| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anlin Feng, Zhenbo Tu, Bingjiao Yi. The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer. Oncotarget. vol 7. issue 15. 2018-01-24. PMID:26840258. |
therefore, we focused on how hmgb1 affected the prognosis and development of adc using bioinformatics analyses and detected that the mitogen-activated protein kinases (mapk), apoptosis and cell cycle signaling pathways were the key pathways that varied during hmgb1 up-regulation in adc. |
2018-01-24 |
2023-08-13 |
Not clear |
| Efthalia Angelopoulou, Christina Piperi, Christos Adamopoulos, Athanasios G Papavassilio. Pivotal role of high-mobility group box 1 (HMGB1) signaling pathways in glioma development and progression. Journal of molecular medicine (Berlin, Germany). vol 94. issue 8. 2018-01-16. PMID:27262996. |
upon receptor binding, hmgb1 triggers the activation of key signaling pathways and immune responses, involved in the regulation of cell growth, differentiation, motility, and apoptosis. |
2018-01-16 |
2023-08-13 |
human |
| Jing-Hua Wu, Jia-Pei Guo, Jun Shi, Hui Wang, Lei-Lei Li, Bin Guo, Dian-Xing Liu, Qing Cao, Zhi-Yong Yua. CMA down-regulates p53 expression through degradation of HMGB1 protein to inhibit irradiation-triggered apoptosis in hepatocellular carcinoma. World journal of gastroenterology. vol 23. issue 13. 2018-01-02. PMID:28428710. |
cma down-regulates p53 expression through degradation of hmgb1 protein to inhibit irradiation-triggered apoptosis in hepatocellular carcinoma. |
2018-01-02 |
2023-08-13 |
Not clear |
| Da Gao, Ai-E Lv, Hui-Ping Li, Dong-Hai Han, Ya-Peng Zhan. LncRNA MALAT-1 Elevates HMGB1 to Promote Autophagy Resulting in Inhibition of Tumor Cell Apoptosis in Multiple Myeloma. Journal of cellular biochemistry. vol 118. issue 10. 2017-12-21. PMID:28295550. |
lncrna malat-1 elevates hmgb1 to promote autophagy resulting in inhibition of tumor cell apoptosis in multiple myeloma. |
2017-12-21 |
2023-08-13 |
mouse |
| Da Gao, Ai-E Lv, Hui-Ping Li, Dong-Hai Han, Ya-Peng Zhan. LncRNA MALAT-1 Elevates HMGB1 to Promote Autophagy Resulting in Inhibition of Tumor Cell Apoptosis in Multiple Myeloma. Journal of cellular biochemistry. vol 118. issue 10. 2017-12-21. PMID:28295550. |
lncrna malat-1 increases the expression level of hmgb1 in mm thereby promotes autophagy resulting in the inhibition of apoptosis. |
2017-12-21 |
2023-08-13 |
mouse |
| Qun Huang, Zhen Yang, Ji-Peng Zhou, Ying Lu. HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28251435. |
hmgb1 induces endothelial progenitor cells apoptosis via rage-dependent perk/eif2α pathway. |
2017-12-04 |
2023-08-13 |
Not clear |
| Qun Huang, Zhen Yang, Ji-Peng Zhou, Ying Lu. HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28251435. |
studies have demonstrated that the high-mobility group 1b protein (hmgb1) could regulate endothelial progenitor cell (epc) homing, but the effect of hmgb1 on epc apoptosis and associated mechanisms are still unclear. |
2017-12-04 |
2023-08-13 |
Not clear |
| Qun Huang, Zhen Yang, Ji-Peng Zhou, Ying Lu. HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28251435. |
the aim of this study was to investigate the effects of hmgb1 on epc apoptosis and the possible involvement of the endoplasmic reticulum (er) stress pathway. |
2017-12-04 |
2023-08-13 |
Not clear |
| Qun Huang, Zhen Yang, Ji-Peng Zhou, Ying Lu. HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28251435. |
our results showed that incubation of epcs with hmgb1 (0.1-1 μg/ml) for 12-48 h induced apoptosis as well as activated er stress transducers, as assessed by up-regulating perk protein expression and eif2α phosphorylation in a dose or time-dependent manner. |
2017-12-04 |
2023-08-13 |
Not clear |
| Qun Huang, Zhen Yang, Ji-Peng Zhou, Ying Lu. HMGB1 induces endothelial progenitor cells apoptosis via RAGE-dependent PERK/eIF2α pathway. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28251435. |
our novel findings suggest that hmgb1 triggered epc apoptosis in a manner of rage-mediated activation of the perk/eif2α pathway. |
2017-12-04 |
2023-08-13 |
Not clear |
| Wenbo Zhang, Aibin Tao, Ting Lan, Gediminas Cepinskas, Raymond Kao, Claudio M Martin, Tao Ru. Carbon monoxide releasing molecule-3 improves myocardial function in mice with sepsis by inhibiting NLRP3 inflammasome activation in cardiac fibroblasts. Basic research in cardiology. vol 112. issue 2. 2017-09-26. PMID:28168403. |
challenging cm with supernatants of cf with lps/atp or cyto-mix (il-1β, il-18, and hmgb1) resulted in cm apoptosis, which was attenuated with either a corm-3 or il-1 receptor antagonist. |
2017-09-26 |
2023-08-13 |
mouse |
| Kishu Ranjan, Chandramani Patha. Expression of cFLIPL Determines the Basal Interaction of Bcl-2 With Beclin-1 and Regulates p53 Dependent Ubiquitination of Beclin-1 During Autophagic Stress. Journal of cellular biochemistry. vol 117. issue 8. 2017-09-15. PMID:26682748. |
the apoptosis associated proteins such as bcl-2 and p53 have a close association with autophagic proteins hmgb1 and beclin-1 to modulate autophagic signaling. |
2017-09-15 |
2023-08-13 |
Not clear |
| Samer Tohme, Hamza O Yazdani, Yao Liu, Patricia Loughran, Dirk J van der Windt, Hai Huang, Richard L Simmons, Sruti Shiva, Sheng Tai, Allan Tsun. Hypoxia mediates mitochondrial biogenesis in hepatocellular carcinoma to promote tumor growth through HMGB1 and TLR9 interaction. Hepatology (Baltimore, Md.). vol 66. issue 1. 2017-09-13. PMID:28370295. |
without hmgb1, hypoxic hcc cells had significantly reduced adenosine triphosphate production, decreased cellular proliferation, and increased apoptosis. |
2017-09-13 |
2023-08-13 |
human |
| Alireza Jian Bagherpoor, Dasa Dolezalova, Tomas Barta, Martin Kučírek, Soodabeh Abbasi Sani, Milan Ešner, Michaela Kunova Bosakova, Vladimír Vinarský, Lucie Peskova, Aleš Hampl, Michal Štro. Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins. Stem cells and development. vol 26. issue 5. 2017-09-11. PMID:27863459. |
hmgb1 and hmgb2 proteins have been implicated in numerous cellular processes, including proliferation, differentiation, apoptosis, and tumor growth. |
2017-09-11 |
2023-08-13 |
human |
| Alireza Jian Bagherpoor, Dasa Dolezalova, Tomas Barta, Martin Kučírek, Soodabeh Abbasi Sani, Milan Ešner, Michaela Kunova Bosakova, Vladimír Vinarský, Lucie Peskova, Aleš Hampl, Michal Štro. Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins. Stem cells and development. vol 26. issue 5. 2017-09-11. PMID:27863459. |
using inducible, stably transfected hescs capable of shrna-mediated knockdown of hmgb1 and hmgb2, we provide evidence that downregulation of hmgb1 and/or hmgb2 in undifferentiated hescs does not affect the stemness of cells and induces only minor changes to the proliferation rate, cell-cycle profile, and apoptosis. |
2017-09-11 |
2023-08-13 |
human |
| Guillermo Mazzolini, Jan-Peter Sowa, Ali Canba. Cell death mechanisms in human chronic liver diseases: a far cry from clinical applicability. Clinical science (London, England : 1979). vol 130. issue 23. 2017-08-24. PMID:27798227. |
moreover, current methods applicable in patients are limited to surrogate markers for apoptosis (m30), and possibly for pyroptosis (il-1 family) and necro(pto)sis (hmgb1). |
2017-08-24 |
2023-08-13 |
human |
| Cíntia Yuki Fukuoka, Alyne Simões, Toshikazu Uchiyama, Victor Elias Arana-Chavez, Yoshimitsu Abiko, Noboru Kuboyama, Ujjal K Bhawa. The Effects of Low-Power Laser Irradiation on Inflammation and Apoptosis in Submandibular Glands of Diabetes-Induced Rats. PloS one. vol 12. issue 1. 2017-08-16. PMID:28099448. |
taken together, our data suggest that lpli reduces diabetes-induced inflammation by reducing the induction of hmgb1, ultimately leading to inhibition of apoptosis in submandibular glands of diabetic rats. |
2017-08-16 |
2023-08-13 |
rat |
| Xiao-Ling Zhu, Xin Chen, Wei Wang, Xu Li, Jia Huo, Yu Wang, Yu-Yuan Min, Bin-Xiao Su, Jian-Ming Pe. Electroacupuncture pretreatment attenuates spinal cord ischemia-reperfusion injury via inhibition of high-mobility group box 1 production in a LXA Brain research. vol 1659. 2017-08-07. PMID:28089662. |
the ea-pretreated animals displayed better motor performance after reperfusion along with the decrease of apoptosis, hmgb1, tnf-α and il-1β expressions in the spinal cord, whereas these effects by ea pretreatment was reversed by rhmgb1 administration. |
2017-08-07 |
2023-08-13 |
Not clear |
| Hairuo Lin, Liang Shen, Xiajun Zhang, Jiahe Xie, Huixin Hao, Yingxue Zhang, Zhenhuan Chen, Hiroshi Yamamoto, Wangjun Liao, Jianping Bin, Shiping Cao, Xiaobo Huang, Yulin Lia. HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload. PloS one. vol 11. issue 6. 2017-07-19. PMID:27355349. |
considering that inflammation is involved in pressure overload-induced cardiac hypertrophy, we herein attempted to investigate whether hmgb1 plays a role in myocardial hypertrophy in rage knockout mice as well as in the growth and apoptosis of cardiomyocytes. |
2017-07-19 |
2023-08-13 |
mouse |
| Hairuo Lin, Liang Shen, Xiajun Zhang, Jiahe Xie, Huixin Hao, Yingxue Zhang, Zhenhuan Chen, Hiroshi Yamamoto, Wangjun Liao, Jianping Bin, Shiping Cao, Xiaobo Huang, Yulin Lia. HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload. PloS one. vol 11. issue 6. 2017-07-19. PMID:27355349. |
cultured neonatal rat cardiomyocytes were treated with different concentrations of recombinant hmgb1, then cell viability was determined using mtt and cck8 assays and cell apoptosis was determined by hoechst staining and tunel assay. |
2017-07-19 |
2023-08-13 |
mouse |