| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin-Yong Lee, Maki Tokumoto, Yuta Hattori, Yasuyuki Fujiwara, Akinori Shimada, Masahiko Sato. Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes. Toxicological research. vol 32. issue 1. 2016-03-15. PMID:26977261. |
our previous studies indicated that cd induces p53-dependent apoptosis by inhibiting gene expression of the ubiquitin-conjugating enzyme (ube) 2d family in both human and rat proximal tubular cells. |
2016-03-15 |
2023-08-13 |
mouse |
| Jin-Yong Lee, Maki Tokumoto, Yuta Hattori, Yasuyuki Fujiwara, Akinori Shimada, Masahiko Sato. Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes. Toxicological research. vol 32. issue 1. 2016-03-15. PMID:26977261. |
results showed that in the kidney of mice exposed to 300 ppm cd for 12 months, there was overaccumulation of p53 proteins in addition to the induction of apoptosis, which was triggered specifically in the proximal tubules. |
2016-03-15 |
2023-08-13 |
mouse |
| Jin-Yong Lee, Maki Tokumoto, Yuta Hattori, Yasuyuki Fujiwara, Akinori Shimada, Masahiko Sato. Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes. Toxicological research. vol 32. issue 1. 2016-03-15. PMID:26977261. |
in the liver of mice chronically exposed to cd, gene expression of the ube2d family tended to be slightly decreased, together with slight apoptosis without the accumulation of p53 protein. |
2016-03-15 |
2023-08-13 |
mouse |
| Jin-Yong Lee, Maki Tokumoto, Yuta Hattori, Yasuyuki Fujiwara, Akinori Shimada, Masahiko Sato. Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes. Toxicological research. vol 32. issue 1. 2016-03-15. PMID:26977261. |
these results suggest that cd-induced apoptosis through p53 protein is associated with renal toxicity but not hepatic toxicity, and the modification of p53 protein by cd may vary depending on cell type. |
2016-03-15 |
2023-08-13 |
mouse |
| Kong-He Hu, Wen-Xue Li, Min-Ying Sun, She-Bing Zhang, Cai-Xia Fan, Qiang Wu, Wei Zhu, Xin X. Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 36. issue 2. 2016-02-25. PMID:25998312. |
cadmium (cd) induces apoptosis in different kinds of cells, including osteoblasts, both in vivo and in vitro. |
2016-02-25 |
2023-08-13 |
Not clear |
| Kong-He Hu, Wen-Xue Li, Min-Ying Sun, She-Bing Zhang, Cai-Xia Fan, Qiang Wu, Wei Zhu, Xin X. Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 36. issue 2. 2016-02-25. PMID:25998312. |
however, little is known about the mechanisms by which cd induces apoptosis. |
2016-02-25 |
2023-08-13 |
Not clear |
| Piotr Eder, Liliana Łykowska-Szuber, Iwona Krela-Kaźmierczak, Kamila Stawczyk-Eder, Katarzyna Iwanik, Przemysław Majewski, Karolina Sterzyńska, Maciej Zabel, Krzysztof Link. Disturbances in apoptosis of lamina propria lymphocytes in Crohn's disease. Archives of medical science : AMS. vol 11. issue 6. 2016-01-20. PMID:26788091. |
the aim of this study was to assess the potential mechanisms providing resistance to apoptosis of lamina propria lymphocytes (lpl) directlyin intestinal tissues from patients with crohn's disease (cd). |
2016-01-20 |
2023-08-13 |
Not clear |
| Vimal Veeriah, Uttara Saran, Akila Swaminathan, Uma Maheswari Balaguru, Pradeep Thangaraj, Shunmugam Nagarajan, Vinoth Kumar Rajendran, Suvro Chatterje. Cadmium-induced embryopathy: nitric oxide rescues teratogenic effects of cadmium. Toxicological sciences : an official journal of the Society of Toxicology. vol 144. issue 1. 2015-11-30. PMID:25490952. |
cd also caused the down-regulation of foxo1, and up-regulation of foxo3a and caspase 3-mediated apoptosis. |
2015-11-30 |
2023-08-13 |
chicken |
| S D Zagorodnya, G V Baranova, N V Nesterov. [INFLUENCE OF DOXORUBICIN AND ETOPOSIDE ON THE CD 95 MEDIATED APOPTOSIS IN EBV INFECTED LYMPHOMA CELLS BL-41 AND DG-75]. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993). vol 77. issue 4. 2015-10-09. PMID:26422926. |
[influence of doxorubicin and etoposide on the cd 95 mediated apoptosis in ebv infected lymphoma cells bl-41 and dg-75]. |
2015-10-09 |
2023-08-13 |
Not clear |
| S D Zagorodnya, G V Baranova, N V Nesterov. [INFLUENCE OF DOXORUBICIN AND ETOPOSIDE ON THE CD 95 MEDIATED APOPTOSIS IN EBV INFECTED LYMPHOMA CELLS BL-41 AND DG-75]. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993). vol 77. issue 4. 2015-10-09. PMID:26422926. |
the aim of work was to study the effect of anticancer drugs on the process of cd 95 mediated apoptosis in bl-41 and dg-75 infected with epstein-barr virus. |
2015-10-09 |
2023-08-13 |
Not clear |
| Stefanie Steiner, Carolin Daniel, Anika Fischer, Imke Atreya, Simon Hirschmann, Maximilian Waldner, Helmut Neumann, Markus Neurath, Raja Atreya, Benno Weigman. Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative colitis. Archivum immunologiae et therapiae experimentalis. vol 63. issue 1. 2015-09-28. PMID:25155925. |
to address the question whether csa treatment impinges on the induction of cell death, apoptosis assays were performed using cd4(+) t cells from peripheral blood of patients suffering from either uc or cd. |
2015-09-28 |
2023-08-13 |
Not clear |
| Stefanie Steiner, Carolin Daniel, Anika Fischer, Imke Atreya, Simon Hirschmann, Maximilian Waldner, Helmut Neumann, Markus Neurath, Raja Atreya, Benno Weigman. Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative colitis. Archivum immunologiae et therapiae experimentalis. vol 63. issue 1. 2015-09-28. PMID:25155925. |
it became clear that csa treatment resulted in a specific induction of apoptosis in samples from controls and patients with uc but not with cd. |
2015-09-28 |
2023-08-13 |
Not clear |
| Weiming He, Yingfu Li, Jingyan Tian, Ning Jiang, Bo Du, Yuping Pen. Optimized mixture of As, Cd and Pb induce mitochondria-mediated apoptosis in C6-glioma via astroglial activation, inflammation and P38-MAPK. American journal of cancer research. vol 5. issue 8. 2015-09-23. PMID:26396915. |
optimized mixture of as, cd and pb induce mitochondria-mediated apoptosis in c6-glioma via astroglial activation, inflammation and p38-mapk. |
2015-09-23 |
2023-08-13 |
rat |
| Shuang Liu, Feng-ping Xu, Zi-jiang Yang, Ming Li, Ya-hong Min, Shu L. Cadmium-induced injury and the ameliorative effects of selenium on chicken splenic lymphocytes: mechanisms of oxidative stress and apoptosis. Biological trace element research. vol 160. issue 3. 2015-08-28. PMID:25035189. |
the population of apoptosis cells demonstrated that cd induces the apoptosis of chicken splenic lymphocytes; in addition, increased mrna level of bak, p53, caspase-3, caspase-9, and cytochrome c (cyt c) and decreased bcl-2, bcl-xl, and cam were observed in cd treatment group. |
2015-08-28 |
2023-08-13 |
cat |
| Shuang Liu, Feng-ping Xu, Zi-jiang Yang, Ming Li, Ya-hong Min, Shu L. Cadmium-induced injury and the ameliorative effects of selenium on chicken splenic lymphocytes: mechanisms of oxidative stress and apoptosis. Biological trace element research. vol 160. issue 3. 2015-08-28. PMID:25035189. |
in conclusion, concurrent treatment with se reduced the cd-induced morphological changes and oxidative stress, ion disorder, and apoptosis, suggesting that the toxic effects of cd on the chicken splenic lymphocytes were partly meliorated by se. |
2015-08-28 |
2023-08-13 |
cat |
| Yan Yuan, Chenyang Jiang, Feifei Hu, Qiwen Wang, Kangbao Zhang, Yi Wang, Jianhong Gu, Xuezhong Liu, Jianchun Bian, Zongping Li. The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 29. 2015-08-05. PMID:25043952. |
studies have shown that cd induces neuronal apoptosis partially by activating the mitogen-activated protein kinase (mapk) pathways. |
2015-08-05 |
2023-08-13 |
rat |
| Hend M Abo El-Atta, Amal A El-Bakary, Afaf M Attia, Ahmed Lotfy, Shery S Khater, Ayman Z Elsamanoudy, Hussein Abdelaziz Abdall. DNA fragmentation, caspase 3 and prostate-specific antigen genes expression induced by arsenic, cadmium, and chromium on nontumorigenic human prostate cells. Biological trace element research. vol 162. issue 1-3. 2015-07-15. PMID:25227780. |
it can be concluded that as and cd, at low concentrations, can reduce apoptosis of prostatic cells in a concentration-dependent manner while chromium induced it; however, all metal salts used in this study did not induce psa gene expression. |
2015-07-15 |
2023-08-13 |
human |
| Jicang Wang, Huali Zhu, Xuezhong Liu, Zongping Li. Oxidative stress and Ca(2+) signals involved on cadmium-induced apoptosis in rat hepatocyte. Biological trace element research. vol 161. issue 2. 2015-06-29. PMID:25123461. |
studies on nuclear morphology, chromatin condensation, and apoptotic cells demonstrate that cd concentrations ranging within 2.5∼10 μm induced apoptosis. |
2015-06-29 |
2023-08-13 |
rat |
| Jicang Wang, Huali Zhu, Xuezhong Liu, Zongping Li. Oxidative stress and Ca(2+) signals involved on cadmium-induced apoptosis in rat hepatocyte. Biological trace element research. vol 161. issue 2. 2015-06-29. PMID:25123461. |
the early-stage marker of apoptosis, i.e., decreased mitochondrial membrane potential, was observed as early as 1.5 h at 5 μm cd. |
2015-06-29 |
2023-08-13 |
rat |
| Alma Barajas-Espinosa, Ariel Basye, Erin Jesse, Haixu Yan, David Quan, Chun-An Che. Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²⁺-induced apoptosis. Free radical biology & medicine. vol 74. 2015-06-01. PMID:24973647. |
long-term exposure to cd(2+) contributes to dusp4 degradation and the uncontrolled activation of p38 and erk1/2, leading to apoptosis. |
2015-06-01 |
2023-08-13 |
Not clear |