| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neelima Pathak, Sumonto Mitra, Shashi Khandelwa. Cadmium induces thymocyte apoptosis via caspase-dependent and caspase-independent pathways. Journal of biochemical and molecular toxicology. vol 27. issue 3. 2013-09-23. PMID:23315796. |
intracellular ca²⁺ and reactive oxygen species (ros) levels significantly raised by cd were restored by ruthenium red, which had no influence on mitochondrial membrane depolarization and caspase activity and apoptosis. |
2013-09-23 |
2023-08-12 |
Not clear |
| Yan-Li Ji, Hua Wang, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, De-Xiang X. N-acetylcysteine protects against cadmium-induced germ cell apoptosis by inhibiting endoplasmic reticulum stress in testes. Asian journal of andrology. vol 15. issue 2. 2013-09-18. PMID:23353715. |
cadmium (cd) is a reproductive toxicant that induces germ cell apoptosis in the testes. |
2013-09-18 |
2023-08-12 |
mouse |
| Yan-Li Ji, Hua Wang, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, De-Xiang X. N-acetylcysteine protects against cadmium-induced germ cell apoptosis by inhibiting endoplasmic reticulum stress in testes. Asian journal of andrology. vol 15. issue 2. 2013-09-18. PMID:23353715. |
as expected, acute cd exposure induced germ cell apoptosis in the testes, as determined by terminal dutp nick-end labelling (tunel). |
2013-09-18 |
2023-08-12 |
mouse |
| Dongmei Liu, Jian Yang, Lan Wan. Cadmium induces ultrastructural changes in the hepatopancreas of the freshwater crab Sinopotamon henanense. Micron (Oxford, England : 1993). vol 47. 2013-09-16. PMID:23402952. |
apoptosis was the notable cell damage induced by cd and presumed to be ascribed to various organelle injuries. |
2013-09-16 |
2023-08-12 |
Not clear |
| Su-Jin Kim, Jae-Young Um, Sung-Hoon Kim, Seung-Heon Hon. Protective effect of rosmarinic acid is through regulation of inflammatory cytokine in cadmium-induced ototoxicity. The American journal of Chinese medicine. vol 41. issue 2. 2013-09-09. PMID:23548128. |
the findings showed that ra inhibited cd(2+) -mediated cell toxicity, reactive oxygen species generation, interleukin (il)-6 and il-1β production, the translocation of the apoptosis inducing factor into the nucleus and activation of caspases-3 in an auditory cell line, hei-oc1. |
2013-09-09 |
2023-08-12 |
rat |
| Savvas Petanidis, Margarita Hadzopoulou-Cladaras, Athanasios Salifoglo. Cadmium modulates H-ras expression and caspase-3 apoptotic cell death in breast cancer epithelial MCF-7 cells. Journal of inorganic biochemistry. vol 121. 2013-08-23. PMID:23376331. |
given the biotoxicity of cadmium and its association with carcinogenesis, the effect of that metal ion (cd(ii)) was investigated, in a concentration-dependent fashion, on cell viability, cell proliferation, caspase-3 mediated apoptosis and h-ras gene expression in human breast cancer epithelial mcf-7 cells transfected with the h-ras oncogene (wild type and g12v mutation). |
2013-08-23 |
2023-08-12 |
human |
| B E Grôsvik, A Goksôy. Biomarker protein expression in primary cultures of salmon (Salmo salar L.) hepatocytes exposed to environmental pollutants. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. vol 1. issue 1. 2013-07-30. PMID:23888893. |
the hepatocytes showed cytoplasmic protrusions after treatment with 35 μm arsenite and 100 μm cd, indicative of cells entering apoptosis. |
2013-07-30 |
2023-08-12 |
Not clear |
| Douglas M Templeton, Ying Li. Effects of cadmium on the actin cytoskeleton in renal mesangial cells. Canadian journal of physiology and pharmacology. vol 91. issue 1. 2013-07-12. PMID:23368511. |
we provide an overview of our studies on cadmium and the actin cytoskeleton in mesangial cells, from earlier work on the effects of cd(2+) on actin polymerization in vivo and in vitro, to a role of disruption or stabilization of the cytoskeleton in apoptosis and apoptosis-like death. |
2013-07-12 |
2023-08-12 |
mouse |
| Hirotomo Yamada, Rie Uenishi, Kaoru Suzuki, Shinji Koizum. Cadmium-induced alterations of gene expression in human cells. Environmental toxicology and pharmacology. vol 28. issue 1. 2013-07-04. PMID:21783983. |
cd also affected a number of genes related to apoptosis. |
2013-07-04 |
2023-08-12 |
human |
| Hirotomo Yamada, Rie Uenishi, Kaoru Suzuki, Shinji Koizum. Cadmium-induced alterations of gene expression in human cells. Environmental toxicology and pharmacology. vol 28. issue 1. 2013-07-04. PMID:21783983. |
the present study disclosed a complex pleiotypic response of human cells to cd, which was composed of a variety of changes in gene expression directed to defense, growth arrest, recovery from damage, apoptosis and so on. |
2013-07-04 |
2023-08-12 |
human |
| Nabilah Muhammad Nadzri, Ahmad Bustamam Abdul, Mohd Aspollah Sukari, Siddig Ibrahim Abdelwahab, Eltayeb E M Eid, Syam Mohan, Behnam Kamalidehghan, Theebaa Anasamy, Kuan Beng Ng, Suvitha Syam, Ismail Adam Arbab, Heshu Sulaiman Rahman, Hapipah Mohd Al. Inclusion Complex of Zerumbone with Hydroxypropyl- β -Cyclodextrin Induces Apoptosis in Liver Hepatocellular HepG2 Cells via Caspase 8/BID Cleavage Switch and Modulating Bcl2/Bax Ratio. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-07-04. PMID:23737847. |
the anticancer effects of this new zer-hp β cd inclusion complex via apoptosis cell death were assessed in this study for the first time in liver hepatocellular cells, hepg2. |
2013-07-04 |
2023-08-12 |
human |
| Asit Rai, Shailendra Kumar Maurya, Rolee Sharma, Shakir Al. Down-regulated GFAPα: a major player in heavy metal induced astrocyte damage. Toxicology mechanisms and methods. vol 23. issue 2. 2013-07-02. PMID:22901236. |
exposure to a mixture of as, pb and cd induces apoptosis and morphological alterations in the cortical astrocytes of rat brain. |
2013-07-02 |
2023-08-12 |
rat |
| Stefanie Derer, Andreas Till, Robert Haesler, Christian Sina, Nils Grabe, Sascha Jung, Susanna Nikolaus, Tanja Kuehbacher, Joachim Groetzinger, Stefan Rose-John, Philip C Rosenstiel, Stefan Schreibe. mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease. Gut. vol 62. issue 3. 2013-04-09. PMID:22535372. |
mechanisms of action (moa) of anti-tumour necrosis factor α (tnfα) therapies in crohn's disease (cd) may critically involve induction of immune cell apoptosis via membrane-bound tnfα (mtnfα) binding. |
2013-04-09 |
2023-08-12 |
Not clear |
| Stefanie Derer, Andreas Till, Robert Haesler, Christian Sina, Nils Grabe, Sascha Jung, Susanna Nikolaus, Tanja Kuehbacher, Joachim Groetzinger, Stefan Rose-John, Philip C Rosenstiel, Stefan Schreibe. mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease. Gut. vol 62. issue 3. 2013-04-09. PMID:22535372. |
certolizumab pegol (czp), which is effective in induction and maintenance of remission in cd lacks the ability to induce apoptosis. |
2013-04-09 |
2023-08-12 |
Not clear |
| Jinxiang Wang, Qian Wang, Jiarui Li, Qingqing Shen, Fei Wang, Lan Wan. Cadmium induces hydrogen peroxide production and initiates hydrogen peroxide-dependent apoptosis in the gill of freshwater crab, Sinopotamon henanense. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 156. issue 3-4. 2013-02-07. PMID:22692000. |
cd has been reported to induce oxidative damage and apoptosis. |
2013-02-07 |
2023-08-12 |
Not clear |
| Jinxiang Wang, Qian Wang, Jiarui Li, Qingqing Shen, Fei Wang, Lan Wan. Cadmium induces hydrogen peroxide production and initiates hydrogen peroxide-dependent apoptosis in the gill of freshwater crab, Sinopotamon henanense. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 156. issue 3-4. 2013-02-07. PMID:22692000. |
we show that in the gills of the freshwater crab sinopotamon henanense cd induced apoptosis, in a time- and concentration-dependent manner, as confirmed by dna fragmentation analysis and transmission electron microscopy. |
2013-02-07 |
2023-08-12 |
Not clear |
| Yan-Li Ji, Zhen Wang, Hua Wang, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, Xiu-Hong Meng, De-Xiang X. Ascorbic acid protects against cadmium-induced endoplasmic reticulum stress and germ cell apoptosis in testes. Reproductive toxicology (Elmsford, N.Y.). vol 34. issue 3. 2013-01-24. PMID:22569276. |
cadmium (cd) is a testicular toxicant which induces endoplasmic reticulum (er) stress and germ cell apoptosis in testes. |
2013-01-24 |
2023-08-12 |
mouse |
| Yan-Li Ji, Zhen Wang, Hua Wang, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, Xiu-Hong Meng, De-Xiang X. Ascorbic acid protects against cadmium-induced endoplasmic reticulum stress and germ cell apoptosis in testes. Reproductive toxicology (Elmsford, N.Y.). vol 34. issue 3. 2013-01-24. PMID:22569276. |
as expected, a single dose of cd induced testicular germ cell apoptosis. |
2013-01-24 |
2023-08-12 |
mouse |
| Evelien Rozema, Ruxandra Popescu, Harald Sonderegger, Christian W Huck, Johannes Winkler, Georg Krupitza, Ernst Urban, Brigitte Kop. Characterization of glucocerebrosides and the active metabolite 4,8-sphingadienine from Arisaema amurense and Pinellia ternata by NMR and CD spectroscopy and ESI-MS/CID-MS. Journal of agricultural and food chemistry. vol 60. issue 29. 2012-11-21. PMID:22769731. |
characterization of glucocerebrosides and the active metabolite 4,8-sphingadienine from arisaema amurense and pinellia ternata by nmr and cd spectroscopy and esi-ms/cid-ms. sphingolipid metabolites regulate cellular processes such as cell proliferation, differentiation, and apoptosis. |
2012-11-21 |
2023-08-12 |
Not clear |
| R Chandra, S K Dass, P Tomar, M Tiwar. Cadmium, carcinogen, co-carcinogen and anti carcinogen. Indian journal of clinical biochemistry : IJCB. vol 16. issue 2. 2012-10-30. PMID:23105310. |
as a stress agent, inducing apoptosis and blocking it, cd can have both helpful and harmful effects. |
2012-10-30 |
2023-08-12 |
Not clear |