| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melanie Beaujouin, Emmanuelle Liaudet-Coopma. Cathepsin D overexpressed by cancer cells can enhance apoptosis-dependent chemo-sensitivity independently of its catalytic activity. Advances in experimental medicine and biology. vol 617. 2008-07-10. PMID:18497069. |
both wt and mutated inactive cd are translocated to the cytosol, increasing the release of cytochrome c, the activation of caspases-9 and caspases-3 and the induction of a caspase-dependent apoptosis. |
2008-07-10 |
2023-08-12 |
Not clear |
| Qi T Yu, Masayuki Saruta, Konstantinos A Papadaki. Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways. Clinical immunology (Orlando, Fla.). vol 127. issue 3. 2008-07-07. PMID:18424236. |
visilizumab induced dose- and time-dependent apoptosis of lp t cells isolated from non-ibd individuals, uc or cd patients. |
2008-07-07 |
2023-08-12 |
Not clear |
| Neelima Pathak, Shashi Khandelwa. Impact of cadmium in T lymphocyte subsets and cytokine expression: differential regulation by oxidative stress and apoptosis. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 21. issue 2. 2008-07-01. PMID:17641822. |
oxidative stress and apoptosis appear to be underlying mechanism of cd induced thymic injury. |
2008-07-01 |
2023-08-12 |
mouse |
| Neelima Pathak, Shashi Khandelwa. Impact of cadmium in T lymphocyte subsets and cytokine expression: differential regulation by oxidative stress and apoptosis. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 21. issue 2. 2008-07-01. PMID:17641822. |
to understand the involvement of reactive oxygen species (ros), intracellular glutathione (gsh) and apoptosis in modulation of t-cell repertoire, we studied the effect of cd (10, 25 and 50 microm) on primary t lymphocytes of balb/c mice at different time intervals (6, 12 and 18 h). |
2008-07-01 |
2023-08-12 |
mouse |
| Neelima Pathak, Shashi Khandelwa. Impact of cadmium in T lymphocyte subsets and cytokine expression: differential regulation by oxidative stress and apoptosis. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 21. issue 2. 2008-07-01. PMID:17641822. |
in conclusion, our data demonstrates that t-cell apoptosis by cd, more in cd4(+)than in cd8(+)cells appear related to higher depletion of intracellular glutathione. |
2008-07-01 |
2023-08-12 |
mouse |
| Luís Cunha, André Amaral, Vera Medeiros, Gustavo M Martins, Francisco F M M Wallenstein, Ruben P Couto, Ana I Neto, Armindo Rodrigue. Bioavailable metals and cellular effects in the digestive gland of marine limpets living close to shallow water hydrothermal vents. Chemosphere. vol 71. issue 7. 2008-06-17. PMID:18166212. |
whole body concentrations of several metals (ca, cd, cs, co, cu, fe, hg, mg, mn, pb, rb, se, sr, and zn) were obtained, morphometry analysis of the digestive gland and tunel test for apoptosis were also performed. |
2008-06-17 |
2023-08-12 |
Not clear |
| Andreas Sturm, Heitor S P de Souza, Claudio Fiocch. Mucosal T cell proliferation and apoptosis in inflammatory bowel disease. Current drug targets. vol 9. issue 5. 2008-06-12. PMID:18473766. |
this article will review some of the basic features of human intestinal mucosal t cells, examine the mechanisms underlying the processes of cell cycling and cell death, describe the defective proliferative and apoptotic function detected in cd and uc, and discuss the implications of modulating t cell apoptosis in ibd for therapeutic purposes and eventually decreasing the risk of cancer development. |
2008-06-12 |
2023-08-12 |
human |
| Junny Chan, Elizabeth H Rabbitt, Barbara A Innes, Judith N Bulmer, Paul M Stewart, Mark D Kilby, Martin Hewiso. Glucocorticoid-induced apoptosis in human decidua: a novel role for 11beta-hydroxysteroid dehydrogenase in late gestation. The Journal of endocrinology. vol 195. issue 1. 2008-06-11. PMID:17911392. |
changes in decidual 11beta-hsd1 with gestation were paralleled by increased expression of the apoptosis markers caspase-3 and annexin-v, particularly in cluster designation (cd)10(-ve) non-stromal cells (20-fold in third trimester relative to first trimester). |
2008-06-11 |
2023-08-12 |
human |
| Soumya Chatterjee, Subhadip Kundu, Arindam Bhattacharyy. Mechanism of cadmium induced apoptosis in the immunocyte. Toxicology letters. vol 177. issue 2. 2008-06-06. PMID:18281164. |
it is well known that cadmium (cd) has toxic and carcinogenic effects in rhondents and humans, but the effects of cadmium on apoptosis are still not clear. |
2008-06-06 |
2023-08-12 |
mouse |
| Yves Nzengue, Régine Steiman, Pascale Guirau. Characterization of the cell death induced by cadmium in HaCaT and C6 cell lines. Free radical research. vol 42. issue 2. 2008-05-22. PMID:18297607. |
cell death resulting from cadmium (cd) intoxication has been confirmed to induce both necrosis and apoptosis. |
2008-05-22 |
2023-08-12 |
human |
| Yves Nzengue, Régine Steiman, Pascale Guirau. Characterization of the cell death induced by cadmium in HaCaT and C6 cell lines. Free radical research. vol 42. issue 2. 2008-05-22. PMID:18297607. |
at these concentrations, features of apoptosis were observed 24 h after c6 cell treatment: apoptotic dna fragmentation and caspase-9 activation, whereas cd did not induce caspase-3. |
2008-05-22 |
2023-08-12 |
human |
| Yves Nzengue, Régine Steiman, Pascale Guirau. Characterization of the cell death induced by cadmium in HaCaT and C6 cell lines. Free radical research. vol 42. issue 2. 2008-05-22. PMID:18297607. |
the results also showed that the inhibition of p53 led to a resistance of the c6 cells to 20 microm cd, decreased the apoptosis and increased the metallothioneins in these cells. |
2008-05-22 |
2023-08-12 |
human |
| Yves Nzengue, Régine Steiman, Pascale Guirau. Characterization of the cell death induced by cadmium in HaCaT and C6 cell lines. Free radical research. vol 42. issue 2. 2008-05-22. PMID:18297607. |
the results suggest that cd induced apoptosis in c6 cells but a non-apoptotic cellular death in hacat cells. |
2008-05-22 |
2023-08-12 |
human |
| Yi-Sook Jung, Euy-Myoung Jeong, Eun Kyung Park, You-Mie Kim, Seonghyang Sohn, Soo Hwan Lee, Eun Joo Baik, Chang-Hyun Moo. Cadmium induces apoptotic cell death through p38 MAPK in brain microvessel endothelial cells. European journal of pharmacology. vol 578. issue 1. 2008-05-06. PMID:17961543. |
the cell death induced by cd appeared to involve apoptosis, based on our results from annexin v staining, electron microscopy and tunel staining. |
2008-05-06 |
2023-08-12 |
mouse |
| Shunchang Wang, Minli Tang, Bei Pei, Xiang Xiao, Jun Wang, Haiying Hang, Lijun W. Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 2. 2008-04-10. PMID:17728284. |
the transition metal cadmium (cd) has been shown to induce apoptosis in a variety of cell lines and tissues. |
2008-04-10 |
2023-08-12 |
caenorhabditis_elegans |
| Shunchang Wang, Minli Tang, Bei Pei, Xiang Xiao, Jun Wang, Haiying Hang, Lijun W. Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 2. 2008-04-10. PMID:17728284. |
sublethal doses of cd exposure increased c. elegans germline apoptosis in a dose- and time-dependent manner. |
2008-04-10 |
2023-08-12 |
caenorhabditis_elegans |
| Shunchang Wang, Minli Tang, Bei Pei, Xiang Xiao, Jun Wang, Haiying Hang, Lijun W. Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways. Toxicological sciences : an official journal of the Society of Toxicology. vol 102. issue 2. 2008-04-10. PMID:17728284. |
the loss-of-function mutations of dna damage response (ddr) genes hus1 and p53 exhibited significant increase in germline apoptosis under cd exposure, and the depletion of p53 antagonist abl1 significantly enhanced apoptosis. |
2008-04-10 |
2023-08-12 |
caenorhabditis_elegans |
| Xiuli Lu, Fukushi Kambe, Xia Cao, Masako Yamauchi, Hisao Se. Insulin-like growth factor-I activation of Akt survival cascade in neuronal cells requires the presence of its cognate receptor in caveolae. Experimental cell research. vol 314. issue 2. 2008-03-05. PMID:18022157. |
igf-i treatment attenuated serum withdrawal-induced apoptosis, which was reversed by treatment with methyl-beta-cyclodextrin (cd) that removes cholesterol from plasma membrane. |
2008-03-05 |
2023-08-12 |
rat |
| Frank Thévenod, Natascha A Wolff, Ulrich Bork, Wing-Kee Lee, Marouan Abouhame. Cadmium induces nuclear translocation of beta-catenin and increases expression of c-myc and Abcb1a in kidney proximal tubule cells. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 20. issue 5. 2007-12-20. PMID:17136310. |
previously, we have demonstrated that cd(2+)-mediated up-regulation of the multidrug transporter abcb1 causes apoptosis resistance in pt cells. |
2007-12-20 |
2023-08-12 |
rat |
| U Hoffmann, K Heilmann, C Hayford, A Stallmach, U Wahnschaffe, M Zeitz, U Günthert, B M Witti. CD44v7 ligation downregulates the inflammatory immune response in Crohn's disease patients by apoptosis induction in mononuclear cells from the lamina propria. Cell death and differentiation. vol 14. issue 8. 2007-12-20. PMID:17479111. |
here we show that cd44v7 expression was upregulated upon cd40 ligation in human mononuclear cells, and examined whether ligation of cd44v7 also affects activation and apoptosis in lamina propria mononuclear cells (lpmc) from crohn's disease (cd) patients. |
2007-12-20 |
2023-08-12 |
human |