| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fuxing Lin, Jie Yang, Umair Muhammad, Jing Sun, Zhenghua Huang, Wei Li, Fengxia Lv, Zhaoxin L. Bacillomycin D-C16 triggers apoptosis of gastric cancer cells through the PI3K/Akt and FoxO3a signaling pathways. Anti-cancer drugs. vol 30. issue 1. 2020-06-02. PMID:30169424. |
together, these findings indicated that bacillomycin d-c16 induces apoptosis through the pi3k/akt and foxo3a signaling pathways. |
2020-06-02 |
2023-08-13 |
Not clear |
| Gabriela Nestal De Moraes, Carolina Pereira Castro, Eduardo Jesus Salustiano, Matheus Lourenço Dumas, Fernanda Costas, Eric Wing-Fai Lam, Paulo Roberto Ribeiro Costa, Raquel Ciuvalschi Mai. [Corrigendum] The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors. International journal of oncology. vol 55. issue 6. 2020-04-02. PMID:31545420. |
[corrigendum] the pterocarpanquinone lqb-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets foxo3a and foxm1 transcription factors. |
2020-04-02 |
2023-08-13 |
Not clear |
| Yonghan Peng, Cheng Yang, Xiaolei Shi, Ling Li, Hao Dong, Changcheng Liu, Ziyu Fang, Zeyu Wang, Shaoxiong Ming, Min Liu, Bin Xie, Xiaofeng Gao, Yinghao Su. Sirt3 suppresses calcium oxalate-induced renal tubular epithelial cell injury via modification of FoxO3a-mediated autophagy. Cell death & disease. vol 10. issue 2. 2020-03-30. PMID:30674870. |
foxo3a was found to interact with the promoter region of lc3b and to increase its expression, enhancing tec autophagy and suppressing cell apoptosis and necrosis. |
2020-03-30 |
2023-08-13 |
mouse |
| Jing Long, Cheng-Shun Yang, Jun-Lin He, Xue-Qing Liu, Yu-Bin Ding, Xue-Mei Chen, Chao Tong, Chuan Peng, Ying-Xiong Wang, Ru-Fei Ga. FOXO3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy. Journal of cellular physiology. vol 234. issue 4. 2020-03-16. PMID:30132880. |
foxo3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy. |
2020-03-16 |
2023-08-13 |
mouse |
| Jing Long, Cheng-Shun Yang, Jun-Lin He, Xue-Qing Liu, Yu-Bin Ding, Xue-Mei Chen, Chao Tong, Chuan Peng, Ying-Xiong Wang, Ru-Fei Ga. FOXO3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy. Journal of cellular physiology. vol 234. issue 4. 2020-03-16. PMID:30132880. |
in primary stromal cells, apoptosis was reduced by decreased expression of foxo3a after inducing decidualization. |
2020-03-16 |
2023-08-13 |
mouse |
| Jing Long, Cheng-Shun Yang, Jun-Lin He, Xue-Qing Liu, Yu-Bin Ding, Xue-Mei Chen, Chao Tong, Chuan Peng, Ying-Xiong Wang, Ru-Fei Ga. FOXO3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy. Journal of cellular physiology. vol 234. issue 4. 2020-03-16. PMID:30132880. |
thus, foxo3a might play an important role in decidualization during early pregnancy, and cell apoptosis might be one of pathways for foxo3a-regulated decidualization. |
2020-03-16 |
2023-08-13 |
mouse |
| Pei Wu, Chuanjin Ding, Meijuan Yan, Biying Qian, Wei Wang, Pingping Sun, Jianmei Zha. Perfluorooctane sulfonate induces apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins in PC12 cells. The Journal of toxicological sciences. vol 44. issue 10. 2020-02-06. PMID:31588057. |
perfluorooctane sulfonate induces apoptosis via activation of foxo3a and upregulation of proapoptotic bcl-2 proteins in pc12 cells. |
2020-02-06 |
2023-08-13 |
Not clear |
| Pei Wu, Chuanjin Ding, Meijuan Yan, Biying Qian, Wei Wang, Pingping Sun, Jianmei Zha. Perfluorooctane sulfonate induces apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins in PC12 cells. The Journal of toxicological sciences. vol 44. issue 10. 2020-02-06. PMID:31588057. |
in addition, knockdown of foxo3a gene inhibited bim expression and apoptosis. |
2020-02-06 |
2023-08-13 |
Not clear |
| Shuang Wang, Ning Wang, Bin Yu, Mingxing Cao, Yanlong Wang, Yuqi Guo, Yanli Zhang, Ping Zhang, Xiao Yu, Shujing Wang, Li Zeng, Bin Liang, Xin Li, Yingjie W. Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model. Oncogene. vol 38. issue 36. 2020-01-28. PMID:31312023. |
igf-1 elevation led to the accumulation of foxo3a in the cytosol of prostate tumor cells and downregulation of its target gene bim, which resulted in the apoptosis inhibition and prostate cancer overgrowth. |
2020-01-28 |
2023-08-13 |
mouse |
| Shuang Feng, Zhi-Jia Jiang, Dong Yu, Jun Li, Geng Liu, Jin-Jin Su. FOXO3a expression and its diagnostic value in pancreatic ductal adenocarcinoma. International journal of clinical and experimental pathology. vol 11. issue 11. 2020-01-21. PMID:31949625. |
foxo3a (fkhrl1) is an important regulator of cell apoptosis, proliferation, metabolic state and longevity. |
2020-01-21 |
2023-08-13 |
Not clear |
| Haichao Chen, Liqi Xu, Lei Wan. Expression of miR-182 and Foxo3a in patients with bladder cancer correlate with prognosis. International journal of clinical and experimental pathology. vol 12. issue 11. 2020-01-17. PMID:31933819. |
the expression of mir-182 and foxo3a in bladder cancer tissues and their relationship with the prognosis of the patients were analyzed, and the role of mir-182 in regulating the expression of foxo3a and the biologic process of cell proliferation and apoptosis in bladder cancer cells was explored. |
2020-01-17 |
2023-08-13 |
Not clear |
| Weiwei Kong, Chuang Li, Qiaofang Qi, Jiahui Shen, Kaiwen Chan. Cardamonin induces G2/M arrest and apoptosis via activation of the JNK-FOXO3a pathway in breast cancer cells. Cell biology international. 2020-01-08. PMID:31393045. |
the addition of nac markedly reversed these effects, knockdown of foxo3a using small interfering rna also decreased cd-induced g2/m arrest and apoptosis. |
2020-01-08 |
2023-08-13 |
Not clear |
| Zhenxing Liu, Zhichen Shi, Jieru Lin, Shuang Zhao, Min Hao, Junting Xu, Yuyin Li, Qing Zhao, Li Tao, Aipo Dia. Piperlongumine-induced nuclear translocation of the FOXO3A transcription factor triggers BIM-mediated apoptosis in cancer cells. Biochemical pharmacology. vol 163. 2019-12-18. PMID:30753811. |
piperlongumine-induced nuclear translocation of the foxo3a transcription factor triggers bim-mediated apoptosis in cancer cells. |
2019-12-18 |
2023-08-13 |
Not clear |
| Zhenxing Liu, Zhichen Shi, Jieru Lin, Shuang Zhao, Min Hao, Junting Xu, Yuyin Li, Qing Zhao, Li Tao, Aipo Dia. Piperlongumine-induced nuclear translocation of the FOXO3A transcription factor triggers BIM-mediated apoptosis in cancer cells. Biochemical pharmacology. vol 163. 2019-12-18. PMID:30753811. |
the transcription factor forkhead box o 3a (foxo3a) is a tumor suppressor that promotes cell cycle arrest and apoptosis. |
2019-12-18 |
2023-08-13 |
Not clear |
| Xianfang Rong, Jun Rao, Dan Li, Qinghe Jing, Yi Lu, Yinghong J. TRIM69 inhibits cataractogenesis by negatively regulating p53. Redox biology. vol 22. 2019-11-25. PMID:30844644. |
furthermore, inhibition of ros mitigated the effects of uvb irradiation on ros production, cell apoptosis, forkhead box protein 3a (foxo3a) phosphorylation, and trim69 expression. |
2019-11-25 |
2023-08-13 |
human |
| Shenwei Zhang, Yilin Zhao, Ming Xu, Li Yu, Yujie Zhao, Jianghong Chen, Yiqiang Yuan, Qiangsun Zheng, Xiaolin Ni. Correction: FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells. PloS one. vol 8. issue 12. 2019-11-20. PMID:29161729. |
correction: foxo3a modulates hypoxia stress induced oxidative stress and apoptosis in cardiac microvascular endothelial cells. |
2019-11-20 |
2023-08-13 |
Not clear |
| Suzan Demir Pektas, Gursoy Dogan, Tuba Gokdogan Edgunlu, Sevim Karakas-Celik, Esra Ermis, Nilgun Solak Teki. The Role of Forkhead Box Class O3A and SIRT1 Gene Variants in Early-Onset Psoriasis. Indian journal of dermatology. vol 63. issue 3. 2019-11-20. PMID:29937556. |
forkhead box class o3a (foxo3a) is a transcription factor, which plays an important role in cell-cycle regulation, apoptosis, oxidative stress, and dna repair. |
2019-11-20 |
2023-08-13 |
Not clear |
| Li Sun, Yuan Huang, Yeying Liu, Yujie Zhao, Xiaoxiao He, Lingling Zhang, Feng Wang, Yingjie Zhan. Ipatasertib, a novel Akt inhibitor, induces transcription factor FoxO3a and NF-κB directly regulates PUMA-dependent apoptosis. Cell death & disease. vol 9. issue 9. 2019-11-15. PMID:30185800. |
ipatasertib, a novel akt inhibitor, induces transcription factor foxo3a and nf-κb directly regulates puma-dependent apoptosis. |
2019-11-15 |
2023-08-13 |
Not clear |
| Li Sun, Yuan Huang, Yeying Liu, Yujie Zhao, Xiaoxiao He, Lingling Zhang, Feng Wang, Yingjie Zhan. Ipatasertib, a novel Akt inhibitor, induces transcription factor FoxO3a and NF-κB directly regulates PUMA-dependent apoptosis. Cell death & disease. vol 9. issue 9. 2019-11-15. PMID:30185800. |
ipatasertib led to p53-independent puma activation by inhibiting akt, thereby activating both foxo3a and nf-κb synchronously that will directly bind to puma promoter, up-regulating puma transcription and bax-mediated intrinsic mitochondrial apoptosis. |
2019-11-15 |
2023-08-13 |
Not clear |
| P-P Wang, Y-J Zhang, T Xie, J Sun, X-D Wan. MiR-223 promotes cardiomyocyte apoptosis by inhibiting Foxo3a expression. European review for medical and pharmacological sciences. vol 22. issue 18. 2019-11-14. PMID:30280799. |
mir-223 promotes cardiomyocyte apoptosis by inhibiting foxo3a expression. |
2019-11-14 |
2023-08-13 |
Not clear |