| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T N D Pham, M Marion, F Denizeau, C Jumari. Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 8. 2006-12-26. PMID:16809017. |
depending on the exposure conditions, cd may cause necrosis or apoptosis. |
2006-12-26 |
2023-08-12 |
rat |
| T N D Pham, M Marion, F Denizeau, C Jumari. Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 8. 2006-12-26. PMID:16809017. |
oxidative stress is believed to participate in cd toxicity but the molecular signaling responsible for cd-induced apoptosis in non-malignant liver cells still needs to be clarified. |
2006-12-26 |
2023-08-12 |
rat |
| T N D Pham, M Marion, F Denizeau, C Jumari. Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 8. 2006-12-26. PMID:16809017. |
therefore we have studied apoptosis in primary cultures of rat hepatocytes incubated with low levels of cd for short exposure times. |
2006-12-26 |
2023-08-12 |
rat |
| T N D Pham, M Marion, F Denizeau, C Jumari. Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways. Toxicology in vitro : an international journal published in association with BIBRA. vol 20. issue 8. 2006-12-26. PMID:16809017. |
studies of nuclear morphology, chromatin condensation, and oligonucleosomal dna fragmentation demonstrate that 1-5 microm cd induces apoptosis as early as 6-12 h with minor effects on mtt activity. |
2006-12-26 |
2023-08-12 |
rat |
| A V Petro. [Assessment of sulfasalazine and hydroxichloroqine hepatotoxicity in patients with rheumatic arthritis and isolated HBS-antigen positivity]. Likars'ka sprava. issue 1. 2006-12-06. PMID:17051718. |
hbs, hbe-antigenes, dna-virus b hepatitis blood test, nucleus dimensions, proliferative fga response test and immune cd 8+, cd 14+ and cd 16+ cells to fas-induced apoptosis were taken. |
2006-12-06 |
2023-08-12 |
Not clear |
| E Matalová, J Setková, J Blackburn, I Mísek, P T Sharp. CD 95 mediated apoptosis in embryogenesis: implication in tooth development. Orthodontics & craniofacial research. vol 9. issue 3. 2006-11-09. PMID:16918676. |
cd 95 mediated apoptosis in embryogenesis: implication in tooth development. |
2006-11-09 |
2023-08-12 |
Not clear |
| E Matalová, J Setková, J Blackburn, I Mísek, P T Sharp. CD 95 mediated apoptosis in embryogenesis: implication in tooth development. Orthodontics & craniofacial research. vol 9. issue 3. 2006-11-09. PMID:16918676. |
research of cd 95 mediated apoptosis has been focused particularly on cell death in the immune system and related disorders. |
2006-11-09 |
2023-08-12 |
Not clear |
| E Matalová, J Setková, J Blackburn, I Mísek, P T Sharp. CD 95 mediated apoptosis in embryogenesis: implication in tooth development. Orthodontics & craniofacial research. vol 9. issue 3. 2006-11-09. PMID:16918676. |
however, cd 95 mediated apoptosis is also involved in embryogenesis of many organs as the kidney, the lung, the intestine and tissue networks such as the nervous system. |
2006-11-09 |
2023-08-12 |
Not clear |
| Georg B T von Boyen, Martin Steinkamp, Irmlind Geerling, Max Reinshagen, Karl H Schäfer, Guido Adler, Joachim Kirsc. Proinflammatory cytokines induce neurotrophic factor expression in enteric glia: a key to the regulation of epithelial apoptosis in Crohn's disease. Inflammatory bowel diseases. vol 12. issue 5. 2006-10-10. PMID:16670534. |
imbalanced apoptosis of enterocytes is likely to be 1 of the mechanisms underlying crohn's disease (cd). |
2006-10-10 |
2023-08-12 |
Not clear |
| Georg B T von Boyen, Martin Steinkamp, Irmlind Geerling, Max Reinshagen, Karl H Schäfer, Guido Adler, Joachim Kirsc. Proinflammatory cytokines induce neurotrophic factor expression in enteric glia: a key to the regulation of epithelial apoptosis in Crohn's disease. Inflammatory bowel diseases. vol 12. issue 5. 2006-10-10. PMID:16670534. |
apoptosis of enterocytes is regulated by glial-derived neurotrophic factor (gdnf), which is increased in cd. |
2006-10-10 |
2023-08-12 |
Not clear |
| Jennifer Thompson, Eoin Hipwell, Hui Voon Loo, John Banniga. Effects of cadmium on cell death and cell proliferation in chick embryos. Reproductive toxicology (Elmsford, N.Y.). vol 20. issue 4. 2006-09-29. PMID:16183249. |
pre-treatment with zinc acetate (10x the dose of cd) prevented gross malformation, apoptosis and the effect of cd on peridermal proliferation. |
2006-09-29 |
2023-08-12 |
chicken |
| Chwen-Ming Shih, Wun-Chang Ko, Liang-Yo Yang, Chien-Ju Lin, Jui-Sheng Wu, Tsui-Yun Lo, Shwu-Huey Wang, Chien-Tsu Che. Detection of apoptosis and necrosis in normal human lung cells using 1H NMR spectroscopy. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965095. |
cadmium (cd) and mercury (hg) induced apoptosis and necrosis in mrc-5 cells, respectively, as revealed by phosphatidylserine externalization on a flow cytometer. |
2006-09-11 |
2023-08-12 |
human |
| Chwen-Ming Shih, Wun-Chang Ko, Liang-Yo Yang, Chien-Ju Lin, Jui-Sheng Wu, Tsui-Yun Lo, Shwu-Huey Wang, Chien-Tsu Che. Detection of apoptosis and necrosis in normal human lung cells using 1H NMR spectroscopy. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965095. |
the spectral intensity ratio of methylene (ch2) resonance (at 1.3 ppm) to methyl (ch3) resonance (at 0.9 ppm) was directly proportional to the percentage of apoptosis and strongly and positively correlated with pi staining after cd treatment (r2 = 0.9868, p < 0.01). |
2006-09-11 |
2023-08-12 |
human |
| Yung-Luen Shih, Chien-Ju Lin, Sheng-Wei Hsu, Sheng-Hao Wang, Wei-Li Chen, Mei-Tsu Lee, Yau-Huei Wei, Chwen-Ming Shi. Cadmium toxicity toward caspase-independent apoptosis through the mitochondria-calcium pathway in mtDNA-depleted cells. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965096. |
pretreatment with z-vad-fmk, a broad-spectrum caspase inhibitor, failed to prevent apoptosis following cd exposure. |
2006-09-11 |
2023-08-12 |
Not clear |
| Yung-Luen Shih, Chien-Ju Lin, Sheng-Wei Hsu, Sheng-Hao Wang, Wei-Li Chen, Mei-Tsu Lee, Yau-Huei Wei, Chwen-Ming Shi. Cadmium toxicity toward caspase-independent apoptosis through the mitochondria-calcium pathway in mtDNA-depleted cells. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965096. |
this led us to conclude that mtdna-depleted cells provide an alternative pathway for cd to conduct caspase-independent apoptosis through a mitochondria-calcium mechanism. |
2006-09-11 |
2023-08-12 |
Not clear |
| Neelima Pathak, Shashi Khandelwa. Modulation of cadmium induced alterations in murine thymocytes by piperine: oxidative stress, apoptosis, phenotyping and blastogenesis. Biochemical pharmacology. vol 72. issue 4. 2006-09-11. PMID:16780805. |
modulation of oxidative stress has earlier been reported to reduce cd induced apoptosis in murine lymphocytes. |
2006-09-11 |
2023-08-12 |
Not clear |
| Deqiang Li, Rima Roze. Maternal folate deficiency affects proliferation, but not apoptosis, in embryonic mouse heart. The Journal of nutrition. vol 136. issue 7. 2006-07-20. PMID:16772436. |
because low folate and absent mthfr activity were shown to affect proliferation and apoptosis in developing neural tissue, we examined these processes in the myocardium of embryos from mthfr +/+ and mthfr +/- mice fed control diets (cd) or folic acid-deficient diets (fadd). |
2006-07-20 |
2023-08-12 |
mouse |
| Jianxun Xie, Zahir A Shaik. Cadmium-induced apoptosis in rat kidney epithelial cells involves decrease in nuclear factor-kappa B activity. Toxicological sciences : an official journal of the Society of Toxicology. vol 91. issue 1. 2006-06-21. PMID:16478757. |
renal epithelial cells undergo apoptosis upon exposure to cadmium (cd). |
2006-06-21 |
2023-08-12 |
rat |
| Jianxun Xie, Zahir A Shaik. Cadmium-induced apoptosis in rat kidney epithelial cells involves decrease in nuclear factor-kappa B activity. Toxicological sciences : an official journal of the Society of Toxicology. vol 91. issue 1. 2006-06-21. PMID:16478757. |
by flow cytometry, 14.6 and 30.5% apoptosis was detected at 6 and 12 h after stopping the cd exposure. |
2006-06-21 |
2023-08-12 |
rat |
| Seon-Hee Oh, Sung-Chul Li. A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation. Toxicology and applied pharmacology. vol 212. issue 3. 2006-06-01. PMID:16169029. |
cd was found to induce apoptosis in the hepg2 cells in a time- and dose-dependent fashion, as confirmed by dna fragmentation analysis and tunel staining. |
2006-06-01 |
2023-08-12 |
Not clear |