Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Lulu Ding, Huali Zhu, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Bianhua Zhou, Hongwei Wang, Zijun Yang, Zongping Liu, Jicang Wan. Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway. Environmental science and pollution research international. 2023-11-24. PMID:38001299. |
the results showed that compared with the control group, the cd treated group showed a significant decrease in cell viability (p < 0.01), an increase in intracellular ros levels, and apoptosis. |
2023-11-24 |
2023-11-28 |
rat |
Lulu Ding, Huali Zhu, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Bianhua Zhou, Hongwei Wang, Zijun Yang, Zongping Liu, Jicang Wan. Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway. Environmental science and pollution research international. 2023-11-24. PMID:38001299. |
compared with the cd treatment group, the cd and que co treatment group and the cd and 4-pba co treatment group showed a significant increase in cell viability (p < 0.01), a decrease in intracellular ros levels, a decrease in cell apoptosis, and a significant decrease in the expression levels of ers and apoptosis related factors mrna and protein (p < 0.01), as well as a significant increase in bcl-2 mrna and protein expression (p < 0.01). |
2023-11-24 |
2023-11-28 |
rat |
Lulu Ding, Huali Zhu, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Bianhua Zhou, Hongwei Wang, Zijun Yang, Zongping Liu, Jicang Wan. Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway. Environmental science and pollution research international. 2023-11-24. PMID:38001299. |
we confirmed that que could alleviate the apoptosis caused by cd in brl-3a cells, and the effects of que were similar to those of ers inhibitor. |
2023-11-24 |
2023-11-28 |
rat |
Chien-Yu Lin, Chi-Kang Wang, Fung-Chang Sung, Ta-Chen S. The Association among Urinary Lead and Cadmium, Serum Adiponectin, and Serum Apoptotic Microparticles in a Young Taiwanese Population. Nutrients. vol 15. issue 21. 2023-11-14. PMID:37960181. |
additionally, the role of adiponectin in the relationship between pb and cd exposure and vascular endothelial cell apoptosis has never been investigated. |
2023-11-14 |
2023-11-20 |
human |
Volkan Gelen, Emin Sengul, Serkan Yildirim, İrfan Cina. The role of GRP78/ATF6/IRE1 and caspase-3/Bax/Bcl2 signaling pathways in the protective effects of gallic acid against cadmium-induced liver damage in rats. Iranian journal of basic medical sciences. vol 26. issue 11. 2023-10-27. PMID:37886005. |
studies have shown that apoptosis, inflammation, and endoplasmic reticulum stress play a role in organ damage caused by cd. |
2023-10-27 |
2023-11-08 |
rat |
Mahdieh Raeeszadeh, Midia Moradian, Nadia Khademi, Ali Akbar Amir. The Effectiveness of Time in Treatment with Vitamin C and Broccoli Extract on Cadmium Poisoning in Mice: Histological Changes of Testicular Tissue and Cell Apoptotic Index. Biological trace element research. 2023-10-11. PMID:37821783. |
the apoptosis index in testicular tissue reached its highest level in the cd group and its lowest level in the cd + b300 and cd + vc groups during the fourth week (p < 0.05). |
2023-10-11 |
2023-10-15 |
mouse |
Milton Talukder, Shao-Shuai Bi, Mei-Wei Lv, Jing Ge, Cong Zhang, Jin-Long L. Involvement of the heat shock response (HSR) regulatory pathway in cadmium-elicited cerebral damage. Environmental science and pollution research international. 2023-09-21. PMID:37730984. |
furthermore, cd exposure increased tunel-positive neuronal apoptotic cells and up-regulated protein expression of caspase-1, caspase-8, caspase-3, and p53, leading to apoptosis. |
2023-09-21 |
2023-10-07 |
chicken |
Milton Talukder, Shao-Shuai Bi, Mei-Wei Lv, Jing Ge, Cong Zhang, Jin-Long L. Involvement of the heat shock response (HSR) regulatory pathway in cadmium-elicited cerebral damage. Environmental science and pollution research international. 2023-09-21. PMID:37730984. |
moreover, cd exposure activates caspase-1, caspase-8, caspase-3, and p53 protein, thereby resulting in neuronal apoptosis in the chicken brain. |
2023-09-21 |
2023-10-07 |
chicken |
Liliana Lykowska-Szuber, Michal Walczak, Kamila Stawczyk-Eder, Iwona Krela-Kazmierczak, Piotr Eder, Oliwia Zakerska-Banaszak, Agnieszka Dobrowolska, Marzena Skrzypczak-Zielinsk. Variants of the CASP9 gene as candidate markers for primary response to anti-TNF therapy in Crohn's disease patients. Journal of applied genetics. 2023-09-02. PMID:37658984. |
our results suggest that response to anti-tnf therapy in cd patients may be an effect of variants of the casp9 gene as a key effector of the internal pathway of apoptosis; however, further population and functional research are necessary. |
2023-09-02 |
2023-09-07 |
Not clear |
Renlin Yu, Zhubin Yang, Jiayu Liu, Haobo Bai, Hao Ding, Haofeng Xu, Hanbin Yu, Ju Cao, Xiaofei La. Absence of Toll-like Receptor 7 Ameliorates Survival and Reduces Intestinal Injury in Mice after Clostridium difficile Infection. Microbes and infection. 2023-08-27. PMID:37634661. |
in-vitro results have shown that tlr7 impairs the phagocytosis and killing ability of macrophages to cd, prompts reactive oxygen species (ros) production and accelerates apoptosis. |
2023-08-27 |
2023-09-07 |
mouse |
Liliana Lykowska-Szuber, Michal Walczak, Agnieszka Dobrowolska, Marzena Skrzypczak-Zielinsk. Apoptosis and inflammatory genes variants in primary non-response to anti-TNF therapy in Crohn's disease patients. European journal of gastroenterology & hepatology. 2023-08-14. PMID:37577818. |
in this article, we provide an overview of the current knowledge and findings in the pharmacogenetics of anti-tnf drugs in cd focusing on the aspect of apoptosis and inflammatory genes variants in primary non-response. |
2023-08-14 |
2023-08-16 |
Not clear |
Yanhong Li, Guiying Shi, Wei Liang, Haiquan Shang, Huiwu Li, Yunlin Han, Wenjie Zhao, Lin Bai, Chuan Qi. Allogeneic Adipose-Derived Mesenchymal Stem Cell Transplantation Alleviates Atherosclerotic Plaque by Inhibiting Ox-LDL Uptake, Inflammatory Reaction and Endothelial Damage in Rabbits. Cells. vol 12. issue 15. 2023-08-11. PMID:37566014. |
compared with the model group, blood lipid levels declined, the plaque area, oxidized low-density lipoprotein (ox-ldl) uptake, scavenger receptor a1 and cluster of differentiation (cd) 36 levels were all significantly reduced, and the accumulation of inflammatory m1 macrophages, apoptosis, interleukin (il)-6 and tumor necrosis factor (tnf)-α expression were decreased. |
2023-08-11 |
2023-08-16 |
rabbit |
Tingting Zhang, Siyuan Sun, Ana Gavrilović, Dapeng Li, Rong Tan. Selenium alleviates cadmium-induced oxidative stress, endoplasmic reticulum stress, and apoptosis in L8824 cells. Ecotoxicology and environmental safety. vol 262. 2023-08-11. PMID:37567109. |
cadmium (cd) is a toxic pollutant in industrial production that induces organ damage and apoptosis, while, selenium (se) has the biological function of antagonizing cd toxicity. |
2023-08-11 |
2023-08-16 |
cat |
Tingting Zhang, Siyuan Sun, Ana Gavrilović, Dapeng Li, Rong Tan. Selenium alleviates cadmium-induced oxidative stress, endoplasmic reticulum stress, and apoptosis in L8824 cells. Ecotoxicology and environmental safety. vol 262. 2023-08-11. PMID:37567109. |
the results showed that cd caused decreased cell viability, ros accumulation, reduced activity of antioxidant enzymes (sod, cat gpx and t-aoc) and apoptosis in l8824 cells. |
2023-08-11 |
2023-08-16 |
cat |
Tao Wang, Lianqi Yan, Li Wang, Jian Sun, Huayi Qu, Yonggang Ma, Ruilong Song, Xishuai Tong, Jiaqiao Zhu, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu, Hui Zo. VPS41-mediated incomplete autophagy aggravates cadmium-induced apoptosis in mouse hepatocytes. Journal of hazardous materials. vol 459. 2023-08-10. PMID:37562348. |
our data showed that cd triggered incomplete autophagy by downregulating vps41, aggravating cd-induced hepatocyte apoptosis. |
2023-08-10 |
2023-08-16 |
mouse |
Hang Liu, Xueyan Dai, Shiwen Xu, Huiling Guo, Jiamei Zhu, Sunan Wang, Yuning Wu, Caiying Zhan. Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium. The Science of the total environment. 2023-08-06. PMID:37544436. |
moreover, apoptosis rate obviously decreased in cd treated groups and clearly elevated in mo group. |
2023-08-06 |
2023-08-14 |
Not clear |
Hang Liu, Xueyan Dai, Shiwen Xu, Huiling Guo, Jiamei Zhu, Sunan Wang, Yuning Wu, Caiying Zhan. Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium. The Science of the total environment. 2023-08-06. PMID:37544436. |
mitochondria-mediated apoptosis was activated by excessive mo and inhibited by mo + cd, but cd exposure alone had little effect on it. |
2023-08-06 |
2023-08-14 |
Not clear |
Hang Liu, Xueyan Dai, Shiwen Xu, Huiling Guo, Jiamei Zhu, Sunan Wang, Yuning Wu, Caiying Zhan. Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium. The Science of the total environment. 2023-08-06. PMID:37544436. |
collectively, our research confirmed that mo and/or cd evoked necroptosis via nf-κb/tnf-α axis, and decreased death receptor-mediated apoptosis in duck myocardium, the impacts of mo and/or cd on mitochondrial-mediated apoptosis were different. |
2023-08-06 |
2023-08-14 |
Not clear |
Carolina N Ruera, Federico Perez, María Luz Iribarren, Luciana Guzman, Lorena Menendez, Laura Garbi, Fernando G Chird. Coexistence of apoptosis, pyroptosis, and necroptosis pathways in Celiac Disease. Clinical and experimental immunology. 2023-07-17. PMID:37455655. |
usually, the massive elimination of cells under steady-state conditions occurs by apoptosis, which is also acknowledged to explain the loss of enterocytes in the small intestine of celiac disease (cd) patients. |
2023-07-17 |
2023-08-14 |
Not clear |
Carolina N Ruera, Federico Perez, María Luz Iribarren, Luciana Guzman, Lorena Menendez, Laura Garbi, Fernando G Chird. Coexistence of apoptosis, pyroptosis, and necroptosis pathways in Celiac Disease. Clinical and experimental immunology. 2023-07-17. PMID:37455655. |
caspase-8 and caspase-3 expression was increased in cd, confirming the activation of apoptosis. |
2023-07-17 |
2023-08-14 |
Not clear |