| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fusen Yue, Jinsheng Xu, Linyi Meng, Qi Wang, Mingtao Tan, Aoying Zhang, Shanchun Yan, Dun Jian. A new insight into Cd exposure-induced hemocyte reduction in Lymantria dispar larvae: Involvement of the ROS-ATF6-ER stress-apoptosis pathway. Journal of hazardous materials. vol 469. 2024-03-20. PMID:38508113. |
the results showed that the number of larval hemocytes was significantly decreased under cd exposure, accompanied by a significant increase in the apoptosis rate and the expression of caspase-3. |
2024-03-20 |
2024-03-23 |
Not clear |
| Qingqing Li, Jing Li, Lixia Yin, Ju Huang, Xinyue Liu, Jinran Shi, Zhijun Geng, Xue Song, Lian Wang, Yueyue Wang, Xiaofeng Zhang, Lugen Zuo, Jianguo H. Sophoricoside improved Crohn's disease-like colitis by inhibiting intestinal epithelial cell apoptosis through PI3K/AKT signaling. International immunopharmacology. vol 131. 2024-03-17. PMID:38493691. |
increased apoptosis of intestinal epithelial cells (iecs) is a significant cause of intestinal barrier dysfunction in crohn's disease (cd). |
2024-03-17 |
2024-03-20 |
mouse |
| Danna Xie, Jun Yan, Honglong Zhang, Haijun Zhang, Guole Nie, Xingwang Zhu, Xun L. Cadmium exacerbates liver injury by remodeling ceramide metabolism: Multiomics and laboratory evidence. The Science of the total environment. 2024-03-03. PMID:38432385. |
in summary, cd increased ceramide levels by remodeling ceramide synthesis and catabolism, thereby promoting hepatocyte apoptosis and oxidative stress and ultimately aggravating liver injury. |
2024-03-03 |
2024-03-06 |
rat |
| Na Chen, Xiaoyan Wan, Mei Wang, Yamin Li, Xiaofei Wang, Ling Zeng, Jinzhao Zhou, Yanwei Zhang, Shun Cheng, Yi She. Cross-talk between Vimentin and autophagy regulates blood-testis barrier disruption induced by cadmium. Environmental pollution (Barking, Essex : 1987). 2024-02-24. PMID:38401636. |
we observed that cd can induce btb disruption, leading to apoptosis of testicular cells. |
2024-02-24 |
2024-02-27 |
Not clear |
| Na Chen, Xiaoyan Wan, Shun Cheng, Guiju Tang, Dan Xia, Yanling Xu, Yi She. Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis. Ecotoxicology and environmental safety. vol 273. 2024-02-17. PMID:38367604. |
we found that cd treatment caused a significant increase of apoptosis in scs cells, accompanied by a marked increase in the production of ros. |
2024-02-17 |
2024-02-20 |
Not clear |
| Na Chen, Xiaoyan Wan, Shun Cheng, Guiju Tang, Dan Xia, Yanling Xu, Yi She. Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis. Ecotoxicology and environmental safety. vol 273. 2024-02-17. PMID:38367604. |
together, this study provides insight into the negative effects of cd, which interferes with autophagic flux and induces the apoptosis of scs. |
2024-02-17 |
2024-02-20 |
Not clear |
| Zhonggui Gong, Wenjing Liu, Ruilong Song, Wenxuan Dong, Kanglei Zhang, Jiahui Li, Hui Zou, Jiaqiao Zhu, Yonggang Ma, Gang Liu, Zongping Li. Nuclear factor-kappaB mediates the survival of rat kidney cells after cadmium exposure via promoting autophagy and inhibiting apoptosis. Ecotoxicology and environmental safety. vol 249. 2024-02-07. PMID:38321684. |
in conclusion, cd exposure promotes the activation of nf-κb, and activated nf-κb mediates the survival of nrk-52e cells after cd exposure via promoting autophagy and inhibiting apoptosis. |
2024-02-07 |
2024-02-09 |
rat |
| Zili Lv, Jun Hu, Mingquan Huang, Guangrui Pan, Guofeng Xu, Meng Yan. Molecular mechanisms of cadmium-induced cytotoxicity in human ovarian granulosa cells identified using integrated omics. Ecotoxicology and environmental safety. vol 272. 2024-01-30. PMID:38290317. |
cd exposure was found to not only induce the apoptosis of the kgn cells but also further reduced mitochondrial function by decreasing mitochondrial membrane potential, atp production, and respiratory chain complex activity as well as increasing mitochondrial reactive oxygen species (ros) production. |
2024-01-30 |
2024-02-02 |
human |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
crohn's disease (cd) is a chronic relapsing inflammatory disorder in which defective apoptosis of mucosal t cells is postulated to produce sustained inflammation and reactive oxygen species accumulation. |
2024-01-22 |
2024-01-24 |
Not clear |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
whether cd t cells are intrinsically resistant to apoptosis or whether this resistance is acquired at the intestinal site needs to be clarified, as the cellular mechanisms modulate the impaired apoptosis in these cells. |
2024-01-22 |
2024-01-24 |
Not clear |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
the results showed that cd4 t cells from cd patients are less prone to apoptosis before they can migrate to the intestinal mucosa. |
2024-01-22 |
2024-01-24 |
Not clear |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
catalase activity was significantly reduced in cd t cells, which was confirmed in ex vivo experiments in which catalase inhibition in t cells from healthy controls triggered apoptosis inhibition in a dose-dependent manner. |
2024-01-22 |
2024-01-24 |
Not clear |
| Inés Moret-Tatay, Pilar Nos, Marisa Iborra, Francisco Rausell, Belén Beltrá. Catalase inhibition can modulate the ability of peripheral blood T cells to undergo apoptosis in Crohn's disease. Clinical and experimental immunology. 2024-01-22. PMID:38247555. |
in conclusion, apoptosis inhibition of cd t cells is a feature of these cells before they can migrate to the intestinal mucosa. |
2024-01-22 |
2024-01-24 |
Not clear |
| Shunli Che, Mengting Huang, Huiying Ma, Zhicheng Wan, Jianbin Feng, Shuquan Ding, Xilei L. Toxic effects of nanopolystyrene and cadmium on the intestinal tract of the Chinese mitten crab (Eriocheir sinensis). Ecotoxicology and environmental safety. vol 270. 2024-01-06. PMID:38183751. |
our results showed that ferroptosis, abc transporters, phosphotransferase system, apoptosis, and leukocyte transendothelial migration were disturbed after exposure to np and/or cd. |
2024-01-06 |
2024-01-09 |
Not clear |
| Mingkun Zhu, Ming Yan, Maierhaba Musa, Yurong Li, Yeshun Zhang, Xiaoting Zo. MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca Ecotoxicology and environmental safety. vol 269. 2024-01-04. PMID:38176135. |
microrna-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the mcu-mediated ca cadmium (cd) is known as a female reproductive toxicant. |
2024-01-04 |
2024-01-07 |
cat |
| Mingkun Zhu, Ming Yan, Maierhaba Musa, Yurong Li, Yeshun Zhang, Xiaoting Zo. MicroRNA-129-1-3p protects chicken granulosa cells from cadmium-induced apoptosis by down-regulating the MCU-mediated Ca Ecotoxicology and environmental safety. vol 269. 2024-01-04. PMID:38176135. |
our previous study has shown that cd can influence the proliferation and cell cycle of granulosa cells and induce apoptosis. |
2024-01-04 |
2024-01-07 |
cat |
| Daniil Romashin, Viktoriia Arzumanian, Ekaterina Poverennaya, Alexandra Varshaver, Nataliya Luzgina, Alexander Rusano. Evaluation of Cd-induced cytotoxicity in primary human keratinocytes. Human & experimental toxicology. vol 43. 2024-01-04. PMID:38174414. |
as in hacat cells, cd exposure resulted in increased ros levels, cell cycle arrest, and induction of apoptosis. |
2024-01-04 |
2024-01-06 |
human |
| Lulu Ding, Huali Zhu, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Bianhua Zhou, Hongwei Wang, Zijun Yang, Zongping Liu, Jicang Wan. Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway. Environmental science and pollution research international. 2023-11-24. PMID:38001299. |
previous studies have shown that que can alleviate cd caused hepatocyte apoptosis in rats, but the specific mechanism remains unclear. |
2023-11-24 |
2023-11-28 |
rat |
| Lulu Ding, Huali Zhu, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Bianhua Zhou, Hongwei Wang, Zijun Yang, Zongping Liu, Jicang Wan. Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway. Environmental science and pollution research international. 2023-11-24. PMID:38001299. |
the results showed that compared with the control group, the cd treated group showed a significant decrease in cell viability (p < 0.01), an increase in intracellular ros levels, and apoptosis. |
2023-11-24 |
2023-11-28 |
rat |
| Lulu Ding, Huali Zhu, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Bianhua Zhou, Hongwei Wang, Zijun Yang, Zongping Liu, Jicang Wan. Quercetin alleviates cadmium-induced BRL-3A cell apoptosis by inhibiting oxidative stress and the PERK/IRE1α/ATF6 signaling pathway. Environmental science and pollution research international. 2023-11-24. PMID:38001299. |
compared with the cd treatment group, the cd and que co treatment group and the cd and 4-pba co treatment group showed a significant increase in cell viability (p < 0.01), a decrease in intracellular ros levels, a decrease in cell apoptosis, and a significant decrease in the expression levels of ers and apoptosis related factors mrna and protein (p < 0.01), as well as a significant increase in bcl-2 mrna and protein expression (p < 0.01). |
2023-11-24 |
2023-11-28 |
rat |