| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dian Gao, Zhen'e Xu, Panpan Qiao, Shen Liu, Li Zhang, Penghui He, Xiaoyan Zhang, Yannan Wang, Weiping Mi. Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio). PloS one. vol 8. issue 12. 2014-09-29. PMID:24349509. |
to assess whether caspase-3a is involved in cadmium (cd)-induced cell apoptosis in common carp, a cd exposure experiment was performed. |
2014-09-29 |
2023-08-12 |
human |
| Dian Gao, Zhen'e Xu, Panpan Qiao, Shen Liu, Li Zhang, Penghui He, Xiaoyan Zhang, Yannan Wang, Weiping Mi. Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio). PloS one. vol 8. issue 12. 2014-09-29. PMID:24349509. |
tunel analysis showed that cd triggered liver cell apoptosis; caspase-3a activity was markedly increased; its proenzyme level was significantly decreased, and the levels of its cleaved forms were markedly increased. |
2014-09-29 |
2023-08-12 |
human |
| Dian Gao, Zhen'e Xu, Panpan Qiao, Shen Liu, Li Zhang, Penghui He, Xiaoyan Zhang, Yannan Wang, Weiping Mi. Cadmium induces liver cell apoptosis through caspase-3A activation in purse red common carp (Cyprinus carpio). PloS one. vol 8. issue 12. 2014-09-29. PMID:24349509. |
the findings indicates that cd can trigger liver cell apoptosis through the activation of caspase-3a. |
2014-09-29 |
2023-08-12 |
human |
| Chia-Lei Lin, Lyda Williams, Yoshinori Seki, Harpreet Kaur, Kirsten Hartil, Ariana Fiallo, A Scott Glenn, Ellen B Katz, Maureen J Charron, Patricia M Vugui. Effects of genetics and in utero diet on murine pancreatic development. The Journal of endocrinology. vol 222. issue 2. 2014-09-05. PMID:24895417. |
compared with g4+/- cd, g4+/- hfd fetuses had increased pancreatic gene expression of igf2, a mitogen and inhibitor of apoptosis. |
2014-09-05 |
2023-08-13 |
mouse |
| A Rai, S Tripathi, R Kushwaha, P Singh, P Srivastava, S Sanyal, S Bandyopadhya. CDK5-induced p-PPARγ(Ser 112) downregulates GFAP via PPREs in developing rat brain: effect of metal mixture and troglitazone in astrocytes. Cell death & disease. vol 5. 2014-09-02. PMID:24481447. |
here, we investigated the role of pparγ in regulating gfap using a mixture of as, cd and pb (metal mixture, mm) that induces apoptosis and aberrant morphology in rat brain astrocytes. |
2014-09-02 |
2023-08-12 |
rat |
| Krishnendu Sinha, Pabitra Bikash Pal, Parames C Si. Cadmium (Cd(2+)) exposure differentially elicits both cell proliferation and cell death related responses in SK-RC-45. Toxicology in vitro : an international journal published in association with BIBRA. vol 28. issue 2. 2014-08-20. PMID:24291162. |
also phosphatidylserine externalization, augmentation in the level of caspase-3, parp, bad, apaf1 and cleaved caspase-9 along with decreased expression of bcl2 and release of cytochrome c confirmed that, cd(2+) dose dependently induces solely intrinsic pathway of apoptosis in sk-rc-45, independent of jnk. |
2014-08-20 |
2023-08-12 |
human |
| Qing Chen, Rong Zhang, Wei-min Li, Yu-jie Niu, Hui-cai Guo, Xue-hui Liu, Yu-chun Hou, Li-juan Zha. The protective effect of grape seed procyanidin extract against cadmium-induced renal oxidative damage in mice. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:23958968. |
the results showed that cd led to the decrease of sod and gsh-px activities, and the increase of mda level, induced renal apoptosis. |
2014-07-15 |
2023-08-12 |
mouse |
| Abdullah H Al-Assaf, Ali M Alqahtani, Ali A Alshatwi, Naveed A Syed, Gowhar Shafi, Tarique N Hasa. Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24100270. |
however, effects of cd on induction of apoptosis are still elusive. |
2014-07-15 |
2023-08-12 |
human |
| Abdullah H Al-Assaf, Ali M Alqahtani, Ali A Alshatwi, Naveed A Syed, Gowhar Shafi, Tarique N Hasa. Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24100270. |
cd induced p53-dependent apoptosis through cooperation between bak upregulation without changing the bcl-2 and bax expression. |
2014-07-15 |
2023-08-12 |
human |
| Abdullah H Al-Assaf, Ali M Alqahtani, Ali A Alshatwi, Naveed A Syed, Gowhar Shafi, Tarique N Hasa. Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24100270. |
although, this work does not address all the questions regarding the mechanism of cd induced apoptosis, but these findings establish an important role of p53 and mitochondrial function during apoptosis in human lymphocyte. |
2014-07-15 |
2023-08-12 |
human |
| Abdullah H Al-Assaf, Ali M Alqahtani, Ali A Alshatwi, Naveed A Syed, Gowhar Shafi, Tarique N Hasa. Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24100270. |
moreover, based upon our findings, the role of fas in cd induced apoptosis is also undeniable. |
2014-07-15 |
2023-08-12 |
human |
| Abdullah H Al-Assaf, Ali M Alqahtani, Ali A Alshatwi, Naveed A Syed, Gowhar Shafi, Tarique N Hasa. Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3. Environmental toxicology and pharmacology. vol 36. issue 3. 2014-07-15. PMID:24100270. |
hence further investigations are required to understand the different mechanism involved into apoptosis of lymphocytes due to cd exposure. |
2014-07-15 |
2023-08-12 |
human |
| Jian-An Xian, Bin Li, Hui Guo, Yu-Tao Miao, Jian-Min Ye, Li-Na Feng, Chao-Xia Ye, Xun-Bin Pan, An-Li Wang, Xuan-Ming Ha. Haemocyte apoptosis of the tiger shrimp Penaeus monodon exposed to cadmium. Bulletin of environmental contamination and toxicology. vol 92. issue 5. 2014-06-25. PMID:24374743. |
this study investigated the effect of ambient cadmium (cd) on haemocyte apoptosis of the shrimp, penaeus monodon. |
2014-06-25 |
2023-08-12 |
Not clear |
| Jian-An Xian, Bin Li, Hui Guo, Yu-Tao Miao, Jian-Min Ye, Li-Na Feng, Chao-Xia Ye, Xun-Bin Pan, An-Li Wang, Xuan-Ming Ha. Haemocyte apoptosis of the tiger shrimp Penaeus monodon exposed to cadmium. Bulletin of environmental contamination and toxicology. vol 92. issue 5. 2014-06-25. PMID:24374743. |
these results demonstrated that cd(2+) modified esterase activity and induced ros generation, which led to haemocyte apoptosis and thc reduction. |
2014-06-25 |
2023-08-12 |
Not clear |
| Dian Gao, Zhen'e Xu, Xiaoyan Zhang, Chunchao Zhu, Yannan Wang, Weiping Mi. Cadmium triggers kidney cell apoptosis of purse red common carp (Cyprinus carpio) without caspase-8 activation. Developmental and comparative immunology. vol 41. issue 4. 2014-06-23. PMID:23954723. |
in kidney, cadmium (cd) exposure triggered apoptosis and increased caspase-3 and -9 activities, whereas it did not affect caspase-8 activity. |
2014-06-23 |
2023-08-12 |
zebrafish |
| Dian Gao, Zhen'e Xu, Xiaoyan Zhang, Chunchao Zhu, Yannan Wang, Weiping Mi. Cadmium triggers kidney cell apoptosis of purse red common carp (Cyprinus carpio) without caspase-8 activation. Developmental and comparative immunology. vol 41. issue 4. 2014-06-23. PMID:23954723. |
the results reveal that cd can trigger apoptosis, while it cannot activate caspase-8 in purse red common carp. |
2014-06-23 |
2023-08-12 |
zebrafish |
| Piotr Eder, Liliana Lykowska-Szuber, Iwona Krela-Kazmierczak, Kamila Stawczyk-Eder, Karolina Sterzynska, Katarzyna Iwanik, Przemyslaw Majewski, Maciej Zabel, Krzysztof Link. Anti-TNF antibodies do not induce the apoptosis of lamina propria mononuclear cells in uninflamed intestinal tissue in patients with Crohn's disease. Folia histochemica et cytobiologica. vol 51. issue 3. 2014-06-20. PMID:24203631. |
these data show that anti-tnf antibodies rather restore the susceptibility to apoptosis of lpmc in inflamed areas of the gut in cd, than directly induce lpmc apoptosis; otherwise the anti-tnf antibodies should have also induced apoptosis in the uninflamed mucosa. |
2014-06-20 |
2023-08-12 |
Not clear |
| Barbara Poniedziałek, Piotr Rzymski, Jacek Karczewsk. Increased apoptosis of regulatory T cells in Crohn's disease. Hepato-gastroenterology. vol 61. issue 130. 2014-06-19. PMID:24901145. |
this study was aimed to investigate whether the numerical defect of tregs observed in cd resulted from an increased apoptosis of these cells. |
2014-06-19 |
2023-08-13 |
Not clear |
| Chung-Hyun Park, Byung-Hoon Lee, Sang-Gun Ahn, Jung-Hoon Yoon, Seon-Hee O. Serine 9 and tyrosine 216 phosphorylation of GSK-3β differentially regulates autophagy in acquired cadmium resistance. Toxicological sciences : an official journal of the Society of Toxicology. vol 135. issue 2. 2014-06-17. PMID:23897984. |
cd resistance led to interruption of apoptosis and autophagy, as determined by an apoptotic sub-g1 population, procaspase-3 clevage, and lc3-ii induction. |
2014-06-17 |
2023-08-12 |
mouse |
| Chung-Hyun Park, Byung-Hoon Lee, Sang-Gun Ahn, Jung-Hoon Yoon, Seon-Hee O. Serine 9 and tyrosine 216 phosphorylation of GSK-3β differentially regulates autophagy in acquired cadmium resistance. Toxicological sciences : an official journal of the Society of Toxicology. vol 135. issue 2. 2014-06-17. PMID:23897984. |
cd-induced autophagy preceded apoptosis as determined by 3-methyladenine or zvad and time-course experiments after cd treatment. |
2014-06-17 |
2023-08-12 |
mouse |