| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hairuo Lin, Liang Shen, Xiajun Zhang, Jiahe Xie, Huixin Hao, Yingxue Zhang, Zhenhuan Chen, Hiroshi Yamamoto, Wangjun Liao, Jianping Bin, Shiping Cao, Xiaobo Huang, Yulin Lia. HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload. PloS one. vol 11. issue 6. 2017-07-19. PMID:27355349. |
the results came out that hmgb1 exerted no influence on viability or apoptosis of cardiomyocytes. |
2017-07-19 |
2023-08-13 |
mouse |
| Hairuo Lin, Liang Shen, Xiajun Zhang, Jiahe Xie, Huixin Hao, Yingxue Zhang, Zhenhuan Chen, Hiroshi Yamamoto, Wangjun Liao, Jianping Bin, Shiping Cao, Xiaobo Huang, Yulin Lia. HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload. PloS one. vol 11. issue 6. 2017-07-19. PMID:27355349. |
these findings indicate that hmgb1 neither exerts influence on cardiac remodeling by binding to rage nor induces apoptosis of cardiomyocytes under physiological condition. |
2017-07-19 |
2023-08-13 |
mouse |
| Liru Liu, Weihua Ren, Kuisheng Che. MiR-34a Promotes Apoptosis and Inhibits Autophagy by Targeting HMGB1 in Acute Myeloid Leukemia Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 41. issue 5. 2017-06-23. PMID:28478444. |
mir-34a promotes apoptosis and inhibits autophagy by targeting hmgb1 in acute myeloid leukemia cells. |
2017-06-23 |
2023-08-13 |
Not clear |
| D S Pisetsk. Mechanisms of Chromatin Remodeling and Repurposing During Extracellular Translocation. Advances in protein chemistry and structural biology. vol 106. 2017-06-20. PMID:28057209. |
thus, during apoptosis, dna can be cleaved, histones can be posttranslationally modified and a nuclear protein called hmgb1 (high mobility group box 1) can undergo redox changes. |
2017-06-20 |
2023-08-13 |
human |
| Ke Liu, Jun Huang, Jiangdong Ni, Deye Song, Muliang Ding, Junjie Wang, Xianzhe Huang, Wenzhao L. MALAT1 promotes osteosarcoma development by regulation of HMGB1 via miR-142-3p and miR-129-5p. Cell cycle (Georgetown, Tex.). vol 16. issue 6. 2017-06-19. PMID:28346809. |
moreover, knockdown of malat1 decreased hmgb1 expression, inhibited os cell growth and promoted apoptosis, while mir-142-3p and mir-129-5p inhibitor partly restored the inhibitory effect of malat1 knockdown on hmgb1 expression, os cell growth and the promotion of apoptosis. |
2017-06-19 |
2023-08-13 |
human |
| Ye Bai, Shaohui Du, Fei Li, Fengyuan Huang, Rudong Deng, Jianhong Zhou, Dongfeng Che. Histone deacetylase-high mobility group box-1 pathway targeted by hypaconitine suppresses the apoptosis of endothelial cells. Experimental biology and medicine (Maywood, N.J.). vol 242. issue 5. 2017-06-14. PMID:28056545. |
the effect of hypaconitine on the oxldl-induced apoptosis and hmgb1 release in endothelial cells was significantly reduced by the suppression of hdac3 by sirna or a specific inhibitor. |
2017-06-14 |
2023-08-13 |
Not clear |
| C Pan, Y Wang, M K Qiu, S Q Wang, Y B Liu, Z W Quan, J M O. Knockdown of HMGB1 inhibits cell proliferation and induces apoptosis in hemangioma via downregulation of AKT pathway. Journal of biological regulators and homeostatic agents. vol 31. issue 1. 2017-06-01. PMID:28337869. |
knockdown of hmgb1 inhibits cell proliferation and induces apoptosis in hemangioma via downregulation of akt pathway. |
2017-06-01 |
2023-08-13 |
human |
| C Pan, Y Wang, M K Qiu, S Q Wang, Y B Liu, Z W Quan, J M O. Knockdown of HMGB1 inhibits cell proliferation and induces apoptosis in hemangioma via downregulation of AKT pathway. Journal of biological regulators and homeostatic agents. vol 31. issue 1. 2017-06-01. PMID:28337869. |
the high mobility group box 1 (hmgb1) as a conserved non-histone nuclear protein has been involved in a variety of biological processes of cancer, such as cell proliferation, apoptosis, angiogenesis and metastasis. |
2017-06-01 |
2023-08-13 |
human |
| C Pan, Y Wang, M K Qiu, S Q Wang, Y B Liu, Z W Quan, J M O. Knockdown of HMGB1 inhibits cell proliferation and induces apoptosis in hemangioma via downregulation of AKT pathway. Journal of biological regulators and homeostatic agents. vol 31. issue 1. 2017-06-01. PMID:28337869. |
cell function experiments, including mtt, cell colony formation and flow cytometry analysis were performed to evaluate the effects of hmgb1 knockdown on cell proliferation and apoptosis in ha crl-2586 eoma cells. |
2017-06-01 |
2023-08-13 |
human |
| C Pan, Y Wang, M K Qiu, S Q Wang, Y B Liu, Z W Quan, J M O. Knockdown of HMGB1 inhibits cell proliferation and induces apoptosis in hemangioma via downregulation of AKT pathway. Journal of biological regulators and homeostatic agents. vol 31. issue 1. 2017-06-01. PMID:28337869. |
moreover, knockdown of hmgb1 gene in vitro suppressed eoma cell proliferation and colony formation and induced cell apoptosis and cycle arrest at g0/g1 phase by downregulation of pcna, cyclind1, p-akt and upregulation of p53 and cleaved parp. |
2017-06-01 |
2023-08-13 |
human |
| Sebastian Vogel, Dominik Rath, Oliver Borst, Andreas Mack, Patricia Loughran, Michael T Lotze, Matthew D Neal, Timothy R Billiar, Meinrad Gawa. Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes. Biochemical and biophysical research communications. vol 478. issue 1. 2017-05-23. PMID:27449608. |
in transgenic mice with platelet-specific ablation of hmgb1 and neutralization studies, we show that hmgb1 derived from platelets promotes recruitment of monocytes and prevents monocytes from undergoing apoptosis. |
2017-05-23 |
2023-08-13 |
mouse |
| Sebastian Vogel, Dominik Rath, Oliver Borst, Andreas Mack, Patricia Loughran, Michael T Lotze, Matthew D Neal, Timothy R Billiar, Meinrad Gawa. Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes. Biochemical and biophysical research communications. vol 478. issue 1. 2017-05-23. PMID:27449608. |
platelet-derived hmgb1 mediated monocyte migration via the receptor for advanced glycation end products (rage) and suppressed apoptosis via toll-like receptor 4 (tlr4)-dependent activation of mapk/erk (extracellular signal-regulated kinase) in monocytes. |
2017-05-23 |
2023-08-13 |
mouse |
| Sebastian Vogel, Dominik Rath, Oliver Borst, Andreas Mack, Patricia Loughran, Michael T Lotze, Matthew D Neal, Timothy R Billiar, Meinrad Gawa. Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes. Biochemical and biophysical research communications. vol 478. issue 1. 2017-05-23. PMID:27449608. |
in conclusion, we identify platelet-derived hmgb1 as a critical regulator of monocyte recruitment and apoptosis, with potential implications in disease states associated with thrombosis and inflammation. |
2017-05-23 |
2023-08-13 |
mouse |
| Feifei Wang, Jiajing Yin, Yujin Ma, Hongwei Jiang, Yanbo L. Vitexin alleviates lipopolysaccharide‑induced islet cell injury by inhibiting HMGB1 release. Molecular medicine reports. vol 15. issue 3. 2017-05-09. PMID:28098903. |
in conclusion, the results indicated that vitexin prevented lps‑induced islet tissue damage in rats, and ins‑1 cells injury and apoptosis by inhibiting hmgb1 release. |
2017-05-09 |
2023-08-13 |
rat |
| Eleonora Foglio, Giovanni Puddighinu, Antonia Germani, Matteo A Russo, Federica Liman. HMGB1 Inhibits Apoptosis Following MI and Induces Autophagy via mTORC1 Inhibition. Journal of cellular physiology. vol 232. issue 5. 2017-05-08. PMID:27580416. |
hmgb1 inhibits apoptosis following mi and induces autophagy via mtorc1 inhibition. |
2017-05-08 |
2023-08-13 |
mouse |
| Eleonora Foglio, Giovanni Puddighinu, Antonia Germani, Matteo A Russo, Federica Liman. HMGB1 Inhibits Apoptosis Following MI and Induces Autophagy via mTORC1 Inhibition. Journal of cellular physiology. vol 232. issue 5. 2017-05-08. PMID:27580416. |
we report the first in vivo evidence that hmgb1 treatment in a murine model of acute mi might induce cardiomyocyte survival through attenuation of apoptosis and amp-activated protein kinase-dependent autophagy. |
2017-05-08 |
2023-08-13 |
mouse |
| b' Agnieszka Irena Mazur-Bialy, Ewa Poche\\xc4\\x8. Riboflavin Reduces Pro-Inflammatory Activation of Adipocyte-Macrophage Co-culture. Potential Application of Vitamin B2 Enrichment for Attenuation of Insulin Resistance and Metabolic Syndrome Development. Molecules (Basel, Switzerland). vol 21. issue 12. 2017-04-28. PMID:27983705.' |
the apoptosis of adipocytes and macrophages as well as tumor necrosis factor-alpha (tnf-α), interleukin 6 (il-6), interleukin 1beta (il-1β), monocyte chemotactic protein 1 (mcp-1), high-mobility group box 1 (hmgb1), transforming growth factor-beta 1 (tgfβ), interleukin 10 (il-10), inducible nitric oxide synthase (inos), nitric oxide (no), matrix metalloproteinase 9 (mmp-9), tissue inhibitor of metalloproteinases-1 (timp-1) expression and release, macrophage migration and adipokines (adiponectin and leptin) were determined. |
2017-04-28 |
2023-08-13 |
Not clear |
| Zhiwei Wang, Xiaoyan Wang, Jiantian Li, Cheng Yang, Zhiyuan Xing, Ruiyun Chen, Fei X. HMGB1 knockdown effectively inhibits the progression of rectal cancer by suppressing HMGB1 expression and promoting apoptosis of rectal cancer cells. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27220399. |
hmgb1 knockdown effectively inhibits the progression of rectal cancer by suppressing hmgb1 expression and promoting apoptosis of rectal cancer cells. |
2017-04-06 |
2023-08-13 |
human |
| Zhiwei Wang, Xiaoyan Wang, Jiantian Li, Cheng Yang, Zhiyuan Xing, Ruiyun Chen, Fei X. HMGB1 knockdown effectively inhibits the progression of rectal cancer by suppressing HMGB1 expression and promoting apoptosis of rectal cancer cells. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27220399. |
these data indicated that hmgb1 may act as an oncogene in rectal cancer, and knockdown of endogenous hmgb1 expression may significantly inhibit the proliferation of colorectal cancer cells and promote apoptosis of tumor cells. |
2017-04-06 |
2023-08-13 |
human |
| Xiuqin Wang, Yanqing Guo, Chunyan Wang, Hong Yu, Xiuxiang Yu, Hongbo Y. MicroRNA-142-3p Inhibits Chondrocyte Apoptosis and Inflammation in Osteoarthritis by Targeting HMGB1. Inflammation. vol 39. issue 5. 2017-03-30. PMID:27447821. |
microrna-142-3p inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting hmgb1. |
2017-03-30 |
2023-08-13 |
mouse |