| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arnau Panisello-Roselló, Eva Verde, Alexandre Lopez, Marta Flores, Emma Folch-Puy, Anabela Rolo, Carlos Palmeira, Georgina Hotter, Teresa Carbonell, René Adam, Joan Roselló-Catafa. Cytoprotective Mechanisms in Fatty Liver Preservation against Cold Ischemia Injury: A Comparison between IGL-1 and HTK. International journal of molecular sciences. vol 19. issue 2. 2018-08-01. PMID:29364854. |
this was concomitant with significant increased cyto-protective autophagy and prevention of liver apoptosis, including inflammatory cytokines such as hmgb1. |
2018-08-01 |
2023-08-13 |
rat |
| Wenbo Lei, Qun Li, Shengmei Su, Jichang Bu, Qiulin Huang, Zhongyu L. Chlamydia trachomatis plasmid-encoded protein pORF5 protects mitochondrial function by inducing mitophagy and increasing HMGB1 expression. Pathogens and disease. vol 75. issue 9. 2018-07-23. PMID:29040500. |
knockdown high mobility group box 1 (hmgb1) by lentivirus suppressed porf5-induced mitophagy and increased apoptosis, implying that porf5 may participate in cell death signalling pathways via up-regulation of hmgb1. |
2018-07-23 |
2023-08-13 |
Not clear |
| Wenbo Lei, Qun Li, Shengmei Su, Jichang Bu, Qiulin Huang, Zhongyu L. Chlamydia trachomatis plasmid-encoded protein pORF5 protects mitochondrial function by inducing mitophagy and increasing HMGB1 expression. Pathogens and disease. vol 75. issue 9. 2018-07-23. PMID:29040500. |
thus, we concluded that up-regulation of hmgb1 is a pivotal event for c. trachomatis that manipulates mitophagy and apoptosis in order to establish a favourable environment supportive of chlamydial growth, which should further promote our understanding of chlamydial pathogenic mechanisms. |
2018-07-23 |
2023-08-13 |
Not clear |
| Li-Hong Wang, Min-Huan Wu, Po-Chun Chen, Chen-Ming Su, Guohong Xu, Chien-Chung Huang, Chun-Hao Tsai, Yuan-Li Huang, Chih-Hsin Tan. Prognostic significance of high-mobility group box protein 1 genetic polymorphisms in rheumatoid arthritis disease outcome. International journal of medical sciences. vol 14. issue 13. 2018-07-20. PMID:29200952. |
high-mobility group box protein 1 (hmgb1) is a ubiquitous nuclear protein found in all mammal eukaryotic cells that participates in several biological functions including immune response, cell survival and apoptosis. |
2018-07-20 |
2023-08-13 |
Not clear |
| Yingcheng Zheng, Guoguo Zh. HMGB1 suppresses colon carcinoma cell apoptosis triggered by co‑culture with dendritic cells via an ER stress‑associated autophagy pathway. Molecular medicine reports. vol 17. issue 2. 2018-07-20. PMID:29257231. |
hmgb1 suppresses colon carcinoma cell apoptosis triggered by co‑culture with dendritic cells via an er stress‑associated autophagy pathway. |
2018-07-20 |
2023-08-13 |
mouse |
| Yingcheng Zheng, Guoguo Zh. HMGB1 suppresses colon carcinoma cell apoptosis triggered by co‑culture with dendritic cells via an ER stress‑associated autophagy pathway. Molecular medicine reports. vol 17. issue 2. 2018-07-20. PMID:29257231. |
furthermore, hmgb1 promoted er stress‑induced autophagy through the activation of jnk, which inhibited the apoptosis triggered by the dendritic cells, suggesting that hmgb1 has a role in immune evasion by colon cancer cells. |
2018-07-20 |
2023-08-13 |
mouse |
| Daniel Hao Lin, Arijit Biswas, Mahesh Choolani, Chui-Yee Fong, Ariff Bongs. Induction of Immunogenic Cell Death in Lymphoma Cells by Wharton's Jelly Mesenchymal Stem Cell Conditioned Medium. Stem cell reviews and reports. vol 13. issue 6. 2018-07-18. PMID:28918474. |
thereafter, lymphoma cells were exposed to 500 µg/ml of the hwjsc-cm-3 kda concentrate and then subjected to analysis for morphology, viability, apoptosis, mitochondrial and endoplasmic reticulum stress, danger associated molecular patterns (damp), extracellular hmgb1, cd47 and pd-l1 markers and dendritic cell phenotype. |
2018-07-18 |
2023-08-13 |
human |
| Dong Han, Xiang Li, Shuang Li, Tao Su, Li Fan, Wen-Si Fan, Hong-Yu Qiao, Jiang-Wei Chen, Miao-Miao Fan, Xiu-Juan Li, Ya-Bin Wang, Sai Ma, Ya Qiu, Zu-Hong Tian, Feng Ca. Reduced silent information regulator 1 signaling exacerbates sepsis-induced myocardial injury and mitigates the protective effect of a liver X receptor agonist. Free radical biology & medicine. vol 113. 2018-07-05. PMID:28993270. |
furthermore, the levels of myocardial inflammatory cytokines (tnf-α, il-6, il-1β, mcp-1, mpo and hmgb1), oxidative stress (ros generation, mda), endoplasmic-reticulum (er) stress (protein levels of chop, grp78, grp94, ire1α, and atf6), and cardiac apoptosis following clp were inhibited by t0901317 treatment in wild-type mice but not in sirt1-/- mice. |
2018-07-05 |
2023-08-13 |
mouse |
| Chengcheng Ieong, Haogen Sun, Qiangping Wang, Junpeng M. Glycyrrhizin suppresses the expressions of HMGB1 and ameliorates inflammative effect after acute subarachnoid hemorrhage in rat model. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 47. 2018-06-22. PMID:29078973. |
we found the use of glycyrrhizin significantly improved neurological scores, reduced hmgb1-positive cells, down-regulated mrna and protein levels of hmgb1, inhibited bbb permeability, and attenuated neuronal cell death and apoptosis after sah. |
2018-06-22 |
2023-08-13 |
rat |
| Weiwei Hu, Po-Yi Liu, Yi-Chen Yang, Po-Chun Chen, Chen-Ming Su, Chia-Chia Chao, Chih-Hsin Tan. Association of International journal of medical sciences. vol 14. issue 12. 2018-06-21. PMID:29104475. |
high-mobility group box 1 protein (hmgb1) is a ubiquitous nuclear protein found in eukaryotic cells that participates in several biological functions including immune response, cell survival, apoptosis and cancer development. |
2018-06-21 |
2023-08-13 |
Not clear |
| Wei Chen, Jie Lian, Jing-Jing Ye, Qing-Fei Mo, Jie Qin, Guang-Liang Hong, Long-Wang Chen, Shao-Ce Zhi, Guang-Ju Zhao, Zhong-Qiu L. Ethyl pyruvate reverses development of Pseudomonas aeruginosa pneumonia during sepsis-induced immunosuppression. International immunopharmacology. vol 52. 2018-06-12. PMID:28863323. |
then cytokines including lung il-6, il-1β, il-10 and plasma hmgb1, apoptosis of splenic immune cells and foxp3 level on regulatory t cells (tregs) were studied to demonstrate the mechanisms of ep administration on two-hit mice. |
2018-06-12 |
2023-08-13 |
mouse |
| Wei Chen, Jie Lian, Jing-Jing Ye, Qing-Fei Mo, Jie Qin, Guang-Liang Hong, Long-Wang Chen, Shao-Ce Zhi, Guang-Ju Zhao, Zhong-Qiu L. Ethyl pyruvate reverses development of Pseudomonas aeruginosa pneumonia during sepsis-induced immunosuppression. International immunopharmacology. vol 52. 2018-06-12. PMID:28863323. |
we found that the susceptibility of septic mice to secondary pseudomonas aeruginosa pneumonia could be down-regulated by ethyl pyruvate treatment and the protective effects of ep may via decreasing lung il-10 and plasma hmgb1 expression, inhibiting the function of tregs and relieving the apoptosis of splenic immune cells. |
2018-06-12 |
2023-08-13 |
mouse |
| Richard Nuccitelli, Amanda McDaniel, Snjezana Anand, John Cha, Zachary Mallon, Jon Casey Berridge, Darrin Uecke. Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death. Journal for immunotherapy of cancer. vol 5. 2018-06-08. PMID:28428881. |
here we present evidence that nps stimulates both caspase 3/7 activation indicative of apoptosis, as well as the emission of three critical damps: ecto-calreticulin (crt), atp and hmgb1. |
2018-06-08 |
2023-08-13 |
Not clear |
| Yongsong Cai, Peng Xu, Le Yang, Ke Xu, Jialin Zhu, Xiaoqing Wu, Congshan Jiang, Qiling Yuan, Bo Wang, Yuanbo Li, Yusheng Qi. HMGB1-mediated autophagy decreases sensitivity to oxymatrine in SW982 human synovial sarcoma cells. Scientific reports. vol 6. 2018-06-01. PMID:27897164. |
when hmgb1 was inhibited via hmgb1-sirna, omt-induced autophagy was decreased, and apoptosis was increased. |
2018-06-01 |
2023-08-13 |
human |
| Anja Petrović, Desanka Bogojević, Aleksandra Korać, Igor Golić, Sofija Jovanović-Stojanov, Vesna Martinović, Svetlana Ivanović-Matić, Jelena Stevanović, Goran Poznanović, Ilijana Grigoro. Oxidative stress-dependent contribution of HMGB1 to the interplay between apoptosis and autophagy in diabetic rat liver. Journal of physiology and biochemistry. vol 73. issue 4. 2018-05-02. PMID:28695466. |
oxidative stress-dependent contribution of hmgb1 to the interplay between apoptosis and autophagy in diabetic rat liver. |
2018-05-02 |
2023-08-13 |
rat |
| Anja Petrović, Desanka Bogojević, Aleksandra Korać, Igor Golić, Sofija Jovanović-Stojanov, Vesna Martinović, Svetlana Ivanović-Matić, Jelena Stevanović, Goran Poznanović, Ilijana Grigoro. Oxidative stress-dependent contribution of HMGB1 to the interplay between apoptosis and autophagy in diabetic rat liver. Journal of physiology and biochemistry. vol 73. issue 4. 2018-05-02. PMID:28695466. |
since reduced hmgb1 binds to rage but not to tlr4, redox modification of hmgb1 as a mechanism regulating the cross-talk between apoptosis and autophagy in diabetes is discussed. |
2018-05-02 |
2023-08-13 |
rat |
| Kan Torii, Akimichi Morit. UVB irradiation induces HMGB1 expression in keratinocytes without promoting apoptosis. Experimental dermatology. vol 25. issue 9. 2018-02-26. PMID:27094746. |
uvb irradiation induces hmgb1 expression in keratinocytes without promoting apoptosis. |
2018-02-26 |
2023-08-13 |
Not clear |
| Biao Xie, Ke Cao, Jinjin Li, Jia Chen, Jintian Tang, Xiang Chen, Kun Xia, Xiao Zhou, Yan Cheng, Jianda Zhou, Huiqing Xi. Hmgb1 inhibits Klotho expression and malignant phenotype in melanoma cells by activating NF-κB. Oncotarget. vol 7. issue 49. 2018-02-22. PMID:27779100. |
in this study, knockdown of hmgb1 expression increased apoptosis, reduced invasion and p-nf-κb expression, but increased klotho protein level in melanoma tumor cells. |
2018-02-22 |
2023-08-13 |
Not clear |
| Biao Xie, Ke Cao, Jinjin Li, Jia Chen, Jintian Tang, Xiang Chen, Kun Xia, Xiao Zhou, Yan Cheng, Jianda Zhou, Huiqing Xi. Hmgb1 inhibits Klotho expression and malignant phenotype in melanoma cells by activating NF-κB. Oncotarget. vol 7. issue 49. 2018-02-22. PMID:27779100. |
introduction of exogenous hmgb1 significantly decreased apoptosis, increased invasion, elevated p-nf-κb, but lowered klotho protein level in melanoma cells. |
2018-02-22 |
2023-08-13 |
Not clear |
| Daqiong Jiang, Huiyan Wang, Zhuyan Li, Zhen Li, Xin Chen, Hongbing Ca. MiR-142 inhibits the development of cervical cancer by targeting HMGB1. Oncotarget. vol 8. issue 3. 2018-02-16. PMID:27829233. |
in conclusion, the present work suggested that mir-142 affects cervical cancer cell proliferation and invasiveness, and enhances cell apoptosis via directly targeting the expression of hmgb1, and these findings may lay a novel foundation for the promising therapy target of cervical cancer. |
2018-02-16 |
2023-08-13 |
human |