| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xu-Xia Sui, Li-Li Luo, Jin-Jie Xu, Yu-Cai F. Evidence that FOXO3a is involved in oocyte apoptosis in the neonatal rat ovary. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 88. issue 4. 2010-12-15. PMID:20651833. |
previous studies have proposed that the forkhead transcription factor foxo3a is involved in cell cycle arrest and apoptosis and that it may also repress follicular development by inducing cell cycle arrest in ovaries. |
2010-12-15 |
2023-08-12 |
rat |
| Xu-Xia Sui, Li-Li Luo, Jin-Jie Xu, Yu-Cai F. Evidence that FOXO3a is involved in oocyte apoptosis in the neonatal rat ovary. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 88. issue 4. 2010-12-15. PMID:20651833. |
we have recently demonstrated that foxo3a induces oocyte apoptosis of neonatal rat ovaries under in vitro conditions. |
2010-12-15 |
2023-08-12 |
rat |
| Xu-Xia Sui, Li-Li Luo, Jin-Jie Xu, Yu-Cai F. Evidence that FOXO3a is involved in oocyte apoptosis in the neonatal rat ovary. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 88. issue 4. 2010-12-15. PMID:20651833. |
in the present study, we evaluated the role of foxo3a in oocyte apoptosis under in vivo conditions. |
2010-12-15 |
2023-08-12 |
rat |
| Xu-Xia Sui, Li-Li Luo, Jin-Jie Xu, Yu-Cai F. Evidence that FOXO3a is involved in oocyte apoptosis in the neonatal rat ovary. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 88. issue 4. 2010-12-15. PMID:20651833. |
these results suggest that foxo3a in the oocyte nucleus is involved in oocyte apoptosis; that is, foxo3a-positive oocytes may be the apoptotic cells. |
2010-12-15 |
2023-08-12 |
rat |
| Xu-Xia Sui, Li-Li Luo, Jin-Jie Xu, Yu-Cai F. Evidence that FOXO3a is involved in oocyte apoptosis in the neonatal rat ovary. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 88. issue 4. 2010-12-15. PMID:20651833. |
we conclude that the overexpression of foxo3a in the oocyte nucleus of neonatal rat ovaries may play an important role in the apoptosis of naked oocytes, and that bim, fasl, and p27kip1 are the key downstream factors of foxo3a. |
2010-12-15 |
2023-08-12 |
rat |
| Angela K F Lo, Christopher W Dawson, Kwok W Lo, Yanxing Yu, Lawrence S Youn. Upregulation of Id1 by Epstein-Barr virus-encoded LMP1 confers resistance to TGFbeta-mediated growth inhibition. Molecular cancer. vol 9. 2010-12-06. PMID:20565867. |
id1, a hlh protein is implicated in cell transformation and plays a role in cell proliferation, whilst foxo3a, a transcription factor controls cell integrity and homeostasis by regulating apoptosis. |
2010-12-06 |
2023-08-12 |
Not clear |
| Lauy Al-Anati, Johan Högberg, Ulla Steniu. Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis. Toxicology and applied pharmacology. vol 249. issue 2. 2010-11-24. PMID:20840854. |
this phosphorylation promotes a cytoplasmic translocation of foxo3a and p53 and our data suggest that ndl-pcbs may inhibit bp-induced apoptosis by preventing a foxo3a-dependent translocation of p53 to the cytoplasm. |
2010-11-24 |
2023-08-12 |
Not clear |
| Giovanna Ferrari-Amorotti, Samanta Antonella Mariani, Chiara Novi, Sara Cattelani, Luisa Pecorari, Francesca Corradini, Angela Rachele Soliera, Gloria Manzotti, Valentina Fragliasso, Ying Zhang, Robert V Martinez, Eric W-F Lam, Clara Guerzoni, Bruno Calabrett. The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain. The Journal of biological chemistry. vol 285. issue 40. 2010-10-26. PMID:20659895. |
expression of foxo3a, a novel c/ebpα-regulated gene, was required for apoptosis but not for differentiation induction or proliferation inhibition of k562 cells. |
2010-10-26 |
2023-08-12 |
Not clear |
| Oliver R Mikse, Daniel C Blake, Nathan R Jones, Yuan-Wan Sun, Shantu Amin, Carla J Gallagher, Philip Lazarus, Judith Weisz, Christopher R Herzo. FOXO3 encodes a carcinogen-activated transcription factor frequently deleted in early-stage lung adenocarcinoma. Cancer research. vol 70. issue 15. 2010-09-13. PMID:20631076. |
here, we show that foxo3a is functionally activated and augments the level of caspase-dependent apoptosis in cells exposed to this dna-damaging carcinogen. |
2010-09-13 |
2023-08-12 |
human |
| Jinling Hou, Zhao Zhong Chong, Yan Chen Shang, Kenneth Maies. Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation. Current neurovascular research. vol 7. issue 2. 2010-08-10. PMID:20370652. |
the ability of sirt1 to avert apoptosis employs the activation of protein kinase b (akt1), the post-translational phosphorylation of the forkhead member foxo3a, the blocked trafficking of foxo3a to the nucleus, and the inhibition of foxo3a to initiate a "pro-apoptotic" program as shown by complimentary gene knockdown studies of foxo3a. |
2010-08-10 |
2023-08-12 |
Not clear |
| Masaki Shiota, Akira Yokomizo, Eiji Kashiwagi, Yasuhiro Tada, Junichi Inokuchi, Katsunori Tatsugami, Kentaro Kuroiwa, Takeshi Uchiumi, Narihito Seki, Seiji Nait. Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin. Cancer science. vol 101. issue 5. 2010-07-01. PMID:20210796. |
foxo3a is a member of the foxo transcription factor family, which modulates the expression of genes involved in dna damage repair, apoptosis, and other cellular processes. |
2010-07-01 |
2023-08-12 |
Not clear |
| Kun Wang, Pei-Feng L. Foxo3a regulates apoptosis by negatively targeting miR-21. The Journal of biological chemistry. vol 285. issue 22. 2010-06-17. PMID:20371612. |
foxo3a regulates apoptosis by negatively targeting mir-21. |
2010-06-17 |
2023-08-12 |
Not clear |
| Kun Wang, Pei-Feng L. Foxo3a regulates apoptosis by negatively targeting miR-21. The Journal of biological chemistry. vol 285. issue 22. 2010-06-17. PMID:20371612. |
here we report that the transcriptional factor foxo3a initiates apoptosis by transcriptionally repressing mir-21 expression. |
2010-06-17 |
2023-08-12 |
Not clear |
| Kun Wang, Pei-Feng L. Foxo3a regulates apoptosis by negatively targeting miR-21. The Journal of biological chemistry. vol 285. issue 22. 2010-06-17. PMID:20371612. |
our data suggest that foxo3a negatively regulates mir-21 in initiating apoptosis. |
2010-06-17 |
2023-08-12 |
Not clear |
| Shikha Khatri, Hasmik Yepiskoposyan, Catherine A Gallo, Preeti Tandon, David R Pla. FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. The Journal of biological chemistry. vol 285. issue 21. 2010-06-14. PMID:20371605. |
we find that foxo3a knockdown is sufficient to induce apoptosis resistance in conjunction with elevated glycolysis. |
2010-06-14 |
2023-08-12 |
Not clear |
| Yasuhiko Sakoe, Kumi Sakoe, Keita Kirito, Keiya Ozawa, Norio Komats. FOXO3A as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia. Blood. vol 115. issue 18. 2010-05-25. PMID:20215638. |
foxo3a as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia. |
2010-05-25 |
2023-08-12 |
Not clear |
| Yasuhiko Sakoe, Kumi Sakoe, Keita Kirito, Keiya Ozawa, Norio Komats. FOXO3A as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia. Blood. vol 115. issue 18. 2010-05-25. PMID:20215638. |
as expected, transfection of a short hairpin rna (shrna) oligonucleotide specific for foxo3a significantly inhibited atra-induced granulocytic differentiation and apoptosis in nb4 cells. |
2010-05-25 |
2023-08-12 |
Not clear |
| Yasuhiko Sakoe, Kumi Sakoe, Keita Kirito, Keiya Ozawa, Norio Komats. FOXO3A as a key molecule for all-trans retinoic acid-induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia. Blood. vol 115. issue 18. 2010-05-25. PMID:20215638. |
furthermore, forced expression of active foxo3a in the nucleus induced trail production and apoptosis in nb4/ra cells. |
2010-05-25 |
2023-08-12 |
Not clear |
| Fanny Turrel-Davin, Anne Tournadre, Alexandre Pachot, Béatrice Arnaud, Marie-Angélique Cazalis, Bruno Mougin, Pierre Miosse. FoxO3a involved in neutrophil and T cell survival is overexpressed in rheumatoid blood and synovial tissue. Annals of the rheumatic diseases. vol 69. issue 4. 2010-04-16. PMID:19435720. |
foxo3a is a transcriptional factor implicated in cell cycle regulation and apoptosis. |
2010-04-16 |
2023-08-12 |
Not clear |
| Fanny Turrel-Davin, Anne Tournadre, Alexandre Pachot, Béatrice Arnaud, Marie-Angélique Cazalis, Bruno Mougin, Pierre Miosse. FoxO3a involved in neutrophil and T cell survival is overexpressed in rheumatoid blood and synovial tissue. Annals of the rheumatic diseases. vol 69. issue 4. 2010-04-16. PMID:19435720. |
since rheumatoid arthritis (ra) is associated with apoptosis defects, the expression level, regulation and phosphorylation status of foxo3a was investigated in blood and synovium from patients with ra. |
2010-04-16 |
2023-08-12 |
Not clear |