| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guangyi Qin, Ping Li, Zhuowei Xu. Triptolide induces protective autophagy and apoptosis in human cervical cancer cells by downregulating Akt/mTOR activation. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30128010. |
these results suggested that triptolide induces protective autophagy, suppresses cell viability and promotes apoptosis in human cervical cancer cells by inducing the autophagy-targeting phosphoinositide 3-kinase/akt/mtor, p38, mapk, p53 and foxo3a pathways. |
2020-09-30 |
2023-08-13 |
human |
| Dongjie Liu, Renbing Yuan, Fang Yang, Dehui Zhan. Effects of tanshinones mediated by forkhead box O3a transcription factor on the proliferation and apoptosis of lung cancer cells. Oncology letters. vol 17. issue 1. 2020-09-30. PMID:30655786. |
furthermore, forkhead box o3a (foxo3a) has been reported to be a critical gene in cell apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhan Sun, Bin Yan, Wen Yan Yu, Xueping Yao, Xiaojuan Ma, Geli Sheng, Qi M. Vitexin attenuates acute doxorubicin cardiotoxicity in rats via the suppression of oxidative stress, inflammation and apoptosis and the activation of FOXO3a. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27588105. |
vitexin attenuates acute doxorubicin cardiotoxicity in rats via the suppression of oxidative stress, inflammation and apoptosis and the activation of foxo3a. |
2020-09-29 |
2023-08-13 |
rat |
| Lich Thi Nguyen, Yeon-Hee Lee, Ashish Ranjan Sharma, Jong-Bong Park, Supriya Jagga, Garima Sharma, Sang-Soo Lee, Ju-Suk Na. Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 21. issue 2. 2020-09-29. PMID:28280414. |
quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of foxo3a activity. |
2020-09-29 |
2023-08-13 |
Not clear |
| Lich Thi Nguyen, Yeon-Hee Lee, Ashish Ranjan Sharma, Jong-Bong Park, Supriya Jagga, Garima Sharma, Sang-Soo Lee, Ju-Suk Na. Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 21. issue 2. 2020-09-29. PMID:28280414. |
knockdown of foxo3a caused significant reduction in the effect of quercetin on cell apoptosis and cell cycle arrest. |
2020-09-29 |
2023-08-13 |
Not clear |
| Lich Thi Nguyen, Yeon-Hee Lee, Ashish Ranjan Sharma, Jong-Bong Park, Supriya Jagga, Garima Sharma, Sang-Soo Lee, Ju-Suk Na. Quercetin induces apoptosis and cell cycle arrest in triple-negative breast cancer cells through modulation of Foxo3a activity. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 21. issue 2. 2020-09-29. PMID:28280414. |
taken together, our study suggests that quercetin induces apoptosis and cell cycle arrest via modification of foxo3a signaling in triple-negative breast cancer cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Kai Quan, Xin Zhang, Kun Fan, Peixi Liu, Qi Yue, Bo Li, Jinfeng Wu, Baojun Liu, Yang Xu, Wei Hua, Wei Zh. Icariside II induces cell cycle arrest and apoptosis in human glioblastoma cells through suppressing Akt activation and potentiating FOXO3a activity. American journal of translational research. vol 9. issue 5. 2020-09-29. PMID:28560001. |
icariside ii induces cell cycle arrest and apoptosis in human glioblastoma cells through suppressing akt activation and potentiating foxo3a activity. |
2020-09-29 |
2023-08-13 |
human |
| Xin Zhu, Yunfang Yu, Xiuxiu Hou, Jiajie Xu, Zhuo Tan, Xilin Nie, Zhiqiang Ling, Minghua G. Expression of PIM-1 in salivary gland adenoid cystic carcinoma: Association with tumor progression and patients' prognosis. Oncology letters. vol 15. issue 1. 2020-09-29. PMID:29399171. |
the present study investigated the clinical significance of the pim-1 protein, apoptosis status and apoptosis-associated proteins, including forkhead box o3a (foxo3a), b cell lymphoma-2 (bcl-2) and bcl-2-associted agonist of cell death (bad), were investigated in salivary gland adenoid cystic carcinoma (acc) tissues. |
2020-09-29 |
2023-08-13 |
Not clear |
| Luo Li, Shuangcheng Chen, Yunwei Sun, Lu Kong, Guangping Liu, Pin Gu. Matrine inhibits the proliferation of pituitary tumor cells by decreasing Foxo3a phosphorylation and promoting Foxo3a nuclear localization. Experimental and therapeutic medicine. vol 17. issue 5. 2020-09-29. PMID:30988763. |
matrine increased the nuclear localization of foxo3a and the expression of proapoptotic genes, such as bcl2 like 11 and bcl2 associated x apoptosis regulator, and inhibited the levels of cytoplasmic foxo3a. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jingze Zhang, Haiming Xu, Licheng Gong, Long Li. MicroRNA-132 protects H9c2 cells against oxygen and glucose deprivation-evoked injury by targeting FOXO3A. Journal of cellular physiology. vol 235. issue 1. 2020-08-21. PMID:31210352. |
we discovered that silenced foxo3a alleviated ogd-evoked cell injury in h9c2 cells via facilitating cell viability, hindering apoptosis and restraining cell arrest at g0/g1 phase. |
2020-08-21 |
2023-08-13 |
human |
| Yongjian Guo, Yue Zhao, Yuxin Zhou, Xiaoqing Tang, Zhiyu Li, Xiaotang Wan. LZ-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing FOXO3a via blocking autophagy flux in NSCLC cells. Cell death & disease. vol 10. issue 7. 2020-07-13. PMID:31217472. |
lz-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing foxo3a via blocking autophagy flux in nsclc cells. |
2020-07-13 |
2023-08-13 |
human |
| Yongjian Guo, Yue Zhao, Yuxin Zhou, Xiaoqing Tang, Zhiyu Li, Xiaotang Wan. LZ-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing FOXO3a via blocking autophagy flux in NSCLC cells. Cell death & disease. vol 10. issue 7. 2020-07-13. PMID:31217472. |
however, inhibition of autophagosome formation abolished foxo3a stabilization and apoptosis induced by lz-101. |
2020-07-13 |
2023-08-13 |
human |
| Yongjian Guo, Yue Zhao, Yuxin Zhou, Xiaoqing Tang, Zhiyu Li, Xiaotang Wan. LZ-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing FOXO3a via blocking autophagy flux in NSCLC cells. Cell death & disease. vol 10. issue 7. 2020-07-13. PMID:31217472. |
in conclusion, our findings indicated that lz-101 induces mitochondrial apoptosis and stabilizes foxo3a by blocking autophagy flux. |
2020-07-13 |
2023-08-13 |
human |
| Wen-Zhen Shi, Ye Tian, Juan L. GCN2 suppression attenuates cerebral ischemia in mice by reducing apoptosis and endoplasmic reticulum (ER) stress through the blockage of FoxO3a-regulated ROS production. Biochemical and biophysical research communications. vol 516. issue 1. 2020-07-13. PMID:31255283. |
in addition, forkhead box o 3a (foxo3a), involved in the reactive oxygen species (ros) production, was increased during ogd/r stimulation-regulated apoptosis and ers, which could be abrogated by gcn2 suppression. |
2020-07-13 |
2023-08-13 |
mouse |
| Ge Zhou, Rong-Kui Hu, Gui-Cheng Xia, Shi-Hai Yan, Qing-Ling Ren, Juan Zhao, Fei-Hong Wang, Cheng-Cai Huang, Qi Yao, Yong Tan, Ning-Wei Zha. Tyrosine nitrations impaired intracellular trafficking of FSHR to the cell surface and FSH-induced Akt-FoxO3a signaling in human granulosa cells. Aging. vol 11. issue 10. 2020-06-17. PMID:31097679. |
akt-induced inactivation of foxo3a was required for the repression of fsh on granulosa cell apoptosis. |
2020-06-17 |
2023-08-13 |
human |
| Xiaoting Li, Kun Liu, Wei Zhou, Zhe Jian. MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a. Cancer biomarkers : section A of Disease markers. vol 27. issue 1. 2020-06-08. PMID:31771044. |
mir-155 targeting foxo3a regulates oral cancer cell proliferation, apoptosis, and ddp resistance through targeting foxo3a. |
2020-06-08 |
2023-08-13 |
Not clear |
| Xiaoting Li, Kun Liu, Wei Zhou, Zhe Jian. MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a. Cancer biomarkers : section A of Disease markers. vol 27. issue 1. 2020-06-08. PMID:31771044. |
in this study, we established a cisplatin-resistant cell line of oral cancer to compare the expression of mir-155 and foxo3a in parental oral cancer cells, and explore whether mir-155 regulates the expression of foxo3a and affects the proliferation and apoptosis of oral cancer cells. |
2020-06-08 |
2023-08-13 |
Not clear |
| Xiaoting Li, Kun Liu, Wei Zhou, Zhe Jian. MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a. Cancer biomarkers : section A of Disease markers. vol 27. issue 1. 2020-06-08. PMID:31771044. |
compared with the mir-nc group, transfection of mir-155 inhibitor markedly increased the expression of foxo3a in kb/ddp cells, which significantly attenuated cell proliferation and enhanced apoptosis in ddp-treated cells. |
2020-06-08 |
2023-08-13 |
Not clear |
| Xiaoting Li, Kun Liu, Wei Zhou, Zhe Jian. MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a. Cancer biomarkers : section A of Disease markers. vol 27. issue 1. 2020-06-08. PMID:31771044. |
inhibition of mir-155 expression upregulated foxo3a expression, restrained oral cancer cell proliferation, promoted cell apoptosis, and enhanced ddp sensitivity in oral cancer cells. |
2020-06-08 |
2023-08-13 |
Not clear |
| Fuxing Lin, Jie Yang, Umair Muhammad, Jing Sun, Zhenghua Huang, Wei Li, Fengxia Lv, Zhaoxin L. Bacillomycin D-C16 triggers apoptosis of gastric cancer cells through the PI3K/Akt and FoxO3a signaling pathways. Anti-cancer drugs. vol 30. issue 1. 2020-06-02. PMID:30169424. |
bacillomycin d-c16 triggers apoptosis of gastric cancer cells through the pi3k/akt and foxo3a signaling pathways. |
2020-06-02 |
2023-08-13 |
Not clear |