| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dashuan Li, Chaolian Yang, Lu Sun, Zhenqin Zhao, Jiaqi Liu, Cheng Zhang, Dali Sun, Qinghai Zhan. High fluoride aggravates cadmium-mediated nephrotoxicity of renal tubular epithelial cells through ROS-PINK1/Parkin pathway. The Science of the total environment. 2024-09-05. PMID:39236818. |
the interactive influence between f and cd in oxidative stress, apoptosis, and mitochondrial autophagy of renal tubular epithelial cells was explored. |
2024-09-05 |
2024-09-08 |
human |
| Jiaqiao Zhu, Zhonggui Gong, Xueru Wang, Kanglei Zhang, Yonggang Ma, Hui Zou, Ruilong Song, Hongyan Zhao, Zongping Liu, Wenxuan Don. mTORC1 and mTORC2 Co-Protect against Cadmium-Induced Renal Tubular Epithelial Cell Apoptosis and Acute Kidney Injury by Regulating Protein Kinase B. Journal of agricultural and food chemistry. 2024-09-02. PMID:39219293. |
inhibition of mtorc1 or mtorc2 exacerbated cd-induced kidney cell apoptosis, suggesting that both proteins exert antiapoptotic effects under cd exposure. |
2024-09-02 |
2024-09-04 |
mouse |
| Xingyu Chen, Wenqian Sun, Yanting Song, Shangong Wu, Shouqi Xie, Wen Xiong, Chengdong Peng, Yu Peng, Zhengxiang Wang, Sovan Lek, Christer Hogstrand, Mette Sørensen, Lei Pan, Dong Li. Acute waterborne cadmium exposure induces liver ferroptosis in Channa argus. Ecotoxicology and environmental safety. vol 283. 2024-08-30. PMID:39213749. |
currently, autophagy, apoptosis and endoplasmic reticulum stress were reported in cd exposed fish liver, and if there are other mechanisms (such as ferroptosis) and relevant signaling pathways involved in fish remains unknown. |
2024-08-30 |
2024-09-04 |
Not clear |
| Yifeng Dai, Xijin Xu, Xia Huo, Joost H N Schuitemaker, Marijke M Faa. Differential effect of lead and cadmium on mitochondrial function and NLRP3 inflammasome activation in human trophoblast. The Journal of physiology. 2024-08-28. PMID:39197088. |
however, pb under hypoxia induced a decrease of ΔΨ and promoted apoptosis of bewo cells, but cd did not induce a reduction in ΔΨ in the three trophoblast cell lines under any conditions. |
2024-08-28 |
2024-08-31 |
human |
| Xiaobing Huang, Qunshan Ye, Wenyu Dai, Jingming Zheng, Yimin Li, Cheng Wang, Zhenhuan Luo, Jing Yang, Wenyan Zhuo, Qin-Li Wa. Cadmium exposure induces multigenerational inheritance of germ cell apoptosis and fertility suppression in Caenorhabditis elegans. Environment international. vol 191. 2024-08-19. PMID:39159515. |
the results showed that cd exposure leads to an increase in germ cell apoptosis and a decrease in fertility, which can be passed down to subsequent generations. |
2024-08-19 |
2024-08-22 |
caenorhabditis_elegans |
| Xiaobing Huang, Qunshan Ye, Wenyu Dai, Jingming Zheng, Yimin Li, Cheng Wang, Zhenhuan Luo, Jing Yang, Wenyan Zhuo, Qin-Li Wa. Cadmium exposure induces multigenerational inheritance of germ cell apoptosis and fertility suppression in Caenorhabditis elegans. Environment international. vol 191. 2024-08-19. PMID:39159515. |
further analysis revealed that transcription factors daf-16/foxo and skn-1/nrf2 play essential roles in responding to cd exposure and in the transgenerational induction of germ cell apoptosis. |
2024-08-19 |
2024-08-22 |
caenorhabditis_elegans |
| Jingya Li, Xianlei Fang, Daolei Cui, Ziya Ma, Ji Yang, Youya Niu, Hai Liu, Ping Xian. Mechanistic insights into cadmium exacerbating 2-Ethylhexyl diphenyl phosphate-induced human keratinocyte toxicity: Oxidative damage, cell apoptosis, and tight junction disruption. Ecotoxicology and environmental safety. vol 283. 2024-08-13. PMID:39137464. |
moreover, cd exacerbated ehdpp-induced mitochondrial disorder and cellular apoptosis, which was evidenced by a reduction in mitochondrial membrane potential and an elevation of cyt-c and caspase-3 mrna expression. |
2024-08-13 |
2024-08-16 |
human |
| Jingya Li, Xianlei Fang, Daolei Cui, Ziya Ma, Ji Yang, Youya Niu, Hai Liu, Ping Xian. Mechanistic insights into cadmium exacerbating 2-Ethylhexyl diphenyl phosphate-induced human keratinocyte toxicity: Oxidative damage, cell apoptosis, and tight junction disruption. Ecotoxicology and environmental safety. vol 283. 2024-08-13. PMID:39137464. |
taken together, oxidative damage, cell apoptosis, and tight junction disruption played a crucial role in ehdpp + cd triggered cytotoxicity in hacat cells. |
2024-08-13 |
2024-08-16 |
human |
| Qingyu Li, Yuchen Li, Jianlin Zhu, Zhangpin Liu, Yi Sun, Yake Lv, Jingwen Li, Lingfeng Luo, Chenyun Zhang, Wenchang Zhan. Cadmium Exposure in Male Rats Results in Ovarian Granulosa Cell Apoptosis in Female Offspring and Paternal Genetic Effects. Environmental toxicology. 2024-08-09. PMID:39119833. |
the aim of this study was to investigate whether the damage to male offspring induced by cadmium (cd) exposure during embryonic period leads to the apoptosis of ovarian granulosa cells (ogcs) in the next generation of female offspring, and whether this apoptosis in the offspring was due to paternal genetic effects. |
2024-08-09 |
2024-08-12 |
rat |
| Xiaoqian Huang, Junzhao Yuan, Jianhong Gu, Yassar Abbas, Yan Yuan, Zongping Liu, Hui Zou, Jianchun Bia. Protective effect of honokiol on cadmium-induced liver injury in chickens. Poultry science. vol 103. issue 10. 2024-07-27. PMID:39067123. |
hnk alleviated cd induced pathological and ultrastructure damage of liver tissue and liver cell that leads apoptosis. |
2024-07-27 |
2024-08-02 |
chicken |
| Jie Wu, Qizi Yin, Yi Wang, Rong Wang, Wenjing Gong, Yihang Chen, Mingming Zhang, Yehao Liu, Yanli J. Integrated transcriptome and metabolomic analyses uncover the mechanism of cadmium-caused mouse spermatogonia apoptosis via inducing endoplasmic reticulum stress. Reproductive toxicology (Elmsford, N.Y.). 2024-07-22. PMID:39038763. |
cadmium (cd) is a well-recognized male reproductive toxicant that can cause testicular germ cell apoptosis. |
2024-07-22 |
2024-07-25 |
mouse |
| Qian Zhang, Shuting Li, Jing Fang, Yue Hao, Junge Lu, Lu Zhang, Minmin Zhang, Li Zhang, Yihe Wang, Yu Zhang, Hongying Du, Yuan Gao, Zuosen Yang, Wei Sun, Lingjun Yan, Guowei Pa. The combined effects of polystyrene of different sizes and cadmium in mouse kidney tissues. Ecotoxicology and environmental safety. vol 281. 2024-06-29. PMID:38944012. |
kidney damage was evaluated in male mice gavaged with ps (diameter, 100 nm and/or 1 μm) and cd for 25 days.the results showed that ps at 100 nm caused more severe oxidative damage and cell apoptosis than ps at 1 μm. |
2024-06-29 |
2024-07-02 |
mouse |
| Rastee H Saeed, Zirak Faqe Ahmed Abdulrahman, Dara K Mohamma. Exploring the interplay between microRNA expression and DNA mutation analysis in AML patients. Saudi journal of biological sciences. vol 31. issue 7. 2024-06-04. PMID:38831894. |
mutations in aml can alter mirna profiles, which can affect the expression of cd markers and contribute to disease progression by influencing cellular processes such as differentiation, proliferation, and apoptosis. |
2024-06-04 |
2024-06-06 |
Not clear |
| Min Zhang, Xue Song, Shengbao Liu, Nuo Zhang, Ming Yang, Pengcheng Gao, Zhijun Geng, Lugen Zuo, Xiaofeng Zhang, Lian Wang, Yueyue Wang, Jing Li, Jianguo H. Magnolin inhibits intestinal epithelial cell apoptosis alleviating Crohn's disease-like colitis by suppressing the PI3K/AKT signalling pathway. International immunopharmacology. vol 134. 2024-05-11. PMID:38733829. |
previous reports have shown that preventing excessive intestinal epithelial cell (iec) apoptosis is a crucial approach for protecting the intestinal barrier in patients with crohn's disease (cd). |
2024-05-11 |
2024-05-27 |
Not clear |
| Kong-Wen Ouyang, Tian-Tian Wang, Hua Wang, Ye-Xin Luo, Yi-Fan Hu, Xin-Mei Zheng, Qing Ling, Kai-Wen Wang, Yong-Wei Xiong, Jin Zhang, Wei Chang, Yu-Feng Zhang, Zhi Yuan, Hao Li, Lan Gao, De-Xiang Xu, Hua-Long Zhu, Lan Yang, Hua Wan. m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure. The Science of the total environment. vol 931. 2024-05-09. PMID:38703850. |
it is well-known that environmental cd causes testicular damage by inducing classic types of cell death such as cell apoptosis and necrosis. |
2024-05-09 |
2024-05-27 |
mouse |
| Mohamed Ali Hussein, Abishek Kamalakkannan, Kamyab Valinezhad, Jhishnuraj Kannan, Nikhila Paleati, Rama Saad, André Kajdacsy-Balla, Gnanasekar Munirathina. The dynamic face of cadmium-induced Carcinogenesis: Mechanisms, emerging trends, and future directions. Current research in toxicology. vol 6. 2024-05-06. PMID:38706786. |
moreover, cd mediates apoptosis evasion, autophagy activation, and survival mechanisms. |
2024-05-06 |
2024-05-08 |
Not clear |
| Jiamei Zhu, Xueyan Dai, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, Caiying Zhan. Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes. Poultry science. vol 103. issue 5. 2024-03-27. PMID:38537407. |
the characteristic ultrastructural changes related to apoptosis and ferroptosis were observed in mo or cd or both groups. |
2024-03-27 |
2024-03-30 |
Not clear |
| Jiamei Zhu, Xueyan Dai, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, Caiying Zhan. Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes. Poultry science. vol 103. issue 5. 2024-03-27. PMID:38537407. |
besides, mo or cd or both repressed nuclear factor erythroid 2-related factor 2 (nrf2) pathway via decreasing nrf2, heme oxygenase-1 (ho-1), nad(p)h quinone oxidoreductase 1 (nqo1), glutamate-cysteine ligase catalytic subunit (gclc) and glutamate-cysteine ligase modifier subunit (gclm) mrna expression of and nrf2 protein expression, then stimulated apoptosis by elevating bcl-2 antagonist/killer-1 (bak-1), bcl-2-associated x-protein (bax), cytochrome complex (cyt-c), caspase-3 mrna expression, cleaved-caspase-3 protein expression and apoptosis rate, as well as reducing b-cell lymphoma-2 (bcl-2) mrna expression and ratio of bcl-2 to bax, and triggered ferroptosis by upregulating acyl-coa synthetase long chain family member 4 (acsl4), transferrin receptor (tfr1) and prostaglandin-endoperoxide synthase 2 (ptgs2) expression levels, and downregulating ferritin heavy chain 1 (fth1), ferritin light chain 1 (ftl1), ferroportin 1 (fpn1), solute carrier family 7 member 11 (scl7a11) and glutathione peroxidase 4 (gpx4) expression levels. |
2024-03-27 |
2024-03-30 |
Not clear |
| Jiamei Zhu, Xueyan Dai, Yan Wang, Ting Cui, Bingyan Huang, Dianyun Wang, Wenjing Pu, Caiying Zhan. Molybdenum and cadmium co-induce apoptosis and ferroptosis through inhibiting Nrf2 signaling pathway in duck (Anas platyrhyncha) testes. Poultry science. vol 103. issue 5. 2024-03-27. PMID:38537407. |
altogether, the results announced that mo or cd or both evoked apoptosis and ferroptosis by inhibiting nrf2 pathway in the testis of ducks, and co-exposure to mo and cd exacerbated these variations. |
2024-03-27 |
2024-03-30 |
Not clear |
| Zikun Zhang, Qi Wang, Xiaoge Gao, Xu Tang, Huan Xu, Wenqiang Wang, Xin Le. Reproductive toxicity of cadmium stress in male animals. Toxicology. 2024-03-24. PMID:38522818. |
therefore, this paper reviewed the toxic effects of cd on germ cells, spermatogonia somatic cells and hypothalamic-pituitary-gonadal axis (hpg axis) of male animals and its toxic action mechanisms of oxidative stress, apoptosis and autophagy from the perspectives of cytology, genetics and neuroendocrinology. |
2024-03-24 |
2024-03-27 |
Not clear |