| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Picone, D Nuzzo, L Caruana, E Messina, V Scafidi, M Di Carl. Curcumin induces apoptosis in human neuroblastoma cells via inhibition of AKT and Foxo3a nuclear translocation. Free radical research. vol 48. issue 12. 2015-09-11. PMID:25179440. |
curcumin induces apoptosis in human neuroblastoma cells via inhibition of akt and foxo3a nuclear translocation. |
2015-09-11 |
2023-08-13 |
human |
| Y Tatsumi, R Takano, M S Islam, T Yokochi, M Itami, Y Nakamura, A Nakagawar. BMCC1, which is an interacting partner of BCL2, attenuates AKT activity, accompanied by apoptosis. Cell death & disease. vol 6. 2015-09-11. PMID:25611382. |
bmcc1 upregulation was correlated with the activation of forkhead box-o3a (foxo3a) (a downstream inducer of apoptosis, which is suppressed by akt) and induction of bcl2 inhibitor bim, suggesting that bmcc1 negatively regulates phosphorylation pathway of akt, resulted in apoptosis. |
2015-09-11 |
2023-08-13 |
human |
| Zhenxing Liu, Yingzheng Wang, Shuan Zhao, Jingyou Zhang, Yi Wu, Shenming Zen. Imidazole inhibits autophagy flux by blocking autophagic degradation and triggers apoptosis via increasing FoxO3a-Bim expression. International journal of oncology. vol 46. issue 2. 2015-08-21. PMID:25422052. |
in addition, sirna-mediated silencing of foxo3a effectively attenuated imidazole-induced bim upregulation and cell death, indicating direct involvement of this pathway in the imidazole-induced apoptosis. |
2015-08-21 |
2023-08-13 |
Not clear |
| Raewyn C Poulsen, Andrew J Carr, Philippa A Hulle. Cell proliferation is a key determinant of the outcome of FOXO3a activation. Biochemical and biophysical research communications. vol 462. issue 1. 2015-08-11. PMID:25935481. |
in peroxide-treated cells cultured in low serum media, foxo3a inhibited cell proliferation and protected against apoptosis. |
2015-08-11 |
2023-08-13 |
human |
| Raewyn C Poulsen, Andrew J Carr, Philippa A Hulle. Cell proliferation is a key determinant of the outcome of FOXO3a activation. Biochemical and biophysical research communications. vol 462. issue 1. 2015-08-11. PMID:25935481. |
similarly, in tenocytes transduced to over-express foxo3a, cell proliferation was inhibited and level of apoptosis unchanged in cells cultured in low serum. |
2015-08-11 |
2023-08-13 |
human |
| Raewyn C Poulsen, Andrew J Carr, Philippa A Hulle. Cell proliferation is a key determinant of the outcome of FOXO3a activation. Biochemical and biophysical research communications. vol 462. issue 1. 2015-08-11. PMID:25935481. |
conversely, addition of a chk2 inhibitor to peroxide-treated or foxo3a-expressing cells overrode the inhibitory effect of foxo3a on cell proliferation and led to increased apoptosis in cells cultured in low serum. |
2015-08-11 |
2023-08-13 |
human |
| Yu-Qiang Wang, Qing Cao, Fei Wang, Li-Ya Huang, Tian-Tian Sang, Fang Liu, Shu-Yan Che. SIRT1 Protects Against Oxidative Stress-Induced Endothelial Progenitor Cells Apoptosis by Inhibiting FOXO3a via FOXO3a Ubiquitination and Degradation. Journal of cellular physiology. vol 230. issue 9. 2015-08-04. PMID:25640014. |
sirt1 protects against oxidative stress-induced endothelial progenitor cells apoptosis by inhibiting foxo3a via foxo3a ubiquitination and degradation. |
2015-08-04 |
2023-08-13 |
human |
| Yu-Qiang Wang, Qing Cao, Fei Wang, Li-Ya Huang, Tian-Tian Sang, Fang Liu, Shu-Yan Che. SIRT1 Protects Against Oxidative Stress-Induced Endothelial Progenitor Cells Apoptosis by Inhibiting FOXO3a via FOXO3a Ubiquitination and Degradation. Journal of cellular physiology. vol 230. issue 9. 2015-08-04. PMID:25640014. |
to sum up, our work demonstrated that sirt1 had a pivotally protective role in the regulation of epcs apoptosis induced by h(2)o(2) and that sirt1 protected against apoptosis by inhibiting foxo3a via foxo3a ubiquitination and subsequent degradation. |
2015-08-04 |
2023-08-13 |
human |
| María Paula Ceballos, Juan Pablo Parody, Ariel Darío Quiroga, María Laura Casella, Daniel Eleazar Francés, María Cecilia Larocca, Cristina Ester Carnovale, María de Luján Alvarez, María Cristina Carrill. FoxO3a nuclear localization and its association with β-catenin and Smads in IFN-α-treated hepatocellular carcinoma cell lines. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 34. issue 11. 2015-07-20. PMID:24950290. |
forkhead box o-class 3a (foxo3a) participates in proliferation and apoptosis and interacts with β-catenin and smads. |
2015-07-20 |
2023-08-13 |
Not clear |
| Lauy Al-Anati, Sandeep Kadekar, Johan Högberg, Ulla Steniu. PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a. Chemico-biological interactions. vol 219. 2015-07-08. PMID:24954032. |
this effect was associated with an attenuated pah-induced apoptosis and with decreased levels of phosphorylated foxo3a thr32. |
2015-07-08 |
2023-08-13 |
Not clear |
| Lauy Al-Anati, Sandeep Kadekar, Johan Högberg, Ulla Steniu. PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a. Chemico-biological interactions. vol 219. 2015-07-08. PMID:24954032. |
we found that inhibition of pp2a phosphatase restored levels of phosphorylated foxo3a, led to cytosolic translocation of p53, and activated bap-induced p53-mediated apoptosis. |
2015-07-08 |
2023-08-13 |
Not clear |
| Lauy Al-Anati, Sandeep Kadekar, Johan Högberg, Ulla Steniu. PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a. Chemico-biological interactions. vol 219. 2015-07-08. PMID:24954032. |
our data indicate interplay between p53, foxo3a and 14-3-3 leading to an attenuated bap induced apoptosis in cells co-exposed to tcdd, pcb 153 or estradiol. |
2015-07-08 |
2023-08-13 |
Not clear |
| X Li, N Du, Q Zhang, J Li, X Chen, X Liu, Y Hu, W Qin, N Shen, C Xu, Z Fang, Y Wei, R Wang, Z Du, Y Zhang, Y L. MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy. Cell death & disease. vol 5. 2015-06-18. PMID:25341033. |
moreover, mir-30d directly repressed foxo3a expression and its downstream protein, apoptosis repressor with caspase recruitment domain (arc). |
2015-06-18 |
2023-08-13 |
rat |
| Juan P Parody, Maria P Ceballos, Ariel D Quiroga, Daniel E Frances, Cristina E Carnovale, Gerardo B Pisani, Maria L Alvarez, Maria C Carrill. FoxO3a modulation and promotion of apoptosis by interferon-α2b in rat preneoplastic liver. Liver international : official journal of the International Association for the Study of the Liver. vol 34. issue 10. 2015-06-15. PMID:24289330. |
foxo3a modulation and promotion of apoptosis by interferon-α2b in rat preneoplastic liver. |
2015-06-15 |
2023-08-12 |
rat |
| Juan P Parody, Maria P Ceballos, Ariel D Quiroga, Daniel E Frances, Cristina E Carnovale, Gerardo B Pisani, Maria L Alvarez, Maria C Carrill. FoxO3a modulation and promotion of apoptosis by interferon-α2b in rat preneoplastic liver. Liver international : official journal of the International Association for the Study of the Liver. vol 34. issue 10. 2015-06-15. PMID:24289330. |
foxo3a, a member of the foxo family of transcription factors, is expressed in adult liver and modulates the expression of genes involved in apoptosis. |
2015-06-15 |
2023-08-12 |
rat |
| Eveline A I F Queiroz, Stephanie Puukila, Rosangela Eichler, Sandra C Sampaio, Heidi L Forsyth, Simon J Lees, Aneli M Barbosa, Robert F H Dekker, Zuleica B Fortes, Neelam Khape. Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells. PloS one. vol 9. issue 5. 2015-06-11. PMID:24858012. |
metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, ampk and foxo3a in mcf-7 breast cancer cells. |
2015-06-11 |
2023-08-13 |
Not clear |
| Eveline A I F Queiroz, Stephanie Puukila, Rosangela Eichler, Sandra C Sampaio, Heidi L Forsyth, Simon J Lees, Aneli M Barbosa, Robert F H Dekker, Zuleica B Fortes, Neelam Khape. Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells. PloS one. vol 9. issue 5. 2015-06-11. PMID:24858012. |
these results show that metformin has an antiproliferative effect associated with cell cycle arrest and apoptosis, which is mediated by oxidative stress, as well as ampk and foxo3a activation. |
2015-06-11 |
2023-08-13 |
Not clear |
| Gabriela Nestal de Moraes, Carolina Pereira Castro, Eduardo Jesus Salustiano, Matheus Lourenço Dumas, Fernanda Costas, Eric Wing-Fai Lam, Paulo Roberto Ribeiro Costa, Raquel Ciuvalschi Mai. The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors. International journal of oncology. vol 45. issue 5. 2015-05-25. PMID:25174716. |
the pterocarpanquinone lqb-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets foxo3a and foxm1 transcription factors. |
2015-05-25 |
2023-08-13 |
mouse |
| Hao Liu, Jiang Yin, Chengkun Wang, Yixue Gu, Min Deng, Zhimin H. FOXO3a mediates the cytotoxic effects of cisplatin in lung cancer cells. Anti-cancer drugs. vol 25. issue 8. 2015-05-12. PMID:24814195. |
foxo3a is a member of the foxo transcription factor family, which modulates the expression of genes involved in cell cycle arrest, apoptosis, and other cellular processes. |
2015-05-12 |
2023-08-13 |
human |
| Hao Liu, Jiang Yin, Chengkun Wang, Yixue Gu, Min Deng, Zhimin H. FOXO3a mediates the cytotoxic effects of cisplatin in lung cancer cells. Anti-cancer drugs. vol 25. issue 8. 2015-05-12. PMID:24814195. |
knockdown of foxo3a expression using small interfering rna attenuated cisplatin-induced apoptosis. |
2015-05-12 |
2023-08-13 |
human |