| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongyan Zhao, Wei Liu, Yi Wang, Nannan Dai, Jianhong Gu, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zong-Ping Li. Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways. Journal of veterinary science. vol 16. issue 3. 2016-07-08. PMID:26425111. |
exposure to cadmium (cd) induces apoptosis in osteoblasts (obs); however, little information is available regarding the specific mechanisms of cd-induced primary rat ob apoptosis. |
2016-07-08 |
2023-08-13 |
rat |
| Hongyan Zhao, Wei Liu, Yi Wang, Nannan Dai, Jianhong Gu, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zong-Ping Li. Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways. Journal of veterinary science. vol 16. issue 3. 2016-07-08. PMID:26425111. |
in this study, cd reduced cell viability, damaged cell membranes and induced apoptosis in obs. |
2016-07-08 |
2023-08-13 |
rat |
| Hongyan Zhao, Wei Liu, Yi Wang, Nannan Dai, Jianhong Gu, Yan Yuan, Xuezhong Liu, Jianchun Bian, Zong-Ping Li. Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways. Journal of veterinary science. vol 16. issue 3. 2016-07-08. PMID:26425111. |
taken together, the results of our study clarified that cd has direct cytotoxic effects on obs, which are mediated by caspase- and mapk pathways in cd-induced apoptosis of obs. |
2016-07-08 |
2023-08-13 |
rat |
| Steffen Bank, Paal Skytt Andersen, Johan Burisch, Natalia Pedersen, Stine Roug, Julied Galsgaard, Stine Ydegaard Turino, Jacob Broder Brodersen, Shaista Rashid, Britt Kaiser Rasmussen, Sara Avlund, Thomas Bastholm Olesen, Hans Jürgen Hoffmann, Bjørn Andersen Nexø, Jacob Sode, Ulla Vogel, Vibeke Anderse. Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort. PloS one. vol 10. issue 12. 2016-07-08. PMID:26698117. |
previous studies have shown that polymorphisms in the toll-like receptor (tlr), the apoptosis, the il-23/il-17 and the interferon gamma (ifng) pathways are associated with risk of both cd and uc. |
2016-07-08 |
2023-08-13 |
Not clear |
| Jinxiang Wang, Pingping Zhang, Na Liu, Qian Wang, Jixian Luo, Lan Wan. Cadmium Induces Apoptosis in Freshwater Crab Sinopotamon henanense through Activating Calcium Signal Transduction Pathway. PloS one. vol 10. issue 12. 2016-06-29. PMID:26714174. |
recently, we have found that cd induced apoptosis in gill cells of the freshwater crab sinopotamon henanense via caspase activation. |
2016-06-29 |
2023-08-13 |
Not clear |
| Jinxiang Wang, Pingping Zhang, Na Liu, Qian Wang, Jixian Luo, Lan Wan. Cadmium Induces Apoptosis in Freshwater Crab Sinopotamon henanense through Activating Calcium Signal Transduction Pathway. PloS one. vol 10. issue 12. 2016-06-29. PMID:26714174. |
our data showed that cd triggered gill cell apoptosis which is evidenced by apoptotic dna fragmentation, activations of caspases-3, -8 and -9 and the presence of apoptotic morphological features. |
2016-06-29 |
2023-08-13 |
Not clear |
| Jinxiang Wang, Pingping Zhang, Na Liu, Qian Wang, Jixian Luo, Lan Wan. Cadmium Induces Apoptosis in Freshwater Crab Sinopotamon henanense through Activating Calcium Signal Transduction Pathway. PloS one. vol 10. issue 12. 2016-06-29. PMID:26714174. |
our results indicate that cd evokes gill cell apoptosis through activating ca2+-cam signaling transduction pathway. |
2016-06-29 |
2023-08-13 |
Not clear |
| Małgorzata Zielińska-Przyjemska, Anna Olejnik, Agnieszka Dobrowolska-Zachwieja, Michał Łuczak, Wanda Baer-Dubowsk. DNA damage and apoptosis in blood neutrophils of inflammatory bowel disease patients and in Caco-2 cells in vitro exposed to betanin. Postepy higieny i medycyny doswiadczalnej (Online). vol 70. 2016-06-24. PMID:27117102. |
the aim of the present study was to evaluate the effects of betanin on the oxidative dna damage and apoptosis in neutrophils isolated from blood of patients with inflammatory bowel disease--ulcerative colitis (uc) and crohn's disease (cd). |
2016-06-24 |
2023-08-13 |
human |
| Chong Xu, Hai Zhang, Chunxiao Liu, Yu Zhu, Xiaoxue Wang, Wei Gao, Shile Huang, Long Che. Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium. Oncotarget. vol 6. issue 25. 2016-06-10. PMID:26046303. |
the results uncover that rapamycin inhibits cd activation of erk1/2-mediated neuronal apoptosis through intervening mtor-pp2a/pten signaling network. |
2016-06-10 |
2023-08-13 |
Not clear |
| Xiaolong Gu, Rongrong Chen, Guoliang Hu, Yu Zhuang, Junrong Luo, Caiying Zhang, Xiaoquan Guo, Aiming Huang, Huabin Ca. Cell apoptosis of caprine spleen induced by toxicity of cadmium with different levels of molybdenum. Environmental toxicology and pharmacology. vol 40. issue 1. 2016-06-07. PMID:26068552. |
in order to clarify the effects of the combination of mo and cd on goat and relationship between the two elements, combined chronic toxicity of cadmium with different levels of molybdenum in vivo on apoptosis gene and ultrastructure of spleen was evaluated with the methods of rt-qpcr and transmission electron microscopy. |
2016-06-07 |
2023-08-13 |
Not clear |
| Lili Liu, Bingyou Yang, Yupeng Cheng, Hongjin Li. Ameliorative Effects of Selenium on Cadmium-Induced Oxidative Stress and Endoplasmic Reticulum Stress in the Chicken Kidney. Biological trace element research. vol 167. issue 2. 2016-06-03. PMID:25805271. |
then, the histopathological changes, cd and se contents, levels of oxidative stress, inducible nitric oxide synthase-nitric oxide (inos-no) system activity, levels of endoplasmic reticulum (er) stress, results of the terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay of apoptosis, and expression levels of bcl-2 and caspase 3 in the kidney were examined. |
2016-06-03 |
2023-08-13 |
human |
| Lili Liu, Bingyou Yang, Yupeng Cheng, Hongjin Li. Ameliorative Effects of Selenium on Cadmium-Induced Oxidative Stress and Endoplasmic Reticulum Stress in the Chicken Kidney. Biological trace element research. vol 167. issue 2. 2016-06-03. PMID:25805271. |
the results showed that cd exposure caused histopathological and ultrastructural damage and apoptosis of the kidneys. |
2016-06-03 |
2023-08-13 |
human |
| Lili Liu, Bingyou Yang, Yupeng Cheng, Hongjin Li. Ameliorative Effects of Selenium on Cadmium-Induced Oxidative Stress and Endoplasmic Reticulum Stress in the Chicken Kidney. Biological trace element research. vol 167. issue 2. 2016-06-03. PMID:25805271. |
cd administration significantly increased the accumulation of cd, the malondialdehyde (mda) content, no production, inos activity, inos expression levels, expression levels of er stress-related genes (grp78, grp94, atf4, atf6, and ire) and the pro-apoptosis gene caspase 3, and the rate of apoptosis. |
2016-06-03 |
2023-08-13 |
human |
| Lili Liu, Bingyou Yang, Yupeng Cheng, Hongjin Li. Ameliorative Effects of Selenium on Cadmium-Induced Oxidative Stress and Endoplasmic Reticulum Stress in the Chicken Kidney. Biological trace element research. vol 167. issue 2. 2016-06-03. PMID:25805271. |
co-treatment with se and cd obviously reduced the accumulation of cd, cd-induced histopathological and ultrastructural changes, oxidative stress, inos-no system activity, er stress, caspase 3 expression levels, and the rate of apoptosis in the kidneys. |
2016-06-03 |
2023-08-13 |
human |
| Qi-Wen Wang, Yi Wang, Tao Wang, Kang-Bao Zhang, Yan Yuan, Jian-Chun Bian, Xue-Zhong Liu, Jian-Hong Gu, Jia-Qiao Zhu, Zong-Ping Li. Cadmium-induced autophagy is mediated by oxidative signaling in PC-12 cells and is associated with cytoprotection. Molecular medicine reports. vol 12. issue 3. 2016-05-17. PMID:26062759. |
recently, exposure of pc-12 cells to cd has been shown to activate autophagy, which acts as a temporary survival pathway under stressful conditions by delaying the occurrence of apoptosis. |
2016-05-17 |
2023-08-13 |
Not clear |
| Qi-Wen Wang, Yi Wang, Tao Wang, Kang-Bao Zhang, Yan Yuan, Jian-Chun Bian, Xue-Zhong Liu, Jian-Hong Gu, Jia-Qiao Zhu, Zong-Ping Li. Cadmium-induced autophagy is mediated by oxidative signaling in PC-12 cells and is associated with cytoprotection. Molecular medicine reports. vol 12. issue 3. 2016-05-17. PMID:26062759. |
the results demonstrated that cd‑induced autophagy (following treatment with cd for 4 h), increased the levels of intracellular reactive oxygen species (ros), decreased the mitochondrial membrane potential and resulted in apoptosis. |
2016-05-17 |
2023-08-13 |
Not clear |
| Xiaohong Liu, Chunhe Guo, Yumao Huang, Xiaoyu Zhang, Yaosheng Che. Inhibition of porcine reproductive and respiratory syndrome virus by Cecropin D in vitro. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. vol 34. 2016-05-13. PMID:26102162. |
cd also attenuated virus-induced apoptosis during the late phase of prrsv infection and suppressed virus release in marc-145 cells, which might contribute to the inhibition of prrsv infection. |
2016-05-13 |
2023-08-13 |
Not clear |
| Lixin Wang, Xiaoyan Wang, Shuping Zhang, Guangbo Qu, Sijin Li. A protective role of heme-regulated eIF2α kinase in cadmium-induced toxicity in erythroid cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 62. 2016-05-06. PMID:24161693. |
upon cd treatment, hri-eif2αp-atf4 signaling was activated to protect cells from cell death and differentiation attenuation in wt fetal liver erythroblasts; in contrast, hri(-/-) erythroblasts suffered from enhanced oxidative stress, as evidenced by increased levels of reactive oxygen species (ros) and consequentially elevated apoptosis. |
2016-05-06 |
2023-08-12 |
mouse |
| Zhimin Chen, Dawei Gu, Ming Zhou, Hui Shi, Shu Yan, Yunqing Ca. Regulatory role of miR-125a/b in the suppression by selenium of cadmium-induced apoptosis via the mitochondrial pathway in LLC-PK1 cells. Chemico-biological interactions. vol 243. 2016-05-02. PMID:26607349. |
the effects of downregulation of mir-125a/b on apoptosis were similar to those of cd treatment, and both effects were inhibited by se. |
2016-05-02 |
2023-08-13 |
Not clear |
| Fuhong Liu, Bei Wang, Liqun Li, Fengyun Dong, Xiaocui Chen, Yan Li, Xiuzhen Dong, Youichiro Wada, Carolyn M Kapron, Ju Li. Low-Dose Cadmium Upregulates VEGF Expression in Lung Adenocarcinoma Cells. International journal of environmental research and public health. vol 12. issue 9. 2016-04-08. PMID:26343694. |
cd does not affect proliferation, migration, or apoptosis of a549 cells at concentrations of 0.1-10 μm. |
2016-04-08 |
2023-08-13 |
human |