| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wing-Kee Lee, Malte Spielmann, Ulrich Bork, Frank Théveno. Cd2+-induced swelling-contraction dynamics in isolated kidney cortex mitochondria: role of Ca2+ uniporter, K+ cycling, and protonmotive force. American journal of physiology. Cell physiology. vol 289. issue 3. 2005-09-23. PMID:15843441. |
the nephrotoxic metal cd(2+) causes mitochondrial damage and apoptosis of kidney proximal tubule cells. |
2005-09-23 |
2023-08-12 |
rat |
| Nicolas Barnich, Jose E Aguirre, Hans-Christian Reinecker, Ramnik Xavier, Daniel K Podolsk. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition. The Journal of cell biology. vol 170. issue 1. 2005-09-21. PMID:15998797. |
nod2 associates with the caspase activation and recruitment domain of rip-like interacting caspase-like apoptosis regulatory protein kinase (rick)/rip2 and activates nuclear factor (nf)-kappab in epithelial cells and macrophages, whereas nod2 mutant 3020insc, which is associated with cd, shows an impaired ability to activate nf-kappab. |
2005-09-21 |
2023-08-12 |
Not clear |
| Craig D Albright, Kerry-Ann da Costa, Corneliu N Craciunescu, Erich Klem, Mei-Heng Mar, Steven H Zeise. Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 15. issue 1-4. 2005-08-04. PMID:15665516. |
previous studies show that acute choline deficiency (cd) triggers apoptosis in cultured rat hepatocytes (cwsv-1 cells). |
2005-08-04 |
2023-08-12 |
rat |
| Merja T Augustin, Jorma Kokkonen, Tuomo J Karttune. Evidence for increased apoptosis of duodenal intraepithelial lymphocytes in cow's milk sensitive enteropathy. Journal of pediatric gastroenterology and nutrition. vol 40. issue 3. 2005-07-14. PMID:15735492. |
enterocyte apoptosis induced by activated intraepithelial lymphocytes (iels) is increased in celiac disease (cd). |
2005-07-14 |
2023-08-12 |
Not clear |
| Riánsares Arriazu, José M Pozuelo, Rocío Martín, Rosario Rodríguez, Luis Santamarí. Quantitative and immunohistochemical evaluation of PCNA, androgen receptors, apoptosis, and Glutathione-S-Transferase P1 on preneoplastic changes induced by cadmium and zinc chloride in the rat ventral prostate. The Prostate. vol 63. issue 4. 2005-06-28. PMID:15602745. |
this study was directed to evaluate the immunoexpression of markers for cell proliferation, apoptosis, nuclear androgen receptors, and glutathione-s-transferase p1 (gstp1), in preneoplastic changes induced by cadmium chloride (cd) and cadmium plus zinc chloride (cd + zn) in rat prostate. |
2005-06-28 |
2023-08-12 |
rat |
| Elzbieta Bonda, Tadeusz Włostowski, Alicja Krasowsk. Testicular toxicity induced by dietary cadmium is associated with decreased testicular zinc and increased hepatic and renal metallothionein and zinc in the bank vole (Clethrionomys glareolus). Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 17. issue 6. 2005-05-19. PMID:15689104. |
dietary cd induced moderate histopathological changes (hemorrhage in interstitium, necrosis and apoptosis in seminiferous tubule epithelium) in young (1 month old) bank voles fed, for 6 weeks, fe-adequate (1.1-1.4 micromol/g) and fe-enriched (4.5-4.8 micromol/g) diets. |
2005-05-19 |
2023-08-12 |
Not clear |
| Francisco León, Laura Sánchez, Cristina Camarero, Garbiñe Ro. Cytokine production by intestinal intraepithelial lymphocyte subsets in celiac disease. Digestive diseases and sciences. vol 50. issue 3. 2005-05-04. PMID:15810648. |
iel subsets have a similar th1 profile in controls and cd patients, and the superior in vitro apoptosis of iels from cd patients may reflect their superior in vivo activation. |
2005-05-04 |
2023-08-12 |
human |
| Tapan K Mondal, Daming Li, Kamal Swami, J Kenneth Dean, Charles Hauer, David A Lawrenc. Mercury impairment of mouse thymocyte survival in vitro: involvement of cellular thiols. Journal of toxicology and environmental health. Part A. vol 68. issue 7. 2005-05-02. PMID:15805047. |
cadmium (cd) was the only other metal tested that also produced some significant level of dna loss; however, the induction of apoptosis by cd was not as consistent as that observed with hg. |
2005-05-02 |
2023-08-12 |
mouse |
| Wei-Xing Guo, Quentin N Pye, Kelly S Williamson, Charles A Stewart, Kenneth L Hensley, Yashige Kotake, Robert A Floyd, Robert H Broyle. Reactive oxygen species in choline deficiency-induced apoptosis in rat hepatocytes. Free radical biology & medicine. vol 37. issue 7. 2005-04-21. PMID:15336324. |
choline deficiency (cd) is involved in hepatocellular carcinoma and cd-induced apoptosis may be implicated in cellular malignant transformation. |
2005-04-21 |
2023-08-12 |
rat |
| F El Yafi, R Winkler, P Delvenne, N Boussif, J Belaiche, E Loui. Altered expression of type I insulin-like growth factor receptor in Crohn's disease. Clinical and experimental immunology. vol 139. issue 3. 2005-04-14. PMID:15730399. |
we aimed to describe igf-1r expression in cd intestinal lesions, to compare it to other intestinal inflammatory diseases and to correlate it with fibrosis and apoptosis. |
2005-04-14 |
2023-08-12 |
Not clear |
| F El Yafi, R Winkler, P Delvenne, N Boussif, J Belaiche, E Loui. Altered expression of type I insulin-like growth factor receptor in Crohn's disease. Clinical and experimental immunology. vol 139. issue 3. 2005-04-14. PMID:15730399. |
in cd submucosa, igf-1r expression in ic was inversely correlated with apoptosis in uninvolved areas (p = 0.01). |
2005-04-14 |
2023-08-12 |
Not clear |
| Yoshihiro Fukuda, Toshiyuki Matsui, Yasuo Suzuki, Kazunari Kanke, Takayuki Matsumoto, Masakazu Takazoe, Takayuki Matsumoto, Satoshi Motoya, Terasu Honma, Koji Sawada, Tsuneyoshi Yao, Takashi Shimoyama, Toshifumi Hib. Adsorptive granulocyte and monocyte apheresis for refractory Crohn's disease: an open multicenter prospective study. Journal of gastroenterology. vol 39. issue 12. 2005-04-05. PMID:15622479. |
active crohn's disease (cd) is often associated with elevated levels of platelets, granulocytes, and monocytes that are activated and resistant to apoptosis. |
2005-04-05 |
2023-08-12 |
Not clear |
| Sun Don Kim, Chang Kyu Moon, Su-Yong Eun, Pan Dong Ryu, Sangmee Ahn J. Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis. Biochemical and biophysical research communications. vol 328. issue 1. 2005-03-28. PMID:15670787. |
cd induces oxidative stress and apoptosis in various cells by activating mitogen-activated protein kinases (mapks), but the precise signaling components of the mapk cascade and their role in neuronal apoptosis are still unclear. |
2005-03-28 |
2023-08-12 |
Not clear |
| Sun Don Kim, Chang Kyu Moon, Su-Yong Eun, Pan Dong Ryu, Sangmee Ahn J. Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis. Biochemical and biophysical research communications. vol 328. issue 1. 2005-03-28. PMID:15670787. |
here, we report that cd treatment of sh-sy5y cells caused apoptosis through sequential phosphorylation of the apoptosis signal regulating kinase 1, mapk kinase 4, c-jun n-terminal kinase (jnk), and c-jun as determined by overexpression of dominant negative (dn) constructs of these genes or using a specific jnk inhibitor sp600125. |
2005-03-28 |
2023-08-12 |
Not clear |
| Sun Don Kim, Chang Kyu Moon, Su-Yong Eun, Pan Dong Ryu, Sangmee Ahn J. Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis. Biochemical and biophysical research communications. vol 328. issue 1. 2005-03-28. PMID:15670787. |
in addition, caspase inhibitors, zdevd and zvad, reduced apoptosis but not jnk and c-jun phosphorylation induced by cd, while overexpression of dn jnk1 inhibited caspase-3 activity. |
2005-03-28 |
2023-08-12 |
Not clear |
| Wing-Kee Lee, Ulrich Bork, Fatemeh Gholamrezaei, Frank Théveno. Cd(2+)-induced cytochrome c release in apoptotic proximal tubule cells: role of mitochondrial permeability transition pore and Ca(2+) uniporter. American journal of physiology. Renal physiology. vol 288. issue 1. 2005-03-04. PMID:15339793. |
cd(2+) induces apoptosis of kidney proximal tubule (pt) cells. |
2005-03-04 |
2023-08-12 |
rat |
| Wing-Kee Lee, Ulrich Bork, Fatemeh Gholamrezaei, Frank Théveno. Cd(2+)-induced cytochrome c release in apoptotic proximal tubule cells: role of mitochondrial permeability transition pore and Ca(2+) uniporter. American journal of physiology. Renal physiology. vol 288. issue 1. 2005-03-04. PMID:15339793. |
mitochondria play a pivotal role in toxic compound-induced apoptosis by releasing cytochrome c. our objective was to investigate the mechanisms underlying cd(2+)-induced cytochrome c release from mitochondria in rat pt cells. |
2005-03-04 |
2023-08-12 |
rat |
| Wing-Kee Lee, Ulrich Bork, Fatemeh Gholamrezaei, Frank Théveno. Cd(2+)-induced cytochrome c release in apoptotic proximal tubule cells: role of mitochondrial permeability transition pore and Ca(2+) uniporter. American journal of physiology. Renal physiology. vol 288. issue 1. 2005-03-04. PMID:15339793. |
using hoechst 33342 or mtt assay, 10 mum cd(2+) induced approximately 5-10% apoptosis in pt cells at 6 and 24 h, which was associated with cytochrome c and apoptosis-inducing factor release at 24 h only. |
2005-03-04 |
2023-08-12 |
rat |
| Herma Fidder, Yehuda Chowers, Zvi Ackerman, Rivka Dresner Pollak, J Bart A Crusius, Avi Livneh, Simon Bar-Meir, Benjamin Avidan, Yael Shinha. The familial Mediterranean fever (MEVF) gene as a modifier of Crohn's disease. The American journal of gastroenterology. vol 100. issue 2. 2005-03-01. PMID:15667491. |
interestingly, functional similarities between the cd susceptibility gene (nod2/card15) and the fmf gene (mefv) have been described: both belong to the death domain containing protein family, important in the regulation of apoptosis, cytokine processing and inflammation. |
2005-03-01 |
2023-08-12 |
Not clear |
| Mihaela Ringheanu, Fredric Daum, James Markowitz, Jeremiah Levine, Seymour Katz, Xingyu Lin, Jack Silve. Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease. Inflammatory bowel diseases. vol 10. issue 6. 2005-01-31. PMID:15626899. |
infliximab, an anti-tumor necrosis factor (tnf) monoclonal antibody, might exert some of its long-term therapeutic effects in crohn's disease (cd) by interacting directly with cells of the immune system such as monocytes and t lymphocytes via membrane tnf and by inducing apoptosis. |
2005-01-31 |
2023-08-12 |
Not clear |