| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saïd Nemmiche, Daoudi Chabane-Sari, Malika Kadri, Pascale Guirau. Cadmium-induced apoptosis in the BJAB human B cell line: involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression. Toxicology. vol 300. issue 3. 2012-10-05. PMID:22659318. |
the objective of the present study was to investigate the mechanism of ho-1 induction during cadmium (cd)-induced oxidative stress and apoptosis in the lymphocyte b cell line bjab. |
2012-10-05 |
2023-08-12 |
human |
| Saïd Nemmiche, Daoudi Chabane-Sari, Malika Kadri, Pascale Guirau. Cadmium-induced apoptosis in the BJAB human B cell line: involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression. Toxicology. vol 300. issue 3. 2012-10-05. PMID:22659318. |
increased dna fragmentation and caspase-3 activity were observed in bjab cells exposed to 5-40 μm cdcl(2) revealing that cd induced apoptosis in these cells. |
2012-10-05 |
2023-08-12 |
human |
| Aneta Salińska, Tadeusz Włostowski, Sebastian Maciak, Barbara Łaszkiewicz-Tiszczenko, Paweł Kozłowsk. Combined effect of dietary cadmium and benzo(a)pyrene on metallothionein induction and apoptosis in the liver and kidneys of bank voles. Biological trace element research. vol 147. issue 1-3. 2012-10-03. PMID:22124863. |
at the end of exposure period, apoptosis and analyses of mt, cd, and zinc (zn) in the liver and kidneys were carried out. |
2012-10-03 |
2023-08-12 |
Not clear |
| Aneta Salińska, Tadeusz Włostowski, Sebastian Maciak, Barbara Łaszkiewicz-Tiszczenko, Paweł Kozłowsk. Combined effect of dietary cadmium and benzo(a)pyrene on metallothionein induction and apoptosis in the liver and kidneys of bank voles. Biological trace element research. vol 147. issue 1-3. 2012-10-03. PMID:22124863. |
dietary bap 5 μg/g did not affect but bap 10 μg/g potentiated rather than inhibited induction of hepatic and renal mt by cd, and diminished cd-induced apoptosis in both organs. |
2012-10-03 |
2023-08-12 |
Not clear |
| Halina Falfushynska, Lesya Gnatyshyna, Oksana Stoliar, Natalia Mitina, Taras Skorokhoda, Yevhen Filyak, Alexander Zaichenko, Rostyslav Stoik. Evaluation of biotargeting and ecotoxicity of Co²⁺-containing nanoscale polymeric complex by applying multi-marker approach in bivalve mollusk Anodonta cygnea. Chemosphere. vol 88. issue 8. 2012-10-03. PMID:22464855. |
on the other hand, co(2+) increased metal (co, cu, zn and cd) binding to mt (mt-me) without changes in mt-sh level jointly with activation of oxyradical formation and apoptosis and decreasing of lysosomal membrane stability. |
2012-10-03 |
2023-08-12 |
Not clear |
| Mohamed M Ghanem, Lori A Battelli, Brandon F Law, Vincent Castranova, Michael L Kashon, Joginder Nath, Ann F Hubb. Coal dust alters beta-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells. Particle and fibre toxicology. vol 6. 2012-10-02. PMID:19650907. |
in the cd and pah-exposed lung, cd increases apoptosis and causes alveolar type ii (at-ii) cell hyperplasia but reduces cyp1a1 induction. |
2012-10-02 |
2023-08-12 |
rat |
| Wing-Kee Lee, Ulrich Bork, Frank Théveno. Mitochondria as a target of cadmium nephrotoxicity: induction of swelling and cytochrome C release. Toxicology mechanisms and methods. vol 14. issue 1-2. 2012-10-02. PMID:20021126. |
cadmium (cd) is a potent environmental toxic compound that damages the kidney by inducing apoptosis of the proximal tubule cells. |
2012-10-02 |
2023-08-12 |
rat |
| Yasuo Oyama, Tomohiro Arata, Lumi Chikahisa, Fumio Soeda, Kazuo Takaham. Estimation of increased concentration of intracellular Cd(2+) by fluo-3 in rat thymocytes exposed to CdCl(2). Environmental toxicology and pharmacology. vol 11. issue 2. 2012-10-02. PMID:21782592. |
to reveal the mechanism of cadmium-induced apoptosis, one of important questions is whether cadmium increases intracellular concentration of ca(2+) ([ca(2+)](i)), cd(2+) ([cd(2+)](i)) or both. |
2012-10-02 |
2023-08-12 |
rat |
| Chao Zhang, Xia Yuan, Weiping Mao, Ling Yue, Xiuqin Kong, Yanhong Gao, Lan Luo, Zhimin Yi. Inhibition of cadmium-induced apoptosis by glutathione S-transferase P1 via mitogen-activated protein kinases and mitochondrial pathways. Environmental toxicology and pharmacology. vol 30. issue 2. 2012-10-02. PMID:21787653. |
overexpression of gstp1 inhibited loss of mitochondrial membrane potential, prevented cytochrome c release from mitochondria and caspase-3 activation, inhibited mitogen-activated protein kinases (mapks) including erk, jnk and p38, and suppressed apoptosis induced by cd(2+). |
2012-10-02 |
2023-08-12 |
human |
| Chao Zhang, Xia Yuan, Weiping Mao, Ling Yue, Xiuqin Kong, Yanhong Gao, Lan Luo, Zhimin Yi. Inhibition of cadmium-induced apoptosis by glutathione S-transferase P1 via mitogen-activated protein kinases and mitochondrial pathways. Environmental toxicology and pharmacology. vol 30. issue 2. 2012-10-02. PMID:21787653. |
the oligonucleosomal dna fragmentation assay also demonstrated that overexpression of gstp1 by adenovirus infection prevented cd(2+)-induced apoptosis in primary renal tubule cells. |
2012-10-02 |
2023-08-12 |
human |
| Chao Zhang, Xia Yuan, Weiping Mao, Ling Yue, Xiuqin Kong, Yanhong Gao, Lan Luo, Zhimin Yi. Inhibition of cadmium-induced apoptosis by glutathione S-transferase P1 via mitogen-activated protein kinases and mitochondrial pathways. Environmental toxicology and pharmacology. vol 30. issue 2. 2012-10-02. PMID:21787653. |
our data suggest that gstp1 was an endogenous inhibitor of cd(2+)-induced apoptosis. |
2012-10-02 |
2023-08-12 |
human |
| Shuhua Yang, Ziwei Zhang, Jianbin He, Jinlong Li, Jiuli Zhang, Houjuan Xing, Shiwen X. Ovarian toxicity induced by dietary cadmium in hen. Biological trace element research. vol 148. issue 1. 2012-10-02. PMID:22367677. |
it indicated that cd exposure resulted in oxidative damage of hens' ovary tissue by altering antioxidant defense enzyme systems, lipid peroxidation, apoptosis and endocrine disturbance which may be possible underlying reproductive toxicity mechanisms induced by cd. |
2012-10-02 |
2023-08-12 |
Not clear |
| Jordan Clark, Rania Nasrallah, Richard L Héber. The PPARδ ligand GW501516 reduces growth but not apoptosis in mouse inner medullary collecting duct cells. PPAR research. vol 2009. 2012-09-25. PMID:19266055. |
while its role is unknown in the cd, in other renal cells it has been shown to regulate both growth and apoptosis. |
2012-09-25 |
2023-08-12 |
mouse |
| Barbara Messner, Christian Ploner, Günther Laufer, David Bernhar. Cadmium activates a programmed, lysosomal membrane permeabilization-dependent necrosis pathway. Toxicology letters. vol 212. issue 3. 2012-09-25. PMID:22677345. |
in past studies cd was shown to cause apoptosis, necrosis, programmed necrosis, or autophagy. |
2012-09-25 |
2023-08-12 |
Not clear |
| Martin Steinkamp, Nadine Schulte, Ulrike Spaniol, Carolin Pflüger, Christoph Hartmann, Joachim Kirsch, Georg B von Boye. Brain derived neurotrophic factor inhibits apoptosis in enteric glia during gut inflammation. Medical science monitor : international medical journal of experimental and clinical research. vol 18. issue 4. 2012-08-07. PMID:22460084. |
as a diminished egc network is postulated in crohn's disease (cd), we aimed to investigate if egcs could be a target of apoptosis during inflammation in cd, which can be influenced by brain derived neurotrophic factor (bdnf). |
2012-08-07 |
2023-08-12 |
Not clear |
| Dongmei Liu, Bo Yan, Jian Yang, Wenwen Lei, Lan Wan. Mitochondrial pathway of apoptosis in the hepatopancreas of the freshwater crab Sinopotamon yangtsekiense exposed to cadmium. Aquatic toxicology (Amsterdam, Netherlands). vol 105. issue 3-4. 2012-07-27. PMID:21831345. |
to investigate the mechanism of cd-induced apoptosis in the hepatopancreas, freshwater crabs sinopotamon yangtsekiense were exposed to 0, 3.56, 7.12, 14.25, 28.49 and 56.98 mg/l cd for 48 h. after a 48 h exposure, apoptosis and necroptosis were apparent in the group exposed to 28.49 mg/l cd and only one case of necrosis was observed in the highest concentration of cd. |
2012-07-27 |
2023-08-12 |
Not clear |
| Dongmei Liu, Bo Yan, Jian Yang, Wenwen Lei, Lan Wan. Mitochondrial pathway of apoptosis in the hepatopancreas of the freshwater crab Sinopotamon yangtsekiense exposed to cadmium. Aquatic toxicology (Amsterdam, Netherlands). vol 105. issue 3-4. 2012-07-27. PMID:21831345. |
these results implied that cd induced apoptosis in the hepatopancreas occurs through a mitochondrial pathway. |
2012-07-27 |
2023-08-12 |
Not clear |
| Tuomo S Kokkonen, Merja T Augustin, Jorma Kokkonen, Riitta Karttunen, Tuomo J Karttune. Serum and tissue CD23, IL-15, and FasL in cow's-milk protein-sensitive enteropathy and in coeliac disease. Journal of pediatric gastroenterology and nutrition. vol 54. issue 4. 2012-07-16. PMID:21946835. |
we also presumed that interleukin (il)-15 and fasl, functionally connected with proliferation and apoptosis of the intraepithelial lymphocytes (iels), would relate with the increased numbers of iels present in both cmse and cd. |
2012-07-16 |
2023-08-12 |
Not clear |
| Vikram Sabapathy, Saranya Ravi, Vivi Srivastava, Alok Srivastava, Sanjay Kuma. Long-term cultured human term placenta-derived mesenchymal stem cells of maternal origin displays plasticity. Stem cells international. vol 2012. 2012-07-13. PMID:22550499. |
these cells did not significantly alter cell cycle or apoptosis pattern while maintaining the normal karyotype; they also have limited expression of mhc-ii antigens and are naive for stimulatory factors cd80 and cd 86. |
2012-07-13 |
2023-08-12 |
human |
| Martin Steinkamp, Heike Gundel, Nadine Schulte, Ulrike Spaniol, Carolin Pflueger, Eugen Zizer, Georg B T von Boye. GDNF protects enteric glia from apoptosis: evidence for an autocrine loop. BMC gastroenterology. vol 12. 2012-07-02. PMID:22251670. |
during the course of acute crohn's disease (cd), mucosal egc progressively undergo apoptosis, though the mechanisms are largely unknown. |
2012-07-02 |
2023-08-12 |
Not clear |