| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ermeng Wang, Jing Liu, Chenyun Zhao, Yuan Gao, Ziru Cheng, Chien-Min Chen, Lan Wan. Isolation, cloning, and tissue distribution and functional analysis of ShP-glycoprotein in the freshwater crab Sinopotamon henanense exposed to Cd and Cd-QDs. International journal of biological macromolecules. 2023-07-09. PMID:37423454. |
the relative expression of target genes related to energy metabolism, detoxification and apoptosis was also determined in the carbs exposed to cd or cd-qds. |
2023-07-09 |
2023-08-14 |
Not clear |
| Jing Liu, Ermeng Wang, Ziru Cheng, Yuan Gao, Chienmin Chen, Ru Jia, Zhi Luo, Lan Wan. Zinc alleviates cadmium-induced reproductive toxicity via regulating ion homeostasis, metallothionein expression, and inhibiting mitochondria-mediated apoptosis in the freshwater crab Sinopotamon henanense. Ecotoxicology and environmental safety. vol 262. 2023-07-07. PMID:37418865. |
cadmium (cd) is a carcinogenic environmental pollutant that harms male reproductive systems by lowering sperm quality, impairing spermatogenesis, and causing apoptosis. |
2023-07-07 |
2023-08-14 |
human |
| Jing Liu, Ermeng Wang, Ziru Cheng, Yuan Gao, Chienmin Chen, Ru Jia, Zhi Luo, Lan Wan. Zinc alleviates cadmium-induced reproductive toxicity via regulating ion homeostasis, metallothionein expression, and inhibiting mitochondria-mediated apoptosis in the freshwater crab Sinopotamon henanense. Ecotoxicology and environmental safety. vol 262. 2023-07-07. PMID:37418865. |
cd exposure not only resulted in its accumulation but also in zn deficiency, decreased sperm survival rate, poor sperm quality, altered ultrastructure, and increased apoptosis in the testis of the crabs. |
2023-07-07 |
2023-08-14 |
human |
| Jing Liu, Ermeng Wang, Ziru Cheng, Yuan Gao, Chienmin Chen, Ru Jia, Zhi Luo, Lan Wan. Zinc alleviates cadmium-induced reproductive toxicity via regulating ion homeostasis, metallothionein expression, and inhibiting mitochondria-mediated apoptosis in the freshwater crab Sinopotamon henanense. Ecotoxicology and environmental safety. vol 262. 2023-07-07. PMID:37418865. |
however, zn supplementation effectively mitigated the aforementioned effects of cd, as demonstrated by preventing cd accumulation, increasing zn bioavailability, alleviating apoptosis, increasing mitochondrial membrane potential, decreasing reactive oxygen species (ros) levels, and restoring mt distribution. |
2023-07-07 |
2023-08-14 |
human |
| Qiuyun Xu, Yajuan Shi, Lingjie Ke, Li Qian, Xuan Zhou, Xiuqing Sha. Ciprofloxacin enhances cadmium toxicity to earthworm Eisenia fetida by altering the gut microorganism composition. Environmental pollution (Barking, Essex : 1987). 2023-06-26. PMID:37364754. |
the reactive oxygen species (ros) contents and apoptosis rate of coelomocytes were more sensitive to cd than these biochemical indicators. |
2023-06-26 |
2023-08-14 |
Not clear |
| Qiuyun Xu, Yajuan Shi, Lingjie Ke, Li Qian, Xuan Zhou, Xiuqing Sha. Ciprofloxacin enhances cadmium toxicity to earthworm Eisenia fetida by altering the gut microorganism composition. Environmental pollution (Barking, Essex : 1987). 2023-06-26. PMID:37364754. |
similarly, the toxicity of cd (5 mg/kg) to coelomocytes was promoted by cip (1 mg/kg), ros content in coelomocytes and the apoptosis rate increased by 29.2% and 113.1%, respectively, due to increased cd accumulation. |
2023-06-26 |
2023-08-14 |
Not clear |
| Seham Abou Shousha, Suzan Baheeg, Hossam Ghoneim, Malak Zoheir, Mahmoud Hemida, Yasmine Shahin. The effect of Fas/FasL pathway blocking on apoptosis and stemness within breast cancer tumor microenvironment (preclinical study). Breast disease. vol 42. issue 1. 2023-06-19. PMID:37334575. |
fas/fasl expression is linked to the maintenance of cancer stem cells (cscs) within the tme, contributing to tumor aggressiveness, metastasis, recurrence, and chemoresistance.this study is considered the first study designed to block the overexpressed fasl on the tumor cells within tme mimicking tissue culture system using rfas molecules and supplementing the fas enriched tissue culture system with blocked fas - peripheral blood mononuclear cells pbmcs (using anti-fas mab) to protect them from tumor counterattack and augment their ability to induce tumor cell apoptosis and stemness inhibition.a significantly increased level of apoptosis and decreased expression of cd 44 (cscs marker) was observed within the east tumor tissue culture system enriched with fas molecules and anti-fas treated pbmcs and the one enriched with fas molecules only compared to the breast tumor tissues cultured alone (p < 0.001). |
2023-06-19 |
2023-08-14 |
Not clear |
| Yi Sun, Wenchang Zhang, Yuchen Li, Jianlin Zhu, Chenchen Liu, Lingfeng Luo, Jin Liu, Chenyun Zhan. Multigenerational genetic effects of paternal cadmium exposure on ovarian granulosa cell apoptosis. Ecotoxicology and environmental safety. vol 262. 2023-06-14. PMID:37315360. |
to explore whether paternal cadmium (cd) exposure causes ovarian granulosa cell (gc) apoptosis in offspring and the multigenerational genetic effects. |
2023-06-14 |
2023-08-14 |
rat |
| Cao Zhaohui, Tang Cifei, Huang Di, Zeng Weijia, Han Cairui, Li Zecong, Hu Xiaob. ROS-mediated PERK-CHOP pathway plays an important role in cadmium-induced HepG2 cells apoptosis. Environmental toxicology. 2023-06-10. PMID:37300854. |
cadmium (cd) is a common heavy metal that is highly toxic to the liver, however, the exact mechanism underlying this damage accompanied by apoptosis has not been thoroughly demonstrated. |
2023-06-10 |
2023-08-14 |
Not clear |
| Chengjie Chen, Zhengsheng Zhou, Siqi Yu, Yawei Ma, Gang Wang, Xue Han, Congcong Jiao, Junjun Luan, Zhiyuan Liu, Yuanyuan Xu, Huihui Wang, Qiang Zhang, Jingqi Fu, Hua Zhou, Jingbo P. Nrf2 protects against renal fibrosis induced by chronic cadmium exposure in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-06-07. PMID:37286028. |
mechanistic studies showed that nrf2-ko mice exhibited higher levels of oxidative damage, lower antioxidant levels, and more regulated cell death, apoptosis in particular, than those in nrf2-wt mice caused by cd exposure. |
2023-06-07 |
2023-08-14 |
mouse |
| Chantal-Kristin Wenzel, Claudia von Montfort, Lara Ebbert, Niklas P Klahm, Andreas S Reichert, Wilhelm Stahl, Peter Brenneise. The natural chalcone cardamonin selectively induces apoptosis in human neuroblastoma cells. Toxicology in vitro : an international journal published in association with BIBRA. 2023-06-02. PMID:37268255. |
the natural chalcone cd specifically altered the mitochondrial membrane potential (ΔΨm), as an early marker of apoptosis, in human neuroblastoma cells. |
2023-06-02 |
2023-08-14 |
human |
| Chantal-Kristin Wenzel, Claudia von Montfort, Lara Ebbert, Niklas P Klahm, Andreas S Reichert, Wilhelm Stahl, Peter Brenneise. The natural chalcone cardamonin selectively induces apoptosis in human neuroblastoma cells. Toxicology in vitro : an international journal published in association with BIBRA. 2023-06-02. PMID:37268255. |
the natural chalcone cd selectively induced apoptosis, the programmed cell death, in sh-sy5y human neuroblastoma cells whereas nhdf being a model for normal (healthy) cells were unaffected. |
2023-06-02 |
2023-08-14 |
human |
| Srinibas Das, Indrajit Kar, Amlan Kumar Patr. Cadmium induced bioaccumulation, histopathology, gene regulation in fish and its amelioration - A review. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 79. 2023-06-01. PMID:37263063. |
exposure of cd exerts several adverse effects on general growth and development, reproductive processes, osmoregulation, morphological and histological structures, stress tolerance, and endocrine system, mainly due to changes in biological functions induced by differential expressions of several genes related to oxidative stress, apoptosis, inflammation, immunosuppressions, genotoxicity, cd chelation and carbohydrate metabolism. |
2023-06-01 |
2023-08-14 |
Not clear |
| Hasan Şimşek, Nurhan Akaras, Cihan Gür, Sefa Küçükler, Fatih Mehmet Kandemi. Beneficial effects of Chrysin on Cadmium-induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO-1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling pathways. Gene. 2023-05-24. PMID:37224935. |
in addition, cd application caused apoptosis by increasing bax, apaf-1 and caspase-3 mrna transcripts and decreasing bcl-2 mrna transcript level. |
2023-05-24 |
2023-08-14 |
rat |
| Jiawen Cui, Yuhao Liu, Zhiyu Hao, Yuhang Liu, Minna Qiu, Lu Kang, Xiaohua Teng, You Tan. Cadmium induced time-dependent kidney injury in common carp via mitochondrial pathway: Impaired mitochondrial energy metabolism and mitochondrion-dependent apoptosis. Aquatic toxicology (Amsterdam, Netherlands). 2023-05-18. PMID:37202229. |
we further revealed via histological observation that cd damaged structural integrity of kidneys, as evidenced by renal glomerulus and renal tubular injury, hallmark phenotypes of apoptosis, and mitochondrial damage, suggesting that mitochondria damage and apoptosis were involved in cd-induced kidney injury. |
2023-05-18 |
2023-08-14 |
Not clear |
| Alex Tuffour, Anthony Adebayiga Kosiba, Frank Addai Peprah, Jie Gu, Yang Zhou, Haifeng Sh. Cadmium-induced Stress: A Close Look at the Relationship between Autophagy and Apoptosis. Toxicological sciences : an official journal of the Society of Toxicology. 2023-05-11. PMID:37166467. |
cadmium (cd), a toxic heavy metal, induces apoptosis and autophagy in cells after exposure to low concentrations. |
2023-05-11 |
2023-08-14 |
Not clear |
| Alex Tuffour, Anthony Adebayiga Kosiba, Frank Addai Peprah, Jie Gu, Yang Zhou, Haifeng Sh. Cadmium-induced Stress: A Close Look at the Relationship between Autophagy and Apoptosis. Toxicological sciences : an official journal of the Society of Toxicology. 2023-05-11. PMID:37166467. |
this review therefore focuses on current trends in autophagy biomarkers, the effect of cd on the expression of lc3-ii, p62, vmp1, and beclin-1 and their relation and inter-regulatory roles in autophagy and apoptosis, pharmacological importance and the mechanisms involved. |
2023-05-11 |
2023-08-14 |
Not clear |
| Lixia Zhao, Ju Cheng, Di Liu, Hongxia Gong, Decheng Bai, Wei Su. Potentilla anserina polysaccharide alleviates cadmium-induced oxidative stress and apoptosis of H9c2 cells by regulating the MG53-mediated RISK pathway. Chinese journal of natural medicines. vol 21. issue 4. 2023-04-29. PMID:37120246. |
cd decreased the activities of sod and cat and the ratio of gsh/gssg, resulting in decreases in cell viability and increases in apoptosis. |
2023-04-29 |
2023-08-14 |
cat |
| Manal A Alfwuaires, Ademola C Famurewa, Abdulmohsen I Algefare, Azza Sedk. Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats. Drug and chemical toxicology. 2023-04-19. PMID:37073537. |
liver is one of the targets of cadmium (cd) bioaccumulation for hepatic damage and pathologies via oxidative inflammation and apoptosis. |
2023-04-19 |
2023-08-14 |
rat |
| Song Van Nguyen, Levar Shamoun, Kalle Landerholm, Dick Wågsäter, Jan Dimber. Clinicopathological and prognostic value of CD44 gene polymorphism (rs187115) in Swedish patients with colorectal cancer. Nucleosides, nucleotides & nucleic acids. 2023-04-19. PMID:37074032. |
cluster of differentiation (cd) 44 plays a crucial role in apoptosis, cell-cell interactions, angiogenesis, metastasis and proliferation. |
2023-04-19 |
2023-08-14 |
Not clear |