34a mediated hmgb1 exosomes secretion. |
2019-04-09 |
2023-08-13 |
mouse |
| Salah Alduais, Yaser Alduais, Xiaolei Wu, Haosen Li, Jing Ma. HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells. BioFactors (Oxford, England). vol 44. issue 6. 2019-03-20. PMID:30375073. |
high mobility group box 1 protein (hmgb1) is functionally dynamic and pleiotropic molecule, it has the potential to promote both cell survival and death by regulating multiple signaling pathways, including inflammation and apoptosis. |
2019-03-20 |
2023-08-13 |
Not clear |
| Salah Alduais, Yaser Alduais, Xiaolei Wu, Haosen Li, Jing Ma. HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells. BioFactors (Oxford, England). vol 44. issue 6. 2019-03-20. PMID:30375073. |
this study aimed at investigating the role of silencing hmgb1 on tumor cells apoptosis and pro-inflammatory proteins expression in hepatocellular hepg2 cancer cells. |
2019-03-20 |
2023-08-13 |
Not clear |
| Shirong Cao, Shu Li, Yating Wang, Jiani Shen, Yi Zhou, Huiyan Li, Xueqing Yu, Haiping Ma. Acetylation of HMGB1 by JNK1 Signaling Promotes LPS-Induced Peritoneal Mesothelial Cells Apoptosis. BioMed research international. vol 2018. 2019-03-18. PMID:30539006. |
acetylation of hmgb1 by jnk1 signaling promotes lps-induced peritoneal mesothelial cells apoptosis. |
2019-03-18 |
2023-08-13 |
mouse |
| Shirong Cao, Shu Li, Yating Wang, Jiani Shen, Yi Zhou, Huiyan Li, Xueqing Yu, Haiping Ma. Acetylation of HMGB1 by JNK1 Signaling Promotes LPS-Induced Peritoneal Mesothelial Cells Apoptosis. BioMed research international. vol 2018. 2019-03-18. PMID:30539006. |
overexpression of wild-type, but not hypoacetylation mutant of hmgb1, enhanced lps-induced apoptosis in hmrsv5 cells, which was accompanied by elevated protein levels of bax and cleaved-caspase 3 compared to the control. |
2019-03-18 |
2023-08-13 |
mouse |
| Qiong Shi, Yawen Wang, Wenjing Dong, Erqun Song, Yang Son. Polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by HMGB1 and p53 in human hepatoma HepG2 cells. Toxicology letters. vol 306. 2019-03-18. PMID:30742880. |
polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by hmgb1 and p53 in human hepatoma hepg2 cells. |
2019-03-18 |
2023-08-13 |
human |
| Qiong Shi, Yawen Wang, Wenjing Dong, Erqun Song, Yang Son. Polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by HMGB1 and p53 in human hepatoma HepG2 cells. Toxicology letters. vol 306. 2019-03-18. PMID:30742880. |
hmgb1 and p53 both serve as transcription factors that play crucial roles in the regulation of pcb29-pq-induced autophagy and apoptosis. |
2019-03-18 |
2023-08-13 |
human |
| Qiong Shi, Yawen Wang, Wenjing Dong, Erqun Song, Yang Son. Polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by HMGB1 and p53 in human hepatoma HepG2 cells. Toxicology letters. vol 306. 2019-03-18. PMID:30742880. |
interestingly, hmgb1 rather than p53 plays a primary role in 5 μm of pcb29-pq-induced autophagy in the nucleus; however, p53 promoted apoptosis to a great extent in the cytosol at the dose of 15 μm pcb29-pq. |
2019-03-18 |
2023-08-13 |
human |
| Qiong Shi, Yawen Wang, Wenjing Dong, Erqun Song, Yang Son. Polychlorinated biphenyl quinone-induced signaling transition from autophagy to apoptosis is regulated by HMGB1 and p53 in human hepatoma HepG2 cells. Toxicology letters. vol 306. 2019-03-18. PMID:30742880. |
together, hmgb1 and p53 provided a subtle balance between autophagy and apoptosis, thus determining the fate of pcb29-pq-treated cells. |
2019-03-18 |
2023-08-13 |
human |
| Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zo. Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression. Oncology reports. vol 41. issue 3. 2019-03-11. PMID:30569171. |
high mobility group box 1 (hmgb1) plays a crucial part in inhibiting the apoptosis of cancer cells after irradiation treatment. |
2019-03-11 |
2023-08-13 |
human |
| Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zo. Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression. Oncology reports. vol 41. issue 3. 2019-03-11. PMID:30569171. |
the influence of hmgb1 on radiation‑induced changes in the migration, invasion, and cell cycle as well as apoptosis of tumor cells was examined by wound‑healing and transwell assays and flow cytometry, respectively. |
2019-03-11 |
2023-08-13 |
human |
| Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zo. Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression. Oncology reports. vol 41. issue 3. 2019-03-11. PMID:30569171. |
moreover, hmgb1 was involved in the phosphorylation of h2ax after irradiation, and hmgb1 knockdown blocked the cell cycle in the g0/g1 phase and increased apoptosis. |
2019-03-11 |
2023-08-13 |
human |
| Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zo. Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression. Oncology reports. vol 41. issue 3. 2019-03-11. PMID:30569171. |
these data indicated that the overexpression of hmgb1 prior to treatment was correlated with poor clinical outcome in esophageal carcinoma and that knockdown hmgb1 expression in human esophageal cancer cell lines increased their radiosensitivity by allowing the induction of apoptosis and g0/g1 arrest after exposure to radiation. |
2019-03-11 |
2023-08-13 |
human |
| M Li, Y Li, L Sun, J L Song, C L. [High mobility group box 1 promotes apoptosis of astrocytes after oxygen glucose deprivation/reoxygenation by regulating the expression of Bcl-2 and Bax]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. vol 50. issue 5. 2019-03-05. PMID:30337736. |
to investigate the effect of high mobility group protein box 1 (hmgb1) on apoptosis of astrocytes after oxygen glucose deprivation/reoxygenation (ogd/r), and to investigate the possible mechanism by evaluating the expression of apoptosis related protein bcl-2 and bax. |
2019-03-05 |
2023-08-13 |
Not clear |
| Angela Raucci, Stefania Di Maggio, Francesco Scavello, Alessandro D'Ambrosio, Marco E Bianchi, Maurizio C Capogross. The Janus face of HMGB1 in heart disease: a necessary update. Cellular and molecular life sciences : CMLS. vol 76. issue 2. 2019-01-30. PMID:30306212. |
hmgb1 decreases contractility and induces hypertrophy and apoptosis in cardiomyocytes, stimulates cardiac fibroblast activities, and promotes cardiac stem cell proliferation and differentiation. |
2019-01-30 |
2023-08-13 |
mouse |
| Angela Raucci, Stefania Di Maggio, Francesco Scavello, Alessandro D'Ambrosio, Marco E Bianchi, Maurizio C Capogross. The Janus face of HMGB1 in heart disease: a necessary update. Cellular and molecular life sciences : CMLS. vol 76. issue 2. 2019-01-30. PMID:30306212. |
interestingly, maintenance of appropriate nuclear hmgb1 levels protects cardiomyocytes from apoptosis by preventing dna oxidative stress, and mice with hmgb1cardiomyocyte-specific overexpression are partially protected from cardiac damage. |
2019-01-30 |
2023-08-13 |
mouse |